Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Brisson D, Ledoux K, Bossé Y, St-Pierre J, Julien P, Perron P, Hudson TJ, Vohl MC, Gaudet D. Effect of apolipoprotein E, peroxisome proliferator-activated receptor alpha and lipoprotein lipase gene mutations on the ability of fenofibrate to improve lipid profiles and reach clinical guideline targets among hypertriglyceridemic patients. Pharmacogenetics. 2002 Jun;12(4):313-20. doi: 10.1097/00008571-200206000-00007. PubMed PMID: 12042669.
Bossé Y, Pascot A, Dumont M, Brochu M, Prud'homme D, Bergeron J, Després JP, Vohl MC. Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil. Genet Med. 2002 Jul-Aug;4(4):311-5. doi: 10.1097/00125817-200207000-00010. PubMed PMID: 12172398.
Bossé Y, Vohl MC, Dumont M, Brochu M, Bergeron J, Després JP, Prud'homme D. Influence of the angiotensin-converting enzyme gene insertion/deletion polymorphism on lipoprotein/lipid response to gemfibrozil. Clin Genet. 2002 Jul;62(1):45-52. doi: 10.1034/j.1399-0004.2002.620106.x. PubMed PMID: 12123487.
Bossé Y, Pérusse L, Després JP, Lamarche B, Chagnon YC, Rice T, Rao DC, Bouchard C, Vohl MC. Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter. Circulation. 2003 May 13;107(18):2361-8. doi: 10.1161/01.CIR.0000065577.60129.F5. Epub 2003 May 5. PubMed PMID: 12732599.
Bossé Y, Després JP, Bouchard C, Pérusse L, Vohl MC. The peroxisome proliferator-activated receptor alpha L162V mutation is associated with reduced adiposity. Obes Res. 2003 Jul;11(7):809-16. doi: 10.1038/oby.2003.112. PubMed PMID: 12855749.
Paradis ME, Couture P, Bosse Y, Despres JP, Perusse L, Bouchard C, Vohl MC, Lamarche B. The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women. J Lipid Res. 2003 Oct;44(10):1902-8. doi: 10.1194/jlr.M300118-JLR200. Epub 2003 Jul 16. PubMed PMID: 12867537.
Bossé Y, Weisnagel SJ, Bouchard C, Després JP, Pérusse L, Vohl MC. Combined effects of PPARgamma2 P12A and PPARalpha L162V polymorphisms on glucose and insulin homeostasis: the Québec Family Study. J Hum Genet. 2003;48(12):614-621. doi: 10.1007/s10038-003-0087-2. Epub 2003 Nov 20. PubMed PMID: 14677049.
Bossé Y, Vohl MC, Després JP, Lamarche B, Rice T, Rao DC, Bouchard C, Pérusse L. Heritability of LDL peak particle diameter in the Quebec Family Study. Genet Epidemiol. 2003 Dec;25(4):375-81. doi: 10.1002/gepi.10272. PubMed PMID: 14639707.
Bossé Y, Chagnon YC, Després JP, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study. J Lipid Res. 2004 Mar;45(3):419-26. doi: 10.1194/jlr.M300401-JLR200. Epub 2003 Dec 16. PubMed PMID: 14679165.
Bossé Y, Pérusse L, Vohl MC. Genetics of LDL particle heterogeneity: from genetic epidemiology to DNA-based variations. J Lipid Res. 2004 Jun;45(6):1008-26. doi: 10.1194/jlr.R400002-JLR200. Epub 2004 Apr 1. Review. PubMed PMID: 15060093.
Brouillette C, Bossé Y, Pérusse L, Gaudet D, Vohl MC. Effect of liver fatty acid binding protein (FABP) T94A missense mutation on plasma lipoprotein responsiveness to treatment with fenofibrate. J Hum Genet. 2004;49(8):424-432. doi: 10.1007/s10038-004-0171-2. Epub 2004 Jul 13. PubMed PMID: 15249972.
Bossé Y, Chagnon YC, Després JP, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Compendium of genome-wide scans of lipid-related phenotypes: adding a new genome-wide search of apolipoprotein levels. J Lipid Res. 2004 Dec;45(12):2174-84. doi: 10.1194/jlr.R400008-JLR200. Epub 2004 Sep 16. Review. PubMed PMID: 15375185.
