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Reiche ME, Poels K, Bosmans LA, Vos WG, Van Tiel CM, Gijbels MJJ, Aarts SABM, Den Toom M, Beckers L, Weber C, Atzler D, Rensen PCN, Kooijman S, Lutgens E. Adipocytes control hematopoiesis and inflammation through CD40 signaling. Haematologica. 2023 Jul 1;108(7):1873-1885. doi: 10.3324/haematol.2022.281482. PubMed PMID: 36475519; PubMed Central PMCID: PMC10316249.
Ying Z, Tramper N, Zhou E, Boon MR, Rensen PCN, Kooijman S. Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans. Cardiovasc Res. 2023 May 2;119(4):905-918. doi: 10.1093/cvr/cvac131. Review. PubMed PMID: 35944189; PubMed Central PMCID: PMC10153643.
Deprince A, Hennuyer N, Kooijman S, Pronk ACM, Baugé E, Lienard V, Verrijken A, Dirinck E, Vonghia L, Woitrain E, Kloosterhuis NJ, Marez E, Jacquemain P, Wolters JC, Lalloyer F, Eberlé D, Quemener S, Vallez E, Tailleux A, Kouach M, Goossens JF, Raverdy V, Derudas B, Kuivenhoven JA, Croyal M, van de Sluis B, Francque S, Pattou F, Rensen PCN, Staels B, Haas JT. Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism. Hepatology. 2023 Apr 1;77(4):1287-1302. doi: 10.1002/hep.32631. Epub 2022 Jul 15. PubMed PMID: 35735979; PubMed Central PMCID: PMC10026963.
Ying Z, van Eenige R, Beerepoot R, Boon MR, Kloosterhuis NJ, van de Sluis B, Bartelt A, Rensen PCN, Kooijman S. Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway. Pharmacol Res. 2023 Jan;187:106634. doi: 10.1016/j.phrs.2022.106634. Epub 2022 Dec 24. PubMed PMID: 36574856.
Schönke M, Ying Z, Kovynev A, In Het Panhuis W, Binnendijk A, van der Poel S, Pronk ACM, Streefland TCM, Hoekstra M, Kooijman S, Rensen PCN. Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development. FASEB J. 2023 Jan;37(1):e22719. doi: 10.1096/fj.202201304R. PubMed PMID: 36562708.
Vos DY, Wijers M, Smit M, Huijkman N, Kloosterhuis NJ, Wolters JC, Tissink JJ, Pronk ACM, Kooijman S, Rensen PCN, Kuivenhoven JA, van de Sluis B. Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):e29-e45. doi: 10.1161/ATVBAHA.122.318169. Epub 2022 Nov 10. PubMed PMID: 36353989.
Straat ME, Jurado-Fasoli L, Ying Z, Nahon KJ, Janssen LGM, Boon MR, Grabner GF, Kooijman S, Zimmermann R, Giera M, Rensen PCN, Martinez-Tellez B. Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial. EBioMedicine. 2022 Dec;86:104349. doi: 10.1016/j.ebiom.2022.104349. Epub 2022 Nov 11. PubMed PMID: 36371986; PubMed Central PMCID: PMC9663865.
Sardjoe Mishre ASD, Straat ME, Martinez-Tellez B, Mendez Gutierrez A, Kooijman S, Boon MR, Dzyubachyk O, Webb A, Rensen PCN, Kan HE. The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue. J Med Syst. 2022 Nov 2;46(12):89. doi: 10.1007/s10916-022-01871-7. PubMed PMID: 36319877; PubMed Central PMCID: PMC9626432.
Svedlund Eriksson E, Johansson I, Mårtensson AKF, Lantero Rodriguez M, Schilperoort M, Kroon J, Kooijman S, Omerovic E, Andersson L, Levin MC, Rensen PCN, Tivesten Å. Castration of Male Mice Induces Metabolic Remodeling of the Heart. J Endocr Soc. 2022 Oct 11;6(11):bvac132. doi: 10.1210/jendso/bvac132. eCollection 2022 Oct 11. PubMed PMID: 36249410; PubMed Central PMCID: PMC9557843.
