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Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC. Biophysical journal. . NIHMSID: NIHMS891991.
Tang P, Colflesh DE, Chu B. Temperature effect on fractal structure of silica aggregates. J Colloid Interf Sci. 1988 November; 126(1):304-313. doi: Doi 10.1016/0021-9797(88)90124-5.
Tang P, Santos RA, Harbison GS. Two-dimensional solid-state NMR studies of the conformation of oriented DNA. Advances in Magnetic Resonance. 1989; 13:225- 255.
Santos RA, Tang P, Harbison GS. Determination of the DNA sugar pucker using 13C NMR spectroscopy. Biochemistry. 1989 Nov 28;28(24):9372-8. doi: 10.1021/bi00450a018. PubMed PMID: 2611236.
Santos RA, Tang P, Chien WJ, Kwan S, Harbison GS. NMR resolution of a crystallographic controversy 14N single crystal studies of silver, barium and lead nitrate. The Journal of physical chemistry. 1990; 94:2717-2721.
Tang P, Juang CL, Harbison GS. Intercalation complex of proflavine with DNA: structure and dynamics by solid-state NMR. Science. 1990 Jul 6;249(4964):70-2. doi: 10.1126/science.2367853. PubMed PMID: 2367853.
Raftery D, Long H, Reven L, Tang P, Pines A. NMR of optically pumped xenon thin films. Chemical physics letters. 1992; 191(5):385-390. doi: Doi 10.1016/0009-2614(92)85396-R.
Raftery D, Long H, Reven L, Tang P, Reimer JA, Pines A. Spin polarized 129Xe NMR study of a polymer surface. The Journal of physical chemistry. 1993; 97:1649-1655. doi: 10.1021/j100110a029.
Long H, Gaede HC, Shore J, Reven L, Bowers CR, Kritzenberger J, Pietrass T, Pines A, Tang P, Reimer JA. High-field cross polarization NMR from laser-polarized xenon to a polymer surface. Journal of the American Chemical Society. 1993; 115:8491-8492. doi: 10.1021/ja00071a086.
Tang P, Denn MM, Reimer MA. Studies of microstructure and miscibility in vecta/PET blends by solid-state NMR. Macromolecules. 1993; 26:4269-4274.
Tang P, Chien WJ, Harbison GS. Double-resonance circuit for nuclear magnetic resonance spectroscopy. Solid State Nucl Magn Reson. 1993 Dec;2(6):343-8. doi: 10.1016/0926-2040(83)90006-1. PubMed PMID: 7812759.
Urban C, McCord EF, Webster OW, Abrams L, Tang P, Others. Xe-129 NMR Studies of Hyper-Cross-Linked Polyarylcarbinols-Rigid Versus Flexible Structures. Chemistry of materials : a publication of the American Chemical Society. 1995; 7:1325-1332.
Juang CL, Tang P, Harbison GS. Solid-state NMR of DNA. Methods Enzymol. 1995;261:256-70. doi: 10.1016/s0076-6879(95)61013-8. PubMed PMID: 8569498.
Hyde EG, Boyer A, Tang P, Xu Y, Abramson SN. Irreversible inhibitors of nicotinic acetylcholine receptors: isolation and structural characterization of the biologically active solvolysis products of bipinnatin-A and bipinnatin-C. J Med Chem. 1995 Jun 9;38(12):2231-8. doi: 10.1021/jm00012a023. PubMed PMID: 7783154.
Xu Y, Tang P, Zhang W, Firestone L, Winter PM. Fluorine-19 nuclear magnetic resonance imaging and spectroscopy of sevoflurane uptake, distribution, and elimination in rat brain. Anesthesiology. 1995 Oct;83(4):766-74. doi: 10.1097/00000542-199510000-00016. PubMed PMID: 7574056.
Xu Y, Tang P, Firestone L, Zhang TT. 19F nuclear magnetic resonance investigation of stereoselective binding of isoflurane to bovine serum albumin. Biophys J. 1996 Jan;70(1):532-8. doi: 10.1016/S0006-3495(96)79599-1. PubMed PMID: 8770230; PubMed Central PMCID: PMC1224952.
Bedu-Addo FK, Tang P, Xu Y, Huang L. Interaction of polyethyleneglycol-phospholipid conjugates with cholesterol-phosphatidylcholine mixtures: sterically stabilized liposome formulations. Pharm Res. 1996 May;13(5):718-24. doi: 10.1023/a:1016043431778. PubMed PMID: 8860426.
Xu Y, Tang P. Amphiphilic sites for general anesthetic action? Evidence from 129Xe-[1H] intermolecular nuclear Overhauser effects. Biochim Biophys Acta. 1997 Jan 14;1323(1):154-62. doi: 10.1016/s0005-2736(96)00184-8. PubMed PMID: 9030222.
