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Kochav JD, Kim J, Judd R, Tak KA, Janjua E, Maciejewski AJ, Kim HW, Klem I, Heitner J, Shah D, Zoghbi WA, Shenoy C, Farzaneh-Far A, Polsani V, Villar-Calle P, Parker M, Judd KM, Khalique OK, Leon MB, Devereux RB, Levine RA, Kim RJ, Weinsaft JW. Myocardial Contractile Mechanics in Ischemic Mitral Regurgitation: Multicenter Data Using Stress Perfusion Cardiovascular Magnetic Resonance. JACC Cardiovasc Imaging. 2022 Jul;15(7):1212-1226. doi: 10.1016/j.jcmg.2022.03.014. Epub 2022 May 11. PubMed PMID: 35798397; PubMed Central PMCID: PMC9273017.
Buffolo F, Monticone S, Camussi G, Aikawa E. Role of Extracellular Vesicles in the Pathogenesis of Vascular Damage. Hypertension. 2022 May;79(5):863-873. doi: 10.1161/HYPERTENSIONAHA.121.17957. Epub 2022 Feb 11. Review. PubMed PMID: 35144490; PubMed Central PMCID: PMC9010370.
Nagata Y, Bertrand PB, Levine RA. Malignant Mitral Valve Prolapse: Risk and Prevention of Sudden Cardiac Death. Curr Treat Options Cardiovasc Med. 2022 May;24(5):61-86. doi: 10.1007/s11936-022-00956-3. Epub 2022 Mar 22. PubMed PMID: 35784809; PubMed Central PMCID: PMC9241643.
Passos LSA, Jha PK, Becker-Greene D, Blaser MC, Romero D, Lupieri A, Sukhova GK, Libby P, Singh SA, Dutra WO, Aikawa M, Levine RA, Nunes MCP, Aikawa E. Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease. Circulation. 2022 Feb 15;145(7):531-548. doi: 10.1161/CIRCULATIONAHA.121.057301. Epub 2022 Feb 14. PubMed PMID: 35157519; PubMed Central PMCID: PMC8869797.
Seebauer CT, Graus MS, Huang L, McCann A, Wylie-Sears J, Fontaine F, Karnezis T, Zurakowski D, Staffa SJ, Meunier F, Mulliken JB, Bischoff J, Francois M. Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma. J Clin Invest. 2022 Feb 1;132(3). doi: 10.1172/JCI151109. PubMed PMID: 34874911; PubMed Central PMCID: PMC8803322.
Huang L, Bichsel C, Norris AL, Thorpe J, Pevsner J, Alexandrescu S, Pinto A, Zurakowski D, Kleiman RJ, Sahin M, Greene AK, Bischoff J. Endothelial GNAQ p.R183Q Increases ANGPT2 (Angiopoietin-2) and Drives Formation of Enlarged Blood Vessels. Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):e27-e43. doi: 10.1161/ATVBAHA.121.316651. Epub 2021 Oct 21. PubMed PMID: 34670408; PubMed Central PMCID: PMC8702487.
Zhang H, Chen ZB, Fredman G, Gomez D, Grumbach IM, Huang NF, Nguyen PKP, Ouimet M, Sutton NR, Aikawa E. What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award. Arterioscler Thromb Vasc Biol. 2021 Nov;41(11):2641-2647. doi: 10.1161/ATVBAHA.121.316558. Epub 2021 Sep 22. Review. PubMed PMID: 34547925; PubMed Central PMCID: PMC8551033.
Alvandi Z, Bischoff J. Endothelial-Mesenchymal Transition in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2357-2369. doi: 10.1161/ATVBAHA.121.313788. Epub 2021 Jul 1. Review. PubMed PMID: 34196216; PubMed Central PMCID: PMC8387428.
Lupieri A, Nagata Y, Passos LSA, Beker-Greene D, Kirkwood KA, Wylie-Sears J, Alvandi Z, Higashi H, Hung JW, Singh SA, Bischoff J, Levine RA, Aikawa E. Integration of Functional Imaging, Cytometry, and Unbiased Proteomics Reveals New Features of Endothelial-to-Mesenchymal Transition in Ischemic Mitral Valve Regurgitation in Human Patients. Front Cardiovasc Med. 2021;8:688396. doi: 10.3389/fcvm.2021.688396. eCollection 2021. PubMed PMID: 34458332; PubMed Central PMCID: PMC8387660.
