My Bibliography

select

Outcomes of Pulmonary Arterial Hypertension are Improved in a Specialty Care Center. Chest. . NIHMSID: NIHMS1592497.

select

Fatty Acid and Oxylipin Metabolism Differentiate Isolated Post-Capillary from Combined Pre- and Post-Capillary Pulmonary Hypertension. Circulation. Heart failure. . NIHMSID: NIHMS2192545.

select

Marcinek A, Platz M, Chan S, Floresca K, Rajagopalan K, Golinksi M, Watt D. Unusually long lifetimes of the singlet nitrenes derived from 4-azido-2,3,5,6-tetrafluorobenzamides. The journal of physical chemistry.. 1994; 98(2):412-9.

select

Chan SY, Speck RF, Power C, Gaffen SL, Chesebro B, Goldsmith MA. V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1. J Virol. 1999 Mar;73(3):2350-8. doi: 10.1128/JVI.73.3.2350-2358.1999. PubMed PMID: 9971818; PubMed Central PMCID: PMC104480.

select

Speck RF, Esser U, Penn ML, Eckstein DA, Pulliam L, Chan SY, Goldsmith MA. A trans-receptor mechanism for infection of CD4-negative cells by human immunodeficiency virus type 1. Curr Biol. 1999 May 20;9(10):547-50. doi: 10.1016/s0960-9822(99)80241-3. PubMed PMID: 10339429.

select

Schramm B, Penn ML, Speck RF, Chan SY, De Clercq E, Schols D, Connor RI, Goldsmith MA. Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease. J Virol. 2000 Jan;74(1):184-92. doi: 10.1128/jvi.74.1.184-192.2000. PubMed PMID: 10590105; PubMed Central PMCID: PMC111527.

select

Chan SY, Speck RF, Ma MC, Goldsmith MA. Distinct mechanisms of entry by envelope glycoproteins of Marburg and Ebola (Zaire) viruses. J Virol. 2000 May;74(10):4933-7. doi: 10.1128/jvi.74.10.4933-4937.2000. PubMed PMID: 10775638; PubMed Central PMCID: PMC112022.

select

Chan SY, Ma MC, Goldsmith MA. Differential induction of cellular detachment by envelope glycoproteins of Marburg and Ebola (Zaire) viruses. J Gen Virol. 2000 Sep;81(Pt 9):2155-2159. doi: 10.1099/0022-1317-81-9-2155. PubMed PMID: 10950971.

select

Chan SY, Empig CJ, Welte FJ, Speck RF, Schmaljohn A, Kreisberg JF, Goldsmith MA. Folate receptor-alpha is a cofactor for cellular entry by Marburg and Ebola viruses. Cell. 2001 Jul 13;106(1):117-26. doi: 10.1016/s0092-8674(01)00418-4. PubMed PMID: 11461707.

select

Chan SY, Loscalzo J. Pathogenic mechanisms of pulmonary arterial hypertension. J Mol Cell Cardiol. 2008 Jan;44(1):14-30. doi: 10.1016/j.yjmcc.2007.09.006. Epub 2007 Sep 20. Review. PubMed PMID: 17950310; PubMed Central PMCID: PMC2234575.

select

Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL, Loscalzo J. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 2009 Oct;10(4):273-84. doi: 10.1016/j.cmet.2009.08.015. PubMed PMID: 19808020; PubMed Central PMCID: PMC2759401.

select

Chan SY, Loscalzo J. MicroRNA-210: a unique and pleiotropic hypoxamir. Cell Cycle. 2010 Mar 15;9(6):1072-83. doi: 10.4161/cc.9.6.11006. Epub 2010 Mar 15. Review. PubMed PMID: 20237418; PubMed Central PMCID: PMC2912143.

select

Chan SY, Loscalzo J. Pulmonary vascular disease related to hemodynamic stress in the pulmonary circulation. Compr Physiol. 2011 Jan;1(1):123-39. doi: 10.1002/cphy.c090004. Review. PubMed PMID: 23737167; PubMed Central PMCID: PMC3730284.

