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Ikonomou L, Bastin G, Schneider YJ, Agathos SN. Growth on microcarriers and nutritional needs of high density insect cell cultures . In: Animal cell technology: Products from cells, cells as products. Bernard A, Griffiths B, Noé W, Wurm F, editors. Dordrecht: Kluwer Academic Publishers; 1999. p.371-373.
Ikonomou L, Drugmand JC, Bastin G, Schneider YJ, Agathos SN. Physiology of insect cells cultured in a new serum-free medium . In: Animal Cell Technology: From Target to Market. Lindner-Olsson E, Chatzissavidou N, Lüllau E, editors. Dordrecht: Kluwer Academic Publishers; 2001. p.338-340.
Drugmand JC, Ikonomou L, Schneider YJ, Agathos SN. Growth of High-Five cells on Cultispher-S microcarriers . In: Animal Cell Technology: From Target to Market. Lindner-Olsson E, Chatzissavidou N, Lüllau E, editors. Dordrecht: Kluwer Academic Publishers; 2001. p.332-334.
Ikonomou L, Bastin G, Schneider YJ, Agathos SN. Design of an efficient medium for insect cell growth and recombinant protein production. In Vitro Cell Dev Biol Anim. 2001 Oct;37(9):549-59. doi: 10.1290/1071-2690(2001)037<0549:doaemf>2.0.co;2. PubMed PMID: 11710429.
Ikonomou L, Peeters-Joris C, Schneider YJ, Agathos SN. Supernatant proteolytic activities of High-Five insect cells grown in serum-free culture. Biotechnology Letters. 2002; 24(12):965-969.
Ikonomou L, Drugmand JC, Bastin G, Schneider YJ, Agathos SN. Microcarrier culture of lepidopteran cell lines: implications for growth and recombinant protein production. Biotechnol Prog. 2002 Nov-Dec;18(6):1345-55. doi: 10.1021/bp0255107. PubMed PMID: 12467471.
Ikonomou L, Schneider YJ, Agathos SN. Insect cell culture for industrial production of recombinant proteins. Appl Microbiol Biotechnol. 2003 Jul;62(1):1-20. doi: 10.1007/s00253-003-1223-9. Epub 2003 May 6. Review. PubMed PMID: 12733003.
Ikonomou L, Bastin G, Schneider YJ, Agathos SN. Effect of Partial Medium Replacement on Cell Growth and Protein Production for the High-Fivetrade mark insect cell line. Cytotechnology. 2004 Jan;44(1-2):67-76. doi: 10.1023/B:CYTO.0000043413.53044.fa. PubMed PMID: 19003230; PubMed Central PMCID: PMC3449497.
Davani B, Ikonomou L, Raaka BM, Geras-Raaka E, Morton RA, Marcus-Samuels B, Gershengorn MC. Human islet-derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone-expressing cells in vivo. Stem Cells. 2007 Dec;25(12):3215-22. doi: 10.1634/stemcells.2007-0323. Epub 2007 Sep 27. PubMed PMID: 17901402.
Ikonomou L, Geras-Raaka E, Raaka BM, Gershengorn MC. Beta-catenin signalling in mesenchymal islet-derived precursor cells. Cell Prolif. 2008 Jun;41(3):474-91. doi: 10.1111/j.1365-2184.2008.00527.x. Epub 2008 Apr 14. PubMed PMID: 18422699; PubMed Central PMCID: PMC2677447.
Lenas P, Moreno A, Ikonomou L, Mayer J, Honda H, Novellino A, Pizarro C, Nicodemou-Lena E, Rodergas S, Pintor J. The complementarity of the technical tools of tissue engineering and the concepts of artificial organs for the design of functional bioartificial tissues. Artif Organs. 2008 Sep;32(9):742-7. doi: 10.1111/j.1525-1594.2008.00599.x. Epub 2008 Jul 30. PubMed PMID: 18684202.
Davani B, Ariely S, Ikonomou L, Oron Y, Gershengorn MC. Human islet-derived precursor cells can cycle between epithelial clusters and mesenchymal phenotypes. J Cell Mol Med. 2009 Aug;13(8B):2570-81. doi: 10.1111/j.1582-4934.2008.00570.x. Epub 2008 Nov 3. PubMed PMID: 19175683; PubMed Central PMCID: PMC2819554.