In Het Panhuis W, Schönke M, Siebeler R, Afkir S, Baelde R, Pronk ACM, Streefland TCM, Sips HCM, Lalai RA, Rensen PCN, Kooijman S. Aging attenuates diurnal lipid uptake by brown adipose tissue. Aging (Albany NY). 2022 Oct 4;14(19):7734-7751. doi: 10.18632/aging.204318. Epub 2022 Oct 4. PubMed PMID: 36202134; PubMed Central PMCID: PMC9596214.
Dijk W, Di Filippo M, Kooijman S, van Eenige R, Rimbert A, Caillaud A, Thedrez A, Arnaud L, Pronk A, Garçon D, Sotin T, Lindenbaum P, Ozcariz Garcia E, Pais de Barros JP, Duvillard L, Si-Tayeb K, Amigo N, Le Questel JY, Rensen PCN, Le May C, Moulin P, Cariou B. Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia. Circulation. 2022 Sep 6;146(10):724-739. doi: 10.1161/CIRCULATIONAHA.121.057978. Epub 2022 Jul 28. PubMed PMID: 35899625; PubMed Central PMCID: PMC9439636.
Koorneef LL, van der Meulen M, Kooijman S, Sánchez-López E, Scheerstra JF, Voorhoeve MC, Ramesh ANN, Rensen PCN, Giera M, Kroon J, Meijer OC. Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone. Front Endocrinol (Lausanne). 2022;13:960279. doi: 10.3389/fendo.2022.960279. eCollection 2022. PubMed PMID: 36034417; PubMed Central PMCID: PMC9399852.
Straat ME, Martinez-Tellez B, Nahon KJ, Janssen LGM, Verhoeven A, van der Zee L, Mulder MT, Kooijman S, Boon MR, van Lennep JER, Cobbaert CM, Giera M, Rensen PCN. Comprehensive (apo)lipoprotein profiling in patients with genetic hypertriglyceridemia using LC-MS and NMR spectroscopy. J Clin Lipidol. 2022 Jul-Aug;16(4):472-482. doi: 10.1016/j.jacl.2022.04.004. Epub 2022 Apr 30. PubMed PMID: 35568684.
van Eenige R, In Het Panhuis W, Schönke M, Jouffe C, Devilee TH, Siebeler R, Streefland TCM, Sips HCM, Pronk ACM, Vorderman RHP, Mei H, van Klinken JB, van Weeghel M, Uhlenhaut NH, Kersten S, Rensen PCN, Kooijman S. Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue. Mol Metab. 2022 Jun;60:101497. doi: 10.1016/j.molmet.2022.101497. Epub 2022 Apr 10. PubMed PMID: 35413480; PubMed Central PMCID: PMC9048098.
Straat ME, Martinez-Tellez B, Sardjoe Mishre A, Verkleij MMA, Kemmeren M, Pelsma ICM, Alcantara JMA, Mendez-Gutierrez A, Kooijman S, Boon MR, Rensen PCN. Cold-Induced Thermogenesis Shows a Diurnal Variation That Unfolds Differently in Males and Females. J Clin Endocrinol Metab. 2022 May 17;107(6):1626-1635. doi: 10.1210/clinem/dgac094. PubMed PMID: 35176767; PubMed Central PMCID: PMC9113803.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D. Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue. Cell Metab. 2022 Apr 5;34(4):533-548.e12. doi: 10.1016/j.cmet.2022.02.016. Epub 2022 Mar 18. PubMed PMID: 35305295; PubMed Central PMCID: PMC9039922.
In Het Panhuis W, Tsaalbi-Shtylik A, Schönke M, van Harmelen V, Pronk ACM, Streefland TCM, Sips HCM, Afkir S, Willems van Dijk K, Rensen PCN, de Wind N, Kooijman S. Rev1 deficiency induces replication stress to cause metabolic dysfunction differently in males and females. Am J Physiol Endocrinol Metab. 2022 Mar 1;322(3):E319-E329. doi: 10.1152/ajpendo.00357.2021. Epub 2022 Feb 14. PubMed PMID: 35156394.
