My Bibliography

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Cutting T, Hartman RE. Underlying mechanisms of (R,S)-ketamine’s treatment efficacy for post-traumatic stress disorder and depression: a review. Medicine Advances. Forthcoming.

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Creel WT, Randhawa S, Hartman RE. Stem Cell Therapy for Traumatic Brain Injury: Translational Mechanisms, Biomarkers, and Clinical Trials. Stem Cell Rev Rep. 2026 Aug;22(6):2808-2823. doi: 10.1007/s12015-026-11175-9. Epub 2026 Jun 18. Review. PubMed PMID: 42313238; PubMed Central PMCID: PMC13354699.

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Creel WT, Brenner CA, Hartman RE. Regional and cannabis-related differences in prefrontal multiscale entropy of resting-state EEG. Clin Neurophysiol Pract. 2026;11:135-141. doi: 10.1016/j.cnp.2026.02.003. eCollection 2026. PubMed PMID: 41768209; PubMed Central PMCID: PMC12937142.

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Creel WT, Seibly GD, Brenner CA, Hartman RE. Altered entropy modulation in bipolar disorder: EEG entropy measures during steady-state auditory entrainment. J Affect Disord. 2026 May 15;401:121261. doi: 10.1016/j.jad.2026.121261. Epub 2026 Feb 2. PubMed PMID: 41638500.

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Morgan M, Lopez Rodriguez Z, Hartman RE. Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease. Animal Model Exp Med. 2026 Feb;9(2):217-236. doi: 10.1002/ame2.70106. Epub 2026 Jan 4. PubMed PMID: 41486615; PubMed Central PMCID: PMC13042358.

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Creel WT, Hartman RE. EEG entropy modulation as a biomarker of emotion regulation and resilience. IBRO Neurosci Rep. 2025 Dec;19:947-954. doi: 10.1016/j.ibneur.2025.10.013. eCollection 2025 Dec. Review. PubMed PMID: 41280140; PubMed Central PMCID: PMC12639470.

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Tabaza R, Hartman RE. Impact of Gut-Brain Axis and Probiotics on Alzheimer's Disease. Neurol Int. 2025 Sep 24;17(10). doi: 10.3390/neurolint17100153. Review. PubMed PMID: 41149774; PubMed Central PMCID: PMC12566682.

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Bishara MA, Chum PP, Miot FEL, Hooda A, Hartman RE, Behringer EJ. Molecular pathogenesis of Alzheimer's disease onset in a mouse model: effects of cannabidiol treatment. Front Neurosci. 2025;19:1667585. doi: 10.3389/fnins.2025.1667585. eCollection 2025. PubMed PMID: 40979532; PubMed Central PMCID: PMC12446314.

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Salek A, Hartman RE. The placebo and nocebo phenomena – A modern outlook. International Journal of Neurobiology. 2022 May; 4(2):1. doi: 10.36266/IJN/147.

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Kozlova EV, Valdez MC, Denys ME, Bishay AE, Krum JM, Rabbani KM, Carrillo V, Gonzalez GM, Lampel G, Tran JD, Vazquez BM, Anchondo LM, Uddin SA, Huffman NM, Monarrez E, Olomi DS, Chinthirla BD, Hartman RE, Kodavanti PRS, Chompre G, Phillips AL, Stapleton HM, Henkelmann B, Schramm KW, Curras-Collazo MC. Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. Arch Toxicol. 2022 Jan;96(1):335-365. doi: 10.1007/s00204-021-03163-4. Epub 2021 Oct 23. PubMed PMID: 34687351; PubMed Central PMCID: PMC8536480.

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Bellinger DL, Dulcich MS, Molinaro C, Gifford P, Lorton D, Gridley DS, Hartman RE. Psychosocial Stress and Age Influence Depression and Anxiety-Related Behavior, Drive Tumor Inflammatory Cytokines and Accelerate Prostate Cancer Growth in Mice. Front Oncol. 2021;11:703848. doi: 10.3389/fonc.2021.703848. eCollection 2021. PubMed PMID: 34604038; PubMed Central PMCID: PMC8481826.

