My Bibliography

select

Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 Sep 14;11(1):4591. doi: 10.1038/s41467-020-18245-7. PubMed PMID: 32929084; PubMed Central PMCID: PMC7490264.

select

Li JJ. Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy. iScience. 2020 Jun 26;23(6):101215. doi: 10.1016/j.isci.2020.101215. Epub 2020 May 30. Review. PubMed PMID: 32512383; PubMed Central PMCID: PMC7260547.

select

Zhang L, Xie B, Qiu Y, Jing D, Zhang J, Duan Y, Li Z, Fan M, He J, Qiu Y, Tan R, Li JJ, Sun LQ. Rab25-Mediated EGFR Recycling Causes Tumor Acquired Radioresistance. iScience. 2020 Apr 24;23(4):100997. doi: 10.1016/j.isci.2020.100997. Epub 2020 Mar 20. PubMed PMID: 32252020; PubMed Central PMCID: PMC7132159.

select

Huang J, Li JJ. Cell repopulation, rewiring metabolism, and immune regulation in cancer radiotherapy. Radiation Medicine and Protection. 2020 March. doi: doi.org/10.1016/j.radmp.2020.02.001.

select

Zhang L, Jing D, Jiang N, Rojalin T, Baehr CM, Zhang D, Xiao W, Wu Y, Cong Z, Li JJ, Li Y, Wang L, Lam KS. Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo. Nat Nanotechnol. 2020 Feb;15(2):145-153. doi: 10.1038/s41565-019-0626-4. Epub 2020 Jan 27. PubMed PMID: 31988501; PubMed Central PMCID: PMC7147967.

select

Liu L, Xie B, Fan M, Candas-Green D, Jiang JX, Wei R, Wang Y, Chen HW, Hu Y, Li JJ. Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade. Dev Cell. 2020 Jan 27;52(2):196-209.e9. doi: 10.1016/j.devcel.2019.11.012. Epub 2019 Dec 19. PubMed PMID: 31866205; PubMed Central PMCID: PMC6996588.

select

Duan Z, Andrews NP, Chen CZ, Fan M, Wang J, Shen J, Li JJ, Chen HW. Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation. Oncol Rep. 2020 Jan;43(1):318-327. doi: 10.3892/or.2019.7418. Epub 2019 Nov 27. PubMed PMID: 31789405; NIHMSID:NIHMS1627704.

select

Huang J, Li JJ. Multiple Dynamics in Tumor Microenvironment Under Radiotherapy. Adv Exp Med Biol. 2020;1263:175-202. doi: 10.1007/978-3-030-44518-8_10. Review. PubMed PMID: 32588328.

select

Han S, Wei R, Zhang X, Jiang N, Fan M, Huang JH, Xie B, Zhang L, Miao W, Butler AC, Coleman MA, Vaughan AT, Wang Y, Chen HW, Liu J, Li JJ. CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer. Front Oncol. 2019;9:1201. doi: 10.3389/fonc.2019.01201. eCollection 2019. PubMed PMID: 31803610; PubMed Central PMCID: PMC6873486.

select

Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 Oct 11;10(1):4621. doi: 10.1038/s41467-019-12529-3. PubMed PMID: 31604910; PubMed Central PMCID: PMC6789042.

select

Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 Jun;24:101189. doi: 10.1016/j.redox.2019.101189. Epub 2019 Apr 9. PubMed PMID: 30986607; PubMed Central PMCID: PMC6463934.

select

Ma D, Liu S, Lal B, Wei S, Wang S, Zhan D, Zhang H, Lee RS, Gao P, Lopez-Bertoni H, Ying M, Li JJ, Laterra J, Wilson MA, Xia S. Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. Cancer Res. 2019 May 15;79(10):2697-2708. doi: 10.1158/0008-5472.CAN-18-3125. Epub 2019 Mar 21. PubMed PMID: 30898840; PubMed Central PMCID: PMC8218246.

select

Xie B, Wang S, Jiang N, Li JJ. Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance. Cancer Lett. 2019 Feb 28;443:56-66. doi: 10.1016/j.canlet.2018.11.019. Epub 2018 Nov 24. Review. PubMed PMID: 30481564; PubMed Central PMCID: PMC6759061.

