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Sunad Rangarajan's Bibliography

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Rangarajan S, Locy ML, Chanda D, Kurundkar A, Kurundkar D, Larson-Casey JL, Londono P, Bagchi RA, Deskin B, Elajaili H, Nozik ES, Deshane JS, Zmijewski JW, Eickelberg O, Thannickal VJ. Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis. Aging Cell. 2022 Sep;21(9):e13674. doi: 10.1111/acel.13674. Epub 2022 Aug 7. PubMed PMID: 35934931; PubMed Central PMCID: PMC9470902.

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Rehan M, Kurundkar D, Kurundkar AR, Logsdon NJ, Smith SR, Chanda D, Bernard K, Sanders YY, Deshane JS, Dsouza KG, Rangarajan S, Zmijewski JW, Thannickal VJ. Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice. Nat Aging. 2021 Feb;1(2):205-217. doi: 10.1038/s43587-021-00027-5. Epub 2021 Feb 11. PubMed PMID: 34386777; PubMed Central PMCID: PMC8357317.

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Locy ML, Rangarajan S, Yang S, Johnson MR, Bernard K, Kurundkar A, Bone NB, Zmijewski JW, Byun J, Pennathur S, Zhou Y, Thannickal VJ. Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration. Sci Signal. 2020 Aug 11;13(644). doi: 10.1126/scisignal.aau2803. PubMed PMID: 32788339; PubMed Central PMCID: PMC9394744.

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Rangarajan S, Thannickal VJ. Remember Me? The Bone Marrow in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 Oct 15;200(8):959-960. doi: 10.1164/rccm.201906-1101ED. PubMed PMID: 31206314; PubMed Central PMCID: PMC6794115.

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Rangarajan S, Bone NB, Zmijewska AA, Jiang S, Park DW, Bernard K, Locy ML, Ravi S, Deshane J, Mannon RB, Abraham E, Darley-Usmar V, Thannickal VJ, Zmijewski JW. Metformin reverses established lung fibrosis in a bleomycin model. Nat Med. 2018 Aug;24(8):1121-1127. doi: 10.1038/s41591-018-0087-6. Epub 2018 Jul 2. PubMed PMID: 29967351; PubMed Central PMCID: PMC6081262.

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Rangarajan S, Lee JS. The TAMing of the Idiopathic Pulmonary Fibrosis Myofibroblast. One Step Closer?. Am J Respir Crit Care Med. 2018 Jun 1;197(11):1377-1378. doi: 10.1164/rccm.201802-0222ED. PubMed PMID: 29664671.

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Rangarajan S, Bernard K, Thannickal VJ. Mitochondrial Dysfunction in Pulmonary Fibrosis. Ann Am Thorac Soc. 2017 Nov;14(Supplement_5):S383-S388. doi: 10.1513/AnnalsATS.201705-370AW. Review. PubMed PMID: 29161077; PubMed Central PMCID: PMC5711275.

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Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E, Zhang K, Kumar R, Rangarajan S, Eipers P, Wang Y, Srivastava RK, Rodriguez Dager JV, Athar M, Morrow C, Hoopes CW, Chaplin DD, Thannickal VJ, Deshane JS. Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients. J Heart Lung Transplant. 2017 Jul 15;. doi: 10.1016/j.healun.2017.07.007. [Epub ahead of print] PubMed PMID: 28756121; PubMed Central PMCID: PMC5893420.

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Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB. 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs. JCI Insight. 2017 Apr 20;2(8). doi: 10.1172/jci.insight.94088. eCollection 2017 Apr 20. PubMed PMID: 28422764; PubMed Central PMCID: PMC5396517.

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Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB. 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs. JCI Insight. 2017 Jan 26;2(2):e91377. doi: 10.1172/jci.insight.91377. PubMed PMID: 28138565; PubMed Central PMCID: PMC5256136.

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Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma NS, Logsdon NJ, Liu H, Crossman DK, Horowitz JC, De Langhe S, Thannickal VJ. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Sci Rep. 2016 Nov 21;6:37445. doi: 10.1038/srep37445. PubMed PMID: 27869174; PubMed Central PMCID: PMC5116673.

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Kurundkar AR, Kurundkar D, Rangarajan S, Locy ML, Zhou Y, Liu RM, Zmijewski J, Thannickal VJ. The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury. FASEB J. 2016 Jun;30(6):2135-50. doi: 10.1096/fj.201500173. Epub 2016 Feb 16. PubMed PMID: 26884454; PubMed Central PMCID: PMC4871800.

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Rangarajan S, Locy ML, Luckhardt TR, Thannickal VJ. Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?. Drugs. 2016 Mar;76(3):291-300. doi: 10.1007/s40265-015-0523-6. Review. PubMed PMID: 26729185; PubMed Central PMCID: PMC4939080.

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Rangarajan S, Kurundkar A, Kurundkar D, Bernard K, Sanders YY, Ding Q, Antony VB, Zhang J, Zmijewski J, Thannickal VJ. Novel Mechanisms for the Antifibrotic Action of Nintedanib. Am J Respir Cell Mol Biol. 2016 Jan;54(1):51-9. doi: 10.1165/rcmb.2014-0445OC. PubMed PMID: 26072676; PubMed Central PMCID: PMC4742925.

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Bernard K, Logsdon NJ, Ravi S, Xie N, Persons BP, Rangarajan S, Zmijewski JW, Mitra K, Liu G, Darley-Usmar VM, Thannickal VJ. Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation. J Biol Chem. 2015 Oct 16;290(42):25427-38. doi: 10.1074/jbc.M115.646984. Epub 2015 Aug 28. PubMed PMID: 26318453; PubMed Central PMCID: PMC4646190.

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Sanders YY, Cui Z, Le Saux CJ, Horowitz JC, Rangarajan S, Kurundkar A, Antony VB, Thannickal VJ. SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts. PLoS One. 2015;10(2):e0116995. doi: 10.1371/journal.pone.0116995. eCollection 2015. PubMed PMID: 25658089; PubMed Central PMCID: PMC4319960.

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Rangarajan S, Rangarajan S, D'Souza GA. Restless legs syndrome in an Indian urban population. Sleep Med. 2007 Dec;9(1):88-93. doi: 10.1016/j.sleep.2006.11.004. Epub 2007 Sep 6. PubMed PMID: 17825618.

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Rangarajan S, D'Souza GA. Restless legs syndrome in Indian patients having iron deficiency anemia in a tertiary care hospital. Sleep Med. 2007 Apr;8(3):247-51. doi: 10.1016/j.sleep.2006.10.004. Epub 2007 Mar 26. PubMed PMID: 17368978.

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