My Bibliography

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McCarthy PV, Bhatia AJ, Saw SM, Mosley JD, Vega-Quiñones A. Cigarette smoking and bladder cancer in Washington County, Maryland: ammunition for health educators. Md Med J. 1995 Dec;44(12):1039-42. PubMed PMID: 8544669.

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Mosley JD, Appel LJ, Ashour Z, Coresh J, Whelton PK, Ibrahim MM. Relationship between skin color and blood pressure in egyptian adults: results from the national hypertension project. Hypertension. 2000 Aug;36(2):296-302. doi: 10.1161/01.hyp.36.2.296. PubMed PMID: 10948093.

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Mosley J, Conti DV, Elston RC, Witte JS. Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists. Genet Epidemiol. 2001;21 Suppl 1:S837-42. doi: 10.1002/gepi.2001.21.s1.s837. PubMed PMID: 11793789.

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Silverman EK, Mosley JD, Rao DC, Palmer LJ, Province MA, Elston RC, Weiss ST, Campbell EJ. Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases. Hum Hered. 2001;52(4):223-32. doi: 10.1159/000053380. PubMed PMID: 11713419.

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Ibrahim MM, Appel LJ, Rizk HH, Helmy S, Mosley J, Ashour Z, El-Aroussy W, Roccella E, Whelton P. Cardiovascular risk factors in normotensive and hypertensive Egyptians. J Hypertens. 2001 Nov;19(11):1933-40. doi: 10.1097/00004872-200111000-00002. PubMed PMID: 11677357.

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Celedón JC, Soto-Quiros ME, Palmer LJ, Senter J, Mosley J, Silverman EK, Weiss ST. Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica. Clin Exp Allergy. 2002 Mar;32(3):387-90. doi: 10.1046/j.1365-2222.2002.01348.x. PubMed PMID: 11940068.

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Silverman EK, Mosley JD, Palmer LJ, Barth M, Senter JM, Brown A, Drazen JM, Kwiatkowski DJ, Chapman HA, Campbell EJ, Province MA, Rao DC, Reilly JJ, Ginns LC, Speizer FE, Weiss ST. Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes. Hum Mol Genet. 2002 Mar 15;11(6):623-32. doi: 10.1093/hmg/11.6.623. PubMed PMID: 11912177.

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Silverman EK, Palmer LJ, Mosley JD, Barth M, Senter JM, Brown A, Drazen JM, Kwiatkowski DJ, Chapman HA, Campbell EJ, Province MA, Rao DC, Reilly JJ, Ginns LC, Speizer FE, Weiss ST. Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet. 2002 May;70(5):1229-39. doi: 10.1086/340316. Epub 2002 Mar 25. PubMed PMID: 11914989; PubMed Central PMCID: PMC447597.

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Mosley JD, Keri RA. Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis. Biochem Biophys Res Commun. 2006 Sep 29;348(3):1174-83. doi: 10.1016/j.bbrc.2006.07.176. Epub 2006 Aug 4. PubMed PMID: 16905118; PubMed Central PMCID: PMC1592129.

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Mosley JD, Poirier JT, Seachrist DD, Landis MD, Keri RA. Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. Mol Cancer Ther. 2007 Aug;6(8):2188-97. doi: 10.1158/1535-7163.MCT-07-0235. PubMed PMID: 17699716; PubMed Central PMCID: PMC2562754.

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Mosley JD, Keri RA. Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists. BMC Med Genomics. 2008 Apr 25;1:11. doi: 10.1186/1755-8794-1-11. PubMed PMID: 18439262; PubMed Central PMCID: PMC2396170.

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Mosley JD, Keri RA. Intrinsic bias in breast cancer gene expression data sets. BMC Cancer. 2009 Jun 29;9:214. doi: 10.1186/1471-2407-9-214. PubMed PMID: 19563679; PubMed Central PMCID: PMC2711113.

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Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, Godwin AK, Korach KS, Visvader JE, Kaestner KH, Abdul-Karim FW, Montano MM, Keri RA. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development. 2010 Jun;137(12):2045-54. doi: 10.1242/dev.043299. PubMed PMID: 20501593; PubMed Central PMCID: PMC2875844.