Paradis AM, Fontaine-Bisson B, Bossé Y, Robitaille J, Lemieux S, Jacques H, Lamarche B, Tchernof A, Couture P, Vohl MC. The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men. Am J Clin Nutr. 2005 Feb;81(2):523-30. doi: 10.1093/ajcn.81.2.523. PubMed PMID: 15699244.
Bossé Y, Feitosa MF, Després JP, Lamarche B, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Detection of a major gene effect for LDL peak particle diameter and association with apolipoprotein H gene haplotype. Atherosclerosis. 2005 Oct;182(2):231-9. doi: 10.1016/j.atherosclerosis.2005.02.008. PubMed PMID: 16159595.
Bossé Y, Bouchard L, Després JP, Bouchard C, Pérusse L, Vohl MC. Haplotypes in the phospholipid transfer protein gene are associated with obesity-related phenotypes: the Québec Family Study. Int J Obes (Lond). 2005 Nov;29(11):1338-45. doi: 10.1038/sj.ijo.0803010. PubMed PMID: 15953936.
Thompson MD, Takasaki J, Capra V, Rovati GE, Siminovitch KA, Burnham WM, Hudson TJ, Bossé Y, Cole DE. G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective. Mol Diagn Ther. 2006;10(6):353-66. doi: 10.1007/BF03256212. Review. PubMed PMID: 17154652.
Bossé Y, Hudson TJ. Toward a comprehensive set of asthma susceptibility genes. Annu Rev Med. 2007;58:171-84. doi: 10.1146/ Review. PubMed PMID: 16907639.
Zhang Y, Bossé Y, Marceau P, Biron S, Lebel S, Richard D, Vohl MC, Tchernof A. Gene expression variability in subcutaneous and omental adipose tissue of obese men. Gene Expr. 2007;14(1):35-46. doi: 10.3727/000000007783991772. PubMed PMID: 17933217; PubMed Central PMCID: PMC6042019.
Bossé Y, Després JP, Chagnon YC, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Quantitative trait locus on 15q for a metabolic syndrome variable derived from factor analysis. Obesity (Silver Spring). 2007 Mar;15(3):544-50. doi: 10.1038/oby.2007.577. PubMed PMID: 17372302.
Bossé Y, Maghni K, Hudson TJ. 1alpha,25-dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility, and remodeling processes. Physiol Genomics. 2007 Apr 24;29(2):161-8. doi: 10.1152/physiolgenomics.00134.2006. Epub 2007 Jan 9. PubMed PMID: 17213369.
Bossé Y, Mathieu P, Pibarot P. Reply to a letter to the editor re: Genomics of aortic valve disease. Journal of the American College of Cardiology. 2008; 52:498-9.
Al-Shemari H, Bossé Y, Hudson TJ, Cabaluna M, Duval M, Lemire M, Vallee-Smedja S, Frenkiel S, Desrosiers M. Influence of leukotriene gene polymorphisms on chronic rhinosinusitis. BMC Med Genet. 2008 Mar 26;9:21. doi: 10.1186/1471-2350-9-21. PubMed PMID: 18366797; PubMed Central PMCID: PMC2292155.
Bossé Y, Mathieu P, Pibarot P. Genomics: the next step to elucidate the etiology of calcific aortic valve stenosis. J Am Coll Cardiol. 2008 Apr 8;51(14):1327-36. doi: 10.1016/j.jacc.2007.12.031. Review. PubMed PMID: 18387432.
Tewfik MA, Bossé Y, Hudson TJ, Vallée-Smejda S, Al-Shemari H, Desrosiers M. Assessment of Toll-like receptor 2 gene polymorphisms in severe chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 2008 Aug;37(4):552-8. PubMed PMID: 19128592.
Cormier C, Bossé Y, Mfuna L, Hudson TJ, Desrosiers M. Polymorphisms in the tumour necrosis factor alpha-induced protein 3 (TNFAIP3) gene are associated with chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 2009 Feb;38(1):133-41. PubMed PMID: 19344623.
Bossé Y. Genetics of chronic obstructive pulmonary disease: a succinct review, future avenues and prospective clinical applications. Pharmacogenomics. 2009 Apr;10(4):655-67. doi: 10.2217/pgs.09.10. Review. PubMed PMID: 19374520.
Bossé Y, Bacot F, Montpetit A, Rung J, Qu HQ, Engert JC, Polychronakos C, Hudson TJ, Froguel P, Sladek R, Desrosiers M. Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. Hum Genet. 2009 Apr;125(3):305-18. doi: 10.1007/s00439-009-0626-9. Epub 2009 Jan 29. PubMed PMID: 19184112.