select

Baggish AL, Hale A, Weiner RB, Lewis GD, Systrom D, Wang F, Wang TJ, Chan SY. Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training. J Physiol. 2011 Aug 15;589(Pt 16):3983-94. doi: 10.1113/jphysiol.2011.213363. Epub 2011 Jun 20. PubMed PMID: 21690193; PubMed Central PMCID: PMC3179997.

select

Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabási AL, Loscalzo J, Chan SY. MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach. Circulation. 2012 Mar 27;125(12):1520-32. doi: 10.1161/CIRCULATIONAHA.111.060269. Epub 2012 Feb 27. PubMed PMID: 22371328; PubMed Central PMCID: PMC3353408.

select

Chan SY, White K, Loscalzo J. Deciphering the molecular basis of human cardiovascular disease through network biology. Curr Opin Cardiol. 2012 May;27(3):202-9. doi: 10.1097/HCO.0b013e3283515b31. Review. PubMed PMID: 22382498; PubMed Central PMCID: PMC3521498.

select

White K, Loscalzo J, Chan SY. Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension. Pulm Circ. 2012 Jul;2(3):278-90. doi: 10.4103/2045-8932.101395. PubMed PMID: 23130098; PubMed Central PMCID: PMC3487298.

select

Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722. Epub 2012 Jul 11. PubMed PMID: 22787113; PubMed Central PMCID: PMC3534848.

select

Chan SY, Loscalzo J. The emerging paradigm of network medicine in the study of human disease. Circ Res. 2012 Jul 20;111(3):359-74. doi: 10.1161/CIRCRESAHA.111.258541. Review. PubMed PMID: 22821909; PubMed Central PMCID: PMC3425394.

select

Hale AE, White K, Chan SY. Hypoxamirs in Pulmonary Hypertension: Breathing New Life into Pulmonary Vascular Research. Cardiovasc Diagn Ther. 2012 Sep;2(3):200-212. doi: 10.3978/j.issn.2223-3652.2012.08.01. PubMed PMID: 23745175; PubMed Central PMCID: PMC3671932.

select

Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S. Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013 Apr;12(2):280-91. doi: 10.1111/acel.12052. Epub 2013 Feb 28. PubMed PMID: 23399021; PubMed Central PMCID: PMC3602280.

select

Jin RC, Min PK, Chan SY. MicroRNA in the Diseased Pulmonary Vasculature: Implications for the Basic Scientist and Clinician. J Korean Soc Hypertens. 2013 Mar;19(1):1-16. doi: 10.5646/jksh.2013.19.1.1. Epub 2013 Mar 31. PubMed PMID: 26705533; PubMed Central PMCID: PMC4687897.

select

Cottrill KA, Chan SY. Metabolic dysfunction in pulmonary hypertension: the expanding relevance of the Warburg effect. Eur J Clin Invest. 2013 Aug;43(8):855-65. doi: 10.1111/eci.12104. Epub 2013 Apr 26. Review. PubMed PMID: 23617881; PubMed Central PMCID: PMC3736346.

select

Snow JW, Hale AE, Isaacs SK, Baggish AL, Chan SY. Ineffective delivery of diet-derived microRNAs to recipient animal organisms. RNA Biol. 2013 Jul;10(7):1107-16. doi: 10.4161/rna.24909. Epub 2013 May 3. PubMed PMID: 23669076; PubMed Central PMCID: PMC3849158.

select

Nallamshetty S, Chan SY, Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013 Sep;64:20-30. doi: 10.1016/j.freeradbiomed.2013.05.022. Epub 2013 May 24. Review. PubMed PMID: 23712003; PubMed Central PMCID: PMC3762925.

select

Parikh VN, Chan SY. Analysis of microRNA niches: techniques to measure extracellular microRNA and intracellular microRNA in situ. Methods Mol Biol. 2013;1024:157-72. doi: 10.1007/978-1-62703-453-1_12. PubMed PMID: 23719949; PubMed Central PMCID: PMC3753217.