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Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, McCarty CA, Chisholm RL, Kho AN, Carlson CS, Larson EB, Jarvik GP, Sotoodehnia N, Manolio TA, Li R, Masys DR, Haines JL, Roden DM. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation. 2013 Apr 2;127(13):1377-85. doi: 10.1161/CIRCULATIONAHA.112.000604. Epub 2013 Mar 5. PubMed PMID: 23463857; PubMed Central PMCID: PMC3713791.

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Wells QS, Becker JR, Su YR, Mosley JD, Weeke P, D'Aoust L, Ausborn NL, Ramirez AH, Pfotenhauer JP, Naftilan AJ, Markham L, Exil V, Roden DM, Hong CC. Whole exome sequencing identifies a causal RBM20 mutation in a large pedigree with familial dilated cardiomyopathy. Circ Cardiovasc Genet. 2013 Aug;6(4):317-26. doi: 10.1161/CIRCGENETICS.113.000011. Epub 2013 Jul 16. PubMed PMID: 23861363; PubMed Central PMCID: PMC3895490.

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Wei WQ, Mosley JD, Bastarache L, Denny JC. Validation and enhancement of a computable medication indication resource (MEDI) using a large practice-based dataset. AMIA Annu Symp Proc. 2013;2013:1448-56. eCollection 2013. PubMed PMID: 24551419; PubMed Central PMCID: PMC3900157.

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Weeke P, Delaney J, Mosley JD, Wells Q, Van Driest S, Norris K, Kucera G, Stubblefield T, Roden DM. QT variability during initial exposure to sotalol: experience based on a large electronic medical record. Europace. 2013 Dec;15(12):1791-7. doi: 10.1093/europace/eut153. Epub 2013 Jun 19. PubMed PMID: 23787903; PubMed Central PMCID: PMC3888125.

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Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, Rasmussen LV, Crosslin DR, Crane PK, Pathak J, Bielinski SJ, Pendergrass SA, Xu H, Hindorff LA, Li R, Manolio TA, Chute CG, Chisholm RL, Larson EB, Jarvik GP, Brilliant MH, McCarty CA, Kullo IJ, Haines JL, Crawford DC, Masys DR, Roden DM. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat Biotechnol. 2013 Dec;31(12):1102-10. doi: 10.1038/nbt.2749. PubMed PMID: 24270849; PubMed Central PMCID: PMC3969265.

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Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM. Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. PLoS One. 2013;8(12):e81503. doi: 10.1371/journal.pone.0081503. eCollection 2013. PubMed PMID: 24349080; PubMed Central PMCID: PMC3861317.

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Karnes JH, Van Driest S, Bowton EA, Weeke PE, Mosley JD, Peterson JF, Denny JC, Roden DM. Using systems approaches to address challenges for clinical implementation of pharmacogenomics. Wiley Interdiscip Rev Syst Biol Med. 2014 Mar-Apr;6(2):125-35. doi: 10.1002/wsbm.1255. Epub 2013 Dec 6. Review. PubMed PMID: 24319008; PubMed Central PMCID: PMC3944797.

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Weeke P, Mosley JD, Hanna D, Delaney JT, Shaffer C, Wells QS, Van Driest S, Karnes JH, Ingram C, Guo Y, Shyr Y, Norris K, Kannankeril PJ, Ramirez AH, Smith JD, Mardis ER, Nickerson D, George AL Jr, Roden DM. Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome. J Am Coll Cardiol. 2014 Apr 15;63(14):1430-7. doi: 10.1016/j.jacc.2014.01.031. Epub 2014 Feb 19. PubMed PMID: 24561134; PubMed Central PMCID: PMC4018823.

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Bowton E, Field JR, Wang S, Schildcrout JS, Van Driest SL, Delaney JT, Cowan J, Weeke P, Mosley JD, Wells QS, Karnes JH, Shaffer C, Peterson JF, Denny JC, Roden DM, Pulley JM. Biobanks and electronic medical records: enabling cost-effective research. Sci Transl Med. 2014 Apr 30;6(234):234cm3. doi: 10.1126/scitranslmed.3008604. PubMed PMID: 24786321; PubMed Central PMCID: PMC4226414.