Tang P, Yan B, Xu Y. Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study. Biophys J. 1997 Apr;72(4):1676-82. doi: 10.1016/S0006-3495(97)78813-1. PubMed PMID: 9083671; PubMed Central PMCID: PMC1184361.
Xu Y, Tang P. Easy fabrication of a tunable high-pass birdcage resonator. Magn Reson Med. 1997 Jul;38(1):168-72. doi: 10.1002/mrm.1910380123. PubMed PMID: 9211393.
Liachenko S, Tang P, Somogyi GT, Xu Y. Comparison of anaesthetic and non-anaesthetic effects on depolarization-evoked glutamate and GABA release from mouse cerebrocortical slices. Br J Pharmacol. 1998 Mar;123(6):1274-80. doi: 10.1038/sj.bjp.0701728. PubMed PMID: 9559915; PubMed Central PMCID: PMC1565278.
Liachenko S, Tang P, Hamilton RL, Xu Y. A reproducible model of circulatory arrest and remote resuscitation in rats for NMR investigation. Stroke. 1998 Jun;29(6):1229-38; discussion 1238-9. doi: 10.1161/01.str.29.6.1229. PubMed PMID: 9626299.
Tang P, Liachenko S, Melick JA, Xu Y. [31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices. Epilepsia. 1998 Jun;39(6):577-83. doi: 10.1111/j.1528-1157.1998.tb01424.x. PubMed PMID: 9637598.
Xu Y, Tang P, Liachenko S. Unifying characteristics of sites of anesthetic action revealed by combined use of anesthetics and non-anesthetics. Toxicol Lett. 1998 Nov 23;100-101:347-52. doi: 10.1016/s0378-4274(98)00205-7. Review. PubMed PMID: 10049163.
Tang P, Simplaceanu V, Xu Y. Structural consequences of anesthetic and nonimmobilizer interaction with gramicidin A channels. Biophys J. 1999 May;76(5):2346-50. doi: 10.1016/S0006-3495(99)77391-1. PubMed PMID: 10233053; PubMed Central PMCID: PMC1300208.
Liachenko S, Tang P, Somogyi GT, Xu Y. Concentration-dependent isoflurane effects on depolarization-evoked glutamate and GABA outflows from mouse brain slices. Br J Pharmacol. 1999 May;127(1):131-8. doi: 10.1038/sj.bjp.0702543. PubMed PMID: 10369465; PubMed Central PMCID: PMC1566008.
Tang P, Hu J, Liachenko S, Xu Y. Distinctly different interactions of anesthetic and nonimmobilizer with transmembrane channel peptides. Biophys J. 1999 Aug;77(2):739-46. doi: 10.1016/S0006-3495(99)76928-6. PubMed PMID: 10423422; PubMed Central PMCID: PMC1300368.
Xu Y, Seto T, Tang P, Firestone L. NMR study of volatile anesthetic binding to nicotinic acetylcholine receptors. Biophys J. 2000 Feb;78(2):746-51. doi: 10.1016/S0006-3495(00)76632-X. PubMed PMID: 10653787; PubMed Central PMCID: PMC1300677.
Zubrzycki IZ, Xu Y, Madrid M, Tang P. Molecular dynamics simulations of a fully hydrated dimyristoylphosphatidylcholine bilayer in liquid-crystalline phase. The Journal of chemical physics. 2000 February; 112(7):3437-3441.
Tang P, Eckenhoff RG, Xu Y. General anesthetic binding to gramicidin A: the structural requirements. Biophys J. 2000 Apr;78(4):1804-9. doi: 10.1016/S0006-3495(00)76730-0. PubMed PMID: 10733961; PubMed Central PMCID: PMC1300775.
Tang P, Zubrzycki IZ, Xu Y. Ab Initio Calculation of Structures and Properties of Halogenated General Anesthetics: Halothane and Sevoflurane. Journal of computational chemistry. 2001 February; 22(4):436-444. doi: 10.1002/1096-987X(200103)22:4<436::AID-JCC1014>3.0.CO;2-U.
Liachenko S, Tang P, Hamilton RL, Xu Y. Regional dependence of cerebral reperfusion after circulatory arrest in rats. J Cereb Blood Flow Metab. 2001 Nov;21(11):1320-9. doi: 10.1097/00004647-200111000-00008. PubMed PMID: 11702047.
Yushmanov VE, Wang L, Liachenko S, Tang P, Xu Y. ADC characterization of region-specific response to cerebral perfusion deficit in rats by MRI at 9.4 T. Magn Reson Med. 2002 Mar;47(3):562-70. doi: 10.1002/mrm.10103. PubMed PMID: 11870844.