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Hartman RE, Patel D. Dietary Approaches to the Management of Autism Spectrum Disorders. Adv Neurobiol. 2020;24:547-571. doi: 10.1007/978-3-030-30402-7_19. Review. PubMed PMID: 32006373.

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Lakshmi S, Essa MM, Hartman RE, Guillemin GJ, Sivan S, Elumalai P. Exosomes in Alzheimer's Disease: Potential Role as Pathological Mediators, Biomarkers and Therapeutic Targets. Neurochem Res. 2020 Nov;45(11):2553-2559. doi: 10.1007/s11064-020-03111-1. Epub 2020 Aug 25. Review. PubMed PMID: 32840760.

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Hartman RE, Nathan NH, Ghosh N, Pernia CD, Law J, Nuryyev R, Plaia A, Yusof A, Tone B, Dulcich M, Wakeman DR, Dilmac N, Niles WD, Sidman RL, Obenaus A, Snyder EY, Ashwal S. A Biomarker for Predicting Responsiveness to Stem Cell Therapy Based on Mechanism-of-Action: Evidence from Cerebral Injury. Cell Rep. 2020 May 12;31(6):107622. doi: 10.1016/j.celrep.2020.107622. PubMed PMID: 32402283.

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Tan A, Morton KR, Lee JW, Hartman R, Lee G. Adverse childhood experiences and depressive symptoms: Protective effects of dietary flavonoids. J Psychosom Res. 2020 Apr;131:109957. doi: 10.1016/j.jpsychores.2020.109957. Epub 2020 Feb 11. PubMed PMID: 32088426.

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Knox-Concepcion KR, Figueroa JD, Hartman RE, Li Y, Zhang L. Repression of the Glucocorticoid Receptor Increases Hypoxic-Ischemic Brain Injury in the Male Neonatal Rat. Int J Mol Sci. 2019 Jul 16;20(14). doi: 10.3390/ijms20143493. PubMed PMID: 31315247; PubMed Central PMCID: PMC6678481.

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Jullienne A, Hamer M, Haddad E, Morita A, Gifford P, Hartman R, Pearce WJ, Tang J, Zhang JH, Obenaus A. Acute intranasal osteopontin treatment in male rats following TBI increases the number of activated microglia but does not alter lesion characteristics. J Neurosci Res. 2020 Jan;98(1):141-154. doi: 10.1002/jnr.24405. Epub 2019 Mar 20. PubMed PMID: 30892744; PubMed Central PMCID: PMC6754315.

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Bajwa NM, Lee JB, Halavi S, Hartman RE, Obenaus A. Repeated isoflurane in adult male mice leads to acute and persistent motor decrements with long-term modifications in corpus callosum microstructural integrity. J Neurosci Res. 2019 Mar;97(3):332-345. doi: 10.1002/jnr.24343. Epub 2018 Nov 5. PubMed PMID: 30394562.

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Maloney SE, Creeley CE, Hartman RE, Yuede CM, Zorumski CF, Jevtovic-Todorovic V, Dikranian K, Noguchi KK, Farber NB, Wozniak DF. Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopment. Neurobiol Learn Mem. 2019 Nov;165:106834. doi: 10.1016/j.nlm.2018.03.014. Epub 2018 Mar 14. Review. PubMed PMID: 29550366; PubMed Central PMCID: PMC6179938.

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Wan W, Ding Y, Xie Z, Li Q, Yan F, Budbazar E, Pearce WJ, Hartman R, Obenaus A, Zhang JH, Jiang Y, Tang J. PDGFR-β modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-κB pathway in subarachnoid hemorrhage rats. J Cereb Blood Flow Metab. 2019 Jul;39(7):1369-1380. doi: 10.1177/0271678X18760954. Epub 2018 Feb 26. PubMed PMID: 29480757; PubMed Central PMCID: PMC6668513.

