My Bibliography

select

Richter MJR, Zécri FJ, Briner K, Schreiber SL. Modular Synthesis of Cyclopropane-Fused N-Heterocycles Enabled by Underexplored Diazo Reagents. Angew Chem Int Ed Engl. 2022 Apr 8;:e202203221. doi: 10.1002/anie.202203221. [Epub ahead of print] PubMed PMID: 35395129; NIHMSID:NIHMS1797724.

select

Rodriguez R, Schreiber SL, Conrad M. Persister cancer cells: Iron addiction and vulnerability to ferroptosis. Mol Cell. 2022 Feb 17;82(4):728-740. doi: 10.1016/j.molcel.2021.12.001. Epub 2021 Dec 28. Review. PubMed PMID: 34965379; PubMed Central PMCID: PMC9152905.

select

Radke JB, Melillo B, Mittal P, Sharma M, Sharma A, Fu Y, Uddin T, Gonse A, Comer E, Schreiber SL, Gupta AK, Chatterjee AK, Sibley LD. Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase. Nat Commun. 2022 Jan 24;13(1):459. doi: 10.1038/s41467-022-28108-y. PubMed PMID: 35075105; PubMed Central PMCID: PMC8786932.

select

Wang F, Graham ET, Naowarojna N, Shi Z, Wang Y, Xie G, Zhou L, Salmon W, Jia JM, Wang X, Huang Y, Schreiber SL, Zou Y. PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ. Cell Chem Biol. 2022 Jan 20;29(1):157-170.e6. doi: 10.1016/j.chembiol.2021.11.001. Epub 2021 Nov 22. PubMed PMID: 34813762; PubMed Central PMCID: PMC8792350.

select

Bortot LO, Rangel VL, Pavlovici FA, El Omari K, Wagner A, Brandao-Neto J, Talon R, von Delft F, Reidenbach AG, Vallabh SM, Minikel EV, Schreiber S, Nonato MC. Novel quaternary structures of the human prion protein globular domain. Biochimie. 2021 Dec;191:118-125. doi: 10.1016/j.biochi.2021.09.005. Epub 2021 Sep 10. PubMed PMID: 34517052; PubMed Central PMCID: PMC8627497.

select

Negi V, Yang J, Speyer G, Pulgarin A, Handen A, Zhao J, Tai YY, Tang Y, Culley MK, Yu Q, Forsythe P, Gorelova A, Watson AM, Al Aaraj Y, Satoh T, Sharifi-Sanjani M, Rajaratnam A, Sembrat J, Provencher S, Yin X, Vargas SO, Rojas M, Bonnet S, Torrino S, Wagner BK, Schreiber SL, Dai M, Bertero T, Al Ghouleh I, Kim S, Chan SY. Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. Sci Adv. 2021 Oct 22;7(43):eabh3794. doi: 10.1126/sciadv.abh3794. Epub 2021 Oct 20. PubMed PMID: 34669463; PubMed Central PMCID: PMC8528428.

select

Clemons PA, Bittker JA, Wagner FF, Hands A, Dančík V, Schreiber SL, Choudhary A, Wagner BK. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. SLAS Discov. 2021 Aug;26(7):855-861. doi: 10.1177/24725552211019410. Epub 2021 Jun 16. PubMed PMID: 34130532; PubMed Central PMCID: PMC8991386.

select

Rossmann MP, Hoi K, Chan V, Abraham BJ, Yang S, Mullahoo J, Papanastasiou M, Wang Y, Elia I, Perlin JR, Hagedorn EJ, Hetzel S, Weigert R, Vyas S, Nag PP, Sullivan LB, Warren CR, Dorjsuren B, Greig EC, Adatto I, Cowan CA, Schreiber SL, Young RA, Meissner A, Haigis MC, Hekimi S, Carr SA, Zon LI. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science. 2021 May 14;372(6543):716-721. doi: 10.1126/science.aaz2740. PubMed PMID: 33986176; PubMed Central PMCID: PMC8177078.

select

Zou Y, Li H, Graham ET, Deik AA, Eaton JK, Wang W, Sandoval-Gomez G, Clish CB, Doench JG, Schreiber SL. Author Correction: Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis. Nat Chem Biol. 2021 Apr;17(4):501. doi: 10.1038/s41589-021-00767-w. PubMed PMID: 33654315.

select

Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS. An expanded universe of cancer targets. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Review. PubMed PMID: 33667368; PubMed Central PMCID: PMC8066437.