select

Baggish AL, Park J, Min PK, Isaacs S, Parker BA, Thompson PD, Troyanos C, D'Hemecourt P, Dyer S, Thiel M, Hale A, Chan SY. Rapid upregulation and clearance of distinct circulating microRNAs after prolonged aerobic exercise. J Appl Physiol (1985). 2014 Mar 1;116(5):522-31. doi: 10.1152/japplphysiol.01141.2013. Epub 2014 Jan 16. PubMed PMID: 24436293; PubMed Central PMCID: PMC3949215.

select

Cottrill KA, Chan SY, Loscalzo J. Hypoxamirs and mitochondrial metabolism. Antioxid Redox Signal. 2014 Sep 10;21(8):1189-201. doi: 10.1089/ars.2013.5641. Epub 2014 Feb 3. PubMed PMID: 24111795; PubMed Central PMCID: PMC4142855.

select

Maron BA, Oldham WM, Chan SY, Vargas SO, Arons E, Zhang YY, Loscalzo J, Leopold JA. Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis. Circulation. 2014 Jul 8;130(2):168-79. doi: 10.1161/CIRCULATIONAHA.113.007690. Epub 2014 Apr 28. PubMed PMID: 25001622; PubMed Central PMCID: PMC4090713.

select

Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2014 Aug;124(8):3514-28. doi: 10.1172/JCI74773. Epub 2014 Jun 24. PubMed PMID: 24960162; PubMed Central PMCID: PMC4109523.

select

Hale A, Lee C, Annis S, Min PK, Pande R, Creager MA, Julian CG, Moore LG, Mitsialis SA, Hwang SJ, Kourembanas S, Chan SY. An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells. Biochim Biophys Acta. 2014 Nov;1843(11):2528-42. doi: 10.1016/j.bbamcr.2014.06.012. Epub 2014 Jun 28. PubMed PMID: 24983771; PubMed Central PMCID: PMC4158026.

select

Cottrill KA, Chan SY. Investigating pulmonary arterial hypertension from "stem" to stern. Focus on "Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension". Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C413-4. doi: 10.1152/ajpcell.00242.2014. Epub 2014 Jul 16. PubMed PMID: 25031019; PubMed Central PMCID: PMC4154076.

select

Bertero T, Cottrill K, Krauszman A, Lu Y, Annis S, Hale A, Bhat B, Waxman AB, Chau BN, Kuebler WM, Chan SY. The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension. J Biol Chem. 2015 Jan 23;290(4):2069-85. doi: 10.1074/jbc.M114.617845. Epub 2014 Dec 12. PubMed PMID: 25505270; PubMed Central PMCID: PMC4303661.

select

Cottrill K, Chan S. Diet-Derived MicroRNAs: Separating the Dream from Reality. microRNA Diagnostics and Therapeutics. 2014; 1:46-57.

select

Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015;10(2):e0118081. doi: 10.1371/journal.pone.0118081. eCollection 2015. PubMed PMID: 25679506; PubMed Central PMCID: PMC4332500.

select

Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015;10(5):e0126062. doi: 10.1371/journal.pone.0126062. eCollection 2015. PubMed PMID: 25938419; PubMed Central PMCID: PMC4418848.

select

White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. EMBO Mol Med. 2015 Jun;7(6):695-713. doi: 10.15252/emmm.201404511. PubMed PMID: 25825391; PubMed Central PMCID: PMC4459813.

select

Min PK, Chan SY. The biology of circulating microRNAs in cardiovascular disease. Eur J Clin Invest. 2015 Aug;45(8):860-74. doi: 10.1111/eci.12475. Review. PubMed PMID: 26046787; PubMed Central PMCID: PMC4514545.

select

Sherman JH, Munyikwa T, Chan SY, Petrick JS, Witwer KW, Choudhuri S. RNAi technologies in agricultural biotechnology: The Toxicology Forum 40th Annual Summer Meeting. Regul Toxicol Pharmacol. 2015 Nov;73(2):671-80. doi: 10.1016/j.yrtph.2015.09.001. Epub 2015 Sep 9. PubMed PMID: 26361858.

