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Wu S, Fagan RR, Uttamapinant C, Lifshitz LM, Fogarty KE, Ting AY, Melikian HE. The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach. J Neurosci. 2017 Sep 27;37(39):9438-9452. doi: 10.1523/JNEUROSCI.3885-16.2017. Epub 2017 Aug 28. PubMed PMID: 28847807; PubMed Central PMCID: PMC5618262.
Zheng K, Lu P, Delpapa E, Bellve K, Deng R, Condon JC, Fogarty K, Lifshitz LM, Simas TAM, Shi F, ZhuGe R. Bitter taste receptors as targets for tocolytics in preterm labor therapy. FASEB J. 2017 Sep;31(9):4037-4052. doi: 10.1096/fj.201601323RR. Epub 2017 May 30. PubMed PMID: 28559440; PubMed Central PMCID: PMC5572693.
Lu P, Zhang CH, Lifshitz LM, ZhuGe R. Extraoral bitter taste receptors in health and disease. J Gen Physiol. 2017 Feb;149(2):181-197. doi: 10.1085/jgp.201611637. Epub 2017 Jan 4. Review. PubMed PMID: 28053191; PubMed Central PMCID: PMC5299619.
Ly S, Navaroli DM, Didiot MC, Cardia J, Pandarinathan L, Alterman JF, Fogarty K, Standley C, Lifshitz LM, Bellve KD, Prot M, Echeverria D, Corvera S, Khvorova A. Visualization of self-delivering hydrophobically modified siRNA cellular internalization. Nucleic Acids Res. 2017 Jan 9;45(1):15-25. doi: 10.1093/nar/gkw1005. Epub 2016 Nov 28. PubMed PMID: 27899655; PubMed Central PMCID: PMC5224471.
Zhang CH, Wang P, Liu DH, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Lu P, Zheng K, Craige SM, Lifshitz LM, Keaney JF Jr, Fogarty KE, ZhuGe R, Zhu MS. The molecular basis of the genesis of basal tone in internal anal sphincter. Nat Commun. 2016 Apr 22;7:11358. doi: 10.1038/ncomms11358. PubMed PMID: 27101932; PubMed Central PMCID: PMC4844698.
Rojas-Rodriguez R, Lifshitz LM, Bellve KD, Min SY, Pires J, Leung K, Boeras C, Sert A, Draper JT, Corvera S, Moore Simas TA. Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus. Diabetologia. 2015 Sep;58(9):2106-14. doi: 10.1007/s00125-015-3662-0. Epub 2015 Jun 13. PubMed PMID: 26067361; PubMed Central PMCID: PMC4526585.
Rojas-Rodriguez R, Gealekman O, Kruse ME, Rosenthal B, Rao K, Min S, Bellve KD, Lifshitz LM, Corvera S. Adipose tissue angiogenesis assay. Methods Enzymol. 2014;537:75-91. doi: 10.1016/B978-0-12-411619-1.00005-7. PubMed PMID: 24480342; PubMed Central PMCID: PMC4386572.
Zhang CH, Lifshitz LM, Uy KF, Ikebe M, Fogarty KE, ZhuGe R. The cellular and molecular basis of bitter tastant-induced bronchodilation. PLoS Biol. 2013;11(3):e1001501. doi: 10.1371/journal.pbio.1001501. Epub 2013 Mar 5. PubMed PMID: 23472053; PubMed Central PMCID: PMC3589262.
Zhang CH, Li Y, Zhao W, Lifshitz LM, Li H, Harfe BD, Zhu MS, ZhuGe R. The transmembrane protein 16A Ca(2+)-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness. Am J Respir Crit Care Med. 2013 Feb 15;187(4):374-81. doi: 10.1164/rccm.201207-1303OC. Epub 2012 Dec 13. PubMed PMID: 23239156; PubMed Central PMCID: PMC3603598.
Zhang CH, Chen C, Lifshitz LM, Fogarty KE, Zhu MS, ZhuGe R. Activation of BK channels may not be required for bitter tastant-induced bronchodilation. Nat Med. 2012 May 4;18(5):648-50; author reply 650-1. doi: 10.1038/nm.2733. PubMed PMID: 22561814; NIHMSID:NIHMS660288.
Navaroli DM, Bellvé KD, Standley C, Lifshitz LM, Cardia J, Lambright D, Leonard D, Fogarty KE, Corvera S. Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):E471-80. doi: 10.1073/pnas.1115495109. Epub 2012 Jan 30. PubMed PMID: 22308388; PubMed Central PMCID: PMC3286945.