Tewfik MA, Bossé Y, Lemire M, Hudson TJ, Vallée-Smejda S, Al-Shemari H, Laprise C, Desrosiers M. Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE. Allergy. 2009 May;64(5):746-53. doi: 10.1111/j.1398-9995.2008.01889.x. Epub 2009 Feb 27. PubMed PMID: 19254290.
Endam LM, Bossé Y, Filali-Mouhim A, Cormier C, Boisvert P, Boulet LP, Hudson TJ, Desrosiers M. Polymorphisms in the interleukin-22 receptor alpha-1 gene are associated with severe chronic rhinosinusitis. Otolaryngol Head Neck Surg. 2009 May;140(5):741-7. doi: 10.1016/j.otohns.2008.12.058. Epub 2009 Feb 28. PubMed PMID: 19393422.
Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ. Analyses of associations with asthma in four asthma population samples from Canada and Australia. Hum Genet. 2009 May;125(4):445-59. doi: 10.1007/s00439-009-0643-8. Epub 2009 Feb 27. PubMed PMID: 19247692.
Castano R, Bossé Y, Endam LM, Desrosiers M. Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis. Am J Rhinol Allergy. 2009 Jul-Aug;23(4):377-84. doi: 10.2500/ajra.2009.23.3303. PubMed PMID: 19671251.
He JQ, Hallstrand TS, Knight D, Chan-Yeung M, Sandford A, Tripp B, Zamar D, Bossé Y, Kozyrskyj AL, James A, Laprise C, Daley D. A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness. J Allergy Clin Immunol. 2009 Aug;124(2):222-9. doi: 10.1016/j.jaci.2009.04.018. Epub 2009 Jun 21. PubMed PMID: 19539984.
Bossé Y, Miqdad A, Fournier D, Pépin A, Pibarot P, Mathieu P. Refining molecular pathways leading to calcific aortic valve stenosis by studying gene expression profile of normal and calcified stenotic human aortic valves. Circ Cardiovasc Genet. 2009 Oct;2(5):489-98. doi: 10.1161/CIRCGENETICS.108.820795. Epub 2009 Jul 8. PubMed PMID: 20031625.
Bossé Y, Lemire M, Poon AH, Daley D, He JQ, Sandford A, White JH, James AL, Musk AW, Palmer LJ, Raby BA, Weiss ST, Kozyrskyj AL, Becker A, Hudson TJ, Laprise C. Asthma and genes encoding components of the vitamin D pathway. Respir Res. 2009 Oct 24;10(1):98. doi: 10.1186/1465-9921-10-98. PubMed PMID: 19852851; PubMed Central PMCID: PMC2779188.
Kilty SJ, Bossé Y, Cormier C, Endam LM, Desrosiers MY. Polymorphisms in the SERPINA1 (Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy. Am J Rhinol Allergy. 2010 Jan-Feb;24(1):e4-9. doi: 10.2500/ajra.2010.24.3429. PubMed PMID: 20109307.
Tewfik MA, Bossé Y, Al-Shemari H, Desrosiers M. Genetics of chronic rhinosinusitis: a primer. J Otolaryngol Head Neck Surg. 2010 Feb;39(1):62-8. Review. PubMed PMID: 20122347.
Mfuna Endam L, Cormier C, Bossé Y, Filali-Mouhim A, Desrosiers M. Association of IL1A, IL1B, and TNF gene polymorphisms with chronic rhinosinusitis with and without nasal polyposis: A replication study. Arch Otolaryngol Head Neck Surg. 2010 Feb;136(2):187-92. doi: 10.1001/archoto.2009.219. PubMed PMID: 20157068.
Tournas A, Mfuna L, Bossé Y, Filali-Mouhim A, Grenier JP, Desrosiers M. A pooling-based genome-wide association study implicates the p73 gene in chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 2010 Apr;39(2):188-95. PubMed PMID: 20211107.
Castano R, Bossé Y, Endam LM, Filali-Mouhim A, Desrosiers M. c-MET pathway involvement in chronic rhinosinusitis: a genetic association analysis. Otolaryngol Head Neck Surg. 2010 May;142(5):665-71.e1-2. doi: 10.1016/j.otohns.2010.01.004. PubMed PMID: 20416453.
