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Nishimura K, Sanchez-Molano J, Kerr N, Pressman Y, Silvera R, Khan A, Gajavelli S, Bramlett HM, Dietrich WD. Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury. J Neurotrauma. 2024 Apr 15;. doi: 10.1089/neu.2023.0650. [Epub ahead of print] PubMed PMID: 38445369.
Aklepi G, Manolovitz B, Robayo LE, Sarafraz A, Blandino CF, Arwari B, Sobczak E, Bass D, Ghamasaee P, Bolaños Saavedra A, Samano D, Massad N, Kottapally M, Merenda A, Dib S, Dietrich WD, Rundek T, O'Phelan KH, Claassen J, Walker MF, Alkhachroum A. Covert Tracking to Immersive Stimuli in Traumatic Brain Injury Subjects With Disorders of Consciousness. J Neurotrauma. 2024 Mar;41(5-6):646-659. doi: 10.1089/neu.2023.0188. Epub 2023 Oct 16. PubMed PMID: 37624747.
Vontell RT, Gober R, Dallmeier J, Brzostowicki D, Barreda A, Blennow K, Zetterberg H, Kvartsberg H, Gultekin SH, de Rivero Vaccari JP, Bramlett HM, Dietrich WD, Keane RW, Davis DA, Rundek T, Sun X. Association of region-specific hippocampal reduction of neurogranin with inflammasome proteins in post mortem brains of Alzheimer's disease. Alzheimers Dement (N Y). 2024 Jan-Mar;10(1):e12444. doi: 10.1002/trc2.12444. eCollection 2024 Jan-Mar. PubMed PMID: 38356472; PubMed Central PMCID: PMC10865487.
Rincon Sabatino S, Sangaletti R, Griswold A, Dietrich WD, King CS, Rajguru SM. Transcriptional response to mild therapeutic hypothermia in noise-induced cochlear injury. Front Neurosci. 2023;17:1296475. doi: 10.3389/fnins.2023.1296475. eCollection 2023. PubMed PMID: 38298897; PubMed Central PMCID: PMC10827921.
Rincon Sabatino S, Rivero A, Sangaletti R, Dietrich WD, Hoffer ME, King CS, Rajguru SM. Targeted therapeutic hypothermia protects against noise induced hearing loss. Front Neurosci. 2023;17:1296458. doi: 10.3389/fnins.2023.1296458. eCollection 2023. PubMed PMID: 38292902; PubMed Central PMCID: PMC10826421.
Munoz Pareja JC, de Rivero Vaccari JP, Chavez MM, Kerrigan M, Pringle C, Guthrie K, Swaby K, Coto J, Kobeissy F, Avery KL, Ghosh S, Dhanashree R, Shanmugham P, Lautenslager LA, Faulkenberry S, Pareja Zabala MC, Al Fakhri N, Loor-Torres R, Governale LS, Blatt JE, Gober J, Perez PK, Solano J, McCrea H, Thorson C, O'Phelan KH, Keane RW, Dietrich WD, Wang KK. Prognostic and Diagnostic Utility of Serum Biomarkers in Pediatric Traumatic Brain Injury. J Neurotrauma. 2024 Jan;41(1-2):106-122. doi: 10.1089/neu.2023.0039. Epub 2023 Nov 2. PubMed PMID: 37646421; PubMed Central PMCID: PMC11071081.
Johnson NH, Kerr NA, de Rivero Vaccari JP, Bramlett HM, Keane RW, Dietrich WD. Genetic predisposition to Alzheimer's disease alters inflammasome activity after traumatic brain injury. Transl Res. 2023 Jul;257:66-77. doi: 10.1016/j.trsl.2023.02.001. Epub 2023 Feb 8. PubMed PMID: 36758791; PubMed Central PMCID: PMC10192027.
Vontell RT, de Rivero Vaccari JP, Sun X, Gultekin SH, Bramlett HM, Dietrich WD, Keane RW. Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease. Brain Pathol. 2023 Jul;33(4):e13142. doi: 10.1111/bpa.13142. Epub 2022 Dec 29. PubMed PMID: 36579934; PubMed Central PMCID: PMC10307529.
