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Serrano J, Kondo S, Link GM, Brown IS, Pratley RE, Baskin KK, Goodpaster BH, Coen PM, Kyriazis GA. A partial loss-of-function variant (Ile191Val) of the TAS1R2 glucose receptor is associated with enhanced responses to exercise training in older adults with obesity: A translational study. Metabolism. 2025 Jan;162:156045. doi: 10.1016/j.metabol.2024.156045. Epub 2024 Oct 10. PubMed PMID: 39393515; PubMed Central PMCID: PMC11637915.
Kolonay DW, Sattler KM, Strawser C, Rafael-Fortney J, Mihaylova MM, Miller KE, Lepper C, Baskin KK. Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. Front Cell Dev Biol. 2024;12:1331563. doi: 10.3389/fcell.2024.1331563. eCollection 2024. PubMed PMID: 38690566; PubMed Central PMCID: PMC11058648.
Rabolli CP, Naarmann-de Vries IS, Makarewich CA, Baskin KK, Dieterich C, Accornero F. Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism. Circulation. 2024 Apr 16;149(16):1319-1322. doi: 10.1161/CIRCULATIONAHA.123.066473. Epub 2024 Apr 15. PubMed PMID: 38620081.
Mahler CA, Snoke DB, Cole RM, Angelotti A, Sparagna GC, Baskin KK, Ni A, Belury MA. Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration. J Nutr. 2024 Mar;154(3):856-865. doi: 10.1016/j.tjnut.2023.12.037. Epub 2023 Dec 30. PubMed PMID: 38160803.
Rao A, Lyu B, Jahan I, Lubertozzi A, Zhou G, Tedeschi F, Jankowsky E, Kang J, Carstens B, Poss KD, Baskin K, Goldman JA. The translation initiation factor homolog eif4e1c regulates cardiomyocyte metabolism and proliferation during heart regeneration. Development. 2023 Oct 15;150(20). doi: 10.1242/dev.201376. Epub 2023 Jun 12. PubMed PMID: 37306388; PubMed Central PMCID: PMC10281269.
Butler MJ, Mackey-Alfonso SE, Massa N, Baskin KK, Barrientos RM. Dietary fatty acids differentially impact phagocytosis, inflammatory gene expression, and mitochondrial respiration in microglial and neuronal cell models. Front Cell Neurosci. 2023;17:1227241. doi: 10.3389/fncel.2023.1227241. eCollection 2023. PubMed PMID: 37636589; PubMed Central PMCID: PMC10448530.
Shu Y, Gumma N, Hassan F, Branch DA, Baer LA, Ostrowski MC, Stanford KI, Baskin KK, Mehta KD. Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity. J Biol Chem. 2023 Aug;299(8):104917. doi: 10.1016/j.jbc.2023.104917. Epub 2023 Jun 12. PubMed PMID: 37315788; PubMed Central PMCID: PMC10393818.
Moellering DR, Smith-Johnston K, Kelley C, Sammy MJ, Benedict J, Brock G, Johnson J, Baskin KK, Jarjour WN, Belury MA, Reiser PJ, Nagareddy PR, Hanaoka BY. Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. Arthritis Res Ther. 2023 May 20;25(1):85. doi: 10.1186/s13075-023-03065-z. PubMed PMID: 37210569; PubMed Central PMCID: PMC10199606.
Snoke DB, Mahler CA, Angelotti A, Cole RM, Sparagna GC, Baskin KK, Belury MA. Linoleic Acid-Enriched Diet Increases Mitochondrial Tetralinoleoyl Cardiolipin, OXPHOS Protein Levels, and Uncoupling in Interscapular Brown Adipose Tissue during Diet-Induced Weight Gain. Biology (Basel). 2022 Dec 21;12(1). doi: 10.3390/biology12010009. PubMed PMID: 36671702; PubMed Central PMCID: PMC9854875.
Song K, Wang Z, Baskin KK. Editorial: Metabolic regulation in cardiovascular homeostasis and disease. Front Cardiovasc Med. 2022;9:995207. doi: 10.3389/fcvm.2022.995207. eCollection 2022. PubMed PMID: 35990953; PubMed Central PMCID: PMC9382290.
Vidal P, Baer LA, Félix-Soriano E, Yang FT, Branch DA, Baskin KK, Stanford KI. Distinct Effects of High-Fat and High-Phosphate Diet on Glucose Metabolism and the Response to Voluntary Exercise in Male Mice. Nutrients. 2022 Mar 12;14(6). doi: 10.3390/nu14061201. PubMed PMID: 35334860; PubMed Central PMCID: PMC8951123.
Longenecker JZ, Petrosino JM, Martens CR, Hinger SA, Royer CJ, Dorn LE, Branch DA, Serrano J, Stanford KI, Kyriazis GA, Baskin KK, Accornero F. Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function. Mol Metab. 2021 Dec;54:101343. doi: 10.1016/j.molmet.2021.101343. Epub 2021 Sep 25. PubMed PMID: 34583010; PubMed Central PMCID: PMC8529557.
Shu Y, Hassan F, Coppola V, Baskin KK, Han X, Mehta NK, Ostrowski MC, Mehta KD. Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis. Mol Metab. 2021 Feb;44:101133. doi: 10.1016/j.molmet.2020.101133. Epub 2020 Nov 30. PubMed PMID: 33271332; PubMed Central PMCID: PMC7785956.