Navaroli DM, Stevens ZH, Uzelac Z, Gabriel L, King MJ, Lifshitz LM, Sitte HH, Melikian HE. The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter trafficking. J Neurosci. 2011 Sep 28;31(39):13758-70. doi: 10.1523/JNEUROSCI.2649-11.2011. PubMed PMID: 21957239; PubMed Central PMCID: PMC3205929.
Lifshitz LM, Carmichael JD, Lai FA, Sorrentino V, Bellvé K, Fogarty KE, ZhuGe R. Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes. J Gen Physiol. 2011 Aug;138(2):195-209. doi: 10.1085/jgp.201110626. Epub 2011 Jul 11. PubMed PMID: 21746845; PubMed Central PMCID: PMC3149436.
Jurczyk A, Pino SC, O'Sullivan-Murphy B, Addorio M, Lidstone EA, Diiorio P, Lipson KL, Standley C, Fogarty K, Lifshitz L, Urano F, Mordes JP, Greiner DL, Rossini AA, Bortell R. A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells. PLoS One. 2010 Jul 27;5(7):e11812. doi: 10.1371/journal.pone.0011812. PubMed PMID: 20676397; PubMed Central PMCID: PMC2910730.
Zhuge R, Bao R, Fogarty KE, Lifshitz LM. Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle. J Biol Chem. 2010 Jan 15;285(3):2203-10. doi: 10.1074/jbc.M109.067546. Epub 2009 Nov 17. PubMed PMID: 19920135; PubMed Central PMCID: PMC2804376.
Li X, Standley C, Sapp E, Valencia A, Qin ZH, Kegel KB, Yoder J, Comer-Tierney LA, Esteves M, Chase K, Alexander J, Masso N, Sobin L, Bellve K, Tuft R, Lifshitz L, Fogarty K, Aronin N, DiFiglia M. Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity. Mol Cell Biol. 2009 Nov;29(22):6106-16. doi: 10.1128/MCB.00420-09. Epub 2009 Sep 14. PubMed PMID: 19752198; PubMed Central PMCID: PMC2772576.
Lefkowitz JJ, Fogarty KE, Lifshitz LM, Bellve KD, Tuft RA, ZhuGe R, Walsh JV Jr, De Crescenzo V. Suppression of Ca2+ syntillas increases spontaneous exocytosis in mouse adrenal chromaffin cells. J Gen Physiol. 2009 Oct;134(4):267-80. doi: 10.1085/jgp.200910285. PubMed PMID: 19786582; PubMed Central PMCID: PMC2757764.
Leonard D, Hayakawa A, Lawe D, Lambright D, Bellve KD, Standley C, Lifshitz LM, Fogarty KE, Corvera S. Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes. J Cell Sci. 2008 Oct 15;121(Pt 20):3445-58. doi: 10.1242/jcs.031484. Epub 2008 Sep 30. PubMed PMID: 18827013; PubMed Central PMCID: PMC2586290.
Bao R, Lifshitz LM, Tuft RA, Bellvé K, Fogarty KE, ZhuGe R. A close association of RyRs with highly dense clusters of Ca2+-activated Cl- channels underlies the activation of STICs by Ca2+ sparks in mouse airway smooth muscle. J Gen Physiol. 2008 Jul;132(1):145-60. doi: 10.1085/jgp.200709933. PubMed PMID: 18591421; PubMed Central PMCID: PMC2442178.
Zhang YA, Tuft RA, Lifshitz LM, Fogarty KE, Singer JJ, Zou H. Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance. Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2448-61. doi: 10.1152/ajpheart.00032.2007. Epub 2007 May 4. PubMed PMID: 17483243.
Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S, Corvera S, Fogarty KE, Czech MP. Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes. Mol Cell Biol. 2007 May;27(9):3456-69. doi: 10.1128/MCB.01719-06. Epub 2007 Mar 5. PubMed PMID: 17339344; PubMed Central PMCID: PMC1899973.
Takizawa N, Smith TC, Nebl T, Crowley JL, Palmieri SJ, Lifshitz LM, Ehrhardt AG, Hoffman LM, Beckerle MC, Luna EJ. Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol. 2006 Jul 31;174(3):447-58. doi: 10.1083/jcb.200512051. PubMed PMID: 16880273; PubMed Central PMCID: PMC2064240.
De Crescenzo V, Fogarty KE, Zhuge R, Tuft RA, Lifshitz LM, Carmichael J, Bellvé KD, Baker SP, Zissimopoulos S, Lai FA, Lemos JR, Walsh JV Jr. Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals. J Neurosci. 2006 Jul 19;26(29):7565-74. doi: 10.1523/JNEUROSCI.1512-06.2006. PubMed PMID: 16855084; PubMed Central PMCID: PMC6674279.