select

Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ, Schreiber SL, MacArthur DG. Author Correction: Evaluating drug targets through human loss-of-function genetic variation. Nature. 2021 Feb;590(7846):E56. doi: 10.1038/s41586-020-03177-5. PubMed PMID: 33536628; PubMed Central PMCID: PMC8064910.

select

Moosmayer D, Hilpmann A, Hoffmann J, Schnirch L, Zimmermann K, Badock V, Furst L, Eaton JK, Viswanathan VS, Schreiber SL, Gradl S, Hillig RC. Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta Crystallogr D Struct Biol. 2021 Feb 1;77(Pt 2):237-248. doi: 10.1107/S2059798320016125. Epub 2021 Jan 26. PubMed PMID: 33559612; PubMed Central PMCID: PMC7869902.

select

Sheppard HE, Dall'Agnese A, Park WD, Shamim MH, Dubrulle J, Johnson HL, Stossi F, Cogswell P, Sommer J, Levy J, Sharifnia T, Wawer MJ, Nabet B, Gray NS, Clemons PA, Schreiber SL, Workman P, Young RA, Lin CY. Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity. Cell Rep Med. 2021 Jan 19;2(1):100188. doi: 10.1016/j.xcrm.2020.100188. eCollection 2021 Jan 19. PubMed PMID: 33521702; PubMed Central PMCID: PMC7817874.

select

Sharma M, Malhotra N, Yogavel M, Harlos K, Melillo B, Comer E, Gonse A, Parvez S, Mitasev B, Fang FG, Schreiber SL, Sharma A. Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines. Nat Commun. 2021 Jan 12;12(1):343. doi: 10.1038/s41467-020-20478-5. PubMed PMID: 33436639; PubMed Central PMCID: PMC7803973.

select

Schreiber SL. The Rise of Molecular Glues. Cell. 2021 Jan 7;184(1):3-9. doi: 10.1016/j.cell.2020.12.020. PubMed PMID: 33417864.

select

Eaton JK, Furst L, Cai LL, Viswanathan VS, Schreiber SL. Structure-activity relationships of GPX4 inhibitor warheads. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127538. doi: 10.1016/j.bmcl.2020.127538. Epub 2020 Sep 11. PubMed PMID: 32920142; PubMed Central PMCID: PMC8006158.

select

Minikel EV, Zhao HT, Le J, O'Moore J, Pitstick R, Graffam S, Carlson GA, Kavanaugh MP, Kriz J, Kim JB, Ma J, Wille H, Aiken J, McKenzie D, Doh-Ura K, Beck M, O'Keefe R, Stathopoulos J, Caron T, Schreiber SL, Carroll JB, Kordasiewicz HB, Cabin DE, Vallabh SM. Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints. Nucleic Acids Res. 2020 Nov 4;48(19):10615-10631. doi: 10.1093/nar/gkaa616. PubMed PMID: 32776089; PubMed Central PMCID: PMC7641729.

select

Vinayak S, Jumani RS, Miller P, Hasan MM, McLeod BI, Tandel J, Stebbins EE, Teixeira JE, Borrel J, Gonse A, Zhang M, Yu X, Wernimont A, Walpole C, Eckley S, Love MS, McNamara CW, Sharma M, Sharma A, Scherer CA, Kato N, Schreiber SL, Melillo B, Striepen B, Huston CD, Comer E. Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase. Sci Transl Med. 2020 Sep 30;12(563). doi: 10.1126/scitranslmed.aba8412. PubMed PMID: 32998973; PubMed Central PMCID: PMC8381743.

select

Reidenbach AG, Mesleh MF, Casalena D, Vallabh SM, Dahlin JL, Leed AJ, Chan AI, Usanov DL, Yehl JB, Lemke CT, Campbell AJ, Shah RN, Shrestha OK, Sacher JR, Rangel VL, Moroco JA, Sathappa M, Nonato MC, Nguyen KT, Wright SK, Liu DR, Wagner FF, Kaushik VK, Auld DS, Schreiber SL, Minikel EV. Multimodal small-molecule screening for human prion protein binders. J Biol Chem. 2020 Sep 25;295(39):13516-13531. doi: 10.1074/jbc.RA120.014905. Epub 2020 Jul 28. PubMed PMID: 32723867; PubMed Central PMCID: PMC7521658.

select

Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt F, Eaton JK, Ferguson B, Wang W, Fairman J, Keys HR, Dančík V, Clish CB, Clemons PA, Hammond PT, Boyer LA, Weinberg RA, Schreiber SL. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Nature. 2020 Sep;585(7826):603-608. doi: 10.1038/s41586-020-2732-8. Epub 2020 Sep 16. PubMed PMID: 32939090; PubMed Central PMCID: PMC8051864.

