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Huang R, Balu AR, Molitoris KH, White JP, Robling AG, Ayturk UM, Baht GS. The role of Meteorin-like in skeletal development and bone fracture healing. J Orthop Res. 2022 Nov;40(11):2510-2521. doi: 10.1002/jor.25286. Epub 2022 Feb 8. PubMed PMID: 35076116; PubMed Central PMCID: PMC9309188.
Turajane K, Ji G, Chinenov Y, Chao M, Ayturk U, Suhardi VJ, Greenblatt MB, Ivashkiv LB, Bostrom MP, Yang X. RNA-seq Analysis of Peri-Implant Tissue Shows Differences in Immune, Notch, Wnt, and Angiogenesis Pathways in Aged Versus Young Mice. JBMR Plus. 2021 Nov;5(11):e10535. doi: 10.1002/jbm4.10535. eCollection 2021 Nov. PubMed PMID: 34761143; PubMed Central PMCID: PMC8567488.
Spatz JM, Ko FC, Ayturk UM, Warman ML, Bouxsein ML. RNAseq and RNA molecular barcoding reveal differential gene expression in cortical bone following hindlimb unloading in female mice. PLoS One. 2021;16(10):e0250715. doi: 10.1371/journal.pone.0250715. eCollection 2021. PubMed PMID: 34637435; PubMed Central PMCID: PMC8509868.
Xia Y, Sokhi UK, Bell RD, Pannellini T, Turajane K, Niu Y, Frye L, Chao M, Ayturk U, Otero M, Bostrom M, Oliver D, Yang X, Ivashkiv LB. Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice. J Bone Miner Res. 2021 Sep;36(9):1765-1780. doi: 10.1002/jbmr.4381. Epub 2021 Jun 20. PubMed PMID: 34076292; PubMed Central PMCID: PMC8727029.
Vesprey A, Suh ES, Göz Aytürk D, Yang X, Rogers M, Sosa B, Niu Y, Kalajzic I, Ivashkiv LB, Bostrom MP, Ayturk UM. Tmem100- and Acta2-Lineage Cells Contribute to Implant Osseointegration in a Mouse Model. J Bone Miner Res. 2021 May;36(5):1000-1011. doi: 10.1002/jbmr.4264. Epub 2021 Feb 26. PubMed PMID: 33528844; PubMed Central PMCID: PMC8715516.
Ayturk UM, Scollan JP, Goz Ayturk D, Suh ES, Vesprey A, Jacobsen CM, Divieti Pajevic P, Warman ML. Single-Cell RNA Sequencing of Calvarial and Long-Bone Endocortical Cells. J Bone Miner Res. 2020 Oct;35(10):1981-1991. doi: 10.1002/jbmr.4052. Epub 2020 Jul 20. PubMed PMID: 32427356; PubMed Central PMCID: PMC8265023.
Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim KE, Droscha CJ, Madaj ZB, Foxa GE, Izaguirre I, Robling AG, Warman ML, Williams BO. Independent validation of experimental results requires timely and unrestricted access to animal models and reagents. PLoS Genet. 2020 Jun;16(6):e1008940. doi: 10.1371/journal.pgen.1008940. eCollection 2020 Jun. PubMed PMID: 32589665; PubMed Central PMCID: PMC7319330.
Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim KE, Droscha CJ, Madaj ZB, Foxa GE, Izaguirre I, Transgenics Core VVA, Paracha N, Pidhaynyy B, Dowd TL, Robling AG, Warman ML, Williams BO. An osteocalcin-deficient mouse strain without endocrine abnormalities. PLoS Genet. 2020 May;16(5):e1008361. doi: 10.1371/journal.pgen.1008361. eCollection 2020 May. PubMed PMID: 32463812; PubMed Central PMCID: PMC7255615.
Ayturk UM, Sieker JT, Haslauer CM, Proffen BL, Weissenberger MH, Warman ML, Fleming BC, Murray MM. Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis. PLoS One. 2020;15(2):e0229449. doi: 10.1371/journal.pone.0229449. eCollection 2020. PubMed PMID: 32107493; PubMed Central PMCID: PMC7046188.
