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Knudsen GM, Ganz M, Appelhoff S, Boellaard R, Bormans G, Carson RE, Catana C, Doudet D, Gee AD, Greve DN, Gunn RN, Halldin C, Herscovitch P, Huang H, Keller SH, Lammertsma AA, Lanzenberger R, Liow JS, Lohith TG, Lubberink M, Lyoo CH, Mann JJ, Matheson GJ, Nichols TE, Nørgaard M, Ogden T, Parsey R, Pike VW, Price J, Rizzo G, Rosa-Neto P, Schain M, Scott PJ, Searle G, Slifstein M, Suhara T, Talbot PS, Thomas A, Veronese M, Wong DF, Yaqub M, Zanderigo F, Zoghbi S, Innis RB. Guidelines for the content and format of PET brain data in publications and archives: A consensus paper. J Cereb Blood Flow Metab. 2020 Aug;40(8):1576-1585. doi: 10.1177/0271678X20905433. Epub 2020 Feb 16. PubMed PMID: 32065076; PubMed Central PMCID: PMC7370374.
Girgis RR, Forbes A, Abi-Dargham A, Slifstein M. A positron emission tomography occupancy study of brexpiprazole at dopamine D2 and D3 and serotonin 5-HT1A and 5-HT2A receptors, and serotonin reuptake transporters in subjects with schizophrenia. Neuropsychopharmacology. 2020 Apr;45(5):786-792. doi: 10.1038/s41386-019-0590-6. Epub 2019 Dec 17. PubMed PMID: 31847007; PubMed Central PMCID: PMC7075883.
Rutherford BR, Choi J, Slifstein M, O'Boyle K, Abi-Dargham A, Brown PJ, Wall MW, Vanegas-Arroyave N, Sakhardande J, Stern Y, Roose SP. Neuroanatomical predictors of L-DOPA response in older adults with psychomotor slowing and depression: A pilot study. J Affect Disord. 2020 Mar 15;265:439-444. doi: 10.1016/j.jad.2020.01.066. Epub 2020 Jan 15. PubMed PMID: 32090770; PubMed Central PMCID: PMC7042346.
Whitton AE, Reinen JM, Slifstein M, Ang YS, McGrath PJ, Iosifescu DV, Abi-Dargham A, Pizzagalli DA, Schneier FR. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain. 2020 Feb 1;143(2):701-710. doi: 10.1093/brain/awaa002. PubMed PMID: 32040562; PubMed Central PMCID: PMC7009463.
Slifstein M, Abi-Dargham A, Girgis RR, Suckow RF, Cooper TB, Divgi CR, Sokoloff P, Leriche L, Carberry P, Oya S, Joseph SK, Guiraud M, Montagne A, Brunner V, Gaudoux F, Tonner F. Binding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy subjects with [11C]-(+)-PHNO. Psychopharmacology (Berl). 2020 Feb;237(2):519-527. doi: 10.1007/s00213-019-05387-w. Epub 2019 Nov 26. PubMed PMID: 31773210.
Wai JM, Grassetti A, Slifstein M, Matuskey D, Nabulsi N, Ropchan J, Labaree D, Huang Y, Martinez D. Binge alcohol use is not associated with alterations in striatal dopamine receptor binding or dopamine release. Drug Alcohol Depend. 2019 Dec 1;205:107627. doi: 10.1016/j.drugalcdep.2019.107627. Epub 2019 Oct 17. PubMed PMID: 31669800; PubMed Central PMCID: PMC6893096.
Martinez D, Slifstein M, Matuskey D, Nabulsi N, Zheng MQ, Lin SF, Ropchan J, Urban N, Grassetti A, Chang D, Salling M, Foltin R, Carson RE, Huang Y. Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study. Neuropsychopharmacology. 2019 Sep;44(10):1720-1727. doi: 10.1038/s41386-019-0398-4. Epub 2019 Apr 26. PubMed PMID: 31026862; PubMed Central PMCID: PMC6785004.