select

Howard TP, Oberlick EM, Rees MG, Arnoff TE, Pham MT, Brenan L, DoCarmo M, Hong AL, Kugener G, Chou HC, Drosos Y, Mathias KM, Ramos P, Seashore-Ludlow B, Giacomelli AO, Wang X, Freeman BB 3rd, Blankenship K, Hoffmann L, Tiv HL, Gokhale PC, Johannessen CM, Stewart EA, Schreiber SL, Hahn WC, Roberts CWM. Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine. Clin Cancer Res. 2020 Sep 15;26(18):4995-5006. doi: 10.1158/1078-0432.CCR-19-2717. Epub 2020 Jul 6. PubMed PMID: 32631955; PubMed Central PMCID: PMC7501142.

select

Yusuf RZ, Saez B, Sharda A, van Gastel N, Yu VWC, Baryawno N, Scadden EW, Acharya S, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, Das S, Hutchinson JN, Churchill M, Mukherjee S, Lee D, Mercier F, Doench J, Bullinger L, Logan DJ, Schreiber S, Stephanopoulos G, Rizzo WB, Scadden DT. Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers. Blood. 2020 Sep 10;136(11):1303-1316. doi: 10.1182/blood.2019001808. PubMed PMID: 32458004; PubMed Central PMCID: PMC7483435.

select

Vinogradova EV, Zhang X, Remillard D, Lazar DC, Suciu RM, Wang Y, Bianco G, Yamashita Y, Crowley VM, Schafroth MA, Yokoyama M, Konrad DB, Lum KM, Simon GM, Kemper EK, Lazear MR, Yin S, Blewett MM, Dix MM, Nguyen N, Shokhirev MN, Chin EN, Lairson LL, Melillo B, Schreiber SL, Forli S, Teijaro JR, Cravatt BF. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29. PubMed PMID: 32730809; PubMed Central PMCID: PMC7775622.

select

Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Phosphorylation-Inducing Chimeric Small Molecules. J Am Chem Soc. 2020 Aug 19;142(33):14052-14057. doi: 10.1021/jacs.0c05537. Epub 2020 Aug 4. PubMed PMID: 32787262.

select

Gerry CJ, Schreiber SL. Recent achievements and current trajectories of diversity-oriented synthesis. Curr Opin Chem Biol. 2020 Jun;56:1-9. doi: 10.1016/j.cbpa.2019.08.008. Epub 2019 Oct 15. Review. PubMed PMID: 31622927.

select

Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ, Schreiber SL, MacArthur DG. Evaluating drug targets through human loss-of-function genetic variation. Nature. 2020 May;581(7809):459-464. doi: 10.1038/s41586-020-2267-z. Epub 2020 May 27. PubMed PMID: 32461653; PubMed Central PMCID: PMC7272226.

select

Xia G, Zhuang Z, Liu LY, Schreiber SL, Melillo B, Yu JQ. Ligand-Enabled β-Methylene C(sp³ )-H Arylation of Masked Aliphatic Alcohols. Angew Chem Int Ed Engl. 2020 May 11;59(20):7783-7787. doi: 10.1002/anie.202000632. Epub 2020 Mar 11. PubMed PMID: 32050036; PubMed Central PMCID: PMC7219561.

select

Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, Zimmermann K, Cai LL, Niehues M, Badock V, Kramm A, Chen S, Hillig RC, Clemons PA, Gradl S, Montagnon C, Lazarski KE, Christian S, Bajrami B, Neuhaus R, Eheim AL, Viswanathan VS, Schreiber SL. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nat Chem Biol. 2020 May;16(5):497-506. doi: 10.1038/s41589-020-0501-5. Epub 2020 Mar 30. PubMed PMID: 32231343; PubMed Central PMCID: PMC7251976.

select

Westphal MV, Hudson L, Mason JW, Pradeilles JA, Zécri FJ, Briner K, Schreiber SL. Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis. J Am Chem Soc. 2020 Apr 29;142(17):7776-7782. doi: 10.1021/jacs.9b13186. Epub 2020 Apr 16. PubMed PMID: 32267148; PubMed Central PMCID: PMC7294439.

select

Zou Y, Schreiber SL. Progress in Understanding Ferroptosis and Challenges in Its Targeting for Therapeutic Benefit. Cell Chem Biol. 2020 Apr 16;27(4):463-471. doi: 10.1016/j.chembiol.2020.03.015. Review. PubMed PMID: 32302583; PubMed Central PMCID: PMC7346472.