Nishimori S, O'Meara MJ, Castro CD, Noda H, Cetinbas M, da Silva Martins J, Ayturk U, Brooks DJ, Bruce M, Nagata M, Ono W, Janton CJ, Bouxsein ML, Foretz M, Berdeaux R, Sadreyev RI, Gardella TJ, Jüppner H, Kronenberg HM, Wein MN. Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling. J Clin Invest. 2019 Dec 2;129(12):5187-5203. doi: 10.1172/JCI130126. PubMed PMID: 31430259; PubMed Central PMCID: PMC6877304.
Ayturk U. RNA-seq in Skeletal Biology. Curr Osteoporos Rep. 2019 Aug;17(4):178-185. doi: 10.1007/s11914-019-00517-x. Review. PubMed PMID: 31093870.
Greenblatt MB, Ono N, Ayturk UM, Debnath S, Lalani S. The Unmixing Problem: A Guide to Applying Single-Cell RNA Sequencing to Bone. J Bone Miner Res. 2019 Jul;34(7):1207-1219. doi: 10.1002/jbmr.3802. Review. PubMed PMID: 31336008; PubMed Central PMCID: PMC6658136.
Grigelioniene G, Suzuki HI, Taylan F, Mirzamohammadi F, Borochowitz ZU, Ayturk UM, Tzur S, Horemuzova E, Lindstrand A, Weis MA, Grigelionis G, Hammarsjö A, Marsk E, Nordgren A, Nordenskjöld M, Eyre DR, Warman ML, Nishimura G, Sharp PA, Kobayashi T. Gain-of-function mutation of microRNA-140 in human skeletal dysplasia. Nat Med. 2019 Apr;25(4):583-590. doi: 10.1038/s41591-019-0353-2. Epub 2019 Feb 25. PubMed PMID: 30804514; PubMed Central PMCID: PMC6622181.
Mirzamohammadi F, Kozlova A, Papaioannou G, Paltrinieri E, Ayturk UM, Kobayashi T. Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. Nat Commun. 2018 Apr 10;9(1):1352. doi: 10.1038/s41467-018-03788-7. PubMed PMID: 29636449; PubMed Central PMCID: PMC5893605.
Tafaj O, Hann S, Ayturk U, Warman ML, Jüppner H. Mice maintain predominantly maternal Gαs expression throughout life in brown fat tissue (BAT), but not other tissues. Bone. 2017 Oct;103:177-187. doi: 10.1016/j.bone.2017.07.001. Epub 2017 Jul 8. PubMed PMID: 28694163; PubMed Central PMCID: PMC5943706.
Couto JA, Ayturk UM, Konczyk DJ, Goss JA, Huang AY, Hann S, Reeve JL, Liang MG, Bischoff J, Warman ML, Greene AK. A somatic GNA11 mutation is associated with extremity capillary malformation and overgrowth. Angiogenesis. 2017 Aug;20(3):303-306. doi: 10.1007/s10456-016-9538-1. Epub 2017 Jan 24. PubMed PMID: 28120216; PubMed Central PMCID: PMC5511772.
Sieker JT, Ayturk UM, Proffen BL, Weissenberger MH, Kiapour AM, Murray MM. Immediate Administration of Intraarticular Triamcinolone Acetonide After Joint Injury Modulates Molecular Outcomes Associated With Early Synovitis. Arthritis Rheumatol. 2016 Jul;68(7):1637-47. doi: 10.1002/art.39631. PubMed PMID: 26866935; PubMed Central PMCID: PMC4982368.
Ayturk UM, Couto JA, Hann S, Mulliken JB, Williams KL, Huang AY, Fishman SJ, Boyd TK, Kozakewich HP, Bischoff J, Greene AK, Warman ML. Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma. Am J Hum Genet. 2016 Apr 7;98(4):789-95. doi: 10.1016/j.ajhg.2016.03.009. PubMed PMID: 27058448; PubMed Central PMCID: PMC4833432.
Hill A, Waller KA, Cui Y, Allen JM, Smits P, Zhang LX, Ayturk UM, Hann S, Lessard SG, Zurakowski D, Warman ML, Jay GD. Lubricin restoration in a mouse model of congenital deficiency. Arthritis Rheumatol. 2015 Nov;67(11):3070-81. doi: 10.1002/art.39276. PubMed PMID: 26216721; PubMed Central PMCID: PMC4626303.