Govindarajan V, Shah AH, Morell AA, Borowy V, Ingle SM, Mendez Valdez MJ, Rivas S, Eichberg DG, Luther E, Lu V, Heiss J, Komotar RJ, Levi AD. Predicting Academic Career Placement via Development of Novel Intra-residency Metrics. World Neurosurg. 2023 Jun;174:e35-e43. doi: 10.1016/j.wneu.2023.02.080. Epub 2023 Feb 24. PubMed PMID: 36841537; PubMed Central PMCID: PMC10350854.
Johnson NH, de Rivero Vaccari JP, Bramlett HM, Keane RW, Dietrich WD. Inflammasome activation in traumatic brain injury and Alzheimer's disease. Transl Res. 2023 Apr;254:1-12. doi: 10.1016/j.trsl.2022.08.014. Epub 2022 Sep 5. Review. PubMed PMID: 36070840; PubMed Central PMCID: PMC10353562.
Kattan D, Barsa C, Mekhijian S, Shakkour Z, Jammoul M, Doumit M, Zabala MCP, Darwiche N, Eid AH, Mechref Y, Wang KK, de Rivero Vaccari JP, Munoz Pareja JC, Kobeissy F. Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview. Neurosci Biobehav Rev. 2023 Jan;144:104969. doi: 10.1016/j.neubiorev.2022.104969. Epub 2022 Nov 22. Review. PubMed PMID: 36423707; PubMed Central PMCID: PMC9805531.
Johnson NH, Hadad R, Taylor RR, Rodríguez Pilar J, Salazar O, Llompart-Pou JA, Dietrich WD, Keane RW, Pérez-Bárcena J, de Rivero Vaccari JP. Inflammatory Biomarkers of Traumatic Brain Injury. Pharmaceuticals (Basel). 2022 May 25;15(6). doi: 10.3390/ph15060660. PubMed PMID: 35745576; PubMed Central PMCID: PMC9227014.
Gant KL, Guest JD, Palermo AE, Vedantam A, Jimsheleishvili G, Bunge MB, Brooks AE, Anderson KD, Thomas CK, Santamaria AJ, Perez MA, Curiel R, Nash MS, Saraf-Lavi E, Pearse DD, Widerström-Noga E, Khan A, Dietrich WD, Levi AD. Phase 1 Safety Trial of Autologous Human Schwann Cell Transplantation in Chronic Spinal Cord Injury. J Neurotrauma. 2022 Feb;39(3-4):285-299. doi: 10.1089/neu.2020.7590. Epub 2021 May 3. PubMed PMID: 33757304; PubMed Central PMCID: PMC9360180.
Khan A, Diaz A, Brooks AE, Burks SS, Athauda G, Wood P, Lee YS, Silvera R, Donaldson M, Pressman Y, Anderson KD, Bunge MB, Pearse DD, Dietrich WD, Guest JD, Levi AD. Scalable culture techniques to generate large numbers of purified human Schwann cells for clinical trials in human spinal cord and peripheral nerve injuries. J Neurosurg Spine. 2022 Jan 1;36(1):135-144. doi: 10.3171/2020.11.SPINE201433. Print 2022 Jan 1. PubMed PMID: 34479193; PubMed Central PMCID: PMC10193489.
Osier ND, Bramlett HM, Shear DA, Mondello S, Carlson SW, Dietrich WD, Deng-Bryant Y, Wang KKW, Hayes RL, Yang Z, Empey PE, Poloyac SM, Lafrenaye AD, Povlishock JT, Gilsdorf JS, Kochanek PM, Dixon CE. Kollidon VA64 Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. J Neurotrauma. 2021 Sep 1;38(17):2454-2472. doi: 10.1089/neu.2021.0089. Epub 2021 May 14. PubMed PMID: 33843262.
Radabaugh H, Bonnell J, Schwartz O, Sarkar D, Dietrich WD, Bramlett HM. Use of Machine Learning to Re-Assess Patterns of Multivariate Functional Recovery after Fluid Percussion Injury: Operation Brain Trauma Therapy. J Neurotrauma. 2021 Jun 15;38(12):1670-1678. doi: 10.1089/neu.2020.7357. Epub 2021 Jan 13. PubMed PMID: 33107380; PubMed Central PMCID: PMC8165458.