select

Zou Y, Graham ET, Huang Y, Salmon W, Yu L, Schreiber SL. PALP: An imaging method for detecting and quantifying polyunsaturated phospholipids via peroxidation. [preprint]. 2020 April. Available from: https://doi.org/10.1101/2020.04.11.037218.

select

Vallabh SM, Minikel EV, Schreiber SL, Lander ES. Towards a treatment for genetic prion disease: trials and biomarkers. Lancet Neurol. 2020 Apr;19(4):361-368. doi: 10.1016/S1474-4422(19)30403-X. Epub 2020 Mar 18. Review. PubMed PMID: 32199098.

select

Gerry CJ, Schreiber SL. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378. doi: 10.1038/s41589-020-0469-1. Epub 2020 Mar 20. Review. PubMed PMID: 32198490; PubMed Central PMCID: PMC7312755.

select

Miller PG, Niroula A, Ceremsak JJ, Gibson CJ, Taylor MS, Birndt S, Perner F, Arnason J, Sperling AS, Agrawal M, Schram AM, Nikiforow S, Pihan G, Hasserjian RP, Aster JC, La Rosée P, Morgan EA, Berliner N, Ebert BL. Identification of germline variants in adults with hemophagocytic lymphohistiocytosis. Blood Adv. 2020 Mar 10;4(5):925-929. doi: 10.1182/bloodadvances.2019001272. PubMed PMID: 32150605; PubMed Central PMCID: PMC7065469.

select

Zou Y, Li H, Graham ET, Deik AA, Eaton JK, Wang W, Sandoval-Gomez G, Clish CB, Doench JG, Schreiber SL. Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis. Nat Chem Biol. 2020 Mar;16(3):302-309. doi: 10.1038/s41589-020-0472-6. Epub 2020 Feb 17. PubMed PMID: 32080622; PubMed Central PMCID: PMC7353921.

select

Michalska K, Chang C, Maltseva NI, Jedrzejczak R, Robertson GT, Gusovsky F, McCarren P, Schreiber SL, Nag PP, Joachimiak A. Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase. Protein Sci. 2020 Mar;29(3):779-788. doi: 10.1002/pro.3825. Epub 2020 Jan 20. PubMed PMID: 31930594; PubMed Central PMCID: PMC7020977.

select

Eaton JK, Ruberto RA, Kramm A, Viswanathan VS, Schreiber SL. Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently. J Am Chem Soc. 2019 Dec 26;141(51):20407-20415. doi: 10.1021/jacs.9b10769. Epub 2019 Dec 16. PubMed PMID: 31841309.

select

Reidenbach AG, Minikel EV, Zhao HT, Guzman SG, Leed AJ, Mesleh MF, Kordasiewicz HB, Schreiber SL, Vallabh SM. Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides. Biomolecules. 2019 Dec 18;10(1). doi: 10.3390/biom10010001. PubMed PMID: 31861275; PubMed Central PMCID: PMC7022474.

select

Minikel EV, Kuhn E, Cocco AR, Vallabh SM, Hartigan CR, Reidenbach AG, Safar JG, Raymond GJ, McCarthy MD, O'Keefe R, Llorens F, Zerr I, Capellari S, Parchi P, Schreiber SL, Carr SA. Domain-specific Quantification of Prion Protein in Cerebrospinal Fluid by Targeted Mass Spectrometry. Mol Cell Proteomics. 2019 Dec;18(12):2388-2400. doi: 10.1074/mcp.RA119.001702. Epub 2019 Sep 26. PubMed PMID: 31558565; PubMed Central PMCID: PMC6885701.

select

Lewis TA, de Waal L, Wu X, Youngsaye W, Wengner A, Kopitz C, Lange M, Gradl S, Ellermann M, Lienau P, Schreiber SL, Greulich H, Meyerson M. Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. ACS Med Chem Lett. 2019 Nov 14;10(11):1537-1542. doi: 10.1021/acsmedchemlett.9b00360. eCollection 2019 Nov 14. PubMed PMID: 31749907; PubMed Central PMCID: PMC6862344.

select

To TL, Cuadros AM, Shah H, Hung WHW, Li Y, Kim SH, Rubin DHF, Boe RH, Rath S, Eaton JK, Piccioni F, Goodale A, Kalani Z, Doench JG, Root DE, Schreiber SL, Vafai SB, Mootha VK. A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering. Cell. 2019 Nov 14;179(5):1222-1238.e17. doi: 10.1016/j.cell.2019.10.032. PubMed PMID: 31730859; PubMed Central PMCID: PMC7053407.