Lenas P, Saravia V, Toca-Herrera JL, Paternain JL, Ikonomou L, Mayer J, Probst I, Crawford J, Vassilicos JC, Moreno A, Dravaliari A, Kolodkin A, Guzmán-Aránguez A, Pintor J. Functional biomimetics in tissue engineering: engineering emergent tissue functions in vitro through complexity and networks science . In: Biomimetics in Biophysics: Model systems, experimental techniques and computation. Toca-Herrera JL, editor. Kerala, India: Research Signpost; 2010. Chapter 9; p.155-192.
Lenas P, Luyten FP, Saravia V, Toca-Herrera JL, Ikonomou L, Nicodemou-Lena E, Rodergas S, Ito A, Honda H, Dinnyes A, Mayer J, Arzimanoglou I, Martin Gordillo F, Maccione A. Process biomimetics in tissue engineering: engineering the in vitro tissue development through systems biology and networks science . In: Biomimetics in Biophysics: Model systems, experimental techniques and computation. Toca-Herrera JL, editor. Kerala, India: Research Signpost; 2010. Chapter 10; p.193-225.
Ott HC, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, Kotton D, Vacanti JP. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med. 2010 Aug;16(8):927-33. doi: 10.1038/nm.2193. Epub 2010 Jul 13. PubMed PMID: 20628374.
Kotova S, Vijayasarathy C, Dimitriadis EK, Ikonomou L, Jaffe H, Sieving PA. Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study. Biochemistry. 2010 Aug 24;49(33):7023-32. doi: 10.1021/bi1007029. PubMed PMID: 20677810; PubMed Central PMCID: PMC2929131.
Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED. Programmatic change: lung disease research in the era of induced pluripotency. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L830-5. doi: 10.1152/ajplung.00255.2011. Epub 2011 Oct 7. PubMed PMID: 21984571; PubMed Central PMCID: PMC3233828.
Diaz PI, Xie Z, Sobue T, Thompson A, Biyikoglu B, Ricker A, Ikonomou L, Dongari-Bagtzoglou A. Synergistic interaction between Candida albicans and commensal oral streptococci in a novel in vitro mucosal model. Infect Immun. 2012 Feb;80(2):620-32. doi: 10.1128/IAI.05896-11. Epub 2011 Nov 21. PubMed PMID: 22104105; PubMed Central PMCID: PMC3264323.
Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean JC, Kwok LW, Mou H, Rajagopal J, Shen SS, Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI, Kotton DN. Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012 Apr 6;10(4):398-411. doi: 10.1016/j.stem.2012.01.019. PubMed PMID: 22482505; PubMed Central PMCID: PMC3322392.
Longmire TA, Ikonomou L, Kotton DN. Mouse ESC Differentiation to Nkx2.1+ Lung and Thyroid Progenitors. Bio Protoc. 2012 Nov 20;2(22). doi: 10.21769/bioprotoc.295. PubMed PMID: 27453901; PubMed Central PMCID: PMC4957957.
Ikonomou L, Kotton DN. Derivation of Endodermal Progenitors From Pluripotent Stem Cells. J Cell Physiol. 2015 Feb;230(2):246-58. doi: 10.1002/jcp.24771. Review. PubMed PMID: 25160562; PubMed Central PMCID: PMC4344429.
Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 2015 Nov 5;17(5):527-42. doi: 10.1016/j.stem.2015.09.004. Epub 2015 Oct 22. PubMed PMID: 26593959; PubMed Central PMCID: PMC4666682.
Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ. The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act. Ann Am Thorac Soc. 2016 Aug;13(8):1205-7. doi: 10.1513/AnnalsATS.201604-277ED. PubMed PMID: 27509147.
Wilson A, Ikonomou L. Development and Bioengineering of Lung Regeneration . In: Organ Regeneration Based on Developmental Biology. Tsuji T, editor. Singapore: Springer Singapore; 2017. Chapter 13; p.237-257.
Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kańduła MM, Monti S, Hollenberg AN, Mehta P, Kotton DN, Ikonomou L. Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1. Stem Cell Reports. 2017 Feb 14;8(2):216-225. doi: 10.1016/j.stemcr.2016.12.024. Epub 2017 Feb 2. PubMed PMID: 28162994; PubMed Central PMCID: PMC5312259.
Ikonomou L, Panoskaltsis-Mortari A, Wagner DE, Freishtat RJ, Weiss DJ. Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem. Am J Respir Crit Care Med. 2017 Apr 1;195(7):P13-P14. doi: 10.1164/rccm.1957P13. PubMed PMID: 28362195.
