My Bibliography

select

Gaspers LD, Thomas AP, Hoek JB, Bartlett PJ. Ethanol Disrupts Hormone-Induced Calcium Signaling in Liver. Function (Oxf). 2021;2(2):zqab002. doi: 10.1093/function/zqab002. eCollection 2021. PubMed PMID: 33604575; PubMed Central PMCID: PMC7875097.

select

Gaspers LD, Pierobon N, Thomas AP. Intercellular calcium waves integrate hormonal control of glucose output in the intact liver. J Physiol. 2019 Jun;597(11):2867-2885. doi: 10.1113/JP277650. Epub 2019 Apr 29. PubMed PMID: 30968953; PubMed Central PMCID: PMC6647271.

select

Bartlett PJ, Antony AN, Agarwal A, Hilly M, Prince VL, Combettes L, Hoek JB, Gaspers LD. Chronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes. J Physiol. 2017 May 15;595(10):3143-3164. doi: 10.1113/JP273891. Epub 2017 Apr 18. PubMed PMID: 28220501; PubMed Central PMCID: PMC5430227.

select

Wang G, Mémin E, Murali I, Gaspers LD. The effect of chronic alcohol consumption on mitochondrial calcium handling in hepatocytes. Biochem J. 2016 Nov 1;473(21):3903-3921. doi: 10.1042/BCJ20160255. Epub 2016 Aug 31. PubMed PMID: 27582500; PubMed Central PMCID: PMC6469394.

select

Bartlett PJ, Metzger W, Gaspers LD, Thomas AP. Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations. J Biol Chem. 2015 Jul 24;290(30):18519-33. doi: 10.1074/jbc.M115.657767. Epub 2015 Jun 15. PubMed PMID: 26078455; PubMed Central PMCID: PMC4513112.

select

Gaspers LD, Bartlett PJ, Politi A, Burnett P, Metzger W, Johnston J, Joseph SK, Höfer T, Thomas AP. Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations. Cell Rep. 2014 Nov 20;9(4):1209-18. doi: 10.1016/j.celrep.2014.10.033. Epub 2014 Nov 13. PubMed PMID: 25456123; PubMed Central PMCID: PMC6469397.

select

Bartlett PJ, Gaspers LD, Pierobon N, Thomas AP. Calcium-dependent regulation of glucose homeostasis in the liver. Cell Calcium. 2014 Jun;55(6):306-16. doi: 10.1016/j.ceca.2014.02.007. Epub 2014 Feb 17. Review. PubMed PMID: 24630174; NIHMSID:NIHMS576896.

select

Fakira AK, Gaspers LD, Thomas AP, Li H, Jain MR, Elkabes S. Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice. Mol Cell Neurosci. 2012 Aug;51(1-2):22-31. doi: 10.1016/j.mcn.2012.07.001. Epub 2012 Jul 10. PubMed PMID: 22789621; PubMed Central PMCID: PMC3436994.

select

Gaspers LD, Mémin E, Thomas AP. Calcium-dependent physiologic and pathologic stimulus-metabolic response coupling in hepatocytes. Cell Calcium. 2012 Jul;52(1):93-102. doi: 10.1016/j.ceca.2012.04.009. Epub 2012 May 6. Review. PubMed PMID: 22564906; PubMed Central PMCID: PMC3391328.

select

Das S, Hajnóczky N, Antony AN, Csordás G, Gaspers LD, Clemens DL, Hoek JB, Hajnóczky G. Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats. Pflugers Arch. 2012 Jul;464(1):101-9. doi: 10.1007/s00424-012-1100-4. Epub 2012 Apr 19. PubMed PMID: 22526459; PubMed Central PMCID: PMC3799820.

select

Turner JD, Gaspers LD, Wang G, Thomas AP. Uncoupling protein-2 modulates myocardial excitation-contraction coupling. Circ Res. 2010 Mar 5;106(4):730-8. doi: 10.1161/CIRCRESAHA.109.206631. Epub 2010 Jan 7. PubMed PMID: 20056920; NIHMSID:NIHMS1014198.

select

Turner JD, Thomas AP, Reeves JP, Hantash BM. Calcineurin activation by slow calcium release from intracellular stores suppresses protein kinase C regulation of L-type calcium channels in L6 cells. Cell Calcium. 2009 Oct;46(4):242-7. doi: 10.1016/j.ceca.2009.07.006. Epub 2009 Sep 15. PubMed PMID: 19758695.

select

Lu X, Zheng R, Gonzalez J, Gaspers L, Kuzhikandathil E, Peluffo RD. L-lysine uptake in giant vesicles from cardiac ventricular sarcolemma: two components of cationic amino acid transport. Biosci Rep. 2009 Aug;29(4):271-81. doi: 10.1042/BSR20080159. PubMed PMID: 19032145.

select

Gaspers LD, Thomas AP. Calcium-dependent activation of mitochondrial metabolism in mammalian cells. Methods. 2008 Nov;46(3):224-32. doi: 10.1016/j.ymeth.2008.09.012. Epub 2008 Oct 12. PubMed PMID: 18854213; PubMed Central PMCID: PMC2640951.

