My Bibliography

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Muppirala AN, Rao M. Isolation of Distinct Populations of Enteric Glia from the Muscularis Externa and Mucosa of the Mouse Intestine. Methods Mol Biol. 2026;2971:43-53. doi: 10.1007/978-1-0716-4795-0_5. PubMed PMID: 41028623.

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Lagomarsino VN, Robinson A, Mitchell PE, Jiang M, Hutchinson LE, Sekela JJ, Caron P, Gehris MK, Navas KI, Duarte-Silva M, Netherland M Jr, Hasan NA, Guillemette C, Redinbo MR, Rao M. Microbial reactivation of host androgens directs enteric neuronal regulation of gut motility. Nat Neurosci. 2026 Aug;29(8):1791-1800. doi: 10.1038/s41593-026-02321-0. Epub 2026 Jun 2. PubMed PMID: 42231021; PubMed Central PMCID: PMC13403785.

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Cheng YT, MacKinnon-Booth N, Jiao Y, Robbins JR, Duarte-Silva M, Mitchell PE, Liu Y, Barkai O, Heo K, Zhang B, Lenfers Turnes B, Rao M, Woolf CJ. Colitis-induced visceral pain recruits central neurotensin neurons that modulate colonic sensitivity. bioRxiv. 2026 Mar 2;. doi: 10.64898/2026.02.27.708254. PubMed PMID: 41867832; PubMed Central PMCID: PMC13001329.

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Muppirala AN, Mitchell PE, Courtney E, Debnath S, D'Alessandro LR, Mani N, Dadabhoy M, Robinson A, Díaz-Muñoz C, Paraskevopoulou MD, D'Amato M, Gould TW, Rao M. Tachykinin signaling defines distinct populations of glia in the enteric nervous system. Neuron. 2026 Mar 18;114(6):1066-1082.e8. doi: 10.1016/j.neuron.2025.11.030. Epub 2026 Jan 8. PubMed PMID: 41512855; PubMed Central PMCID: PMC12832054.

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Chen X, Raghunathan K, Bao B, Ngwa E, Kwong A, Wu Z, Babcock S, Baek C, Ye G, Muppirala A, Peng Q, Rutlin M, Bhaumik M, Yang D, Kotlarz D, Jadhav U, Rao M, Weerapana E, Zhou X, Ordovas-Montanes J, Snapper SB, Thiagarajah JR. A niche-dependent redox rheostat regulates epithelial stem cell fate. Nat Commun. 2025 Nov 28;16(1):11713. doi: 10.1038/s41467-025-66636-5. PubMed PMID: 41315209; PubMed Central PMCID: PMC12754055.

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Barilla RM, Berard C, Sun L, Sandhu S, Zaghouani S, Iyer KS, Altun G, Su CW, Deguine J, Singh V, Hou Y, Kusumakar K, Rutlin ML, Rao M, Zaghouani H, Shi HN, Xavier RJ, Kuchroo VK. Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense. Science. 2025 Jul 17;389(6757):260-267. doi: 10.1126/science.adn9850. Epub 2025 May 22. PubMed PMID: 40403128; PubMed Central PMCID: PMC12632183.

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Duarte-Silva M, Rao M. A gut-wrenching tale of neuronal distress. Neuron. 2025 May 7;113(9):1291-1293. doi: 10.1016/j.neuron.2025.03.033. PubMed PMID: 40339562.

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Prochera A, Muppirala AN, Kuziel GA, Soualhi S, Shepherd A, Sun L, Issac B, Rosenberg HJ, Karim F, Perez K, Smith KH, Archibald TH, Rakoff-Nahoum S, Hagen SJ, Rao M. Enteric glia regulate Paneth cell secretion and intestinal microbial ecology. Elife. 2025 Apr 14;13. doi: 10.7554/eLife.97144. PubMed PMID: 40227232; PubMed Central PMCID: PMC11996175.

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Rao M, Gulbransen BD. Enteric Glia. Cold Spring Harb Perspect Biol. 2025 Apr 1;17(4). doi: 10.1101/cshperspect.a041368. Review. PubMed PMID: 38951022; PubMed Central PMCID: PMC11960695.

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Debnath S, Heredia DJ, Procacci NM, Fedi C, Ni Bhraonain EP, Cobine CA, Gould TW. Enteric Neuronal Substrates Underlying Spontaneous and Evoked Neurogenic Contractions in Mouse Colon. Cell Mol Gastroenterol Hepatol. 2025;19(5):101462. doi: 10.1016/j.jcmgh.2025.101462. Epub 2025 Jan 13. PubMed PMID: 39814102; PubMed Central PMCID: PMC11937701.