Rutherford BR, Slifstein M, Chen C, Abi-Dargham A, Brown PJ, Wall MW, Vanegas-Arroyave N, Stern Y, Bailey V, Valente E, Roose SP. Effects of L-DOPA Monotherapy on Psychomotor Speed and [11C]Raclopride Binding in High-Risk Older Adults With Depression. Biol Psychiatry. 2019 Aug 1;86(3):221-229. doi: 10.1016/j.biopsych.2019.04.007. Epub 2019 Apr 15. PubMed PMID: 31178096; PubMed Central PMCID: PMC6641997.
Korner J, Cline GW, Slifstein M, Barba P, Rayat GR, Febres G, Leibel RL, Maffei A, Harris PE. A role for foregut tyrosine metabolism in glucose tolerance. Mol Metab. 2019 May;23:37-50. doi: 10.1016/j.molmet.2019.02.008. Epub 2019 Feb 27. PubMed PMID: 30876866; PubMed Central PMCID: PMC6479665.
Nørgaard M, Ganz M, Svarer C, Feng L, Ichise M, Lanzenberger R, Lubberink M, Parsey RV, Politis M, Rabiner EA, Slifstein M, Sossi V, Suhara T, Talbot PS, Turkheimer F, Strother SC, Knudsen GM. Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres. J Cereb Blood Flow Metab. 2019 Feb;39(2):210-222. doi: 10.1177/0271678X18770107. Epub 2018 Apr 13. PubMed PMID: 29651896; PubMed Central PMCID: PMC6365604.
Schneier FR, Slifstein M, Whitton AE, Pizzagalli DA, Reinen J, McGrath PJ, Iosifescu DV, Abi-Dargham A. Dopamine Release in Antidepressant-Naive Major Depressive Disorder: A Multimodal [11C]-(+)-PHNO Positron Emission Tomography and Functional Magnetic Resonance Imaging Study. Biol Psychiatry. 2018 Oct 15;84(8):563-573. doi: 10.1016/j.biopsych.2018.05.014. Epub 2018 May 25. PubMed PMID: 30041971; PubMed Central PMCID: PMC6347467.
Kegeles LS, Horga G, Ghazzaoui R, Rosengard R, Ojeil N, Xu X, Slifstein M, Petrakis I, O'Malley SS, Krystal JH, Abi-Dargham A. Enhanced Striatal Dopamine Release to Expectation of Alcohol: A Potential Risk Factor for Alcohol Use Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Jul;3(7):591-598. doi: 10.1016/j.bpsc.2018.03.018. Epub 2018 Apr 21. PubMed PMID: 29803635; PubMed Central PMCID: PMC6953614.
Weinstein JJ, van de Giessen E, Rosengard RJ, Xu X, Ojeil N, Brucato G, Gil RB, Kegeles LS, Laruelle M, Slifstein M, Abi-Dargham A. PET imaging of dopamine-D2 receptor internalization in schizophrenia. Mol Psychiatry. 2018 Jun;23(6):1506-1511. doi: 10.1038/mp.2017.107. Epub 2017 May 16. PubMed PMID: 28507321; PubMed Central PMCID: PMC5690884.
Slifstein M, Abi-Dargham A. Is it Pre- or Postsynaptic? Imaging Striatal Dopamine Excess in Schizophrenia. Biol Psychiatry. 2018 Apr 15;83(8):635-637. doi: 10.1016/j.biopsych.2018.02.015. PubMed PMID: 29559095.
Cassidy CM, Balsam PD, Weinstein JJ, Rosengard RJ, Slifstein M, Daw ND, Abi-Dargham A, Horga G. A Perceptual Inference Mechanism for Hallucinations Linked to Striatal Dopamine. Curr Biol. 2018 Feb 19;28(4):503-514.e4. doi: 10.1016/j.cub.2017.12.059. Epub 2018 Feb 2. PubMed PMID: 29398218; PubMed Central PMCID: PMC5820222.