select

Gulati P, Gaspers LD, Dann SG, Joaquin M, Nobukuni T, Natt F, Kozma SC, Thomas AP, Thomas G. Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metab. 2008 May;7(5):456-65. doi: 10.1016/j.cmet.2008.03.002. PubMed PMID: 18460336; PubMed Central PMCID: PMC2587347.

select

Kang L, Sanders NM, Dunn-Meynell AA, Gaspers LD, Routh VH, Thomas AP, Levin BE. Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons. Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R784-92. doi: 10.1152/ajpregu.00645.2007. Epub 2007 Dec 19. PubMed PMID: 18094065.

select

Pierobon N, Renard-Rooney DC, Gaspers LD, Thomas AP. Ryanodine receptors in liver. J Biol Chem. 2006 Nov 10;281(45):34086-95. doi: 10.1074/jbc.M607788200. Epub 2006 Sep 13. PubMed PMID: 16973607.

select

Politi A, Gaspers LD, Thomas AP, Höfer T. Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks. Biophys J. 2006 May 1;90(9):3120-33. doi: 10.1529/biophysj.105.072249. Epub 2006 Feb 24. PubMed PMID: 16500959; PubMed Central PMCID: PMC1432125.

select

Kang L, Dunn-Meynell AA, Routh VH, Gaspers LD, Nagata Y, Nishimura T, Eiki J, Zhang BB, Levin BE. Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing. Diabetes. 2006 Feb;55(2):412-20. doi: 10.2337/diabetes.55.02.06.db05-1229. PubMed PMID: 16443775.

select

Patel S, Gaspers LD, Pierobon N, Metzger W, Thomas AP. Measuring Single Cell and Subcellular Ca2+ Signals. In: Putney, Jr.,Jr.,James,W., editor. Calcium Signaling 2nd ed. Boca Raton, Florida: CRC Press, Inc.; 2005. p.387-416.

select

Gaspers LD, Thomas AP. Calcium signaling in liver. Cell Calcium. 2005 Sep-Oct;38(3-4):329-42. doi: 10.1016/j.ceca.2005.06.009. Review. PubMed PMID: 16139354.

select

Gaspers LD, Pierobon N, Thomas AP. Calcium Signaling. In: Dufour J, Clayien P, editors. Signaling Pathways in Liver Diseases Heidelberg, Germany: Springer-Verlag; 2004. Chapter 18; p.211-221.

select

Davidson MT, Deitch EA, Lu Q, Haskó G, Abungu B, Németh ZH, Zaets SB, Gaspers LD, Thomas AP, Xu DZ. Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms. Ann Surg. 2004 Jul;240(1):123-31. doi: 10.1097/01.sla.0000129341.94219.cf. PubMed PMID: 15213628; PubMed Central PMCID: PMC1356384.

select

Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE. Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes. 2004 Mar;53(3):549-59. doi: 10.2337/diabetes.53.3.549. PubMed PMID: 14988237.

select

Patel S, Gaspers LD, Boucherie S, Memin E, Stellato KA, Guillon G, Combettes L, Thomas AP. Inducible nitric-oxide synthase attenuates vasopressin-dependent Ca2+ signaling in rat hepatocytes. J Biol Chem. 2002 Sep 13;277(37):33776-82. doi: 10.1074/jbc.M201904200. Epub 2002 Jul 3. PubMed PMID: 12097323.

select

Dunn-Meynell AA, Routh VH, Kang L, Gaspers L, Levin BE. Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons. Diabetes. 2002 Jul;51(7):2056-65. doi: 10.2337/diabetes.51.7.2056. PubMed PMID: 12086933.

select

Irwin WA, Gaspers LD, Thomas JA. Inhibition of the mitochondrial permeability transition by aldehydes. Biochem Biophys Res Commun. 2002 Feb 22;291(2):215-9. doi: 10.1006/bbrc.2002.6457. PubMed PMID: 11846392.

select

Gaspers LD, Patel S, Morgan AP, Andersen PA, Thomas AP. Monitoring generation and propagation of calcium signals in multicellular preparations. In: Tepikin A, editor. Calcium Signalling: A Practical Approach 2nd ed. Oxford, UK: Oxford University Press; 2001. p.155-175.

select

Burnett P, Gaspers LD, Thomas AP. Control of Mitochondrial Metabolism by Calcium-Dependent Hormones. In: LeMasters JJ, Nieminen A, editors. Mitochondria in Pathogenesis New York, USA: Kluwer Academic/Plenum Publishers; 2001. p.153-175.

select

Smaili SS, Stellato KA, Burnett P, Thomas AP, Gaspers LD. Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2+ signals by enhancing Ca2+ uptake into the endoplasmic reticulum and mitochondria. J Biol Chem. 2001 Jun 29;276(26):23329-40. doi: 10.1074/jbc.M100989200. Epub 2001 Apr 25. PubMed PMID: 11323421.