Pinckard K, Baskin KK, Stanford KI. Effects of Exercise to Improve Cardiovascular Health. Front Cardiovasc Med. 2019;6:69. doi: 10.3389/fcvm.2019.00069. eCollection 2019. Review. PubMed PMID: 31214598; PubMed Central PMCID: PMC6557987.
Peri-Okonny P, Baskin KK, Iwamoto G, Mitchell JH, Smith SA, Kim HK, Szweda LI, Bassel-Duby R, Fujikawa T, Castorena CM, Richardson J, Shelton JM, Ayers C, Berry JD, Malladi VS, Hu MC, Moe OW, Scherer PE, Vongpatanasin W. High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice. Circulation. 2019 Mar 12;139(11):1422-1434. doi: 10.1161/CIRCULATIONAHA.118.037550. PubMed PMID: 30612451; PubMed Central PMCID: PMC6411426.
Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN. MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation. Cell Rep. 2018 Jun 26;23(13):3701-3709. doi: 10.1016/j.celrep.2018.05.058. PubMed PMID: 29949755; PubMed Central PMCID: PMC6066340.
Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN. MED12 regulates a transcriptional network of calcium-handling genes in the heart. JCI Insight. 2017 Jul 20;2(14). doi: 10.1172/jci.insight.91920. eCollection 2017 Jul 20. PubMed PMID: 28724790; PubMed Central PMCID: PMC5518564.
Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN. CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice. Sci Adv. 2017 Apr;3(4):e1602814. doi: 10.1126/sciadv.1602814. eCollection 2017 Apr. PubMed PMID: 28439558; PubMed Central PMCID: PMC5389745.
Amoasii L, Holland W, Sanchez-Ortiz E, Baskin KK, Pearson M, Burgess SC, Nelson BR, Bassel-Duby R, Olson EN. A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism. Genes Dev. 2016 Feb 15;30(4):434-46. doi: 10.1101/gad.273128.115. PubMed PMID: 26883362; PubMed Central PMCID: PMC4762428.
Baskin KK, Winders BR, Olson EN. Muscle as a "mediator" of systemic metabolism. Cell Metab. 2015 Feb 3;21(2):237-248. doi: 10.1016/j.cmet.2014.12.021. Review. PubMed PMID: 25651178; PubMed Central PMCID: PMC4398026.
Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN. MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver. EMBO Mol Med. 2014 Dec;6(12):1610-21. doi: 10.15252/emmm.201404218. PubMed PMID: 25422356; PubMed Central PMCID: PMC4287978.
Baskin KK, Rodriguez MR, Kansara S, Chen W, Carranza S, Frazier OH, Glass DJ, Taegtmeyer H. MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart. J Mol Cell Cardiol. 2014 Jul;72:168-76. doi: 10.1016/j.yjmcc.2014.03.006. Epub 2014 Mar 18. PubMed PMID: 24650875; PubMed Central PMCID: PMC4037330.
Kwartler CS, Chen J, Thakur D, Li S, Baskin K, Wang S, Wang ZV, Walker L, Hill JA, Epstein HF, Taegtmeyer H, Milewicz DM. Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in vascular smooth muscle cells. J Biol Chem. 2014 May 16;289(20):14075-88. doi: 10.1074/jbc.M113.499277. Epub 2014 Apr 7. PubMed PMID: 24711452; PubMed Central PMCID: PMC4022877.
Baskin KK, Bookout AL, Olson EN. The heart-liver metabolic axis: defective communication exacerbates disease. EMBO Mol Med. 2014 Apr;6(4):436-8. doi: 10.1002/emmm.201303800. Epub 2014 Mar 12. PubMed PMID: 24623378; PubMed Central PMCID: PMC3992070.
Baskin KK, Taegtmeyer H. AMP-activated protein kinase regulates E3 ligases in rodent heart. Circ Res. 2011 Oct 28;109(10):1153-61. doi: 10.1161/CIRCRESAHA.111.252742. Epub 2011 Sep 15. PubMed PMID: 21921267; PubMed Central PMCID: PMC3254015.
Baskin KK, Taegtmeyer H. An expanded role for AMP-activated protein kinase: regulator of myocardial protein degradation. Trends Cardiovasc Med. 2011 May;21(4):124-7. doi: 10.1016/j.tcm.2012.03.010. Review. PubMed PMID: 22681968; PubMed Central PMCID: PMC3372865.
Baskin KK, Taegtmeyer H. Taking pressure off the heart: the ins and outs of atrophic remodelling. Cardiovasc Res. 2011 May 1;90(2):243-50. doi: 10.1093/cvr/cvr060. Epub 2011 Feb 25. Review. PubMed PMID: 21354996; PubMed Central PMCID: PMC3115281.
Razeghi P, Baskin KK, Sharma S, Young ME, Stepkowski S, Essop MF, Taegtmeyer H. Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart. Biochem Biophys Res Commun. 2006 Apr 7;342(2):361-4. doi: 10.1016/j.bbrc.2006.01.163. Epub 2006 Feb 8. PubMed PMID: 16483544.
Parker-Thornburg JV, Alana JL, Smith CN, Detry M, Rojas ML, Baskin KK. Cryopreserved morulae can be used to efficiently generate germline-transmitting chimeras by blastocyst injection. Transgenic Res. 2005 Oct;14(5):685-90. doi: 10.1007/s11248-005-7022-6. PubMed PMID: 16245159.
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