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Bellone JA, Murray JR, Jorge P, Fogel TG, Kim M, Wallace DR, Hartman RE. Pomegranate supplementation improves cognitive and functional recovery following ischemic stroke: A randomized trial. Nutr Neurosci. 2019 Oct;22(10):738-743. doi: 10.1080/1028415X.2018.1436413. Epub 2018 Feb 13. PubMed PMID: 29433376.

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Hartman RE, Ross DM. Effects and mechanisms of actions of phytochemicals on Alzheimer's disease neuropathology. Front Biosci (Elite Ed). 2018 Jan 1;10(2):300-333. doi: 10.2741/e824. Review. PubMed PMID: 28930620.

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Rudobeck E, Bellone JA, Szücs A, Bonnick K, Mehrotra-Carter S, Badaut J, Nelson GA, Hartman RE, Vlkolinský R. Low-dose proton radiation effects in a transgenic mouse model of Alzheimer's disease - Implications for space travel. PLoS One. 2017;12(11):e0186168. doi: 10.1371/journal.pone.0186168. eCollection 2017. PubMed PMID: 29186131; PubMed Central PMCID: PMC5706673.

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Zhang JH, Obenaus A, Liebeskind DS, Tang J, Hartman R, Pearce WJ. Recanalization, reperfusion, and recirculation in stroke. J Cereb Blood Flow Metab. 2017 Dec;37(12):3818-3823. doi: 10.1177/0271678X17732695. Epub 2017 Sep 19. PubMed PMID: 28925323; PubMed Central PMCID: PMC5718333.

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Hartman RE, Thorndyke EC 3rd. Patterns of Behavioral Deficits in Rodents Following Brain Injury Across Species, Gender, and Experimental Model. Acta Neurochir Suppl. 2016;121:71-5. doi: 10.1007/978-3-319-18497-5_12. PubMed PMID: 26463925.

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Manaenko A, Yang P, Nowrangi D, Budbazar E, Hartman RE, Obenaus A, Pearce WJ, Zhang JH, Tang J. Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice. J Cereb Blood Flow Metab. 2018 Jan;38(1):87-102. doi: 10.1177/0271678X16679169. Epub 2016 Nov 19. PubMed PMID: 27864464; PubMed Central PMCID: PMC5757435.

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Li Y, Ma Q, Dasgupta C, Halavi S, Hartman RE, Xiao D, Zhang L. Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood. Mol Neurobiol. 2017 Aug;54(6):3988-3999. doi: 10.1007/s12035-016-9957-4. Epub 2016 Jun 16. PubMed PMID: 27311770; PubMed Central PMCID: PMC5161729.

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Yang P, Manaenko A, Xu F, Miao L, Wang G, Hu X, Guo ZN, Hu Q, Hartman RE, Pearce WJ, Obenaus A, Zhang JH, Chen G, Tang J. Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model. Exp Neurol. 2016 Sep;283(Pt A):157-64. doi: 10.1016/j.expneurol.2016.06.010. Epub 2016 Jun 11. PubMed PMID: 27302678; PubMed Central PMCID: PMC5175487.

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Bellone JA, Gifford PS, Nishiyama NC, Hartman RE, Mao XW. Long-term effects of simulated microgravity and/or chronic exposure to low-dose gamma radiation on behavior and blood-brain barrier integrity. NPJ Microgravity. 2016;2:16019. doi: 10.1038/npjmgrav.2016.19. eCollection 2016. PubMed PMID: 28725731; PubMed Central PMCID: PMC5516431.

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Yang P, Wu J, Miao L, Manaenko A, Matei N, Zhang Y, Xu L, Pearce WJ, Hartman RE, Obenaus A, Zhang JH, Xu F, Tang J. Platelet-Derived Growth Factor Receptor-β Regulates Vascular Smooth Muscle Cell Phenotypic Transformation and Neuroinflammation After Intracerebral Hemorrhage in Mice. Crit Care Med. 2016 Jun;44(6):e390-402. doi: 10.1097/CCM.0000000000001425. PubMed PMID: 26646459; PubMed Central PMCID: PMC4868636.