select

Holtzman SH, Cohen R, Levin JM, Maraganore J. Chinese scientists and US leadership in the life sciences. Nat Biotechnol. 2019 Nov;37(11):1261-1263. doi: 10.1038/s41587-019-0285-x. PubMed PMID: 31582856.

select

Li H, Bullock K, Gurjao C, Braun D, Shukla SA, Bossé D, Lalani AA, Gopal S, Jin C, Horak C, Wind-Rotolo M, Signoretti S, McDermott DF, Freeman GJ, Van Allen EM, Schreiber SL, Stephen Hodi F, Sellers WR, Garraway LA, Clish CB, Choueiri TK, Giannakis M. Metabolomic adaptations and correlates of survival to immune checkpoint blockade. Nat Commun. 2019 Sep 25;10(1):4346. doi: 10.1038/s41467-019-12361-9. PubMed PMID: 31554815; PubMed Central PMCID: PMC6761178.

select

Li H, Ericsson M, Rabasha B, Budnik B, Chan SH, Freinkman E, Lewis CA, Doench JG, Wagner BK, Garraway LA, Schreiber SL. 6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels. Cell Chem Biol. 2019 Sep 19;26(9):1306-1314.e5. doi: 10.1016/j.chembiol.2019.05.006. Epub 2019 Jun 13. PubMed PMID: 31204288; PubMed Central PMCID: PMC6754299.

select

Oberlick EM, Rees MG, Seashore-Ludlow B, Vazquez F, Nelson GM, Dharia NV, Weir BA, Tsherniak A, Ghandi M, Krill-Burger JM, Meyers RM, Wang X, Montgomery P, Root DE, Bieber JM, Radko S, Cheah JH, Hon CS, Shamji AF, Clemons PA, Park PJ, Dyer MA, Golub TR, Stegmaier K, Hahn WC, Stewart EA, Schreiber SL, Roberts CWM. Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors. Cell Rep. 2019 Aug 27;28(9):2331-2344.e8. doi: 10.1016/j.celrep.2019.07.021. PubMed PMID: 31461650; PubMed Central PMCID: PMC7319190.

select

Boettcher S, Miller PG, Sharma R, McConkey M, Leventhal M, Krivtsov AV, Giacomelli AO, Wong W, Kim J, Chao S, Kurppa KJ, Yang X, Milenkowic K, Piccioni F, Root DE, Rücker FG, Flamand Y, Neuberg D, Lindsley RC, Jänne PA, Hahn WC, Jacks T, Döhner H, Armstrong SA, Ebert BL. A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science. 2019 Aug 9;365(6453):599-604. doi: 10.1126/science.aax3649. PubMed PMID: 31395785; PubMed Central PMCID: PMC7327437.

select

Raymond GJ, Zhao HT, Race B, Raymond LD, Williams K, Swayze EE, Graffam S, Le J, Caron T, Stathopoulos J, O'Keefe R, Lubke LL, Reidenbach AG, Kraus A, Schreiber SL, Mazur C, Cabin DE, Carroll JB, Minikel EV, Kordasiewicz H, Caughey B, Vallabh SM. Antisense oligonucleotides extend survival of prion-infected mice. JCI Insight. 2019 Jul 30;5. doi: 10.1172/jci.insight.131175. PubMed PMID: 31361599; PubMed Central PMCID: PMC6777807.

select

Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, Słabicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, Fulciniti M, Udeshi ND, Kuhn E, Letai A, Munshi NC, Carr SA, Ebert BL. Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs. Blood. 2019 Jul 11;134(2):160-170. doi: 10.1182/blood.2019000789. Epub 2019 May 1. PubMed PMID: 31043423; PubMed Central PMCID: PMC6624968.

select

Gerry CJ, Wawer MJ, Clemons PA, Schreiber SL. DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules. J Am Chem Soc. 2019 Jul 3;141(26):10225-10235. doi: 10.1021/jacs.9b01203. Epub 2019 Jun 25. PubMed PMID: 31184885; PubMed Central PMCID: PMC6681660.

select

Schreiber SL. 1980s Camelot. J Antibiot (Tokyo). 2019 Jun;72(6):323. doi: 10.1038/s41429-019-0174-z. Epub 2019 May 27. PubMed PMID: 31130725.