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Mosley JD, Van Driest SL, Weeke PE, Delaney JT, Wells QS, Bastarache L, Roden DM, Denny JC. Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations. PLoS One. 2014;9(6):e100322. doi: 10.1371/journal.pone.0100322. eCollection 2014. PubMed PMID: 24949630; PubMed Central PMCID: PMC4065041.

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Yang T, Chun YW, Stroud DM, Mosley JD, Knollmann BC, Hong C, Roden DM. Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current. Circulation. 2014 Jul 15;130(3):224-34. doi: 10.1161/CIRCULATIONAHA.113.007765. Epub 2014 Jun 3. PubMed PMID: 24895457; PubMed Central PMCID: PMC4101031.

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Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, Pathak J, Bielinski SJ, Carrell DS, Crosslin DR, Ledbetter DH, Carey DJ, Tromp G, Williams MS, Larson EB, Jarvik GP, Peissig PL, Brilliant MH, McCarty CA, Chute CG, Kullo IJ, Bottinger E, Chisholm R, Smith ME, Roden DM, Denny JC. Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Front Genet. 2014;5:250. doi: 10.3389/fgene.2014.00250. eCollection 2014. PubMed PMID: 25177340; PubMed Central PMCID: PMC4134007.

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Goswami S, Yee SW, Stocker S, Mosley JD, Kubo M, Castro R, Mefford JA, Wen C, Liang X, Witte J, Brett C, Maeda S, Simpson MD, Hedderson MM, Davis RL, Roden DM, Giacomini KM, Savic RM. Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. 2014 Sep;96(3):370-9. doi: 10.1038/clpt.2014.109. Epub 2014 May 22. PubMed PMID: 24853734; PubMed Central PMCID: PMC4171106.

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Yori JL, Lozada KL, Seachrist DD, Mosley JD, Abdul-Karim FW, Booth CN, Flask CA, Keri RA. Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression. Cancer Res. 2014 Sep 1;74(17):4762-71. doi: 10.1158/0008-5472.CAN-13-3627. Epub 2014 Jul 14. PubMed PMID: 25023728; PubMed Central PMCID: PMC4155007.

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Weeke P, Muhammad R, Delaney JT, Shaffer C, Mosley JD, Blair M, Short L, Stubblefield T, Roden DM, Darbar D. Whole-exome sequencing in familial atrial fibrillation. Eur Heart J. 2014 Sep 21;35(36):2477-83. doi: 10.1093/eurheartj/ehu156. Epub 2014 Apr 11. PubMed PMID: 24727801; PubMed Central PMCID: PMC4169871.

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Karnes JH, Cronin RM, Rollin J, Teumer A, Pouplard C, Shaffer CM, Blanquicett C, Bowton EA, Cowan JD, Mosley JD, Van Driest SL, Weeke PE, Wells QS, Bakchoul T, Denny JC, Greinacher A, Gruel Y, Roden DM. A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record. Thromb Haemost. 2015 Apr;113(4):772-81. doi: 10.1160/TH14-08-0670. Epub 2014 Dec 11. PubMed PMID: 25503805; PubMed Central PMCID: PMC4433536.

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Mosley JD, Brittain EL, Loyd JE, Denny JC, Austin ED, Larkin EK. Letter by Mosley Regarding Article, "Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat". Circ Res. 2015 Aug 28;117(6):e56-7. doi: 10.1161/CIRCRESAHA.115.306867. PubMed PMID: 26316607; PubMed Central PMCID: PMC4557206.

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Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Identifying genetically driven clinical phenotypes using linear mixed models. Nat Commun. 2016 Apr 25;7:11433. doi: 10.1038/ncomms11433. PubMed PMID: 27109359; PubMed Central PMCID: PMC4848547.