Liu C, Schönke M, Zhou E, Li Z, Kooijman S, Boon MR, Larsson M, Wallenius K, Dekker N, Barlind L, Peng XR, Wang Y, Rensen PCN. Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis. Cardiovasc Res. 2022 Jan 29;118(2):489-502. doi: 10.1093/cvr/cvab076. PubMed PMID: 33693480; PubMed Central PMCID: PMC8803070.
Wang XL, Kooijman S, Gao Y, Tzeplaeff L, Cosquer B, Milanova I, Wolff SEC, Korpel N, Champy MF, Petit-Demoulière B, Goncalves Da Cruz I, Sorg-Guss T, Rensen PCN, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX. Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity. Mol Psychiatry. 2021 Nov;26(11):6336-6349. doi: 10.1038/s41380-021-01169-z. Epub 2021 May 28. PubMed PMID: 34050326; PubMed Central PMCID: PMC8760060.
Winter EM, Kooijman S, Appelman-Dijkstra NM, Meijer OC, Rensen PC, Schilperoort M. Chronobiology and Chronotherapy of Osteoporosis. JBMR Plus. 2021 Oct;5(10):e10504. doi: 10.1002/jbm4.10504. eCollection 2021 Oct. Review. PubMed PMID: 34693186; PubMed Central PMCID: PMC8520066.
Schilperoort M, Kroon J, Kooijman S, Smit AE, Gentenaar M, Mletzko K, Schmidt FN, van Ruijven L, Busse B, Pereira AM, Appelman-Dijkstra NM, Bravenboer N, Rensen PCN, Meijer OC, Winter EM. Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice. Aging Cell. 2021 Oct;20(10):e13474. doi: 10.1111/acel.13474. Epub 2021 Sep 30. PubMed PMID: 34592793; PubMed Central PMCID: PMC8520718.
Lantero Rodriguez M, Schilperoort M, Johansson I, Svedlund Eriksson E, Palsdottir V, Kroon J, Henricsson M, Kooijman S, Ericson M, Borén J, Ohlsson C, Jansson JO, Levin MC, Rensen PCN, Tivesten Å. Testosterone reduces metabolic brown fat activity in male mice. J Endocrinol. 2021 Sep 3;251(1):83-96. doi: 10.1530/JOE-20-0263. PubMed PMID: 34370693.
Florijn BW, Duijs JMGJ, Klaver M, Kuipers EN, Kooijman S, Prins J, Zhang H, Sips HCM, Stam W, Hanegraaf M, Limpens RWAL, Nieuwland R, van Rijn BB, Rabelink TJ, Rensen PCN, den Heijer M, Bijkerk R, van Zonneveld AJ. Estradiol-driven metabolism in transwomen associates with reduced circulating extracellular vesicle microRNA-224/452. Eur J Endocrinol. 2021 Aug 27;185(4):539-552. doi: 10.1530/EJE-21-0267. PubMed PMID: 34342596; PubMed Central PMCID: PMC8436186.
Clemente-Olivo MP, Habibe JJ, Vos M, Ottenhoff R, Jongejan A, Herrema H, Zelcer N, Kooijman S, Rensen PCN, van Raalte DH, Nieuwdorp M, Eringa EC, de Vries CJ. Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity. Metabolism. 2021 Aug;121:154815. doi: 10.1016/j.metabol.2021.154815. Epub 2021 Jun 11. PubMed PMID: 34119536.
Straat ME, Hogenboom R, Boon MR, Rensen PCN, Kooijman S. Circadian control of brown adipose tissue. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158961. doi: 10.1016/j.bbalip.2021.158961. Epub 2021 Apr 30. Review. PubMed PMID: 33933649.