select

Miao W, Fan M, Huang M, Li JJ, Wang Y. Targeted Profiling of Heat Shock Proteome in Radioresistant Breast Cancer Cells. Chem Res Toxicol. 2019 Feb 18;32(2):326-332. doi: 10.1021/acs.chemrestox.8b00330. Epub 2019 Jan 11. PubMed PMID: 30596229; PubMed Central PMCID: PMC6469359.

select

Ozpiskin OM, Zhang L, Li JJ. Immune targets in the tumor microenvironment treated by radiotherapy. Theranostics. 2019;9(5):1215-1231. doi: 10.7150/thno.32648. eCollection 2019. Review. PubMed PMID: 30867826; PubMed Central PMCID: PMC6401500.

select

Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS. Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer. Nano Lett. 2018 Nov 14;18(11):7092-7103. doi: 10.1021/acs.nanolett.8b03096. Epub 2018 Oct 26. PubMed PMID: 30339018; PubMed Central PMCID: PMC6501589.

select

Navas-Moreno M, Mehrpouyan M, Chernenko T, Candas D, Fan M, Li JJ, Yan M, Chan JW. Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. Sci Rep. 2017 Jun 30;7(1):4471. doi: 10.1038/s41598-017-04066-0. PubMed PMID: 28667313; PubMed Central PMCID: PMC5493633.

select

Miller RC, Murley JS, Rademaker AW, Woloschak GE, Li JJ, Weichselbaum RR, Grdina DJ. Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity. Free Radic Biol Med. 2016 Oct;99:110-119. doi: 10.1016/j.freeradbiomed.2016.07.009. Epub 2016 Jul 15. PubMed PMID: 27427516; PubMed Central PMCID: PMC6764831.

select

Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes. Cancer Lett. 2016 Aug 10;378(2):69-79. doi: 10.1016/j.canlet.2016.05.004. Epub 2016 May 6. PubMed PMID: 27164560; PubMed Central PMCID: PMC7505026.

select

Yan Y, Li Z, Xu X, Chen C, Wei W, Fan M, Chen X, Li JJ, Wang Y, Huang J. All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy. BMC Complement Altern Med. 2016 Mar 31;16:113. doi: 10.1186/s12906-016-1088-y. PubMed PMID: 27036550; PubMed Central PMCID: PMC4815257.

select

Candas D, Qin L, Fan M, Li JJ. Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1. J Vis Exp. 2016 Feb 25;(108):53417. doi: 10.3791/53417. PubMed PMID: 26967001; PubMed Central PMCID: PMC4828183.

select

Qin L, Fan M, Candas D, Jiang G, Papadopoulos S, Tian L, Woloschak G, Grdina DJ, Li JJ. CDK1 Enhances Mitochondrial Bioenergetics for Radiation-Induced DNA Repair. Cell Rep. 2015 Dec 15;13(10):2056-63. doi: 10.1016/j.celrep.2015.11.015. Epub 2015 Dec 6. PubMed PMID: 26670043; PubMed Central PMCID: PMC4684969.

select

Sun W, Wei X, Niu A, Ma X, Li JJ, Gao D. Enhanced anti-colon cancer immune responses with modified eEF2-derived peptides. Cancer Lett. 2015 Dec 1;369(1):112-23. doi: 10.1016/j.canlet.2015.08.002. Epub 2015 Aug 21. PubMed PMID: 26304717.

select

Nantajit D, Lin D, Li JJ. The network of epithelial-mesenchymal transition: potential new targets for tumor resistance. J Cancer Res Clin Oncol. 2015 Oct;141(10):1697-713. doi: 10.1007/s00432-014-1840-y. Epub 2014 Oct 1. Review. PubMed PMID: 25270087; PubMed Central PMCID: PMC4382462.

select

Candas D, Li JJ. MKP1 mediates resistance to therapy in HER2-positive breast tumors. Mol Cell Oncol. 2015 Oct-Dec;2(4):e997518. doi: 10.1080/23723556.2014.997518. eCollection 2015 Oct-Dec. PubMed PMID: 27308517; PubMed Central PMCID: PMC4905363.