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Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, Linneman JG, Brilliant MH, Pacheco JA, Thompson W, Chisholm RL, Jarvik GP, Crosslin DR, Carrell DS, Baldwin E, Ralston J, Larson EB, Grafton J, Scrol A, Jouni H, Kullo IJ, Tromp G, Borthwick KM, Kuivaniemi H, Carey DJ, Ritchie MD, Bradford Y, Verma SS, Chute CG, Veluchamy A, Siddiqui MK, Palmer CN, Doney A, MahmoudPour SH, Maitland-van der Zee AH, Morris AD, Denny JC, Roden DM. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. Pharmacogenomics J. 2016 Jun;16(3):231-7. doi: 10.1038/tpj.2015.51. Epub 2015 Jul 14. PubMed PMID: 26169577; PubMed Central PMCID: PMC4713364.

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Roden DM, Mosley JD, Denny JC. Finding a Needle in a QT Interval Big Data Haystack: The Role for Orthogonal Datasets. J Am Coll Cardiol. 2016 Oct 18;68(16):1765-1768. doi: 10.1016/j.jacc.2016.08.012. PubMed PMID: 27737743.

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Goswami S, Yee SW, Xu F, Sridhar SB, Mosley JD, Takahashi A, Kubo M, Maeda S, Davis RL, Roden DM, Hedderson MM, Giacomini KM, Savic RM. A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin. Clin Pharmacol Ther. 2016 Nov;100(5):537-547. doi: 10.1002/cpt.428. Epub 2016 Sep 23. PubMed PMID: 27415606; PubMed Central PMCID: PMC5534241.

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Mosley JD, van Driest SL, Wells QS, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Denny JC, Roden DM. Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data. Circ Cardiovasc Genet. 2016 Dec;9(6):521-530. doi: 10.1161/CIRCGENETICS.116.001530. Epub 2016 Oct 25. PubMed PMID: 27780847; PubMed Central PMCID: PMC5177499.

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Hoffmann TJ, Passarelli MN, Graff RE, Emami NC, Sakoda LC, Jorgenson E, Habel LA, Shan J, Ranatunga DK, Quesenberry CP, Chao CR, Ghai NR, Aaronson D, Presti J, Nordström T, Wang Z, Berndt SI, Chanock SJ, Mosley JD, Klein RJ, Middha M, Lilja H, Melander O, Kvale MN, Kwok PY, Schaefer C, Risch N, Van Den Eeden SK, Witte JS. Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Nat Commun. 2017 Jan 31;8:14248. doi: 10.1038/ncomms14248. PubMed PMID: 28139693; PubMed Central PMCID: PMC5290311.

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Karnes JH, Shaffer CM, Bastarache L, Gaudieri S, Glazer AM, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Comparison of HLA allelic imputation programs. PLoS One. 2017;12(2):e0172444. doi: 10.1371/journal.pone.0172444. eCollection 2017. PubMed PMID: 28207879; PubMed Central PMCID: PMC5312875.

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Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Witte JS, Denny JC, Roden DM. Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes. Circ Cardiovasc Genet. 2017 Apr;10(2). doi: 10.1161/CIRCGENETICS.116.001482. PubMed PMID: 28416512; PubMed Central PMCID: PMC5434456.

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Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC. Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Sci Transl Med. 2017 May 10;9(389). doi: 10.1126/scitranslmed.aai8708. PubMed PMID: 28490672; PubMed Central PMCID: PMC5563969.

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Wells QS, Veatch OJ, Fessel JP, Joon AY, Levinson RT, Mosley JD, Held EP, Lindsay CS, Shaffer CM, Weeke PE, Glazer AM, Bersell KR, Van Driest SL, Karnes JH, Blair MA, Lagrone LW, Su YR, Bowton EA, Feng Z, Ky B, Lenihan DJ, Fisch MJ, Denny JC, Roden DM. Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults. Pharmacogenet Genomics. 2017 Jul;27(7):247-254. doi: 10.1097/FPC.0000000000000284. PubMed PMID: 28542097; PubMed Central PMCID: PMC5502740.