Hoogerland JA, Peeks F, Hijmans BS, Wolters JC, Kooijman S, Bos T, Bleeker A, van Dijk TH, Wolters H, Gerding A, van Eunen K, Havinga R, Pronk ACM, Rensen PCN, Mithieux G, Rajas F, Kuipers F, Reijngoud DJ, Derks TGJ, Oosterveer MH. Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia. J Inherit Metab Dis. 2021 Jul;44(4):879-892. doi: 10.1002/jimd.12380. Epub 2021 Apr 7. PubMed PMID: 33739445; PubMed Central PMCID: PMC8360207.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. PubMed PMID: 34048700; PubMed Central PMCID: PMC8238500.
Kroon J, Viho EMG, Gentenaar M, Koorneef LL, van Kooten C, Rensen PCN, Kooijman S, Hunt H, Meijer OC. The development of novel glucocorticoid receptor antagonists: From rational chemical design to therapeutic efficacy in metabolic disease models. Pharmacol Res. 2021 Jun;168:105588. doi: 10.1016/j.phrs.2021.105588. Epub 2021 Mar 31. PubMed PMID: 33798733.
Zhou E, Li Z, Nakashima H, Choukoud A, Kooijman S, Berbée JFP, Rensen PCN, Wang Y. Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice. Pharmacol Res. 2021 May;167:105524. doi: 10.1016/j.phrs.2021.105524. Epub 2021 Mar 2. PubMed PMID: 33667684.
Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S. A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function. Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 3. PubMed PMID: 33548499; PubMed Central PMCID: PMC7907824.
Ying Z, Boon MR, Coskun T, Kooijman S, Rensen PCN. A simplified procedure to trace triglyceride-rich lipoprotein metabolism in vivo. Physiol Rep. 2021 Apr;9(8):e14820. doi: 10.14814/phy2.14820. PubMed PMID: 33945228; PubMed Central PMCID: PMC8095365.
van Eenige R, Ying Z, Tambyrajah L, Pronk ACM, Blomberg N, Giera M, Wang Y, Coskun T, van der Stelt M, Rensen PCN, Kooijman S. Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice. J Lipid Res. 2021;62:100070. doi: 10.1016/j.jlr.2021.100070. Epub 2021 Mar 23. PubMed PMID: 33766515; PubMed Central PMCID: PMC8082266.
Held NM, Buijink MR, Elfrink HL, Kooijman S, Janssens GE, Luyf ACM, Pras-Raves ML, Vaz FM, Michel S, Houtkooper RH, van Weeghel M. Aging selectively dampens oscillation of lipid abundance in white and brown adipose tissue. Sci Rep. 2021 Mar 15;11(1):5932. doi: 10.1038/s41598-021-85455-4. PubMed PMID: 33723320; PubMed Central PMCID: PMC7961067.
Blauw LL, Noordam R, van der Laan SW, Trompet S, Kooijman S, van Heemst D, Jukema JW, van Setten J, de Borst GJ, Tybjærg-Hansen A, Pasterkamp G, Berbée JFP, Rensen PCN. Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes. J Clin Med. 2021 Mar 1;10(5). doi: 10.3390/jcm10050932. PubMed PMID: 33804309; PubMed Central PMCID: PMC7957774.
Wang XL, Wolff SEC, Korpel N, Milanova I, Sandu C, Rensen PCN, Kooijman S, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX. Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism. Front Immunol. 2020;11:586399. doi: 10.3389/fimmu.2020.586399. eCollection 2020. PubMed PMID: 33363534; PubMed Central PMCID: PMC7753637.
Schilperoort M, Rensen PCN, Kooijman S. Time for Novel Strategies to Mitigate Cardiometabolic Risk in Shift Workers. Trends Endocrinol Metab. 2020 Dec;31(12):952-964. doi: 10.1016/j.tem.2020.10.005. Epub 2020 Nov 9. Review. PubMed PMID: 33183967.
Schilperoort M, van den Berg R, Coomans CP, Khedoe PPSJ, Ramkisoensing A, Boekestijn S, Wang Y, Berbée JFP, Meijer JH, Biermasz NR, Rensen PCN, Kooijman S. Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice. J Biol Rhythms. 2020 Dec;35(6):598-611. doi: 10.1177/0748730420951320. Epub 2020 Sep 11. PubMed PMID: 32915671; PubMed Central PMCID: PMC7683885.
