Genes for 5'mRNA cap binding proteins, eif4ea and eif4eb, have alternative roles during heart regeneration.
Dev Biol.
2026 Jun;534:50-60. doi: 10.1016/j.ydbio.2026.02.014. Epub 2026 Mar 7. PubMed PMID:
41802658.
Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats.
bioRxiv.
2026 Feb 2;. doi: 10.64898/2026.01.30.702943. PubMed PMID:
41676478; PubMed Central PMCID:
PMC12889468.
The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis.
Brain Behav Immun.
2026 Feb;132:106220. doi: 10.1016/j.bbi.2025.106220. Epub 2025 Dec 9. PubMed PMID:
41381013; PubMed Central PMCID:
PMC12990974.
Med13 and Med13L: Critical redundant players in basal cardiac function and gene expression.
J Mol Cell Cardiol Plus.
2025 Sep;13:100481. doi: 10.1016/j.jmccpl.2025.100481. eCollection 2025 Sep. PubMed PMID:
40989238; PubMed Central PMCID:
PMC12451381.
Multiscale Analysis Reveals Altered Characteristics in Femur and Mandible of Mice on a High Phosphate Diet.
Calcif Tissue Int.
2025 Aug 27;116(1):114. doi: 10.1007/s00223-025-01425-2. PubMed PMID:
40859065; PubMed Central PMCID:
PMC12380639.
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo.
Cell Rep.
2025 Jul 22;44(7):115923. doi: 10.1016/j.celrep.2025.115923. Epub 2025 Jul 3. PubMed PMID:
40614256; PubMed Central PMCID:
PMC12333044.
AIMP3 maintains cardiac homeostasis by regulating the editing activity of methionyl-tRNA synthetase.
Nat Cardiovasc Res.
2025 Jul;4(7):876-890. doi: 10.1038/s44161-025-00670-w. Epub 2025 Jun 25. PubMed PMID:
40562875; PubMed Central PMCID:
PMC12259467.
Differential regulation during development, aging, and disease implies heart cell specific functions of the Mediator Complex.
J Mol Cell Cardiol Plus.
2025 Jun;12:100456. doi: 10.1016/j.jmccpl.2025.100456. eCollection 2025 Jun. PubMed PMID:
40510693; PubMed Central PMCID:
PMC12162080.
A partial loss-of-function variant (Ile191Val) of the TAS1R2 glucose receptor is associated with enhanced responses to exercise training in older adults with obesity: A translational study.
Metabolism.
2025 Jan;162:156045. doi: 10.1016/j.metabol.2024.156045. Epub 2024 Oct 10. PubMed PMID:
39393515; PubMed Central PMCID:
PMC11637915.
Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.
Front Cell Dev Biol.
2024;12:1331563. doi: 10.3389/fcell.2024.1331563. eCollection 2024. PubMed PMID:
38690566; PubMed Central PMCID:
PMC11058648.
Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism.
Circulation.
2024 Apr 16;149(16):1319-1322. doi: 10.1161/CIRCULATIONAHA.123.066473. Epub 2024 Apr 15. PubMed PMID:
38620081; PubMed Central PMCID:
PMC11882014.
Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration.
J Nutr.
2024 Mar;154(3):856-865. doi: 10.1016/j.tjnut.2023.12.037. Epub 2023 Dec 30. PubMed PMID:
38160803.
Dietary fatty acids differentially impact phagocytosis, inflammatory gene expression, and mitochondrial respiration in microglial and neuronal cell models.
Front Cell Neurosci.
2023;17:1227241. doi: 10.3389/fncel.2023.1227241. eCollection 2023. PubMed PMID:
37636589; PubMed Central PMCID:
PMC10448530.
Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity.
J Biol Chem.
2023 Aug;299(8):104917. doi: 10.1016/j.jbc.2023.104917. Epub 2023 Jun 12. PubMed PMID:
37315788; PubMed Central PMCID:
PMC10393818.
The translation initiation factor homolog eif4e1c regulates cardiomyocyte metabolism and proliferation during heart regeneration.
Development.
2023 Oct 15;150(20). doi: 10.1242/dev.201376. Epub 2023 Jun 12. PubMed PMID:
37306388; PubMed Central PMCID:
PMC10281269.
Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study.
Arthritis Res Ther.
2023 May 20;25(1):85. doi: 10.1186/s13075-023-03065-z. PubMed PMID:
37210569; PubMed Central PMCID:
PMC10199606.
Linoleic Acid-Enriched Diet Increases Mitochondrial Tetralinoleoyl Cardiolipin, OXPHOS Protein Levels, and Uncoupling in Interscapular Brown Adipose Tissue during Diet-Induced Weight Gain.
Biology (Basel).
2022 Dec 21;12(1). doi: 10.3390/biology12010009. PubMed PMID:
36671702; PubMed Central PMCID:
PMC9854875.
Editorial: Metabolic regulation in cardiovascular homeostasis and disease.
Front Cardiovasc Med.