Derbali H, Bossé Y, Côté N, Pibarot P, Audet A, Pépin A, Arsenault B, Couture C, Després JP, Mathieu P. Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2. Am J Pathol. 2010 Jun;176(6):2638-45. doi: 10.2353/ajpath.2010.090541. Epub 2010 Apr 9. PubMed PMID: 20382708; PubMed Central PMCID: PMC2877827.
Bossé Y, Sin DD, Laviolette M, Sandford A, Hogg J, Daley D, Franke L, Nickle D, Hao K, Timens W, Postma D, Pare PD. Hypothesis-driven research on genomic data derived from a large scale lung eQTL mapping study. WebmedCentral LUNG. 2010 September; 1(9):WMC00724.
Zhang Y, Endam LM, Filali-Mouhim A, Bossé Y, Castano R, Desrosiers M. Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis. Am J Rhinol Allergy. 2011 Mar-Apr;25(2):e49-54. doi: 10.2500/ajra.2011.25.3588. PubMed PMID: 21679499.
Guauque-Olarte S, Gaudreault N, Piché MÈ, Fournier D, Mauriège P, Mathieu P, Bossé Y. The transcriptome of human epicardial, mediastinal and subcutaneous adipose tissues in men with coronary artery disease. PLoS One. 2011;6(5):e19908. doi: 10.1371/journal.pone.0019908. Epub 2011 May 16. PubMed PMID: 21603615; PubMed Central PMCID: PMC3095619.
Gaudreault N, Ducharme V, Lamontagne M, Guauque-Olarte S, Mathieu P, Pibarot P, Bossé Y. Replication of genetic association studies in aortic stenosis in adults. Am J Cardiol. 2011 Nov 1;108(9):1305-10. doi: 10.1016/j.amjcard.2011.06.050. Epub 2011 Aug 18. PubMed PMID: 21855833.
Bossé Y. Highlights from the latest articles in chronic obstructive pulmonary disease genetics. Personalized Medicine. 2012; 9(2):181-4.
Côté N, El Husseini D, Pépin A, Guauque-Olarte S, Ducharme V, Bouchard-Cannon P, Audet A, Fournier D, Gaudreault N, Derbali H, McKee MD, Simard C, Després JP, Pibarot P, Bossé Y, Mathieu P. ATP acts as a survival signal and prevents the mineralization of aortic valve. J Mol Cell Cardiol. 2012 May;52(5):1191-202. doi: 10.1016/j.yjmcc.2012.02.003. Epub 2012 Feb 16. PubMed PMID: 22366713.
Bossé Y, Postma DS, Sin DD, Lamontagne M, Couture C, Gaudreault N, Joubert P, Wong V, Elliott M, van den Berge M, Brandsma CA, Tribouley C, Malkov V, Tsou JA, Opiteck GJ, Hogg JC, Sandford AJ, Timens W, Paré PD, Laviolette M. Molecular signature of smoking in human lung tissues. Cancer Res. 2012 Aug 1;72(15):3753-63. doi: 10.1158/0008-5472.CAN-12-1160. Epub 2012 Jun 1. PubMed PMID: 22659451.
Bossé Y. Updates on the COPD gene list. Int J Chron Obstruct Pulmon Dis. 2012;7:607-31. doi: 10.2147/COPD.S35294. Epub 2012 Sep 18. Review. PubMed PMID: 23055711; PubMed Central PMCID: PMC3459654.
Audet A, Côté N, Couture C, Bossé Y, Després JP, Pibarot P, Mathieu P. Amyloid substance within stenotic aortic valves promotes mineralization. Histopathology. 2012 Oct;61(4):610-9. doi: 10.1111/j.1365-2559.2012.04265.x. PubMed PMID: 22642224.
Hao K, Bossé Y, Nickle DC, Paré PD, Postma DS, Laviolette M, Sandford A, Hackett TL, Daley D, Hogg JC, Elliott WM, Couture C, Lamontagne M, Brandsma CA, van den Berge M, Koppelman G, Reicin AS, Nicholson DW, Malkov V, Derry JM, Suver C, Tsou JA, Kulkarni A, Zhang C, Vessey R, Opiteck GJ, Curtis SP, Timens W, Sin DD. Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS Genet. 2012;8(11):e1003029. doi: 10.1371/journal.pgen.1003029. Epub 2012 Nov 29. PubMed PMID: 23209423; PubMed Central PMCID: PMC3510026.
What would you like to do?