Weinstein JJ, van de Giessen E, Rosengard RJ, Xu X, Ojeil N, Brucato G, Gil RB, Kegeles LS, Laruelle M, Slifstein M, Abi-Dargham A. PET imaging of dopamine-D2 receptor internalization in schizophrenia. Mol Psychiatry. 2017 Jul 25;. doi: 10.1038/mp.2017.157. [Epub ahead of print] PubMed PMID: 29155803.
van de Giessen E, Weinstein JJ, Cassidy CM, Haney M, Dong Z, Ghazzaoui R, Ojeil N, Kegeles LS, Xu X, Vadhan NP, Volkow ND, Slifstein M, Abi-Dargham A. Deficits in striatal dopamine release in cannabis dependence. Mol Psychiatry. 2017 Jan;22(1):68-75. doi: 10.1038/mp.2016.21. Epub 2016 Mar 22. PubMed PMID: 27001613; PubMed Central PMCID: PMC5033654.
Weinstein JJ, Chohan MO, Slifstein M, Kegeles LS, Moore H, Abi-Dargham A. Pathway-Specific Dopamine Abnormalities in Schizophrenia. Biol Psychiatry. 2017 Jan 1;81(1):31-42. doi: 10.1016/j.biopsych.2016.03.2104. Epub 2016 Mar 31. Review. PubMed PMID: 27206569; PubMed Central PMCID: PMC5177794.
Slifstein M, Abi-Dargham A. Recent Developments in Molecular Brain Imaging of Neuropsychiatric Disorders. Semin Nucl Med. 2017 Jan;47(1):54-63. doi: 10.1053/j.semnuclmed.2016.09.002. Epub 2016 Oct 13. Review. PubMed PMID: 27987558.
Van Snellenberg JX, Girgis RR, Horga G, van de Giessen E, Slifstein M, Ojeil N, Weinstein JJ, Moore H, Lieberman JA, Shohamy D, Smith EE, Abi-Dargham A. Mechanisms of Working Memory Impairment in Schizophrenia. Biol Psychiatry. 2016 Oct 15;80(8):617-26. doi: 10.1016/j.biopsych.2016.02.017. Epub 2016 Feb 23. PubMed PMID: 27056754; PubMed Central PMCID: PMC4995154.
Girgis RR, Slifstein M, D'Souza D, Lee Y, Periclou A, Ghahramani P, Laszlovszky I, Durgam S, Adham N, Nabulsi N, Huang Y, Carson RE, Kiss B, Kapás M, Abi-Dargham A, Rakhit A. Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [(11)C]-(+)-PHNO. Psychopharmacology (Berl). 2016 Oct;233(19-20):3503-12. doi: 10.1007/s00213-016-4382-y. Epub 2016 Aug 15. PubMed PMID: 27525990; PubMed Central PMCID: PMC5035321.
Horga G, Cassidy CM, Xu X, Moore H, Slifstein M, Van Snellenberg JX, Abi-Dargham A. Dopamine-Related Disruption of Functional Topography of Striatal Connections in Unmedicated Patients With Schizophrenia. JAMA Psychiatry. 2016 Aug 1;73(8):862-70. doi: 10.1001/jamapsychiatry.2016.0178. PubMed PMID: 27145361; PubMed Central PMCID: PMC5310843.
Girgis RR, Van Snellenberg JX, Glass A, Kegeles LS, Thompson JL, Wall M, Cho RY, Carter CS, Slifstein M, Abi-Dargham A, Lieberman JA. A proof-of-concept, randomized controlled trial of DAR-0100A, a dopamine-1 receptor agonist, for cognitive enhancement in schizophrenia. J Psychopharmacol. 2016 May;30(5):428-35. doi: 10.1177/0269881116636120. Epub 2016 Mar 10. PubMed PMID: 26966119.
Cassidy CM, Van Snellenberg JX, Benavides C, Slifstein M, Wang Z, Moore H, Abi-Dargham A, Horga G. Dynamic Connectivity between Brain Networks Supports Working Memory: Relationships to Dopamine Release and Schizophrenia. J Neurosci. 2016 Apr 13;36(15):4377-88. doi: 10.1523/JNEUROSCI.3296-15.2016. PubMed PMID: 27076432; PubMed Central PMCID: PMC4829655.