Kozhemyakina E, Zhang M, Ionescu A, Ayturk UM, Ono N, Kobayashi A, Kronenberg H, Warman ML, Lassar AB. Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. Arthritis Rheumatol. 2015 May;67(5):1261-73. doi: 10.1002/art.39030. PubMed PMID: 25603997; PubMed Central PMCID: PMC4414823.
Bennike T, Ayturk U, Haslauer CM, Froehlich JW, Proffen BL, Barnaby O, Birkelund S, Murray MM, Warman ML, Stensballe A, Steen H. A normative study of the synovial fluid proteome from healthy porcine knee joints. J Proteome Res. 2014 Oct 3;13(10):4377-87. doi: 10.1021/pr500587x. Epub 2014 Sep 3. PubMed PMID: 25160569; PubMed Central PMCID: PMC4184458.
Jacobsen CM, Barber LA, Ayturk UM, Roberts HJ, Deal LE, Schwartz MA, Weis M, Eyre D, Zurakowski D, Robling AG, Warman ML. Targeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta. J Bone Miner Res. 2014 Oct;29(10):2297-306. doi: 10.1002/jbmr.2198. PubMed PMID: 24677211; PubMed Central PMCID: PMC4130796.
Bowen ME, Ayturk UM, Kurek KC, Yang W, Warman ML. SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates. PLoS Genet. 2014;10(5):e1004364. doi: 10.1371/journal.pgen.1004364. eCollection 2014. PubMed PMID: 24875294; PubMed Central PMCID: PMC4038465.
Kedlaya R, Veera S, Horan DJ, Moss RE, Ayturk UM, Jacobsen CM, Bowen ME, Paszty C, Warman ML, Robling AG. Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome. Sci Transl Med. 2013 Nov 13;5(211):211ra158. doi: 10.1126/scitranslmed.3006627. PubMed PMID: 24225945; PubMed Central PMCID: PMC3964772.
Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML. An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations. J Bone Miner Res. 2013 Oct;28(10):2081-93. doi: 10.1002/jbmr.1946. PubMed PMID: 23553928; PubMed Central PMCID: PMC3743099.
Ayturk UM, Gadomski B, Schuldt D, Patel V, Puttlitz CM. Modeling degenerative disk disease in the lumbar spine: a combined experimental, constitutive, and computational approach. J Biomech Eng. 2012 Oct;134(10):101003. doi: 10.1115/1.4007632. PubMed PMID: 23083194.
Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Bowen ME, Yamamoto GL, Kozakewich HP, Warman ML. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet. 2012 Jun 8;90(6):1108-15. doi: 10.1016/j.ajhg.2012.05.006. Epub 2012 May 31. PubMed PMID: 22658544; PubMed Central PMCID: PMC3370283.
Ayturk UM, Puttlitz CM. Parametric convergence sensitivity and validation of a finite element model of the human lumbar spine. Comput Methods Biomech Biomed Engin. 2011 Aug;14(8):695-705. doi: 10.1080/10255842.2010.493517. Epub 2011 May 24. PubMed PMID: 21229413.
Womack W, Ayturk UM, Puttlitz CM. Cartilage thickness distribution affects computational model predictions of cervical spine facet contact parameters. J Biomech Eng. 2011 Jan;133(1):011009. doi: 10.1115/1.4002855. PubMed PMID: 21186899.
Ayturk UM, Garcia JJ, Puttlitz CM. The micromechanical role of the annulus fibrosus components under physiological loading of the lumbar spine. J Biomech Eng. 2010 Jun;132(6):061007. doi: 10.1115/1.4001032. PubMed PMID: 20887032.
Haussler KK, McGilvray KC, Ayturk UM, Puttlitz CM, Hills AE, McIlwraith CW. Deformation of the equine pelvis in response to in vitro 3D sacroiliac joint loading. Equine Vet J. 2009 Mar;41(3):207-12. doi: 10.2746/042516409x395697. PubMed PMID: 19469222.
Kim T, Ayturk UM, Haskell A, Miclau T, Puttlitz CM. Fixation of osteoporotic distal fibula fractures: A biomechanical comparison of locking versus conventional plates. J Foot Ankle Surg. 2007 Jan-Feb;46(1):2-6. doi: 10.1053/j.jfas.2006.09.009. PubMed PMID: 17198946.
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