My Bibliography

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He Q, Schuessler PJ, Srinivasan A, Caprino J, Barbi J, Walker SE. Translation Inhibition by Rocaglamide A Enhances Susceptibility of Yeasts to Caspofungin. bioRxiv. 2025 Sep 22;. doi: 10.1101/2025.09.21.677667. PubMed PMID: 41040306; PubMed Central PMCID: PMC12485697.

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Shankar K, Walker SE. Analysis of divergent gene expression between HPV + and HPV- head and neck squamous cell carcinoma patients. Infect Agent Cancer. 2025 May 21;20(1):31. doi: 10.1186/s13027-025-00663-1. PubMed PMID: 40400005; PubMed Central PMCID: PMC12096591.

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Wegman R, Langberg M, Davis RB, Liu X, Luo M, Yu MC, Walker SE. Protein Arginine Methylation of the Translation Initiation Factor eIF1A Increases Usage of a Near-cognate Start Codon. bioRxiv. 2024 Aug 17;. doi: 10.1101/2024.08.16.608280. PubMed PMID: 39185183; PubMed Central PMCID: PMC11343201.

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Elliff J, Biswas A, Roshan P, Kuppa S, Patterson A, Mattice J, Chinnaraj M, Burd R, Walker SE, Pozzi N, Antony E, Bothner B, Origanti S. Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit. Nucleic Acids Res. 2023 Feb 28;51(4):1803-1822. doi: 10.1093/nar/gkac1266. PubMed PMID: 36651285; PubMed Central PMCID: PMC9976893.

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Smith R, Diba L, Srinivasan A, Zollo R, Ossevoort T, He Q, Colligan S, Dolan M, Vedire Y, Sultana T, Venkatesh M, Arora A, Gawlak S, Washington D, Brackett C, Yao S, Ebos J, Abrams S, Barbi J, Walker SE. Robust eIF4B levels undermine invasive growth and immune evasion mechanisms in murine triple negative breast cancer models. bioRxiv. 2022 September; :2022.09.16.508318. doi: 10.1101/2022.09.16.508318.

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Sahoo A, Zollo RA, Shen S, Ashraf M, Nelson S, Koudelka G, Qu J, Barbi J, Walker SE. Dynamic Phosphorylation Regulates Eukaryotic Translation Initiation Factor 4A Activity During the Cell Cycle. bioRxiv. 2022 August; :2022.08.14.503931. doi: 10.1101/2022.08.14.503931.

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Liu X, Moshiri H, He Q, Sahoo A, Walker SE. Deletion of the N-Terminal Domain of Yeast Eukaryotic Initiation Factor 4B Reprograms Translation and Reduces Growth in Urea. Front Mol Biosci. 2021;8:787781. doi: 10.3389/fmolb.2021.787781. eCollection 2021. PubMed PMID: 35047555; PubMed Central PMCID: PMC8762332.

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Sahoo A, He Q, Walker SE. Flipping the Switch: An Unexpected Role for aEF1B in Modulating aEF1A Interactions with the Ribosome and tRNA. J Mol Biol. 2021 Jul 23;433(15):167052. doi: 10.1016/j.jmb.2021.167052. Epub 2021 May 18. PubMed PMID: 34015279.

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Bowitch A, Sahoo A, Clark AM, Ntangka C, Raut KK, Gollnick P, Yu MC, Pascal SM, Walker SE, Ferkey DM. Methylation of the D2 dopamine receptor affects binding with the human regulatory proteins Par-4 and Calmodulin. MicroPubl Biol. 2021 Feb 9;2021. doi: 10.17912/micropub.biology.000366. PubMed PMID: 33598640; PubMed Central PMCID: PMC7876548.

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Liu X, Schuessler PJ, Sahoo A, Walker SE. Reconstitution and analyses of RNA interactions with eukaryotic translation initiation factors and ribosomal preinitiation complexes. Methods. 2019 Jun 1;162-163:42-53. doi: 10.1016/j.ymeth.2019.03.024. Epub 2019 Mar 26. PubMed PMID: 30926531; PubMed Central PMCID: PMC6612434.

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Sehgal N, Sylves ME, Sahoo A, Chow J, Walker SE, Cullen PJ, Berry JO. CRISPR Gene Editing in Yeast: An Experimental Protocol for an Upper-Division Undergraduate Laboratory Course. Biochem Mol Biol Educ. 2018 Nov;46(6):592-601. doi: 10.1002/bmb.21175. Epub 2018 Oct 12. PubMed PMID: 30311729; PubMed Central PMCID: PMC6615721.

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Munoz AM, Yourik P, Rajagopal V, Nanda JS, Lorsch JR, Walker SE. Active yeast ribosome preparation using monolithic anion exchange chromatography. RNA Biol. 2017 Feb;14(2):188-196. doi: 10.1080/15476286.2016.1270004. Epub 2016 Dec 16. PubMed PMID: 27981882; PubMed Central PMCID: PMC5324736.

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Walker SE, Lorsch J. Sanger dideoxy sequencing of DNA. Methods Enzymol. 2013;529:171-84. doi: 10.1016/B978-0-12-418687-3.00014-8. PubMed PMID: 24011045.

