My Bibliography

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Fesus L, Nagy L, Basilion JP, Davies PJ. Retinoic acid receptor transcripts in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1991 Aug 30;179(1):32-8. doi: 10.1016/0006-291x(91)91329-b. PubMed PMID: 1715692.

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Nagy L, Saydak M, Shipley N, Lu S, Basilion JP, Yan ZH, Syka P, Chandraratna RA, Stein JP, Heyman RA, Davies PJ. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J Biol Chem. 1996 Feb 23;271(8):4355-65. doi: 10.1074/jbc.271.8.4355. PubMed PMID: 8626785.

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Nagy L, Thomázy VA, Chandraratna RA, Heyman RA, Davies PJ. Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells. Leuk Res. 1996 Jun;20(6):499-505. doi: 10.1016/0145-2126(95)00118-2. PubMed PMID: 8709622.

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Yan ZH, Noonan S, Nagy L, Davies PJ, Stein JP. Retinoic acid induction of the tissue transglutaminase promoter is mediated by a novel response element. Mol Cell Endocrinol. 1996 Jul 1;120(2):203-12. doi: 10.1016/0303-7207(96)03826-9. PubMed PMID: 8832580.

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Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 1997 May 2;89(3):373-80. doi: 10.1016/s0092-8674(00)80218-4. PubMed PMID: 9150137.

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Balajthy Z, Kedei N, Nagy L, Davies PJ, Fésüs L. Lack of induction of tissue transglutaminase but activation of the preexisting enzyme in c-Myc-induced apoptosis of CHO cells. Biochem Biophys Res Commun. 1997 Jul 18;236(2):280-4. doi: 10.1006/bbrc.1997.6969. PubMed PMID: 9240425.

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Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 1997 Aug 8;90(3):569-80. doi: 10.1016/s0092-8674(00)80516-4. PubMed PMID: 9267036.

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Nagy L, Thomázy VA, Saydak MM, Stein JP, Davies PJ. The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Cell Death Differ. 1997 Oct;4(7):534-47. doi: 10.1038/sj.cdd.4400290. PubMed PMID: 14555966.

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Nagy L, Thomazy VA, Heyman RA, Davies PJ. Retinoid-induced apoptosis in normal and neoplastic tissues. Cell Death Differ. 1998 Jan;5(1):11-9. doi: 10.1038/sj.cdd.4400337. Review. PubMed PMID: 10200441.

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Nagy L, Thomázy VA, Davies PJ. A transgenic mouse model for the study of apoptosis during limb development. Cell Death Differ. 1998 Jan;5(1):126. doi: 10.1038/sj.cdd.4400318. PubMed PMID: 10200453.

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Lin RJ, Nagy L, Inoue S, Shao W, Miller WH Jr, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature. 1998 Feb 19;391(6669):811-4. doi: 10.1038/35895. PubMed PMID: 9486654.

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Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 1998 Apr 17;93(2):229-40. doi: 10.1016/s0092-8674(00)81574-3. PubMed PMID: 9568715.

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Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 1998 Apr 17;93(2):241-52. doi: 10.1016/s0092-8674(00)81575-5. PubMed PMID: 9568716.

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Dupé V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJ, Chambon P, Mark M. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 1;208(1):30-43. doi: 10.1006/dbio.1998.9176. PubMed PMID: 10075839.

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Tontonoz P, Nagy L. Regulation of macrophage gene expression by peroxisome-proliferator-activated receptor gamma: implications for cardiovascular disease. Curr Opin Lipidol. 1999 Dec;10(6):485-90. doi: 10.1097/00041433-199912000-00002. Review. PubMed PMID: 10680041.

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Nagy L, Kao HY, Love JD, Li C, Banayo E, Gooch JT, Krishna V, Chatterjee K, Evans RM, Schwabe JW. Mechanism of corepressor binding and release from nuclear hormone receptors. Genes Dev. 1999 Dec 15;13(24):3209-16. doi: 10.1101/gad.13.24.3209. PubMed PMID: 10617570; PubMed Central PMCID: PMC317208.

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Love JD, Gooch JT, Nagy L, Chatterjee VK, Schwabe JW. Transcriptional repression by nuclear receptors: mechanisms and role in disease. Biochem Soc Trans. 2000;28(4):390-6. Review. PubMed PMID: 10961926.

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Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L. Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circ Res. 2000 Sep 15;87(6):516-21. doi: 10.1161/01.res.87.6.516. PubMed PMID: 10988245.

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Szegezdi E, Szondy Z, Nagy L, Nemes Z, Friis RR, Davies PJ, Fésüs L. Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter. Cell Death Differ. 2000 Dec;7(12):1225-33. doi: 10.1038/sj.cdd.4400751. PubMed PMID: 11175260.

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Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med. 2001 Jan;7(1):48-52. doi: 10.1038/83336. PubMed PMID: 11135615.