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Nowak-Wegrzyn A, Sicherer SH, Akin C, Anvari S, Bartnikas LM, Berin MC, Bingemann TA, Boyd S, Brown-Whitehorn T, Bunyavanich S, Cianferoni A, du Toit G, Fortunato JE, Goldsmith JD, Groetch M, Leonard SA, Rao M, Schultz F, Schwaninger JM, Venter C, Westcott-Chavez A, Wood RA, Togias A. Current status and future directions in food protein-induced enterocolitis syndrome: An NIAID workshop report of the June 22, 2022, virtual meeting. J Allergy Clin Immunol. 2025 Feb;155(2):336-356. doi: 10.1016/j.jaci.2024.10.022. Epub 2024 Nov 7. PubMed PMID: 39521282; NIHMSID:NIHMS2034729.

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Shepherd A, Rao M. Reply. Gastroenterology. 2024 Aug;167(3):630-631. doi: 10.1053/j.gastro.2024.05.001. Epub 2024 May 9. PubMed PMID: 38734213.

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Shepherd A, Feinstein L, Sabel S, Rastelli D, Mezhibovsky E, Matthews L, Muppirala A, Robinson A, Sharma KR, ElSeht A, Zeve D, Breault DT, Gershon MD, Rao M. RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release From Enteroendocrine Cells. Gastroenterology. 2024 Mar;166(3):437-449. doi: 10.1053/j.gastro.2023.11.020. Epub 2023 Nov 21. PubMed PMID: 37995867; PubMed Central PMCID: PMC10922887.

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Manion J, Musser MA, Kuziel GA, Liu M, Shepherd A, Wang S, Lee PG, Zhao L, Zhang J, Marreddy RKR, Goldsmith JD, Yuan K, Hurdle JG, Gerhard R, Jin R, Rakoff-Nahoum S, Rao M, Dong M. C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation. Nature. 2023 Oct;622(7983):611-618. doi: 10.1038/s41586-023-06607-2. Epub 2023 Sep 12. PubMed PMID: 37699522; PubMed Central PMCID: PMC11188852.

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Prochera A, Rao M. Mini-Review: Enteric glial regulation of the gastrointestinal epithelium. Neurosci Lett. 2023 May 14;805:137215. doi: 10.1016/j.neulet.2023.137215. Epub 2023 Mar 30. Review. PubMed PMID: 37001854; PubMed Central PMCID: PMC10125724.

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Good PI, Li L, Hurst HA, Serrano Herrera I, Xu K, Rao M, Bateman DA, Al-Awqati Q, D'Agati VD, Costantini F, Lin F. Low nephron endowment increases susceptibility to renal stress and chronic kidney disease. JCI Insight. 2023 Feb 8;8(3). doi: 10.1172/jci.insight.161316. PubMed PMID: 36626229; PubMed Central PMCID: PMC9977438.

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Amy Shepherd, Laurence Feinstein, Svetlana Sabel, Daniella Rastelli, Esther Mezhibovsky, Lynley Matthews, Anoohya Muppirala, Ariel Robinson, Michael D. Gershon, Meenakshi Rao. RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release from Enteroendocrine Cells. 2022 April. DOI: 10.1101/2022.04.15.488514.

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Chalazonitis A, Rao M, Sulzer D. Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson's disease. NPJ Parkinsons Dis. 2022 Apr 22;8(1):50. doi: 10.1038/s41531-022-00308-9. Review. PubMed PMID: 35459867; PubMed Central PMCID: PMC9033791.

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Middelhoff M, Valenti G, Tomassoni L, Ochiai Y, Belin B, Takahashi R, Malagola E, Nienhüser H, Finlayson M, Hayakawa Y, Zamechek LB, Renz BW, Westphalen CB, Quante M, Margolis KG, Sims PA, Laise P, Califano A, Rao M, Gershon MD, Wang TC. Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury. Am J Physiol Gastrointest Liver Physiol. 2022 Jun 1;322(6):G583-G597. doi: 10.1152/ajpgi.00244.2021. Epub 2022 Mar 23. PubMed PMID: 35319286; PubMed Central PMCID: PMC9109794.

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Rastelli D, Robinson A, Lagomarsino VN, Matthews LT, Hassan R, Perez K, Dan W, Yim PD, Mixer M, Prochera A, Shepherd A, Sun L, Hall K, Ballou S, Lembo A, Nee J, Rao M. Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice. J Clin Invest. 2022 Jan 18;132(2). doi: 10.1172/JCI150789. PubMed PMID: 34847080; PubMed Central PMCID: PMC8759776.

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Wang RS, Lembo AJ, Kaptchuk TJ, Cheng V, Nee J, Iturrino J, Rao M, Loscalzo J, Silvester JA, Hall KT. Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome. Front Pain Res (Lausanne). 2021;2:775386. doi: 10.3389/fpain.2021.775386. eCollection 2021. PubMed PMID: 35295415; PubMed Central PMCID: PMC8915627.