Gunn RN, Slifstein M, Searle GE, Price JC. Quantitative imaging of protein targets in the human brain with PET. Phys Med Biol. 2015 Nov 21;60(22):R363-411. doi: 10.1088/0031-9155/60/22/R363. Epub 2015 Oct 29. PubMed PMID: 26513176; NIHMSID:NIHMS735413.
Girgis RR, Xu X, Gil RB, Hackett E, Ojeil N, Lieberman JA, Slifstein M, Abi-Dargham A. Antipsychotic binding to the dopamine-3 receptor in humans: A PET study with [(11)C]-(+)-PHNO. Schizophr Res. 2015 Oct;168(1-2):373-6. doi: 10.1016/j.schres.2015.06.027. Epub 2015 Jul 17. PubMed PMID: 26190300; PubMed Central PMCID: PMC4591174.
Broft A, Slifstein M, Osborne J, Kothari P, Morim S, Shingleton R, Kenney L, Vallabhajosula S, Attia E, Martinez D, Timothy Walsh B. Striatal dopamine type 2 receptor availability in anorexia nervosa. Psychiatry Res. 2015 Sep 30;233(3):380-7. doi: 10.1016/j.pscychresns.2015.06.013. Epub 2015 Jul 26. PubMed PMID: 26272038; PubMed Central PMCID: PMC5055757.
Hwang DR, Hu E, Allen JR, Davis C, Treanor J, Miller S, Chen H, Shi B, Narayanan TK, Barret O, Alagille D, Yu Z, Slifstein M. Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18F]AMG 580 in non-human primates. Nucl Med Biol. 2015 Aug;42(8):654-63. doi: 10.1016/j.nucmedbio.2015.04.004. Epub 2015 Apr 16. PubMed PMID: 25935386.
Simpson HB, Kegeles LS, Hunter L, Mao X, Van Meter P, Xu X, Kimeldorf MB, Pearlstein SL, Slifstein M, Shungu DC. Assessment of glutamate in striatal subregions in obsessive-compulsive disorder with proton magnetic resonance spectroscopy. Psychiatry Res. 2015 Apr 30;232(1):65-70. doi: 10.1016/j.pscychresns.2015.01.009. Epub 2015 Feb 3. PubMed PMID: 25715904; PubMed Central PMCID: PMC4404189.
Van Snellenberg JX, Slifstein M, Read C, Weber J, Thompson JL, Wager TD, Shohamy D, Abi-Dargham A, Smith EE. Dynamic shifts in brain network activation during supracapacity working memory task performance. Hum Brain Mapp. 2015 Apr;36(4):1245-64. doi: 10.1002/hbm.22699. Epub 2014 Nov 24. PubMed PMID: 25422039; PubMed Central PMCID: PMC4722876.
Slifstein M, van de Giessen E, Van Snellenberg J, Thompson JL, Narendran R, Gil R, Hackett E, Girgis R, Ojeil N, Moore H, D'Souza D, Malison RT, Huang Y, Lim K, Nabulsi N, Carson RE, Lieberman JA, Abi-Dargham A. Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: a positron emission tomographic functional magnetic resonance imaging study. JAMA Psychiatry. 2015 Apr;72(4):316-24. doi: 10.1001/jamapsychiatry.2014.2414. PubMed PMID: 25651194; PubMed Central PMCID: PMC4768742.
Ridler K, Cunningham V, Huiban M, Martarello L, Pampols-Maso S, Passchier J, Gunn RN, Searle G, Abi-Dargham A, Slifstein M, Watson J, Laruelle M, Rabiner EA. An evaluation of the brain distribution of [(11)C]GSK1034702, a muscarinic-1 (M 1) positive allosteric modulator in the living human brain using positron emission tomography. EJNMMI Res. 2014 Dec;4(1):66. doi: 10.1186/s13550-014-0066-y. Epub 2014 Dec 5. PubMed PMID: 26116126; PubMed Central PMCID: PMC4452589.
van de Giessen E, Rosell DR, Thompson JL, Xu X, Girgis RR, Ehrlich Y, Slifstein M, Abi-Dargham A, Siever LJ. Serotonin transporter availability in impulsive aggressive personality disordered patients: a PET study with [11C]DASB. J Psychiatr Res. 2014 Nov;58:147-54. doi: 10.1016/j.jpsychires.2014.07.025. Epub 2014 Aug 6. PubMed PMID: 25145808.