select

Min PK, Park J, Isaacs S, Taylor BA, Thompson PD, Troyanos C, D'Hemecourt P, Dyer S, Chan SY, Baggish AL. Influence of statins on distinct circulating microRNAs during prolonged aerobic exercise. J Appl Physiol (1985). 2016 Mar 15;120(6):711-20. doi: 10.1152/japplphysiol.00654.2015. Epub 2015 Oct 15. PubMed PMID: 26472872; PubMed Central PMCID: PMC5504424.

select

Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep. 2015 Nov 3;13(5):1016-32. doi: 10.1016/j.celrep.2015.09.049. Epub 2015 Oct 22. PubMed PMID: 26565914; PubMed Central PMCID: PMC4644508.

select

Parikh VN, Park J, Nikolic I, Channick R, Yu PB, De Marco T, Hsue PY, Chan SY. Brief Report: Coordinated Modulation of Circulating miR-21 in HIV, HIV-Associated Pulmonary Arterial Hypertension, and HIV/Hepatitis C Virus Coinfection. J Acquir Immune Defic Syndr. 2015 Nov 1;70(3):236-41. doi: 10.1097/QAI.0000000000000741. PubMed PMID: 26473639; PubMed Central PMCID: PMC4610144.

select

Bertero T, Cottrill KA, Annis S, Bhat B, Gochuico BR, Osorio JC, Rosas I, Haley KJ, Corey KE, Chung RT, Nelson Chau B, Chan SY. A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions. Sci Rep. 2015 Dec 15;5:18277. doi: 10.1038/srep18277. PubMed PMID: 26667495; PubMed Central PMCID: PMC4678880.

select

Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J 3rd, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. J Clin Invest. 2016 Sep 1;126(9):3313-35. doi: 10.1172/JCI86387. Epub 2016 Aug 22. PubMed PMID: 27548520; PubMed Central PMCID: PMC5004943.

select

Brittain EL, Chan SY. Integration of complex data sources to provide biologic insight into pulmonary vascular disease (2015 Grover Conference Series). Pulm Circ. 2016 Sep;6(3):251-60. doi: 10.1086/686995. Review. PubMed PMID: 27683602; PubMed Central PMCID: PMC5019078.

select

Chan SY, Snow JW. Uptake and impact of natural diet-derived small RNA in invertebrates: Implications for ecology and agriculture. RNA Biol. 2017 Apr 3;14(4):402-414. doi: 10.1080/15476286.2016.1248329. Epub 2016 Oct 20. Review. PubMed PMID: 27763816; PubMed Central PMCID: PMC5411125.

select

Masood M, Everett CP, Chan SY, Snow JW. Negligible uptake and transfer of diet-derived pollen microRNAs in adult honey bees. RNA Biol. 2016;13(1):109-18. doi: 10.1080/15476286.2015.1128063. PubMed PMID: 26680555; PubMed Central PMCID: PMC4829281.

select

Cavalcante JL, Simon MA, Chan SY. Comprehensive Right-Sided Assessment for Transcatheter Aortic Valve Replacement Risk Stratification: Time for a Change. J Am Soc Echocardiogr. 2017 Jan;30(1):47-51. doi: 10.1016/j.echo.2016.11.006. PubMed PMID: 28063482; PubMed Central PMCID: PMC5813684.

select

Chun HJ, Bonnet S, Chan SY. Translational Advances in the Field of Pulmonary Hypertension. Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than "miR" Words. Am J Respir Crit Care Med. 2017 Jan 15;195(2):167-178. doi: 10.1164/rccm.201604-0886PP. PubMed PMID: 27648944; PubMed Central PMCID: PMC5394787.

select

Negi V, Chan SY. Discerning functional hierarchies of microRNAs in pulmonary hypertension. JCI Insight. 2017 Mar 9;2(5):e91327. doi: 10.1172/jci.insight.91327. Review. PubMed PMID: 28289720; PubMed Central PMCID: PMC5333972.