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Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell. 2001 Jan;7(1):161-71. doi: 10.1016/s1097-2765(01)00164-2. PubMed PMID: 11172721.

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Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ. Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Mol Pharmacol. 2001 Apr;59(4):765-73. doi: 10.1124/mol.59.4.765. PubMed PMID: 11259621.

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Love JD, Gooch JT, Benko S, Li C, Nagy L, Chatterjee VK, Evans RM, Schwabe JW. The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. J Biol Chem. 2002 Mar 29;277(13):11385-91. doi: 10.1074/jbc.M110869200. Epub 2002 Jan 8. PubMed PMID: 11782480.

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Benko S, Love JD, Beládi M, Schwabe JW, Nagy L. Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor. J Biol Chem. 2003 Oct 31;278(44):43797-806. doi: 10.1074/jbc.M306199200. Epub 2003 Aug 12. PubMed PMID: 12917445.

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Nagy L, Schwabe JW. Mechanism of the nuclear receptor molecular switch. Trends Biochem Sci. 2004 Jun;29(6):317-24. doi: 10.1016/j.tibs.2004.04.006. Review. PubMed PMID: 15276186.

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Szatmari I, Gogolak P, Im JS, Dezso B, Rajnavolgyi E, Nagy L. Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity. 2004 Jul;21(1):95-106. doi: 10.1016/j.immuni.2004.06.003. PubMed PMID: 15345223.

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Szanto A, Benko S, Szatmari I, Balint BL, Furtos I, Rühl R, Molnar S, Csiba L, Garuti R, Calandra S, Larsson H, Diczfalusy U, Nagy L. Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages. Mol Cell Biol. 2004 Sep;24(18):8154-66. doi: 10.1128/MCB.24.18.8154-8166.2004. PubMed PMID: 15340076; PubMed Central PMCID: PMC515045.

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Balint BL, Gabor P, Nagy L. Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line. Immunobiology. 2005;210(2-4):141-52. doi: 10.1016/j.imbio.2005.05.009. PubMed PMID: 16164021.

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Szanto A, Nagy L. Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells. Mol Pharmacol. 2005 Jun;67(6):1935-43. doi: 10.1124/mol.104.006445. Epub 2005 Mar 1. PubMed PMID: 15741503.

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Balint BL, Szanto A, Madi A, Bauer UM, Gabor P, Benko S, Puskás LG, Davies PJ, Nagy L. Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Mol Cell Biol. 2005 Jul;25(13):5648-63. doi: 10.1128/MCB.25.13.5648-5663.2005. PubMed PMID: 15964820; PubMed Central PMCID: PMC1156990.

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Kappelmayer J, Simon A, Katona E, Szanto A, Nagy L, Kiss A, Kiss C, Muszbek L. Coagulation factor XIII-A. A flow cytometric intracellular marker in the classification of acute myeloid leukemias. Thromb Haemost. 2005 Aug;94(2):454-9. doi: 10.1160/TH05-03-0206. PubMed PMID: 16113839.

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Djazayeri K, Szilvássy Z, Peitl B, Németh J, Nagy L, Kiss A, Szabó B, Benko I. Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment. Eur J Pharmacol. 2005 Oct 17;522(1-3):122-9. doi: 10.1016/j.ejphar.2005.08.053. Epub 2005 Oct 6. PubMed PMID: 16213483.

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Nagy L, Szanto A. Roles for lipid-activated transcription factors in atherosclerosis. Mol Nutr Food Res. 2005 Nov;49(11):1072-4. doi: 10.1002/mnfr.200500097. Review. PubMed PMID: 16208627.

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Réthi B, Gogolák P, Szatmari I, Veres A, Erdôs E, Nagy L, Rajnavölgyi E, Terhorst C, Lányi A. SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells. Blood. 2006 Apr 1;107(7):2821-9. doi: 10.1182/blood-2005-06-2265. Epub 2005 Nov 29. PubMed PMID: 16317102; PubMed Central PMCID: PMC1895370.

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Nagy L, Schüle R, Gronemeyer H. Twenty years of nuclear receptors: Conference on Nuclear Receptors: from Chromatin to Disease. EMBO Rep. 2006 Jun;7(6):579-84. doi: 10.1038/sj.embor.7400711. Epub 2006 May 26. Review. PubMed PMID: 16729019; PubMed Central PMCID: PMC1479599.

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Szatmari I, Vámosi G, Brazda P, Balint BL, Benko S, Széles L, Jeney V, Ozvegy-Laczka C, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. J Biol Chem. 2006 Aug 18;281(33):23812-23. doi: 10.1074/jbc.M604890200. Epub 2006 Jun 19. PubMed PMID: 16785230.

