Inflammatory Alterations to Renal Lymphatic Endothelial Cell Gene Expression in Mouse Models of Hypertension.
Kidney Blood Press Res.
2024;49(1):588-604. doi: 10.1159/000539721. Epub 2024 Jul 22. PubMed PMID:
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Spatiotemporal Landscape of Kidney Tubular Responses to Glomerular Proteinuria.
J Am Soc Nephrol.
2024 Jul 1;35(7):854-869. doi: 10.1681/ASN.0000000000000357. Epub 2024 Apr 23. PubMed PMID:
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Single-Cell RNA Sequencing Identifies Response of Renal Lymphatic Endothelial Cells to Acute Kidney Injury.
J Am Soc Nephrol.
2024 May 1;35(5):549-565. doi: 10.1681/ASN.0000000000000325. Epub 2024 Feb 7. PubMed PMID:
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Sodium, Interstitium, Lymphatics and Hypertension-A Tale of Hydraulics.
Hypertension.
2024 Apr;81(4):727-737. doi: 10.1161/HYPERTENSIONAHA.123.17942. Epub 2024 Feb 22. Review. PubMed PMID:
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VEGFR-3 signaling in macrophages: friend or foe in disease?.
Front Immunol.
2024;15:1349500. doi: 10.3389/fimmu.2024.1349500. eCollection 2024. Review. PubMed PMID:
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Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization.
Nat Commun.
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Evolution of hypoxia and hypoxia-inducible factor asparaginyl hydroxylase regulation in chronic kidney disease.
Nephrol Dial Transplant.
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Single-cell RNA sequencing identifies response of renal lymphatic endothelial cells to acute kidney injury.
bioRxiv.
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PCK1 is a key regulator of metabolic and mitochondrial functions in renal tubular cells.
Am J Physiol Renal Physiol.
2023 Jun 1;324(6):F532-F543. doi: 10.1152/ajprenal.00038.2023. Epub 2023 Apr 27. PubMed PMID:
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Indole Propionic Acid Increases T Regulatory Cells and Decreases T Helper 17 Cells and Blood Pressure in Mice with Salt-Sensitive Hypertension.
Int J Mol Sci.
2023 May 24;24(11). doi: 10.3390/ijms24119192. PubMed PMID:
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Lymphatic Pathophysiology.
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2023 Apr;30(2-3):e12806. doi: 10.1111/micc.12806. PubMed PMID:
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Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model.
Mol Metab.
2023 Mar;69:101680. doi: 10.1016/j.molmet.2023.101680. Epub 2023 Jan 22. PubMed PMID:
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Increased adipose tissue lymphatic vessel density inhibits thermogenesis through elevated neurotensin levels.
Front Cell Dev Biol.
2023;11:1100788. doi: 10.3389/fcell.2023.1100788. eCollection 2023. PubMed PMID:
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Genetically inducing renal lymphangiogenesis attenuates hypertension in mice.
Clin Sci (Lond).
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Oxidized low density lipoprotein in the liver causes decreased permeability of liver lymphatic- but not liver sinusoidal-endothelial cells via VEGFR-3 regulation of VE-Cadherin.
Front Physiol.
2022;13:1021038. doi: 10.3389/fphys.2022.1021038. eCollection 2022. PubMed PMID:
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Indications of Peripheral Pain, Dermal Hypersensitivity, and Neurogenic Inflammation in Patients with Lipedema.
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Impact of High Fat Diet and Bolus Feeding on Chyle Accumulation in a Mouse Model of Generalized Lymphatic Anomaly.
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Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis.
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Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease.
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Evaluation of the Cardiometabolic Disorders after Spinal Cord Injury in Mice.
Biology (Basel).
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A Kidney-Targeted Nanoparticle to Augment Renal Lymphatic Density Decreases Blood Pressure in Hypertensive Mice.
Pharmaceutics.
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Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress.
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Expanded renal lymphatics improve recovery following kidney injury.
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Common Metabolites in Two Different Hypertensive Mouse Models: A Serum and Urine Metabolome Study.
Biomolecules.
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Fixing lymphatics improves glucose metabolism.
Nat Metab.
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Dichotomous effects on lymphatic transport with loss of caveolae in mice.
Acta Physiol (Oxf).
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Emerging roles for lymphatics in acute kidney injury: Beneficial or maleficent?.
Exp Biol Med (Maywood).
2021 Apr;246(7):845-850. doi: 10.1177/1535370220983235. Epub 2021 Jan 19. PubMed PMID:
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Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney disease.
Nephrol Dial Transplant.
2021 Jan 1;36(1):60-68. doi: 10.1093/ndt/gfaa124. PubMed PMID:
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Hypertension and reproductive dysfunction: a possible role of inflammation and inflammation-associated lymphangiogenesis in gonads.
Clin Sci (Lond).
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Kidney-specific lymphangiogenesis increases sodium excretion and lowers blood pressure in mice.
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Characterizing Lymphangiogenesis and Concurrent Inflammation in Adipose Tissue in Response to VEGF-D.
Front Physiol.
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Time-course of sodium transport along the nephron in nephrotic syndrome: The role of potassium.
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Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
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Augmenting Renal Lymphatic Density Prevents Angiotensin II-Induced Hypertension in Male and Female Mice.
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Reduced lymphatic function contributes to age-related disease.
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Immune cell trafficking, lymphatics and hypertension.
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Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity.
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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State.
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Enhancing Renal Lymphatic Expansion Prevents Hypertension in Mice.
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VEGF-C promotes the development of lymphatics in bone and bone loss.
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Na(v)1.8 neurons are involved in limiting acute phase responses to dietary fat.
Mol Metab.
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Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations.
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Renal inflammation and injury are associated with lymphangiogenesis in hypertension.
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Lymphangiogenesis: fuel, smoke, or extinguisher of inflammation's fire?.
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Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression.
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Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility.
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Hyperplasia, de novo lymphangiogenesis, and lymphatic regression in mice with tissue-specific, inducible overexpression of murine VEGF-D.
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The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia.
Circulation.
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Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.
Cell Metab.
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Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling.
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