Khan A, Bellio MA, Schulman IH, Levi AD, Longsomboon B, Brooks A, Valasaki K, DiFede DL, Pujol MV, Yavagal DR, Bates KE, Si MS, Kaushal S, Green BA, Anderson KD, Guest JD, Burks SS, Silvera R, Santamaria AJ, Lalwani A, Dietrich WD, Hare JM. The Interdisciplinary Stem Cell Institute's Use of Food and Drug Administration-Expanded Access Guidelines to Provide Experimental Cell Therapy to Patients With Rare Serious Diseases. Front Cell Dev Biol. 2021;9:675738. doi: 10.3389/fcell.2021.675738. eCollection 2021. PubMed PMID: 34169074; PubMed Central PMCID: PMC8217825.
Singh J, Barrett J, Sangaletti R, Dietrich WD, Rajguru SM. Additive Protective Effects of Delayed Mild Therapeutic Hypothermia and Antioxidants on PC12 Cells Exposed to Oxidative Stress. Ther Hypothermia Temp Manag. 2021 Jun;11(2):77-87. doi: 10.1089/ther.2019.0034. Epub 2020 Apr 17. PubMed PMID: 32302519; PubMed Central PMCID: PMC8215413.
Ali A, Zambrano R, Duncan MR, Chen S, Luo S, Yuan H, Chen P, Benny M, Schmidt A, Young K, Kerr N, de Rivero Vaccari JP, Keane RW, Dietrich WD, Wu S. Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats. Sci Rep. 2021 Apr 22;11(1):8791. doi: 10.1038/s41598-021-87706-w. PubMed PMID: 33888735; PubMed Central PMCID: PMC8062626.
Jha RM, Mondello S, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Wang KKW, Yang Z, Hayes RL, Poloyac SM, Empey PE, Lafrenaye AD, Yan HQ, Carlson SW, Povlishock JT, Gilsdorf JS, Kochanek PM. Glibenclamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. J Neurotrauma. 2021 Mar;38(5):628-645. doi: 10.1089/neu.2020.7421. Epub 2020 Dec 18. PubMed PMID: 33203303; PubMed Central PMCID: PMC8418525.
Kerr NA, de Rivero Vaccari JP, Weaver C, Dietrich WD, Ahmed T, Keane RW. Enoxaparin Attenuates Acute Lung Injury and Inflammasome Activation after Traumatic Brain Injury. J Neurotrauma. 2021 Mar;38(5):646-654. doi: 10.1089/neu.2020.7257. Epub 2020 Aug 11. PubMed PMID: 32669032; PubMed Central PMCID: PMC7898405.
Wasserman J, McGuire LS, Sick T, Bramlett HM, Dietrich WD. An Exploratory Report on Electrographic Changes in the Cerebral Cortex Following Mild Traumatic Brain Injury with Hyperthermia in the Rat. Ther Hypothermia Temp Manag. 2021 Mar;11(1):10-18. doi: 10.1089/ther.2020.0002. Epub 2020 May 5. PubMed PMID: 32366168; PubMed Central PMCID: PMC7910421.
Chen SH, Scott XO, Ferrer Marcelo Y, Almeida VW, Blackwelder PL, Yavagal DR, Peterson EC, Starke RM, Dietrich WD, Keane RW, de Rivero Vaccari JP. Netosis and Inflammasomes in Large Vessel Occlusion Thrombi. Front Pharmacol. 2020;11:607287. doi: 10.3389/fphar.2020.607287. eCollection 2020. PubMed PMID: 33569001; PubMed Central PMCID: PMC7868597.
Santamaria AJ, Benavides FD, Saraiva PM, Anderson KD, Khan A, Levi AD, Dietrich WD, Guest JD. Neurophysiological Changes in the First Year After Cell Transplantation in Sub-acute Complete Paraplegia. Front Neurol. 2020;11:514181. doi: 10.3389/fneur.2020.514181. eCollection 2020. PubMed PMID: 33536992; PubMed Central PMCID: PMC7848788.
Bennett C, Álvarez-Ciara A, Franklin M, Dietrich WD, Prasad A. The complement cascade at the Utah microelectrode-tissue interface. Biomaterials. 2021 Jan;268:120583. doi: 10.1016/j.biomaterials.2020.120583. Epub 2020 Dec 7. PubMed PMID: 33310540; PubMed Central PMCID: PMC7856077.