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Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, Marais D, Schwabe J, Barroso I, Trembath R, Wareham N, Nagy L, Gurnell M, O'Rahilly S, Chatterjee K. Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance. Cell Metab. 2006 Oct;4(4):303-11. doi: 10.1016/j.cmet.2006.09.003. PubMed PMID: 17011503; PubMed Central PMCID: PMC1821092.

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Székvölgyi L, Bálint BL, Imre L, Goda K, Szabó M, Nagy L, Szabó G. Chip-on-beads: flow-cytometric evaluation of chromatin immunoprecipitation. Cytometry A. 2006 Oct 1;69(10):1086-91. doi: 10.1002/cyto.a.20325. PubMed PMID: 16998871.

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Szatmari I, Pap A, Rühl R, Ma JX, Illarionov PA, Besra GS, Rajnavolgyi E, Dezso B, Nagy L. PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. J Exp Med. 2006 Oct 2;203(10):2351-62. doi: 10.1084/jem.20060141. Epub 2006 Sep 18. PubMed PMID: 16982809; PubMed Central PMCID: PMC2118109.

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Szatmari I, Rajnavolgyi E, Nagy L. PPARgamma, a lipid-activated transcription factor as a regulator of dendritic cell function. Ann N Y Acad Sci. 2006 Nov;1088:207-18. doi: 10.1196/annals.1366.013. Review. PubMed PMID: 17192567.

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Gogolak P, Rethi B, Szatmari I, Lanyi A, Dezso B, Nagy L, Rajnavolgyi E. Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma. Blood. 2007 Jan 15;109(2):643-52. doi: 10.1182/blood-2006-04-016840. Epub 2006 Sep 12. PubMed PMID: 16968896.

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Széles L, Töröcsik D, Nagy L. PPARgamma in immunity and inflammation: cell types and diseases. Biochim Biophys Acta. 2007 Aug;1771(8):1014-30. doi: 10.1016/j.bbalip.2007.02.005. Epub 2007 Feb 24. Review. PubMed PMID: 17418635.

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Székvölgyi L, Rákosy Z, Bálint BL, Kókai E, Imre L, Vereb G, Bacsó Z, Goda K, Varga S, Balázs M, Dombrádi V, Nagy L, Szabó G. Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14964-9. doi: 10.1073/pnas.0702269104. Epub 2007 Sep 11. PubMed PMID: 17848525; PubMed Central PMCID: PMC1986596.

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Szatmari I, Töröcsik D, Agostini M, Nagy T, Gurnell M, Barta E, Chatterjee K, Nagy L. PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism. Blood. 2007 Nov 1;110(9):3271-80. doi: 10.1182/blood-2007-06-096222. Epub 2007 Jul 30. PubMed PMID: 17664351.

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Csanky E, Olivova P, Rajnavolgyi E, Hempel W, Tardieu N, Katalin ET, Jullien A, Malderez-Bloes C, Kuras M, Duval MX, Nagy L, Scholtz B, Hancock W, Karger B, Guttman A, Takacs L. Monoclonal antibody proteomics: discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step. Electrophoresis. 2007 Dec;28(23):4401-6. doi: 10.1002/elps.200700256. PubMed PMID: 18041035.

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Itoh T, Fairall L, Amin K, Inaba Y, Szanto A, Balint BL, Nagy L, Yamamoto K, Schwabe JW. Structural basis for the activation of PPARgamma by oxidized fatty acids. Nat Struct Mol Biol. 2008 Sep;15(9):924-31. doi: 10.1038/nsmb.1474. PubMed PMID: 19172745; PubMed Central PMCID: PMC2939985.

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Szanto A, Nagy L. The many faces of PPARgamma: anti-inflammatory by any means?. Immunobiology. 2008;213(9-10):789-803. doi: 10.1016/j.imbio.2008.07.015. Epub 2008 Sep 2. Review. PubMed PMID: 18926294.

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Szatmari I, Nagy L. Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function. EMBO J. 2008 Sep 17;27(18):2353-62. doi: 10.1038/emboj.2008.160. Epub 2008 Aug 21. Review. PubMed PMID: 18716631; PubMed Central PMCID: PMC2525841.

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Dobrosi N, Tóth BI, Nagy G, Dózsa A, Géczy T, Nagy L, Zouboulis CC, Paus R, Kovács L, Bíró T. Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. FASEB J. 2008 Oct;22(10):3685-95. doi: 10.1096/fj.07-104877. Epub 2008 Jul 2. PubMed PMID: 18596221.

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Seres L, Cserepes J, Elkind NB, Törocsik D, Nagy L, Sarkadi B, Homolya L. Functional ABCG1 expression induces apoptosis in macrophages and other cell types. Biochim Biophys Acta. 2008 Oct;1778(10):2378-87. doi: 10.1016/j.bbamem.2008.06.010. Epub 2008 Jun 19. PubMed PMID: 18619413.