Xu Y, Liachenko S, Tang P. Dependence of early cerebral reperfusion and long-term outcome on resuscitation efficiency after cardiac arrest in rats. Stroke. 2002 Mar;33(3):837-43. doi: 10.1161/hs0302.104198. PubMed PMID: 11872912.
Wang L, Yushmanov VE, Liachenko SM, Tang P, Hamilton RL, Xu Y. Late reversal of cerebral perfusion and water diffusion after transient focal ischemia in rats. J Cereb Blood Flow Metab. 2002 Mar;22(3):253-61. doi: 10.1097/00004647-200203000-00002. PubMed PMID: 11891430.
Xu Y, Yushmanov VE, Tang P. NMR studies of drug interaction with membranes and membrane-associated proteins. Biosci Rep. 2002 Apr;22(2):175-96. doi: 10.1023/a:1020182404940. Review. PubMed PMID: 12428900.
Tang P, Mandal PK, Xu Y. NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating. Biophys J. 2002 Jul;83(1):252-62. doi: 10.1016/S0006-3495(02)75166-7. PubMed PMID: 12080117; PubMed Central PMCID: PMC1302144.
Tang P, Mandal PK, Zegarra M. Effects of volatile anesthetic on channel structure of gramicidin A. Biophys J. 2002 Sep;83(3):1413-20. doi: 10.1016/S0006-3495(02)73912-X. PubMed PMID: 12202367; PubMed Central PMCID: PMC1302240.
Homanics GE, Xu Y, Tang P. Integrated approaches to the action of general anesthetics and alcohol. Physiol Behav. 2002 Dec;77(4-5):495-9. doi: 10.1016/s0031-9384(02)00910-1. Review. PubMed PMID: 12526989.
Tang P, Xu Y. Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16035-40. doi: 10.1073/pnas.252522299. Epub 2002 Nov 18. PubMed PMID: 12438684; PubMed Central PMCID: PMC138560.
Yushmanov VE, Mandal PK, Liu Z, Tang P, Xu Y. NMR structure and backbone dynamics of the extended second transmembrane domain of the human neuronal glycine receptor alpha1 subunit. Biochemistry. 2003 Apr 8;42(13):3989-95. doi: 10.1021/bi026767g. PubMed PMID: 12667090.
Liachenko S, Tang P, Xu Y. Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats. J Cereb Blood Flow Metab. 2003 May;23(5):574-81. doi: 10.1097/01.WCB.0000057742.00152.3F. PubMed PMID: 12771572.
Yushmanov VE, Xu Y, Tang P. NMR structure and dynamics of the second transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit. Biochemistry. 2003 Nov 11;42(44):13058-65. doi: 10.1021/bi0350396. PubMed PMID: 14596621.
Liu Z, Xu Y, Saladino AC, Wymore T, Tang P. Parameterization of 2-Bromo-2-Chloro-1,1,1-Trifluoroethane (Halothane) and Hexafluoroethane for Nonbonded Interactions. The journal of physical chemistry. A. 2004; 108:781-786.
Saladino AC, Tang P. Optimization of Structures and LJ Parameters of 1-Chloro-1,2,2,-Trifluorocyclobutane and 1,2-Dichlorohexafluorocyclobutane. The journal of physical chemistry. A. 2004; 108:10560-10564.
Saladino AC, Xu Y, Tang P. Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor. Biophys J. 2005 Feb;88(2):1009-17. doi: 10.1529/biophysj.104.053421. Epub 2004 Dec 1. PubMed PMID: 15574706; PubMed Central PMCID: PMC1305108.
Liu Z, Xu Y, Tang P. Molecular dynamics simulations of C2F6 effects on gramicidin A: implications of the mechanisms of general anesthesia. Biophys J. 2005 Jun;88(6):3784-91. doi: 10.1529/biophysj.104.055566. Epub 2005 Mar 11. PubMed PMID: 15764669; PubMed Central PMCID: PMC1305613.
Ma D, Liu Z, Li L, Tang P, Xu Y. Structure and dynamics of the second and third transmembrane domains of human glycine receptor. Biochemistry. 2005 Jun 21;44(24):8790-800. doi: 10.1021/bi050256n. PubMed PMID: 15952785.
Li L, Geng X, Yonkunas M, Su A, Densmore E, Tang P, Drain P. Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channel. J Gen Physiol. 2005 Sep;126(3):285-99. doi: 10.1085/jgp.200509289. PubMed PMID: 16129775; PubMed Central PMCID: PMC2266580.
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