Genzel L, Adan R, Berns A, van den Beucken JJJP, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, van Dam AM, Deen PMT, van Dijk KW, Eggen BJL, Elgersma Y, Erdogan I, Englitz B, Fentener van Vlissingen JM, la Fleur S, Fouchier R, Fitzsimons CP, Frieling W, Haagmans B, Heesters BA, Henckens MJAG, Herfst S, Hol E, van den Hove D, de Jonge MI, Jonkers J, Joosten LAB, Kalsbeek A, Kamermans M, Kampinga HH, Kas MJ, Keijer J, Kersten S, Kiliaan AJ, Kooij TWA, Kooijman S, Koopman WJH, Korosi A, Krugers HJ, Kuiken T, Kushner SA, Langermans JAM, Lesscher HMB, Lucassen PJ, Lutgens E, Netea MG, Noldus LPJJ, van der Meer JWM, Meye FJ, Mul JD, van Oers K, Olivier JDA, Pasterkamp RJ, Philippens IHCHM, Prickaerts J, Pollux BJA, Rensen PCN, van Rheenen J, van Rij RP, Ritsma L, Rockx BHG, Roozendaal B, van Schothorst EM, Stittelaar K, Stockhofe N, Swaab DF, de Swart RL, Vanderschuren LJMJ, de Vries TJ, de Vrij F, van Wezel R, Wierenga CJ, Wiesmann M, Willuhn I, de Zeeuw CI, Homberg JR. How the COVID-19 pandemic highlights the necessity of animal research. Curr Biol. 2020 Nov 2;30(21):4328. doi: 10.1016/j.cub.2020.10.033. PubMed PMID: 33142090; PubMed Central PMCID: PMC7605800.
Nahon KJ, Janssen LGM, Sardjoe Mishre ASD, Bilsen MP, van der Eijk JA, Botani K, Overduin LA, Ruiz JR, Burakiewicz J, Dzyubachyk O, Webb AG, Kan HE, Berbée JFP, van Klinken JB, van Dijk KW, van Weeghel M, Vaz FM, Coskun T, Jazet IM, Kooijman S, Martinez-Tellez B, Boon MR, Rensen PCN. The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men. Diabetes Obes Metab. 2020 Nov;22(11):2032-2044. doi: 10.1111/dom.14120. Epub 2020 Jul 29. PubMed PMID: 32558052; PubMed Central PMCID: PMC7771034.
Li Z, de Jonge WJ, Wang Y, Rensen PCN, Kooijman S. Electrical Neurostimulation Promotes Brown Adipose Tissue Thermogenesis. Front Endocrinol (Lausanne). 2020;11:567545. doi: 10.3389/fendo.2020.567545. eCollection 2020. PubMed PMID: 33101199; PubMed Central PMCID: PMC7555256.
Genzel L, Adan R, Berns A, van den Beucken JJJP, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, van Dam AM, Deen PMT, van Dijk KW, Eggen BJL, Elgersma Y, Erdogan I, Englitz B, Fentener van Vlissingen JM, la Fleur S, Fouchier R, Fitzsimons CP, Frieling W, Haagmans B, Heesters BA, Henckens MJAG, Herfst S, Hol E, van den Hove D, de Jonge MI, Jonkers J, Joosten LAB, Kalsbeek A, Kamermans M, Kampinga HH, Kas MJ, Keijer JA, Kersten S, Kiliaan AJ, Kooij TWA, Kooijman S, Koopman WJH, Korosi A, Krugers HJ, Kuiken T, Kushner SA, Langermans JAM, Lesscher HMB, Lucassen PJ, Lutgens E, Netea MG, Noldus LPJJ, van der Meer JWM, Meye FJ, Mul JD, van Oers K, Olivier JDA, Pasterkamp RJ, Philippens IHCHM, Prickaerts J, Pollux BJA, Rensen PCN, van Rheenen J, van Rij RP, Ritsma L, Rockx BHG, Roozendaal B, van Schothorst EM, Stittelaar K, Stockhofe N, Swaab DF, de Swart RL, Vanderschuren LJMJ, de Vries TJ, de Vrij F, van Wezel R, Wierenga CJ, Wiesmann M, Willuhn I, de Zeeuw CI, Homberg JR. How the COVID-19 pandemic highlights the necessity of animal research. Curr Biol. 2020 Sep 21;30(18):R1014-R1018. doi: 10.1016/j.cub.2020.08.030. Epub 2020 Aug 10. PubMed PMID: 32961149; PubMed Central PMCID: PMC7416712.