Bartoli-Leonard F, Aikawa E. Recapitulating the Complex Pathology of Atherosclerosis: Which Model to Use?. Circ Res. 2021 Aug 6;129(4):491-493. doi: 10.1161/CIRCRESAHA.121.319721. Epub 2021 Aug 5. PubMed PMID: 34351800; PubMed Central PMCID: PMC8352010.
Greene AK, Sudduth CL. Vascular Malformations: Current Progress Toward Drug Therapy. J Craniofac Surg. 2021 May 1;32(Suppl 3):1211-1215. doi: 10.1097/SCS.0000000000007310. PubMed PMID: 33273196; PubMed Central PMCID: PMC8175078.
Blaser MC, Kraler S, Lüscher TF, Aikawa E. Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. Circ Res. 2021 Apr 30;128(9):1371-1397. doi: 10.1161/CIRCRESAHA.120.317979. Epub 2021 Apr 29. Review. PubMed PMID: 33914608; PubMed Central PMCID: PMC8095729.
Levine RA, Nagata Y. Imaging Cardiac Valve Mechanics: A New Frontier. JACC Cardiovasc Imaging. 2021 Apr;14(4):794-796. doi: 10.1016/j.jcmg.2021.03.002. PubMed PMID: 33832662; NIHMSID:NIHMS1717274.
Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR. NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma. JCI Insight. 2021 Feb 8;6(3). doi: 10.1172/jci.insight.142299. PubMed PMID: 33400686; PubMed Central PMCID: PMC7934876.
Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, Brophy ML, Liu X, Wylie-Sears J, Wu H, Wong S, Cui G, Kawashima Y, Matsumoto H, Kodera Y, Wojcikiewicz RJH, Srivastava S, Bischoff J, Wang DZ, Ley K, Chen H. Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nat Commun. 2020 Aug 7;11(1):3984. doi: 10.1038/s41467-020-17848-4. PubMed PMID: 32770009; PubMed Central PMCID: PMC7414107.
Yang LT, Ahn SW, Li Z, Benfari G, Mankad R, Takeuchi M, Levine RA, Enriquez-Sarano M, Michelena HI. Mitral Valve Prolapse Patients with Less than Moderate Mitral Regurgitation Exhibit Early Cardiac Chamber Remodeling. J Am Soc Echocardiogr. 2020 Jul;33(7):815-825.e2. doi: 10.1016/j.echo.2020.01.016. Epub 2020 Mar 26. PubMed PMID: 32222479; PubMed Central PMCID: PMC8193998.
Goss JA, Konczyk DJ, Smits P, Sudduth CL, Bischoff J, Liang MG, Greene AK. Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants. Clin Genet. 2020 May;97(5):736-740. doi: 10.1111/cge.13702. Epub 2020 Jan 27. PubMed PMID: 31909475; PubMed Central PMCID: PMC8128061.
Marsit O, Clavel MA, Côté-Laroche C, Hadjadj S, Bouchard MA, Handschumacher MD, Clisson M, Drolet MC, Boulanger MC, Kim DH, Guerrero JL, Bartko PE, Couet J, Arsenault M, Mathieu P, Pibarot P, Aïkawa E, Bischoff J, Levine RA, Beaudoin J. Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction. J Am Coll Cardiol. 2020 Feb 4;75(4):395-405. doi: 10.1016/j.jacc.2019.11.039. PubMed PMID: 32000951; PubMed Central PMCID: PMC7946170.
Huang L, Bischoff J. Isolation of Stem Cells, Endothelial Cells and Pericytes from Human Infantile Hemangioma. Bio Protoc. 2020 Jan 20;10(2):e3487. doi: 10.21769/BioProtoc.3487. eCollection 2020 Jan 20. PubMed PMID: 33654720; PubMed Central PMCID: PMC7842308.
Griffioen AW, Bischoff J. Oxygen sensing decoded: a Nobel concept in biology. Angiogenesis. 2019 Nov;22(4):471-472. doi: 10.1007/s10456-019-09692-y. PubMed PMID: 31673842.