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Wu J, Zhang Y, Yang P, Enkhjargal B, Manaenko A, Tang J, Pearce WJ, Hartman R, Obenaus A, Chen G, Zhang JH. Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats. Stroke. 2016 May;47(5):1319-27. doi: 10.1161/STROKEAHA.115.011552. Epub 2016 Mar 22. PubMed PMID: 27006454; PubMed Central PMCID: PMC4846549.

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Ma Q, Dasgupta C, Li Y, Bajwa NM, Xiong F, Harding B, Hartman R, Zhang L. Inhibition of microRNA-210 provides neuroprotection in hypoxic-ischemic brain injury in neonatal rats. Neurobiol Dis. 2016 May;89:202-12. doi: 10.1016/j.nbd.2016.02.011. Epub 2016 Feb 11. PubMed PMID: 26875527; PubMed Central PMCID: PMC4785034.

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Bajwa NM, Halavi S, Hamer M, Semple BD, Noble-Haeusslein LJ, Baghchechi M, Hiroto A, Hartman RE, Obenaus A. Mild Concussion, but Not Moderate Traumatic Brain Injury, Is Associated with Long-Term Depression-Like Phenotype in Mice. PLoS One. 2016;11(1):e0146886. doi: 10.1371/journal.pone.0146886. eCollection 2016. PubMed PMID: 26796696; PubMed Central PMCID: PMC4721654.

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Baerresen KM, Miller KJ, Hanson ER, Miller JS, Dye RV, Hartman RE, Vermeersch D, Small GW. Neuropsychological tests for predicting cognitive decline in older adults. Neurodegener Dis Manag. 2015;5(3):191-201. doi: 10.2217/nmt.15.7. PubMed PMID: 26107318; PubMed Central PMCID: PMC4511118.

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Li Y, Ma Q, Halavi S, Concepcion K, Hartman RE, Obenaus A, Xiao D, Zhang L. Fetal stress-mediated hypomethylation increases the brain susceptibility to hypoxic-ischemic injury in neonatal rats. Exp Neurol. 2016 Jan;275 Pt 1(0 1):1-10. doi: 10.1016/j.expneurol.2015.10.007. Epub 2015 Oct 24. PubMed PMID: 26597542; PubMed Central PMCID: PMC4688116.

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Bellone JA, Rudobeck E, Hartman RE, Szücs A, Vlkolinský R. A Single Low Dose of Proton Radiation Induces Long-Term Behavioral and Electrophysiological Changes in Mice. Radiat Res. 2015 Aug;184(2):193-202. doi: 10.1667/rr13903.1. Epub 2015 Jul 24. PubMed PMID: 26207690.

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Karain B, Xu D, Bellone JA, Hartman RE, Shi WX. Rat globus pallidus neurons: functional classification and effects of dopamine depletion. Synapse. 2015 Jan;69(1):41-51. doi: 10.1002/syn.21783. Epub 2014 Sep 19. PubMed PMID: 25196543; PubMed Central PMCID: PMC4428331.

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Milner E, Holtzman JC, Friess S, Hartman RE, Brody DL, Han BH, Zipfel GJ. Endovascular perforation subarachnoid hemorrhage fails to cause Morris water maze deficits in the mouse. J Cereb Blood Flow Metab. 2014 Sep;34(9):1571-2. doi: 10.1038/jcbfm.2014.108. Epub 2014 Jun 18. PubMed PMID: 24938403; PubMed Central PMCID: PMC4158664.

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Ashwal S, Ghosh N, Turenius CI, Dulcich M, Denham CM, Tone B, Hartman R, Snyder EY, Obenaus A. Reparative effects of neural stem cells in neonatal rats with hypoxic-ischemic injury are not influenced by host sex. Pediatr Res. 2014 May;75(5):603-11. doi: 10.1038/pr.2014.7. Epub 2014 Jan 24. PubMed PMID: 24463490; PubMed Central PMCID: PMC4404035.