Dietrich WD. The End of a Challenging Year. Ther Hypothermia Temp Manag. 2020 Dec;10(4):191. doi: 10.1089/ther.2020.29077.wdd. Epub 2020 Nov 25. PubMed PMID: 33236956.
de Rivero Vaccari JC, Dietrich WD, Keane RW, de Rivero Vaccari JP. The Inflammasome in Times of COVID-19. Front Immunol. 2020;11:583373. doi: 10.3389/fimmu.2020.583373. eCollection 2020. Review. PubMed PMID: 33149733; PubMed Central PMCID: PMC7580384.
Furlan JC, Liu Y, Dietrich WD 3rd, Norenberg MD, Fehlings MG. Age as a determinant of inflammatory response and survival of glia and axons after human traumatic spinal cord injury. Exp Neurol. 2020 Oct;332:113401. doi: 10.1016/j.expneurol.2020.113401. Epub 2020 Jul 13. PubMed PMID: 32673621.
Dietrich WD. Scientific Advancements During the COVID-19 Pandemic. Ther Hypothermia Temp Manag. 2020 Sep;10(3):130. doi: 10.1089/ther.2020.29075.wdd. Epub 2020 Jul 28. PubMed PMID: 32758079.
Jackson TC, Dietrich WD. Call for Special Issue Papers: A New Way of Thinking About Therapeutic Hypothermia. Ther Hypothermia Temp Manag. 2020 Sep;10(3):129. doi: 10.1089/ther.2020.29074.cfp. Epub 2020 Jun 25. PubMed PMID: 32589553.
Radabaugh HL, Bonnell J, Dietrich WD, Bramlett HM, Schwartz O, Sarkar D. Development and Evaluation of Machine Learning Models for Recovery Prediction after Treatment for Traumatic Brain Injury. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2416-2420. doi: 10.1109/EMBC44109.2020.9175658. PubMed PMID: 33018494.
Scott XO, Stephens ME, Desir MC, Dietrich WD, Keane RW, de Rivero Vaccari JP. The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer's Disease. Int J Mol Sci. 2020 Jun 30;21(13). doi: 10.3390/ijms21134674. PubMed PMID: 32630059; PubMed Central PMCID: PMC7370034.
Dietrich WD. Stay Safe and Healthy. Ther Hypothermia Temp Manag. 2020 Jun;10(2):85. doi: 10.1089/ther.2020.29073.wdd. Epub 2020 May 8. PubMed PMID: 32391723.
Desu HL, Plastini M, Illiano P, Bramlett HM, Dietrich WD, de Rivero Vaccari JP, Brambilla R, Keane RW. IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis. J Neuroinflammation. 2020 May 4;17(1):143. doi: 10.1186/s12974-020-01826-0. PubMed PMID: 32366256; PubMed Central PMCID: PMC7199312.
Dugan EA, Bennett C, Tamames I, Dietrich WD, King CS, Prasad A, Rajguru SM. Therapeutic hypothermia reduces cortical inflammation associated with utah array implants. J Neural Eng. 2020 Apr 29;17(2):026035. doi: 10.1088/1741-2552/ab85d2. PubMed PMID: 32240985; PubMed Central PMCID: PMC8259230.
Dietrich WD. 2020: A New Decade for Therapeutic Hypothermia and Temperature Management. Ther Hypothermia Temp Manag. 2020 Mar;10(1):1. doi: 10.1089/ther.2019.29067.wdd. Epub 2020 Jan 13. PubMed PMID: 31928500.
Blaya M, Truettner J, Zhao W, Bramlett H, Dietrich WD. Mild Hyperthermia Aggravates Glucose Metabolic Consequences in Repetitive Concussion. Int J Mol Sci. 2020 Jan 17;21(2). doi: 10.3390/ijms21020609. PubMed PMID: 31963504; PubMed Central PMCID: PMC7013838.
Kerr N, de Rivero Vaccari JP, Dietrich WD, Keane RW. Neural-respiratory inflammasome axis in traumatic brain injury. Exp Neurol. 2020 Jan;323:113080. doi: 10.1016/j.expneurol.2019.113080. Epub 2019 Oct 15. Review. PubMed PMID: 31626746; PubMed Central PMCID: PMC6981270.
Dietrich WD. December's Wintry Breath. Ther Hypothermia Temp Manag. 2019 Dec;9(4):223. doi: 10.1089/ther.2019.29066.wdd. Epub 2019 Nov 14. PubMed PMID: 31724906.