Overman J, Fontaine F, Wylie-Sears J, Moustaqil M, Huang L, Meurer M, Chiang IK, Lesieur E, Patel J, Zuegg J, Pasquier E, Sierecki E, Gambin Y, Hamdan M, Khosrotehrani K, Andelfinger G, Bischoff J, Francois M. R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma. Elife. 2019 Jul 30;8. doi: 10.7554/eLife.43026. PubMed PMID: 31358114; PubMed Central PMCID: PMC6667216.
Bichsel C, Bischoff J. A somatic missense mutation in GNAQ causes capillary malformation. Curr Opin Hematol. 2019 May;26(3):179-184. doi: 10.1097/MOH.0000000000000500. Review. PubMed PMID: 30870248; PubMed Central PMCID: PMC8142900.
Kim DH, Heo R, Handschumacher MD, Lee S, Choi YS, Kim KR, Shin Y, Park HK, Bischoff J, Aikawa E, Song JM, Kang DH, Levine RA, Song JK. Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation. JACC Cardiovasc Imaging. 2019 Apr;12(4):665-677. doi: 10.1016/j.jcmg.2017.09.013. Epub 2017 Dec 13. PubMed PMID: 29248661; PubMed Central PMCID: PMC5993562.
Hammoudi N, Watanabe S, Bikou O, Ceccaldi A, Fish K, Yamada KP, Miyashita S, Lebreton G, Hajjar RJ, Ishikawa K. Speckle-Tracking Echocardiographic Strain Analysis Reliably Estimates Degree of Acute LV Unloading During Mechanical LV Support by Impella. J Cardiovasc Transl Res. 2019 Apr;12(2):135-141. doi: 10.1007/s12265-018-9812-2. Epub 2018 May 29. PubMed PMID: 29845440; PubMed Central PMCID: PMC6692910.
Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H. Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation. Circ Res. 2019 Feb 15;124(4):e6-e19. doi: 10.1161/CIRCRESAHA.118.313028. PubMed PMID: 30595089; PubMed Central PMCID: PMC6375743.
Toomer K, Sauls K, Fulmer D, Guo L, Moore K, Glover J, Stairley R, Bischoff J, Levine RA, Norris RA. Filamin-A as a Balance between Erk/Smad Activities During Cardiac Valve Development. Anat Rec (Hoboken). 2019 Jan;302(1):117-124. doi: 10.1002/ar.23911. Epub 2018 Oct 5. PubMed PMID: 30288957; PubMed Central PMCID: PMC6312478.
Bichsel CA, Goss J, Alomari M, Alexandrescu S, Robb R, Smith LE, Hochman M, Greene AK, Bischoff J. Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma. JAMA Ophthalmol. 2019 Jan 1;137(1):91-95. doi: 10.1001/jamaophthalmol.2018.5141. PubMed PMID: 30422215; PubMed Central PMCID: PMC6382586.
Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H. Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes. J Clin Invest. 2018 Aug 31;128(9):4025-4043. doi: 10.1172/JCI96063. Epub 2018 Aug 13. PubMed PMID: 30102256; PubMed Central PMCID: PMC6118634.
Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review. PubMed PMID: 29766399; PubMed Central PMCID: PMC6237663.
Bischoff J. PTEN (Phosphatase and Tensin Homolog) Connection in Hereditary Hemorrhagic Telangiectasia 2. Arterioscler Thromb Vasc Biol. 2018 May;38(5):984-985. doi: 10.1161/ATVBAHA.118.310921. PubMed PMID: 29695532; PubMed Central PMCID: PMC6636313.
Kim DH, Dal-Bianco JP, Aikawa E, Bischoff J, Levine RA. Mitral Valve Adaptation: Can We Win the Race?. Circ Cardiovasc Imaging. 2018 Apr;11(4):e007642. doi: 10.1161/CIRCIMAGING.118.007642. PubMed PMID: 29626080; PubMed Central PMCID: PMC5890943.
Beaudoin J, Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Sullivan S, Bartko PE, Handschumacher MD, Kim DH, Wylie-Sears J, Aaron J, Levine RA. Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling. Circ Cardiovasc Imaging. 2017 Nov;10(11). doi: 10.1161/CIRCIMAGING.117.006512. PubMed PMID: 29042413; PubMed Central PMCID: PMC5683411.