Bellve KD, Leonard D, Standley C, Lifshitz LM, Tuft RA, Hayakawa A, Corvera S, Fogarty KE. Plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells. J Biol Chem. 2006 Jun 9;281(23):16139-46. doi: 10.1074/jbc.M511370200. Epub 2006 Mar 13. PubMed PMID: 16537543.
ZhuGe R, DeCrescenzo V, Sorrentino V, Lai FA, Tuft RA, Lifshitz LM, Lemos JR, Smith C, Fogarty KE, Walsh JV Jr. Syntillas release Ca2+ at a site different from the microdomain where exocytosis occurs in mouse chromaffin cells. Biophys J. 2006 Mar 15;90(6):2027-37. doi: 10.1529/biophysj.105.071654. Epub 2005 Dec 30. PubMed PMID: 16387759; PubMed Central PMCID: PMC1386781.
Politz JC, Tuft RA, Prasanth KV, Baudendistel N, Fogarty KE, Lifshitz LM, Langowski J, Spector DL, Pederson T. Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm. Mol Biol Cell. 2006 Mar;17(3):1239-49. doi: 10.1091/mbc.e05-10-0952. Epub 2005 Dec 21. PubMed PMID: 16371503; PubMed Central PMCID: PMC1382313.
Zhuge R, Fogarty KE, Baker SP, McCarron JG, Tuft RA, Lifshitz LM, Walsh JV Jr. Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them. Am J Physiol Cell Physiol. 2004 Dec;287(6):C1577-88. doi: 10.1152/ajpcell.00153.2004. Epub 2004 Aug 11. PubMed PMID: 15306542.
Huang S, Lifshitz L, Patki-Kamath V, Tuft R, Fogarty K, Czech MP. Phosphatidylinositol-4,5-bisphosphate-rich plasma membrane patches organize active zones of endocytosis and ruffling in cultured adipocytes. Mol Cell Biol. 2004 Oct;24(20):9102-23. doi: 10.1128/MCB.24.20.9102-9123.2004. PubMed PMID: 15456883; PubMed Central PMCID: PMC517906.
Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ. Using total fluorescence increase (signal mass) to determine the Ca2+ current underlying localized Ca2+ events. J Gen Physiol. 2004 Sep;124(3):259-72. doi: 10.1085/jgp.200409066. PubMed PMID: 15337821; PubMed Central PMCID: PMC2233884.
Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ. Imaging calcium entering the cytosol through a single opening of plasma membrane ion channels: SCCaFTs--fundamental calcium events. Cell Calcium. 2004 Jun;35(6):523-33. doi: 10.1016/j.ceca.2004.01.019. Review. PubMed PMID: 15110142.
De Crescenzo V, ZhuGe R, Velázquez-Marrero C, Lifshitz LM, Custer E, Carmichael J, Lai FA, Tuft RA, Fogarty KE, Lemos JR, Walsh JV Jr. Ca2+ syntillas, miniature Ca2+ release events in terminals of hypothalamic neurons, are increased in frequency by depolarization in the absence of Ca2+ influx. J Neurosci. 2004 Feb 4;24(5):1226-35. doi: 10.1523/JNEUROSCI.4286-03.2004. PubMed PMID: 14762141; PubMed Central PMCID: PMC6793580.
Lawe DC, Sitouah N, Hayes S, Chawla A, Virbasius JV, Tuft R, Fogarty K, Lifshitz L, Lambright D, Corvera S. Essential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization. Mol Biol Cell. 2003 Jul;14(7):2935-45. doi: 10.1091/mbc.e02-09-0591. Epub 2003 Mar 20. PubMed PMID: 12857876; PubMed Central PMCID: PMC165688.
Femino AM, Fogarty K, Lifshitz LM, Carrington W, Singer RH. Visualization of single molecules of mRNA in situ. Methods Enzymol. 2003;361:245-304. doi: 10.1016/s0076-6879(03)61015-3. PubMed PMID: 12624916.
Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ. Visualization of Ca2+ entry through single stretch-activated cation channels. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6404-9. doi: 10.1073/pnas.092654999. PubMed PMID: 11983921; PubMed Central PMCID: PMC122961.
Lawe DC, Chawla A, Merithew E, Dumas J, Carrington W, Fogarty K, Lifshitz L, Tuft R, Lambright D, Corvera S. Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1. J Biol Chem. 2002 Mar 8;277(10):8611-7. doi: 10.1074/jbc.M109239200. Epub 2001 Oct 15. PubMed PMID: 11602609.
Miyazaki K, Yano T, Schmidt DJ, Tokui T, Shibata M, Lifshitz LM, Kimura S, Tuft RA, Ikebe M. Rho-dependent agonist-induced spatio-temporal change in myosin phosphorylation in smooth muscle cells. J Biol Chem. 2002 Jan 4;277(1):725-34. doi: 10.1074/jbc.M108568200. Epub 2001 Oct 22. PubMed PMID: 11673466.