Thompson JL, Rosell DR, Slifstein M, Girgis RR, Xu X, Ehrlich Y, Kegeles LS, Hazlett EA, Abi-Dargham A, Siever LJ. Prefrontal dopamine D1 receptors and working memory in schizotypal personality disorder: a PET study with [¹¹C]NNC112. Psychopharmacology (Berl). 2014 Oct;231(21):4231-40. doi: 10.1007/s00213-014-3566-6. Epub 2014 Apr 30. PubMed PMID: 24781514; PubMed Central PMCID: PMC4194223.
Luo SX, Martinez D, Carpenter KM, Slifstein M, Nunes EV. Multimodal predictive modeling of individual treatment outcome in cocaine dependence with combined neuroimaging and behavioral predictors. Drug Alcohol Depend. 2014 Oct 1;143:29-35. doi: 10.1016/j.drugalcdep.2014.04.030. Epub 2014 Jul 10. PubMed PMID: 25108585; PubMed Central PMCID: PMC4358761.
Hwang DR, Hu E, Rumfelt S, Easwaramoorthy B, Castrillon J, Davis C, Allen JR, Chen H, Treanor J, Abi-Dargham A, Slifstein M. Initial characterization of a PDE10A selective positron emission tomography tracer [11C]AMG 7980 in non-human primates. Nucl Med Biol. 2014 Apr;41(4):343-9. doi: 10.1016/j.nucmedbio.2014.01.007. Epub 2014 Jan 17. PubMed PMID: 24607437.
Martinez D, Slifstein M, Nabulsi N, Grassetti A, Urban NB, Perez A, Liu F, Lin SF, Ropchan J, Mao X, Kegeles LS, Shungu DC, Carson RE, Huang Y. Imaging glutamate homeostasis in cocaine addiction with the metabotropic glutamate receptor 5 positron emission tomography radiotracer [(11)C]ABP688 and magnetic resonance spectroscopy. Biol Psychiatry. 2014 Jan 15;75(2):165-71. doi: 10.1016/j.biopsych.2013.06.026. Epub 2013 Sep 12. PubMed PMID: 24035345; PubMed Central PMCID: PMC4106018.
Poels EM, Kegeles LS, Kantrowitz JT, Slifstein M, Javitt DC, Lieberman JA, Abi-Dargham A, Girgis RR. Imaging glutamate in schizophrenia: review of findings and implications for drug discovery. Mol Psychiatry. 2014 Jan;19(1):20-9. doi: 10.1038/mp.2013.136. Epub 2013 Oct 29. Review. PubMed PMID: 24166406.
Ravan S, Martinez D, Slifstein M, Abi-Dargham A. Molecular imaging in alcohol dependence. Handb Clin Neurol. 2014;125:293-311. doi: 10.1016/B978-0-444-62619-6.00018-5. Review. PubMed PMID: 25307582.
Comley RA, Salinas CA, Slifstein M, Petrone M, Marzano C, Bennacef I, Shotbolt P, Van der Aart J, Neve M, Iavarone L, Gomeni R, Laruelle M, Gray FA, Gunn RN, Rabiner EA. Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography. J Pharmacol Exp Ther. 2013 Aug;346(2):311-7. doi: 10.1124/jpet.112.202895. Epub 2013 May 17. PubMed PMID: 23685546.
Thompson JL, Urban N, Slifstein M, Xu X, Kegeles LS, Girgis RR, Beckerman Y, Harkavy-Friedman JM, Gil R, Abi-Dargham A. Striatal dopamine release in schizophrenia comorbid with substance dependence. Mol Psychiatry. 2013 Aug;18(8):909-15. doi: 10.1038/mp.2012.109. Epub 2012 Aug 7. PubMed PMID: 22869037; PubMed Central PMCID: PMC4128915.