Bartko PE, Dal-Bianco JP, Guerrero JL, Beaudoin J, Szymanski C, Kim DH, Seybolt MM, Handschumacher MD, Sullivan S, Garcia ML, Titus JS, Wylie-Sears J, Irvin WS, Messas E, Hagège AA, Carpentier A, Aikawa E, Bischoff J, Levine RA. Effect of Losartan on Mitral Valve Changes After Myocardial Infarction. J Am Coll Cardiol. 2017 Sep 5;70(10):1232-1244. doi: 10.1016/j.jacc.2017.07.734. PubMed PMID: 28859786; PubMed Central PMCID: PMC5679094.
Couto JA, Ayturk UM, Konczyk DJ, Goss JA, Huang AY, Hann S, Reeve JL, Liang MG, Bischoff J, Warman ML, Greene AK. A somatic GNA11 mutation is associated with extremity capillary malformation and overgrowth. Angiogenesis. 2017 Aug;20(3):303-306. doi: 10.1007/s10456-016-9538-1. Epub 2017 Jan 24. PubMed PMID: 28120216; PubMed Central PMCID: PMC5511772.
Kang KT, Lin RZ, Kuppermann D, Melero-Martin JM, Bischoff J. Endothelial colony forming cells and mesenchymal progenitor cells form blood vessels and increase blood flow in ischemic muscle. Sci Rep. 2017 Apr 10;7(1):770. doi: 10.1038/s41598-017-00809-1. PubMed PMID: 28396600; PubMed Central PMCID: PMC5429692.
Huang L, Couto JA, Pinto A, Alexandrescu S, Madsen JR, Greene AK, Sahin M, Bischoff J. Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in Sturge-Weber Syndrome. Pediatr Neurol. 2017 Feb;67:59-63. doi: 10.1016/j.pediatrneurol.2016.10.010. Epub 2016 Oct 21. PubMed PMID: 27919468; PubMed Central PMCID: PMC5303551.
Bischoff J, Casanovas G, Wylie-Sears J, Kim DH, Bartko PE, Guerrero JL, Dal-Bianco JP, Beaudoin J, Garcia ML, Sullivan SM, Seybolt MM, Morris BA, Keegan J, Irvin WS, Aikawa E, Levine RA. CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction. Circ Res. 2016 Nov 11;119(11):1215-1225. doi: 10.1161/CIRCRESAHA.116.309598. Epub 2016 Oct 6. PubMed PMID: 27750208; PubMed Central PMCID: PMC5215059.
Bai S, Ingram P, Chen YC, Deng N, Pearson A, Niknafs YS, O'Hayer P, Wang Y, Zhang ZY, Boscolo E, Bischoff J, Yoon E, Buckanovich RJ. EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells. Cancer Res. 2016 Nov 1;76(21):6396-6409. doi: 10.1158/0008-5472.CAN-16-0225. PubMed PMID: 27803106; PubMed Central PMCID: PMC5120866.
Ayturk UM, Couto JA, Hann S, Mulliken JB, Williams KL, Huang AY, Fishman SJ, Boyd TK, Kozakewich HPW, Bischoff J, Greene AK, Warman ML. Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma. Am J Hum Genet. 2016 Jun 2;98(6):1271. doi: 10.1016/j.ajhg.2016.05.010. Epub 2016 Jun 2. PubMed PMID: 27259057; PubMed Central PMCID: PMC4908183.
Ye X, Abou-Rayyah Y, Bischoff J, Ritchie A, Sebire NJ, Watts P, Churchill AJ, Bates DO. Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma. J Pathol. 2016 Jun;239(2):139-51. doi: 10.1002/path.4715. PubMed PMID: 26957058; PubMed Central PMCID: PMC4869683.
Dal-Bianco JP, Bartko PE, Beaudoin J, Aikawa E, Bischoff J, Levine RA. 3D Ultrasound: seeing is understanding-from imaging to pathophysiology to developing therapies in secondary MR. Eur Heart J Cardiovasc Imaging. 2016 May;17(5):510-1. doi: 10.1093/ehjci/jew029. Epub 2016 Mar 13. PubMed PMID: 26976355; PubMed Central PMCID: PMC4829123.