select

Patel S, Robb-Gaspers LD, Thomas AP. Measuring Single Cell and Subcellular Ca2+ Signals. In: Putney, Jr.,James,W., editor. Calcium Signaling 1st ed. Boca Raton, Florida: CRC Press, Inc.; 2000. p.343-363.

select

Patel S, Robb-Gaspers LD, Stellato KA, Shon M, Thomas AP. Coordination of calcium signalling by endothelial-derived nitric oxide in the intact liver. Nat Cell Biol. 1999 Dec;1(8):467-71. doi: 10.1038/70249. PubMed PMID: 10587641.

select

Robb SJ, Gaspers LD, Wright KJ, Thomas AP, Connor JR. Influence of nitric oxide on cellular and mitochondrial integrity in oxidatively stressed astrocytes. J Neurosci Res. 1999 Apr 15;56(2):166-76. doi: 10.1002/(sici)1097-4547(19990415)56:2<166::aid-jnr6>3.0.co;2-s. PubMed PMID: 10494105.

select

Robb SJ, Robb-Gaspers LD, Scaduto RC Jr, Thomas AP, Connor JR. Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes. J Neurosci Res. 1999 Mar 15;55(6):674-86. doi: 10.1002/(SICI)1097-4547(19990315)55:6<674::AID-JNR3>3.0.CO;2-J. PubMed PMID: 10220109.

select

Rutter GA, Burnett P, Robb-Gaspers LD, Thomas AP, Denton RM, Griffiths EJ, Rizzuto R. Mitochondrial Ca2+ signalling. In: Verkhratsky A, Toescu EC, editors. Integrative aspects of calcium signalling. London, UK: Plenum Press; 1998. p.163-175. 399p.

select

Robb-Gaspers LD, Anderson PA, Thomas AP. Imaging whole organs. In: Rizzuto R, Fasolato C, editors. Imaging Living Cells New York, NY: Springer-Verlag Inc.; 1998. p.115-139.

select

Robb-Gaspers LD, Burnett P, Rutter GA, Denton RM, Rizzuto R, Thomas AP. Integrating cytosolic calcium signals into mitochondrial metabolic responses. EMBO J. 1998 Sep 1;17(17):4987-5000. doi: 10.1093/emboj/17.17.4987. PubMed PMID: 9724635; PubMed Central PMCID: PMC1170827.

select

Robb-Gaspers LD, Rutter GA, Burnett P, Hajnóczky G, Denton RM, Thomas AP. Coupling between cytosolic and mitochondrial calcium oscillations: role in the regulation of hepatic metabolism. Biochim Biophys Acta. 1998 Aug 10;1366(1-2):17-32. doi: 10.1016/s0005-2728(98)00118-2. PubMed PMID: 9714714.

select

Thomas AP, Robb-Gaspers LD. Subcellular and multicellular organization of calcium signaling in liver. Dynamic organization of the cell. In: Bailey GW, Corbett JM, Dimlich RV, Michael JR, Zaluzec NJ, editors. Microscopy and Microanalysis San Francisco, CA: San Francisco Press Inc.; 1996. p.736-737. 1060p.

select

Thomas AP, Bird GS, Hajnóczky G, Robb-Gaspers LD, Putney JW Jr. Spatial and temporal aspects of cellular calcium signaling. FASEB J. 1996 Nov;10(13):1505-17. Review. PubMed PMID: 8940296.

select

Thomas AP, Renard-Rooney DC, Hajnóczky G, Robb-Gaspers LD, Lin C, Rooney TA. Subcellular organization of calcium signalling in hepatocytes and the intact liver. Ciba Found Symp. 1995;188:18-35; discussion 35-49. doi: 10.1002/9780470514696.ch3. Review. PubMed PMID: 7587617.

select

Hajnóczky G, Robb-Gaspers LD, Seitz MB, Thomas AP. Decoding of cytosolic calcium oscillations in the mitochondria. Cell. 1995 Aug 11;82(3):415-24. doi: 10.1016/0092-8674(95)90430-1. PubMed PMID: 7634331.

select

Thomas AP, Robb-Gaspers LD, Rooney TA, Hajnóczky G, Renard-Rooney DC, Lin C. Spatial organization of oscillating calcium signals in liver. Biochem Soc Trans. 1995 Aug;23(3):642-8. doi: 10.1042/bst0230642. PubMed PMID: 8566434.

select

Robb-Gaspers LD, Thomas AP. Coordination of Ca2+ signaling by intercellular propagation of Ca2+ waves in the intact liver. J Biol Chem. 1995 Apr 7;270(14):8102-7. doi: 10.1074/jbc.270.14.8102. PubMed PMID: 7713913.

select

Thomas PJ, Gaspers LD, Pharr C, Thomas JA. Continuous measurement of mitochondrial pH gradients in isolated hepatocytes by difference ratio spectroscopy. Arch Biochem Biophys. 1991 Jul;288(1):250-60. doi: 10.1016/0003-9861(91)90192-l. PubMed PMID: 1898020.