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Dan W, Park GH, Vemaraju S, Wu AD, Perez K, Rao M, Berkowitz DE, Lang RA, Yim PD. Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3. Front Physiol. 2021;12:744294. doi: 10.3389/fphys.2021.744294. eCollection 2021. PubMed PMID: 34975518; PubMed Central PMCID: PMC8716924.

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Rao M, Bogunovic M. Enteric glia worm their way into gut immunity. Immunity. 2021 Dec 14;54(12):2698-2700. doi: 10.1016/j.immuni.2021.11.014. PubMed PMID: 34910939.

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Arbizu RA, Rao M. Raising the Bar on Translational Studies to Test the Neurobehavioral Effects of Laxatives. J Pediatr Gastroenterol Nutr. 2021 Oct 1;73(4):427-428. doi: 10.1097/MPG.0000000000003223. PubMed PMID: 34238827; PubMed Central PMCID: PMC8509632.

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Rosenberg HJ, Rao M. Enteric glia in homeostasis and disease: From fundamental biology to human pathology. iScience. 2021 Aug 20;24(8):102863. doi: 10.1016/j.isci.2021.102863. eCollection 2021 Aug 20. Review. PubMed PMID: 34401661; PubMed Central PMCID: PMC8348155.

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Yan Y, Ramanan D, Rozenberg M, McGovern K, Rastelli D, Vijaykumar B, Yaghi O, Voisin T, Mosaheb M, Chiu I, Itzkovitz S, Rao M, Mathis D, Benoist C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. Immunity. 2021 Mar 9;54(3):499-513.e5. doi: 10.1016/j.immuni.2021.02.002. PubMed PMID: 33691135; PubMed Central PMCID: PMC8133394.

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Rutlin M, Rastelli D, Kuo WT, Estep JA, Louis A, Riccomagno MM, Turner JR, Rao M. The Villin1 Gene Promoter Drives Cre Recombinase Expression in Extraintestinal Tissues. Cell Mol Gastroenterol Hepatol. 2020;10(4):864-867.e5. doi: 10.1016/j.jcmgh.2020.05.009. Epub 2020 May 25. PubMed PMID: 32464312; PubMed Central PMCID: PMC7573669.

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Chalazonitis A, Li Z, Pham TD, Chen J, Rao M, Lindholm P, Saarma M, Lindahl M, Gershon MD. Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit. J Comp Neurol. 2020 Oct;528(14):2420-2444. doi: 10.1002/cne.24901. Epub 2020 Mar 26. PubMed PMID: 32154930; PubMed Central PMCID: PMC7724936.

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Rao M. An increasingly complex view of intestinal motility. Nat Rev Gastroenterol Hepatol. 2020 Feb;17(2):72-73. doi: 10.1038/s41575-019-0249-0. Review. PubMed PMID: 31811278.

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Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020 Jan 9;180(1):33-49.e22. doi: 10.1016/j.cell.2019.11.014. Epub 2019 Dec 5. PubMed PMID: 31813624; PubMed Central PMCID: PMC6954329.

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Lindahl M, Chalazonitis A, Palm E, Pakarinen E, Danilova T, Pham TD, Setlik W, Rao M, Võikar V, Huotari J, Kopra J, Andressoo JO, Piepponen PT, Airavaara M, Panhelainen A, Gershon MD, Saarma M. Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice. Neurobiol Dis. 2020 Feb;134:104696. doi: 10.1016/j.nbd.2019.104696. Epub 2019 Nov 26. PubMed PMID: 31783118; PubMed Central PMCID: PMC7000201.

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Jazayeri A, Nonga D, Rao M. The Key to a Boy's Heart Is Through His Intestine. Gastroenterology. 2020 Apr;158(5):1226-1228. doi: 10.1053/j.gastro.2019.08.056. Epub 2019 Sep 24. PubMed PMID: 31560902.

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Russell JP, Mohammadi E, Ligon CO, Johnson AC, Gershon MD, Rao M, Shen Y, Chan CC, Eidam HS, DeMartino MP, Cheung M, Oliff AI, Kumar S, Greenwood-Van Meerveld B. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity. J Pharmacol Exp Ther. 2019 Feb;368(2):299-307. doi: 10.1124/jpet.118.252973. Epub 2018 Nov 9. PubMed PMID: 30413627; PubMed Central PMCID: PMC6346376.

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Kulkarni S, Ganz J, Bayrer J, Becker L, Bogunovic M, Rao M. Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease. J Neurosci. 2018 Oct 31;38(44):9346-9354. doi: 10.1523/JNEUROSCI.1663-18.2018. Review. PubMed PMID: 30381426; PubMed Central PMCID: PMC6209840.