Ayturk UM, Couto JA, Hann S, Mulliken JB, Williams KL, Huang AY, Fishman SJ, Boyd TK, Kozakewich HP, Bischoff J, Greene AK, Warman ML. Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma. Am J Hum Genet. 2016 Apr 7;98(4):789-95. doi: 10.1016/j.ajhg.2016.03.009. PubMed PMID: 27058448; PubMed Central PMCID: PMC4833432.
Rossi E, Smadja DM, Boscolo E, Langa C, Arevalo MA, Pericacho M, Gamella-Pozuelo L, Kauskot A, Botella LM, Gaussem P, Bischoff J, Lopez-Novoa JM, Bernabeu C. Endoglin regulates mural cell adhesion in the circulatory system. Cell Mol Life Sci. 2016 Apr;73(8):1715-39. doi: 10.1007/s00018-015-2099-4. Epub 2015 Dec 8. PubMed PMID: 26646071; PubMed Central PMCID: PMC4805714.
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Hjortnaes J, Beaudoin J, Szymanski C, Bartko PE, Seybolt MM, Handschumacher MD, Sullivan S, Garcia ML, Mauskapf A, Titus JS, Wylie-Sears J, Irvin WS, Chaput M, Messas E, Hagège AA, Carpentier A, Levine RA. Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve. J Am Coll Cardiol. 2016 Jan 26;67(3):275-87. doi: 10.1016/j.jacc.2015.10.092. PubMed PMID: 26796392; PubMed Central PMCID: PMC5099077.
Couto JA, Huang L, Vivero MP, Kamitaki N, Maclellan RA, Mulliken JB, Bischoff J, Warman ML, Greene AK. Endothelial Cells from Capillary Malformations Are Enriched for Somatic GNAQ Mutations. Plast Reconstr Surg. 2016 Jan;137(1):77e-82e. doi: 10.1097/PRS.0000000000001868. PubMed PMID: 26368330; PubMed Central PMCID: PMC5242181.
Yu CW, Liang X, Lipsky S, Karaaslan C, Kozakewich H, Hotamisligil GS, Bischoff J, Cataltepe S. Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses. Angiogenesis. 2016 Jan;19(1):95-106. doi: 10.1007/s10456-015-9491-4. Epub 2015 Dec 1. PubMed PMID: 26625874; PubMed Central PMCID: PMC5674139.
Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, Delling FN, Dietz HC, Dina C, Durst R, Fernandez-Friera L, Handschumacher MD, Jensen MO, Jeunemaitre XP, Le Marec H, Le Tourneau T, Markwald RR, Mérot J, Messas E, Milan DP, Neri T, Norris RA, Peal D, Perrocheau M, Probst V, Pucéat M, Rosenthal N, Solis J, Schott JJ, Schwammenthal E, Slaugenhaupt SA, Song JK, Yacoub MH. Mitral valve disease--morphology and mechanisms. Nat Rev Cardiol. 2015 Dec;12(12):689-710. doi: 10.1038/nrcardio.2015.161. Epub 2015 Oct 20. Review. PubMed PMID: 26483167; PubMed Central PMCID: PMC4804623.
Smadja DM, Levy M, Huang L, Rossi E, Blandinières A, Israel-Biet D, Gaussem P, Bischoff J. Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells. Thromb Haemost. 2015 Oct;114(4):735-47. doi: 10.1160/TH14-11-0907. Epub 2015 Jun 11. PubMed PMID: 26062754; PubMed Central PMCID: PMC6570989.
Hjortnaes J, Shapero K, Goettsch C, Hutcheson JD, Keegan J, Kluin J, Mayer JE, Bischoff J, Aikawa E. Valvular interstitial cells suppress calcification of valvular endothelial cells. Atherosclerosis. 2015 Sep;242(1):251-260. doi: 10.1016/j.atherosclerosis.2015.07.008. Epub 2015 Jul 17. PubMed PMID: 26232165; PubMed Central PMCID: PMC4546848.
Boscolo E, Limaye N, Huang L, Kang KT, Soblet J, Uebelhoer M, Mendola A, Natynki M, Seront E, Dupont S, Hammer J, Legrand C, Brugnara C, Eklund L, Vikkula M, Bischoff J, Boon LM. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects. J Clin Invest. 2015 Sep;125(9):3491-504. doi: 10.1172/JCI76004. Epub 2015 Aug 10. PubMed PMID: 26258417; PubMed Central PMCID: PMC4588237.
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