2022;9:995207. doi: 10.3389/fcvm.2022.995207. eCollection 2022. PubMed PMID:
35990953; PubMed Central PMCID:
PMC9382290.
Distinct Effects of High-Fat and High-Phosphate Diet on Glucose Metabolism and the Response to Voluntary Exercise in Male Mice.
Nutrients.
2022 Mar 12;14(6). doi: 10.3390/nu14061201. PubMed PMID:
35334860; PubMed Central PMCID:
PMC8951123.
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Mol Metab.
2021 Dec;54:101343. doi: 10.1016/j.molmet.2021.101343. Epub 2021 Sep 25. PubMed PMID:
34583010; PubMed Central PMCID:
PMC8529557.
Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis.
Mol Metab.
2021 Feb;44:101133. doi: 10.1016/j.molmet.2020.101133. Epub 2020 Nov 30. PubMed PMID:
33271332; PubMed Central PMCID:
PMC7785956.
Effects of Exercise to Improve Cardiovascular Health.
Front Cardiovasc Med.
2019;6:69. doi: 10.3389/fcvm.2019.00069. eCollection 2019. Review. PubMed PMID:
31214598; PubMed Central PMCID:
PMC6557987.
High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice.
Circulation.
2019 Mar 12;139(11):1422-1434. doi: 10.1161/CIRCULATIONAHA.118.037550. PubMed PMID:
30612451; PubMed Central PMCID:
PMC6411426.
MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.
Cell Rep.
2018 Jun 26;23(13):3701-3709. doi: 10.1016/j.celrep.2018.05.058. PubMed PMID:
29949755; PubMed Central PMCID:
PMC6066340.
MED12 regulates a transcriptional network of calcium-handling genes in the heart.
JCI Insight.
2017 Jul 20;2(14). doi: 10.1172/jci.insight.91920. eCollection 2017 Jul 20. PubMed PMID:
28724790; PubMed Central PMCID:
PMC5518564.
CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.
Sci Adv.
2017 Apr;3(4):e1602814. doi: 10.1126/sciadv.1602814. eCollection 2017 Apr. PubMed PMID:
28439558; PubMed Central PMCID:
PMC5389745.
A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.
Genes Dev.
2016 Feb 15;30(4):434-46. doi: 10.1101/gad.273128.115. PubMed PMID:
26883362; PubMed Central PMCID:
PMC4762428.
Muscle as a "mediator" of systemic metabolism.
Cell Metab.
2015 Feb 3;21(2):237-248. doi: 10.1016/j.cmet.2014.12.021. Review. PubMed PMID:
25651178; PubMed Central PMCID:
PMC4398026.
MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver.
EMBO Mol Med.
2014 Dec;6(12):1610-21. doi: 10.15252/emmm.201404218. PubMed PMID:
25422356; PubMed Central PMCID:
PMC4287978.
Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in vascular smooth muscle cells.
J Biol Chem.
2014 May 16;289(20):14075-88. doi: 10.1074/jbc.M113.499277. Epub 2014 Apr 7. PubMed PMID:
24711452; PubMed Central PMCID:
PMC4022877.
MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart.
J Mol Cell Cardiol.
2014 Jul;72:168-76. doi: 10.1016/j.yjmcc.2014.03.006. Epub 2014 Mar 18. PubMed PMID:
24650875; PubMed Central PMCID:
PMC4037330.
The heart-liver metabolic axis: defective communication exacerbates disease.
EMBO Mol Med.
2014 Apr;6(4):436-8. doi: 10.1002/emmm.201303800. Epub 2014 Mar 12. PubMed PMID:
24623378; PubMed Central PMCID:
PMC3992070.
AMP-activated protein kinase regulates E3 ligases in rodent heart.
Circ Res.
2011 Oct 28;109(10):1153-61. doi: 10.1161/CIRCRESAHA.111.252742. Epub 2011 Sep 15. PubMed PMID:
21921267; PubMed Central PMCID:
PMC3254015.
An expanded role for AMP-activated protein kinase: regulator of myocardial protein degradation.
Trends Cardiovasc Med.
2011 May;21(4):124-7. doi: 10.1016/j.tcm.2012.03.010. Review. PubMed PMID:
22681968; PubMed Central PMCID:
PMC3372865.
Taking pressure off the heart: the ins and outs of atrophic remodelling.
Cardiovasc Res.
2011 May 1;90(2):243-50. doi: 10.1093/cvr/cvr060. Epub 2011 Feb 25. Review. PubMed PMID:
21354996; PubMed Central PMCID:
PMC3115281.
Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart.
Biochem Biophys Res Commun.
2006 Apr 7;342(2):361-4. doi: 10.1016/j.bbrc.2006.01.163. Epub 2006 Feb 8. PubMed PMID:
16483544.
Cryopreserved morulae can be used to efficiently generate germline-transmitting chimeras by blastocyst injection.
Transgenic Res.
2005 Oct;14(5):685-90. doi: 10.1007/s11248-005-7022-6. PubMed PMID:
16245159.
Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration.
The Journal of nutrition. . NIHMSID: NIHMS2144184.
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