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Walker SE, Lorsch J. RNA purification--precipitation methods. Methods Enzymol. 2013;530:337-43. doi: 10.1016/B978-0-12-420037-1.00019-1. PubMed PMID: 24034331.

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Walker SE, Lorsch J. Reverse transcriptase dideoxy sequencing of RNA. Methods Enzymol. 2013;530:347-59. doi: 10.1016/B978-0-12-420037-1.00020-8. PubMed PMID: 24034332.

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Zhou F, Walker SE, Mitchell SF, Lorsch JR, Hinnebusch AG. Identification and characterization of functionally critical, conserved motifs in the internal repeats and N-terminal domain of yeast translation initiation factor 4B (yeIF4B). J Biol Chem. 2014 Jan 17;289(3):1704-22. doi: 10.1074/jbc.M113.529370. Epub 2013 Nov 27. PubMed PMID: 24285537; PubMed Central PMCID: PMC3894348.

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Walker SE, Zhou F, Mitchell SF, Larson VS, Valasek L, Hinnebusch AG, Lorsch JR. Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains. RNA. 2013 Feb;19(2):191-207. doi: 10.1261/rna.035881.112. Epub 2012 Dec 12. PubMed PMID: 23236192; PubMed Central PMCID: PMC3543093.

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Park EH, Walker SE, Zhou F, Lee JM, Rajagopal V, Lorsch JR, Hinnebusch AG. Yeast eukaryotic initiation factor 4B (eIF4B) enhances complex assembly between eIF4A and eIF4G in vivo. J Biol Chem. 2013 Jan 25;288(4):2340-54. doi: 10.1074/jbc.M112.398537. Epub 2012 Nov 26. PubMed PMID: 23184954; PubMed Central PMCID: PMC3554905.

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Mitchell S, Walker S, Rajagopal V, Aitken C, Lorsch J. Recruiting knotty partners: The roles of translation initiation factors in mRNA recruitment to the eukaryotic ribosome. In: Rodnina M, Wintermeyer W, Green R, editors. Ribosomes [Internet] Vienna: Springer Vienna; 2011. Chapter Chapter 13; 155-169p. Available from: http://link.springer.com/10.1007/978-3-7091-0215-2_13.

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Shin BS, Kim JR, Walker SE, Dong J, Lorsch JR, Dever TE. Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome. Nat Struct Mol Biol. 2011 Oct 16;18(11):1227-34. doi: 10.1038/nsmb.2133. PubMed PMID: 22002225; PubMed Central PMCID: PMC3210414.

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Park EH, Walker SE, Lee JM, Rothenburg S, Lorsch JR, Hinnebusch AG. Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPs in vivo. EMBO J. 2011 Jan 19;30(2):302-16. doi: 10.1038/emboj.2010.312. Epub 2010 Dec 7. PubMed PMID: 21139564; PubMed Central PMCID: PMC3025458.

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Mitchell SF, Walker SE, Algire MA, Park EH, Hinnebusch AG, Lorsch JR. The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway. Mol Cell. 2010 Sep 24;39(6):950-62. doi: 10.1016/j.molcel.2010.08.021. PubMed PMID: 20864040; PubMed Central PMCID: PMC2945613.

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Shoji S, Walker SE, Fredrick K. Ribosomal translocation: one step closer to the molecular mechanism. ACS Chem Biol. 2009 Feb 20;4(2):93-107. doi: 10.1021/cb8002946. Review. PubMed PMID: 19173642; PubMed Central PMCID: PMC3010847.

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Walker SE, Shoji S, Pan D, Cooperman BS, Fredrick K. Role of hybrid tRNA-binding states in ribosomal translocation. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9192-7. doi: 10.1073/pnas.0710146105. Epub 2008 Jun 30. PubMed PMID: 18591673; PubMed Central PMCID: PMC2453706.

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Walker SE, Fredrick K. Preparation and evaluation of acylated tRNAs. Methods. 2008 Feb;44(2):81-6. doi: 10.1016/j.ymeth.2007.09.003. PubMed PMID: 18241790; PubMed Central PMCID: PMC2276730.

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Shoji S, Walker SE, Fredrick K. Reverse translocation of tRNA in the ribosome. Mol Cell. 2006 Dec 28;24(6):931-42. doi: 10.1016/j.molcel.2006.11.025. PubMed PMID: 17189194; PubMed Central PMCID: PMC2661759.

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Walker SE, Fredrick K. Recognition and positioning of mRNA in the ribosome by tRNAs with expanded anticodons. J Mol Biol. 2006 Jul 14;360(3):599-609. doi: 10.1016/j.jmb.2006.05.006. Epub 2006 May 17. PubMed PMID: 16730356; PubMed Central PMCID: PMC2602952.

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McGarry KG, Walker SE, Wang H, Fredrick K. Destabilization of the P site codon-anticodon helix results from movement of tRNA into the P/E hybrid state within the ribosome. Mol Cell. 2005 Nov 23;20(4):613-22. doi: 10.1016/j.molcel.2005.10.007. PubMed PMID: 16307924; PubMed Central PMCID: PMC2631382.