Poels EM, Girgis RR, Thompson JL, Slifstein M, Abi-Dargham A. In vivo binding of the dopamine-1 receptor PET tracers [¹¹C]NNC112 and [¹¹C]SCH23390: a comparison study in individuals with schizophrenia. Psychopharmacology (Berl). 2013 Jul;228(1):167-74. doi: 10.1007/s00213-013-3026-8. Epub 2013 Mar 5. PubMed PMID: 23460265.
Simpson HB, Shungu DC, Bender J Jr, Mao X, Xu X, Slifstein M, Kegeles LS. Investigation of cortical glutamate-glutamine and γ-aminobutyric acid in obsessive-compulsive disorder by proton magnetic resonance spectroscopy. Neuropsychopharmacology. 2012 Nov;37(12):2684-92. doi: 10.1038/npp.2012.132. Epub 2012 Aug 1. PubMed PMID: 22850733; PubMed Central PMCID: PMC3473334.
Howes OD, Kambeitz J, Kim E, Stahl D, Slifstein M, Abi-Dargham A, Kapur S. The nature of dopamine dysfunction in schizophrenia and what this means for treatment. Arch Gen Psychiatry. 2012 Aug;69(8):776-86. doi: 10.1001/archgenpsychiatry.2012.169. PubMed PMID: 22474070; PubMed Central PMCID: PMC3730746.
Broft A, Shingleton R, Kaufman J, Liu F, Kumar D, Slifstein M, Abi-Dargham A, Schebendach J, Van Heertum R, Attia E, Martinez D, Walsh BT. Striatal dopamine in bulimia nervosa: a PET imaging study. Int J Eat Disord. 2012 Jul;45(5):648-56. doi: 10.1002/eat.20984. Epub 2012 Feb 13. PubMed PMID: 22331810; PubMed Central PMCID: PMC3640453.
Gallezot JD, Beaver JD, Gunn RN, Nabulsi N, Weinzimmer D, Singhal T, Slifstein M, Fowles K, Ding YS, Huang Y, Laruelle M, Carson RE, Rabiner EA. Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo. Synapse. 2012 Jun;66(6):489-500. doi: 10.1002/syn.21535. Epub 2012 Feb 24. PubMed PMID: 22213512.
Abi-Dargham A, Xu X, Thompson JL, Gil R, Kegeles LS, Urban N, Narendran R, Hwang DR, Laruelle M, Slifstein M. Increased prefrontal cortical D₁ receptors in drug naive patients with schizophrenia: a PET study with [¹¹C]NNC112. J Psychopharmacol. 2012 Jun;26(6):794-805. doi: 10.1177/0269881111409265. Epub 2011 Jul 18. PubMed PMID: 21768159.
Urban NB, Girgis RR, Talbot PS, Kegeles LS, Xu X, Frankle WG, Hart CL, Slifstein M, Abi-Dargham A, Laruelle M. Sustained recreational use of ecstasy is associated with altered pre and postsynaptic markers of serotonin transmission in neocortical areas: a PET study with [¹¹C]DASB and [¹¹C]MDL 100907. Neuropsychopharmacology. 2012 May;37(6):1465-73. doi: 10.1038/npp.2011.332. Epub 2012 Feb 22. PubMed PMID: 22353758; PubMed Central PMCID: PMC3327851.
Urban NB, Slifstein M, Meda S, Xu X, Ayoub R, Medina O, Pearlson GD, Krystal JH, Abi-Dargham A. Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging. Psychopharmacology (Berl). 2012 May;221(1):67-77. doi: 10.1007/s00213-011-2543-6. Epub 2011 Nov 4. PubMed PMID: 22052081.
Kegeles LS, Mao X, Stanford AD, Girgis R, Ojeil N, Xu X, Gil R, Slifstein M, Abi-Dargham A, Lisanby SH, Shungu DC. Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. Arch Gen Psychiatry. 2012 May;69(5):449-59. doi: 10.1001/archgenpsychiatry.2011.1519. Epub 2012 Jan 2. PubMed PMID: 22213769; NIHMSID:NIHMS352541.
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