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Manaenko A, Lekic T, Barnhart M, Hartman R, Zhang JH. Inhibition of transforming growth factor-β attenuates brain injury and neurological deficits in a rat model of germinal matrix hemorrhage. Stroke. 2014 Mar;45(3):828-34. doi: 10.1161/STROKEAHA.113.003754. Epub 2014 Jan 14. PubMed PMID: 24425124; PubMed Central PMCID: PMC3966308.

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Kamper JE, Pop V, Fukuda AM, Ajao DO, Hartman RE, Badaut J. Juvenile traumatic brain injury evolves into a chronic brain disorder: behavioral and histological changes over 6months. Exp Neurol. 2013 Dec;250:8-19. doi: 10.1016/j.expneurol.2013.09.016. Epub 2013 Sep 25. PubMed PMID: 24076005; PubMed Central PMCID: PMC3895624.

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Ropacki SA, Patel SM, Hartman RE. Pomegranate Supplementation Protects against Memory Dysfunction after Heart Surgery: A Pilot Study. Evid Based Complement Alternat Med. 2013;2013:932401. doi: 10.1155/2013/932401. Epub 2013 Sep 16. PubMed PMID: 24159353; PubMed Central PMCID: PMC3789410.

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Fukuda AM, Adami A, Pop V, Bellone JA, Coats JS, Hartman RE, Ashwal S, Obenaus A, Badaut J. Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery. J Cereb Blood Flow Metab. 2013 Oct;33(10):1621-32. doi: 10.1038/jcbfm.2013.118. Epub 2013 Jul 31. PubMed PMID: 23899928; PubMed Central PMCID: PMC3790933.

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Lekic T, Rolland W, Krafft PR, Suzuki H, Tang J, Zhang JH, Kamper JE, Hartman RE. Response. J Neurosurg. 2013 May;118(5):1152-3. PubMed PMID: 23776937.

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Dulcich MS, Hartman RE. Pomegranate supplementation improves affective and motor behavior in mice after radiation exposure. Evid Based Complement Alternat Med. 2013;2013:940830. doi: 10.1155/2013/940830. Epub 2013 Apr 15. PubMed PMID: 23662154; PubMed Central PMCID: PMC3639646.

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Obenaus A, Huang L, Coats JS, Hartman RE, Badaut J, Ashwal S. Animal models. In: Kirkwood MW, Yeates KO, editors. Mild Traumatic Brain Injury in Children and Adolescents: From Basic Science to Clinical Management USA: The Guilford Press; 2012.

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Huang L, Coats JS, Mohd-Yusof A, Yin Y, Assaad S, Muellner MJ, Kamper JE, Hartman RE, Dulcich M, Donovan VM, Oyoyo U, Obenaus A. Tissue vulnerability is increased following repetitive mild traumatic brain injury in the rat. Brain Res. 2013 Mar 7;1499:109-20. doi: 10.1016/j.brainres.2012.12.038. Epub 2012 Dec 28. PubMed PMID: 23276495.

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Rolland WB, Lekic T, Krafft PR, Hasegawa Y, Altay O, Hartman R, Ostrowski R, Manaenko A, Tang J, Zhang JH. Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage. Exp Neurol. 2013 Mar;241:45-55. doi: 10.1016/j.expneurol.2012.12.009. Epub 2012 Dec 21. PubMed PMID: 23261767; PubMed Central PMCID: PMC3570752.

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Lekic T, Rolland W, Manaenko A, Krafft PR, Kamper JE, Suzuki H, Hartman RE, Tang J, Zhang JH. Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage. J Neurosurg. 2013 Feb;118(2):465-77. doi: 10.3171/2012.10.JNS111836. Epub 2012 Nov 30. PubMed PMID: 23198805; PubMed Central PMCID: PMC3569075.

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Pop V, Sorensen DW, Kamper JE, Ajao DO, Murphy MP, Head E, Hartman RE, Badaut J. Early brain injury alters the blood-brain barrier phenotype in parallel with β-amyloid and cognitive changes in adulthood. J Cereb Blood Flow Metab. 2013 Feb;33(2):205-14. doi: 10.1038/jcbfm.2012.154. Epub 2012 Nov 14. PubMed PMID: 23149553; PubMed Central PMCID: PMC3564189.