Perez E, Viziano A, Al-Zaghal Z, Telischi FF, Sangaletti R, Jiang W, Dietrich WD, King C, Hoffer ME, Rajguru SM. Anatomical Correlates and Surgical Considerations for Localized Therapeutic Hypothermia Application in Cochlear Implantation Surgery. Otol Neurotol. 2019 Oct;40(9):1167-1177. doi: 10.1097/MAO.0000000000002373. PubMed PMID: 31318786; PubMed Central PMCID: PMC6750193.
Dietrich WD. Fall Is in the Air. Ther Hypothermia Temp Manag. 2019 Sep;9(3):167. doi: 10.1089/ther.2019.29063.wdd. Epub 2019 Aug 22. PubMed PMID: 31436476.
Dapaah-Siakwan F, Zambrano R, Luo S, Duncan MR, Kerr N, Donda K, de Rivero Vaccari JP, Keane RW, Dietrich WD, Benny M, Young K, Wu S. Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice. Am J Respir Cell Mol Biol. 2019 Sep;61(3):341-354. doi: 10.1165/rcmb.2018-0192OC. PubMed PMID: 30897338.
Dietrich WD. Summer Time for the Journal. Ther Hypothermia Temp Manag. 2019 Jun;9(2):97. doi: 10.1089/ther.2019.29059.wdd. Epub 2019 May 23. PubMed PMID: 31120375.
Burks JD, Gant KL, Guest JD, Jamshidi AG, Cox EM, Anderson KD, Dietrich WD, Bunge MB, Green BA, Khan A, Pearse DD, Saraf-Lavi E, Levi AD. Imaging characteristics of chronic spinal cord injury identified during screening for a cell transplantation clinical trial. Neurosurg Focus. 2019 Mar 1;46(3):E8. doi: 10.3171/2018.12.FOCUS18593. PubMed PMID: 30835682.
Lee SW, de Rivero Vaccari JP, Truettner JS, Dietrich WD, Keane RW. The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury. J Neuroinflammation. 2019 Feb 8;16(1):27. doi: 10.1186/s12974-019-1423-6. PubMed PMID: 30736791; PubMed Central PMCID: PMC6367831.
Blaya MO, Wasserman JM, Pieper AA, Sick TJ, Bramlett HM, Dietrich WD. Neurotherapeutic capacity of P7C3 agents for the treatment of Traumatic Brain Injury. Neuropharmacology. 2019 Feb;145(Pt B):268-282. doi: 10.1016/j.neuropharm.2018.09.024. Epub 2018 Sep 17. Review. PubMed PMID: 30236963; PubMed Central PMCID: PMC6309509.
Santamaría AJ, Benavides FD, DiFede DL, Khan A, Pujol MV, Dietrich WD, Marttos A, Green BA, Hare JM, Guest JD. Clinical and Neurophysiological Changes after Targeted Intrathecal Injections of Bone Marrow Stem Cells in a C3 Tetraplegic Subject. J Neurotrauma. 2019 Feb 1;36(3):500-516. doi: 10.1089/neu.2018.5716. Epub 2018 Jul 23. PubMed PMID: 29790404.
Kerr NA, de Rivero Vaccari JP, Umland O, Bullock MR, Conner GE, Dietrich WD, Keane RW. Human Lung Cell Pyroptosis Following Traumatic Brain Injury. Cells. 2019 Jan 18;8(1). doi: 10.3390/cells8010069. PubMed PMID: 30669285; PubMed Central PMCID: PMC6356886.
Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf JS, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock JT, Tortella FC, Kochanek PM, Wang KKW. Serum-Based Phospho-Neurofilament-Heavy Protein as Theranostic Biomarker in Three Models of Traumatic Brain Injury: An Operation Brain Trauma Therapy Study. J Neurotrauma. 2019 Jan 15;36(2):348-359. doi: 10.1089/neu.2017.5586. Epub 2018 Aug 30. PubMed PMID: 29987972.
Bennett C, Mohammed F, Álvarez-Ciara A, Nguyen MA, Dietrich WD, Rajguru SM, Streit WJ, Prasad A. Neuroinflammation, oxidative stress, and blood-brain barrier (BBB) disruption in acute Utah electrode array implants and the effect of deferoxamine as an iron chelator on acute foreign body response. Biomaterials. 2019 Jan;188:144-159. doi: 10.1016/j.biomaterials.2018.09.040. Epub 2018 Oct 18. PubMed PMID: 30343257; PubMed Central PMCID: PMC6300159.
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