Stachelek SJ, Tuft RA, Lifschitz LM, Leonard DM, Farwell AP, Leonard JL. Real-time visualization of processive myosin 5a-mediated vesicle movement in living astrocytes. J Biol Chem. 2001 Sep 21;276(38):35652-9. doi: 10.1074/jbc.M103331200. Epub 2001 Aug 9. PubMed PMID: 11470781.
Kirber MT, Etter EF, Bellve KA, Lifshitz LM, Tuft RA, Fay FS, Walsh JV, Fogarty KE. Relationship of Ca2+ sparks to STOCs studied with 2D and 3D imaging in feline oesophageal smooth muscle cells. J Physiol. 2001 Mar 1;531(Pt 2):315-27. doi: 10.1111/j.1469-7793.2001.0315i.x. PubMed PMID: 11230506; PubMed Central PMCID: PMC2278474.
Patki V, Buxton J, Chawla A, Lifshitz L, Fogarty K, Carrington W, Tuft R, Corvera S. Insulin action on GLUT4 traffic visualized in single 3T3-l1 adipocytes by using ultra-fast microscopy. Mol Biol Cell. 2001 Jan;12(1):129-41. doi: 10.1091/mbc.12.1.129. PubMed PMID: 11160828; PubMed Central PMCID: PMC30573.
ZhuGe R, Fogarty KE, Tuft RA, Lifshitz LM, Sayar K, Walsh JV Jr. Dynamics of signaling between Ca(2+) sparks and Ca(2+)- activated K(+) channels studied with a novel image-based method for direct intracellular measurement of ryanodine receptor Ca(2+) current. J Gen Physiol. 2000 Dec;116(6):845-64. doi: 10.1085/jgp.116.6.845. PubMed PMID: 11099351; PubMed Central PMCID: PMC2231814.
Zou H, Lifshitz LM, Tuft RA, Fogarty KE, Singer JJ. Imaging Ca(2+) entering the cytoplasm through a single opening of a plasma membrane cation channel. J Gen Physiol. 1999 Oct;114(4):575-88. doi: 10.1085/jgp.114.4.575. PubMed PMID: 10498675; PubMed Central PMCID: PMC2229469.
Meininger GA, Moore ED, Schmidt DJ, Lifshitz LM, Fay FS. Distribution of active protein kinase C in smooth muscle. Biophys J. 1999 Aug;77(2):973-84. doi: 10.1016/S0006-3495(99)76948-1. PubMed PMID: 10423442; PubMed Central PMCID: PMC1300388.
Carrington W, Fogarty KE, Rizzuto R, Lifshitz LM, Tuft R. High Resolution 3-D Imaging of Living Cells by Image Restoration . In: Imaging Living Cells. Rizzuto R, Fasolato C, editors. Heidelberg: Springer; 1999. 30-50p.
Kiefer CR, McKenney JB, Trainor JF, Lambrecht RW, Bonkovsky HL, Lifshitz LM, Valeri CR, Snyder LM. Porphyrin loading of lipofuscin granules in inflamed striated muscle. Am J Pathol. 1998 Sep;153(3):703-8. doi: 10.1016/S0002-9440(10)65613-1. PubMed PMID: 9736020; PubMed Central PMCID: PMC1853029.
Unknown. Cover photo: image of dual labelled stem cell. Experimental Hematology, vol 26(7).; 1998 July. Cover photo produced by DAVE software. .
Rizzuto R, Pinton P, Carrington W, Fay FS, Fogarty KE, Lifshitz LM, Tuft RA, Pozzan T. Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science. 1998 Jun 12;280(5370):1763-6. doi: 10.1126/science.280.5370.1763. PubMed PMID: 9624056.
Femino AM, Fay FS, Fogarty KE, Singer RH. Visualization of Single RNA Transcripts in Situ. [Other]. Science vol. 280, pp. 585-590.; 1998 April. Cover photo (and others) produced by DAVE software.. .
Dictenberg J, Zimmerman W, Young A, Vidair C, Zheng Y, Carrington W, Fay F, Doxsey S. Pericentrin and Gamma-Tubulin Form a Protein Complex and are Organized into a Novel Lattice at the Centrosome. [Other]. Journal of Cell Biology, vol. 141(1), pp. 163-174.; 1998 April. Cover photo produced by DAVE software. .
Lifshitz LM. Determining data independence on a digitized membrane in three dimensions. IEEE Trans Med Imaging. 1998 Apr;17(2):299-303. doi: 10.1109/42.700742. PubMed PMID: 9688162.
Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS. Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J Neurosci. 1998 Jan 1;18(1):251-65. PubMed PMID: 9412505; PubMed Central PMCID: PMC6793411.
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