Hartman CD, Isenberg BC, Chua SG, Wong JY. Extracellular matrix type modulates cell migration on mechanical gradients. Exp Cell Res. 2017 Oct 15;359(2):361-366. doi: 10.1016/j.yexcr.2017.08.018. Epub 2017 Aug 15. PubMed PMID: 28821395; PubMed Central PMCID: PMC5603420.
Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN. Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development. 2017 Nov 1;144(21):3879-3893. doi: 10.1242/dev.150193. Epub 2017 Sep 25. PubMed PMID: 28947536; PubMed Central PMCID: PMC5702071.
Weiss DJ, Turner L, Levine AD, Ikonomou L. Medical societies, patient education initiatives, public debate and marketing of unproven stem cell interventions. Cytotherapy. 2018 Feb;20(2):165-168. doi: 10.1016/j.jcyt.2017.10.002. Epub 2017 Nov 24. PubMed PMID: 29239793.
Lenas P, Ikonomou L. Developmental engineering: design of clinically efficacious bioartificial tissues through developmental and systems biology. Sci China Life Sci. 2018 Aug;61(8):978-981. doi: 10.1007/s11427-017-9255-3. Epub 2018 Jun 25. PubMed PMID: 29951951; PubMed Central PMCID: PMC6192244.
Wagner DE, Turner L, Panoskaltsis-Mortari A, Weiss DJ, Ikonomou L. Co-opting of ClinicalTrials.gov by patient-funded studies. Lancet Respir Med. 2018 Aug;6(8):579-581. doi: 10.1016/S2213-2600(18)30242-X. Epub 2018 Jun 19. PubMed PMID: 29934051.
Cuende N, Rasko JEJ, Koh MBC, Dominici M, Ikonomou L. Cell, tissue and gene products with marketing authorization in 2018 worldwide. Cytotherapy. 2018 Nov;20(11):1401-1413. doi: 10.1016/j.jcyt.2018.09.010. Epub 2018 Oct 24. PubMed PMID: 30366616.
Jamal M, Lewandowski SL, Lawton ML, Huang GT, Ikonomou L. Derivation and characterization of putative craniofacial mesenchymal progenitor cells from human induced pluripotent stem cells. Stem Cell Res. 2018 Dec;33:100-109. doi: 10.1016/j.scr.2018.10.015. Epub 2018 Oct 10. PubMed PMID: 30340089; PubMed Central PMCID: PMC6294687.
Ikonomou L, Wagner DE, Turner L, Weiss DJ. Translating Basic Research into Safe and Effective Cell-based Treatments for Respiratory Diseases. Ann Am Thorac Soc. 2019 Jun;16(6):657-668. doi: 10.1513/AnnalsATS.201812-890CME. Review. PubMed PMID: 30917290.
Ryan AL, Ikonomou L, Atarod S, Bölükbas DA, Collins J, Freishtat R, Hawkins F, Gilpin SE, Uhl FE, Uriarte JJ, Weiss DJ, Wagner DE. Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017. An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2019 Oct;61(4):429-439. doi: 10.1165/rcmb.2019-0286ST. PubMed PMID: 31573338; PubMed Central PMCID: PMC6775946.
Ikonomou L, Herriges MJ, Lewandowski SL, Marsland R 3rd, Villacorta-Martin C, Caballero IS, Frank DB, Sanghrajka RM, Dame K, Kańduła MM, Hicks-Berthet J, Lawton ML, Christodoulou C, Fabian AJ, Kolaczyk E, Varelas X, Morrisey EE, Shannon JM, Mehta P, Kotton DN. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020 Jan 31;11(1):635. doi: 10.1038/s41467-020-14348-3. PubMed PMID: 32005814; PubMed Central PMCID: PMC6994558.
Ikonomou L, Weiss DJ. Turning the Tide on Unproven Cell-Based Interventions. Chest. 2020 Apr;157(4):774-775. doi: 10.1016/j.chest.2019.10.035. PubMed PMID: 32252930.
Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors. bioRxiv. 2020 Jun 4;. doi: 10.1101/2020.06.03.132639. PubMed PMID: 32577635; PubMed Central PMCID: PMC7302183.
Ikonomou L, Wagner DE, Gilpin SE, Weiss DJ, Ryan AL. Technological advances in study of lung regenerative medicine:perspective from the 2019 Vermont lung stem cell conference. Cytotherapy. 2020 Oct;22(10):519-520. doi: 10.1016/j.jcyt.2020.04.001. Epub 2020 Jun 2. PubMed PMID: 32507605.
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