van Eenige R, Verhave PS, Koemans PJ, Tiebosch IACW, Rensen PCN, Kooijman S. RandoMice, a novel, user-friendly randomization tool in animal research. PLoS One. 2020;15(8):e0237096. doi: 10.1371/journal.pone.0237096. eCollection 2020. PubMed PMID: 32756603; PubMed Central PMCID: PMC7406044.
Blondin DP, Nielsen S, Kuipers EN, Severinsen MC, Jensen VH, Miard S, Jespersen NZ, Kooijman S, Boon MR, Fortin M, Phoenix S, Frisch F, Guérin B, Turcotte ÉE, Haman F, Richard D, Picard F, Rensen PCN, Scheele C, Carpentier AC. Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation. Cell Metab. 2020 Aug 4;32(2):287-300.e7. doi: 10.1016/j.cmet.2020.07.005. PubMed PMID: 32755608.
In Het Panhuis W, Kooijman S, Brouwers B, Verhoeven A, Pronk ACM, Streefland TCM, Giera M, Schrauwen P, Rensen PCN, Schönke M. Mild Exercise Does Not Prevent Atherosclerosis in APOE*3-Leiden.CETP Mice or Improve Lipoprotein Profile of Men with Obesity. Obesity (Silver Spring). 2020 Jul;28 Suppl 1(Suppl 1):S93-S103. doi: 10.1002/oby.22799. Epub 2020 Jun 17. PubMed PMID: 32645256; PubMed Central PMCID: PMC7496605.
van Alem CMA, Schmidbauer M, Rong S, Derlin K, Schmitz J, Bräsen JH, Thorenz A, Chen R, Ruben JM, Winter EM, Schilperoort M, Kooijman S, Lalai RA, Metselaar JM, Klemann C, Meier M, van Kooten C, Gueler F, Rotmans JI. Liposomal Delivery Improves the Efficacy of Prednisolone to Attenuate Renal Inflammation in a Mouse Model of Acute Renal Allograft Rejection. Transplantation. 2020 Apr;104(4):744-753. doi: 10.1097/TP.0000000000003060. PubMed PMID: 31929419; PubMed Central PMCID: PMC7147400.
Janssen LGM, Van Dam AD, Hanssen MJW, Kooijman S, Nahon KJ, Reinders H, Jazet IM, Van Marken Lichtenbelt WD, Rensen PCN, Appelman-Dijkstra NM, Boon MR. Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men. Diabetes Metab J. 2020 Apr;44(2):326-335. doi: 10.4093/dmj.2019.0031. Epub 2019 Oct 31. PubMed PMID: 31701693; PubMed Central PMCID: PMC7188965.
Hoekstra M, van der Sluis RJ, Hildebrand RB, Lammers B, Zhao Y, Praticò D, van Berkel TJC, Rensen PCN, Kooijman S, Jauhiainen M, van Eck M. Disruption of Phospholipid Transfer Protein-Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):611-623. doi: 10.1161/ATVBAHA.119.313862. Epub 2020 Jan 16. PubMed PMID: 31941380.
Schilperoort M, Bravenboer N, Lim J, Mletzko K, Busse B, van Ruijven L, Kroon J, Rensen PCN, Kooijman S, Winter EM. Circadian disruption by shifting the light-dark cycle negatively affects bone health in mice. FASEB J. 2020 Jan;34(1):1052-1064. doi: 10.1096/fj.201901929R. Epub 2019 Nov 28. PubMed PMID: 31914701.
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