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Rao M, Gershon MD. Enteric nervous system development: what could possibly go wrong?. Nat Rev Neurosci. 2018 Sep;19(9):552-565. doi: 10.1038/s41583-018-0041-0. Review. PubMed PMID: 30046054; PubMed Central PMCID: PMC6261281.

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Chalazonitis A, Rao M. Enteric nervous system manifestations of neurodegenerative disease. Brain Res. 2018 Aug 15;1693(Pt B):207-213. doi: 10.1016/j.brainres.2018.01.011. Epub 2018 Jan 31. Review. PubMed PMID: 29360466; PubMed Central PMCID: PMC6003851.

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Belin B, Rastelli D, Borrell J, Rao M. CGRPα expression defines a novel subset of putative intrinsic primary afferent neurons in the enteric nervous system. Gastroenterology. 2017; 150(4):S931.

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Sabel S, Rao M. Role of extrinsic and intrinsic nervous system. In: Waasdorp Hurtado C, Li B, editors. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition 2nd ed. Ambler, PA: NASPGHAN; 2017.

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Rao M, Rastelli D, Dong L, Chiu S, Setlik W, Gershon MD, Corfas G. Enteric Glia Regulate Gastrointestinal Motility but Are Not Required for Maintenance of the Epithelium in Mice. Gastroenterology. 2017 Oct;153(4):1068-1081.e7. doi: 10.1053/j.gastro.2017.07.002. Epub 2017 Jul 13. PubMed PMID: 28711628; PubMed Central PMCID: PMC5623141.

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Rao M, Gershon MD. Neurogastroenterology: The dynamic cycle of life in the enteric nervous system. Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):453-454. doi: 10.1038/nrgastro.2017.85. Epub 2017 Jun 28. PubMed PMID: 28655880.

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Sabel S, Rastelli D, Russell J, Kumar S, Gershon MD, Rao M. Ret receptor tyrosine kinase plays a sexually dimorphic role in the regulation of gastrointestinal motility and is expressed by distinct subsets of enteric neurons important for peristalsis. Gastroenterology. 2016; 150(4):S344.

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Rao M, Gershon MD. The bowel and beyond: the enteric nervous system in neurological disorders. Nat Rev Gastroenterol Hepatol. 2016 Sep;13(9):517-28. doi: 10.1038/nrgastro.2016.107. Epub 2016 Jul 20. Review. PubMed PMID: 27435372; PubMed Central PMCID: PMC5005185.

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Sabel S, Rastelli D, Russell J, Kumar S, Gershon M, Rao M. Sa1681 Ret Receptor Tyrosine Kinase Plays a Sexually Dimorphic Role in the Regulation of Gastrointestinal Motility and Is Expressed by Distinct Subsets of Enteric Neurons Important for Peristalsis. Gastroenterology. 2016 April; 150(4):S344-S345. doi: 10.1016/S0016-5085(16)31210-0.

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Rao M, Nelms BD, Dong L, Salinas-Rios V, Rutlin M, Gershon MD, Corfas G. Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system. Glia. 2015 Nov;63(11):2040-2057. doi: 10.1002/glia.22876. Epub 2015 Jun 29. PubMed PMID: 26119414; PubMed Central PMCID: PMC4695324.

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Tomer G, Xanthakos S, Kim S, Rao M, Book L, Litman HJ, Fishman LN. Perceptions of gender equality in work-life balance, salary, promotion, and harassment: results of the NASPGHAN task force survey. J Pediatr Gastroenterol Nutr. 2015 Apr;60(4):481-5. doi: 10.1097/MPG.0000000000000637. PubMed PMID: 25419680.

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Rao M, Gershon MD. Bugs, guts, and glia: how microbiota influence enteric gliogenesis and migration. Neuron. 2015 Jan 21;85(2):229-30. doi: 10.1016/j.neuron.2014.12.066. PubMed PMID: 25611502; PubMed Central PMCID: PMC4420734.

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Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC. Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. PubMed PMID: 25594183; PubMed Central PMCID: PMC4436082.

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Srinath A, Rao M, Husain SZ. New NASPGHAN research agenda to target the public. J Pediatr Gastroenterol Nutr. 2014 Feb;58(2):142-3. doi: 10.1097/MPG.0000000000000230. PubMed PMID: 24458217.

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Rao M, Nurko S. Motility Testing. In: Sondheimer J, Waasdorp-Hurtado C, editors. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition New York: Castle Connolly Graduate Medical Publishing; 2011. 465-468p.

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Rao M, Nurko S. Motility Testing. In: Sondheimer J, Waasdorp-Hurtado C, editors. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition New York: Castle Connolly Graduate Medical Publishing; 2011. p.465-468.