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Karnes JH, Shaffer CM, Cronin R, Bastarache L, Gaudieri S, James I, Pavlos R, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Influence of Human Leukocyte Antigen (HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors (KIR) Types on Heparin-Induced Thrombocytopenia (HIT). Pharmacotherapy. 2017 Sep;37(9):1164-1171. doi: 10.1002/phar.1983. Epub 2017 Sep 4. PubMed PMID: 28688202; PubMed Central PMCID: PMC5600645.

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Feng Q, Wei WQ, Levinson RT, Mosley JD, Stein CM. Replication and fine-mapping of genetic predictors of lipid traits in African-Americans. J Hum Genet. 2017 Oct;62(10):895-901. doi: 10.1038/jhg.2017.55. Epub 2017 May 25. PubMed PMID: 28539666; PubMed Central PMCID: PMC5612856.

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Carter TC, Hebbring SJ, Liu J, Mosley JD, Shaffer CM, Ivacic LC, Kopitzke S, Stefanski EL, Strenn R, Sundaram ME, Meece J, Brilliant MH, Ferdinands JM, Belongia EA. Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission. J Med Virol. 2018 Mar;90(3):436-446. doi: 10.1002/jmv.24975. Epub 2017 Nov 11. PubMed PMID: 29053189; PubMed Central PMCID: PMC5760323.

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Bastarache L, Hughey JJ, Hebbring S, Marlo J, Zhao W, Ho WT, Van Driest SL, McGregor TL, Mosley JD, Wells QS, Temple M, Ramirez AH, Carroll R, Osterman T, Edwards T, Ruderfer D, Velez Edwards DR, Hamid R, Cogan J, Glazer A, Wei WQ, Feng Q, Brilliant M, Zhao ZJ, Cox NJ, Roden DM, Denny JC. Phenotype risk scores identify patients with unrecognized Mendelian disease patterns. Science. 2018 Mar 16;359(6381):1233-1239. doi: 10.1126/science.aal4043. PubMed PMID: 29590070; PubMed Central PMCID: PMC5959723.

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Roden DM, Van Driest SL, Wells QS, Mosley JD, Denny JC, Peterson JF. Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation. Circ Res. 2018 Apr 27;122(9):1176-1190. doi: 10.1161/CIRCRESAHA.117.310965. Review. PubMed PMID: 29700066; PubMed Central PMCID: PMC5926807.

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Roden DM, Van Driest SL, Mosley JD, Wells QS, Robinson JR, Denny JC, Peterson JF. Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome. Clin Pharmacol Ther. 2018 May;103(5):787-794. doi: 10.1002/cpt.1035. Epub 2018 Mar 13. Review. PubMed PMID: 29377064; PubMed Central PMCID: PMC6134843.

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Denny JC, Mosley JD. Disease Heritability Studies Harness the Healthcare System to Achieve Massive Scale. Cell. 2018 Jun 14;173(7):1568-1570. doi: 10.1016/j.cell.2018.05.053. PubMed PMID: 29906443.

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Mosley JD, Levinson RT, Brittain EL, Gupta DK, Farber-Eger E, Shaffer CM, Denny JC, Roden DM, Wells QS. Clinical Features Associated With Nascent Left Ventricular Diastolic Dysfunction in a Population Aged 40 to 55 Years. Am J Cardiol. 2018 Jun 15;121(12):1552-1557. doi: 10.1016/j.amjcard.2018.02.042. Epub 2018 Mar 13. PubMed PMID: 29627106; PubMed Central PMCID: PMC5975107.

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Feng Q, Wei WQ, Chung CP, Levinson RT, Sundermann AC, Mosley JD, Bastarache L, Ferguson JF, Cox NJ, Roden DM, Denny JC, Linton MF, Edwards DRV, Stein CM. Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. PLoS Med. 2018 Aug;15(8):e1002642. doi: 10.1371/journal.pmed.1002642. eCollection 2018 Aug. PubMed PMID: 30153257; PubMed Central PMCID: PMC6112635.

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Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nat Commun. 2018 Aug 30;9(1):3522. doi: 10.1038/s41467-018-05624-4. PubMed PMID: 30166544; PubMed Central PMCID: PMC6117367.