select

Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, Zou JX, Zhang T, Juma S, Jin C, Li RF, Perks J, Sun LQ, Vaughan AT, Hai CX, Gius DR, Li JJ. CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015 Sep;14(9):2090-102. doi: 10.1158/1535-7163.MCT-15-0017. Epub 2015 Jul 3. PubMed PMID: 26141949; PubMed Central PMCID: PMC4560959.

select

Cui Y, Qin L, Wu J, Qu X, Hou C, Sun W, Li S, Vaughan AT, Li JJ, Liu J. SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells. PLoS One. 2015;10(6):e0129834. doi: 10.1371/journal.pone.0129834. eCollection 2015. PubMed PMID: 26121691; PubMed Central PMCID: PMC4487898.

select

Jin C, Qin L, Shi Y, Candas D, Fan M, Lu CL, Vaughan AT, Shen R, Wu LS, Liu R, Li RF, Murley JS, Woloschak G, Grdina DJ, Li JJ. CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection. Free Radic Biol Med. 2015 Apr;81:77-87. doi: 10.1016/j.freeradbiomed.2014.12.026. Epub 2015 Jan 8. PubMed PMID: 25578653; PubMed Central PMCID: PMC4359946.

select

Grdina DJ, Murley JS, Miller RC, Woloschak GE, Li JJ. NFκB and Survivin-Mediated Radio-Adaptive Response. Radiat Res. 2015 Apr;183(4):391-7. doi: 10.1667/RR14002.1. Epub 2015 Mar 12. PubMed PMID: 25763931.

select

Lu CL, Qin L, Liu HC, Candas D, Fan M, Li JJ. Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect. PLoS One. 2015;10(3):e0121046. doi: 10.1371/journal.pone.0121046. eCollection 2015. PubMed PMID: 25807077; PubMed Central PMCID: PMC4373728.

select

Perks JR, Lucero S, Monjazeb AM, Li JJ. Anthropomorphic Phantoms for Confirmation of Linear Accelerator-Based Small Animal Irradiation. Cureus. 2015 Mar;7(3):e254. doi: 10.7759/cureus.254. eCollection 2015 Mar. PubMed PMID: 26180678; PubMed Central PMCID: PMC4494576.

select

Guo L, Xiao Y, Fan M, Li JJ, Wang Y. Profiling global kinome signatures of the radioresistant MCF-7/C6 breast cancer cells using MRM-based targeted proteomics. J Proteome Res. 2015 Jan 2;14(1):193-201. doi: 10.1021/pr500919w. Epub 2014 Nov 4. PubMed PMID: 25341124; PubMed Central PMCID: PMC4286165.

select

Candas D, Lu CL, Fan M, Chuang FY, Sweeney C, Borowsky AD, Li JJ. Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells. Cancer Res. 2014 Dec 15;74(24):7498-509. doi: 10.1158/0008-5472.CAN-14-0844. Epub 2014 Nov 6. PubMed PMID: 25377473; PubMed Central PMCID: PMC4267894.

select

Geng SQ, Alexandrou AT, Li JJ. Breast cancer stem cells: Multiple capacities in tumor metastasis. Cancer Lett. 2014 Jul 10;349(1):1-7. doi: 10.1016/j.canlet.2014.03.036. Epub 2014 Apr 12. Review. PubMed PMID: 24727284; PubMed Central PMCID: PMC4177877.

select

Wang Y, Li W, Patel SS, Cong J, Zhang N, Sabbatino F, Liu X, Qi Y, Huang P, Lee H, Taghian A, Li JJ, DeLeo AB, Ferrone S, Epperly MW, Ferrone CR, Ly A, Brachtel EF, Wang X. Blocking the formation of radiation-induced breast cancer stem cells. Oncotarget. 2014 Jun 15;5(11):3743-55. doi: 10.18632/oncotarget.1992. PubMed PMID: 25003837; PubMed Central PMCID: PMC4116517.

select

Wang Z, Fan M, Candas D, Zhang TQ, Qin L, Eldridge A, Wachsmann-Hogiu S, Ahmed KM, Chromy BA, Nantajit D, Duru N, He F, Chen M, Finkel T, Weinstein LS, Li JJ. Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression. Dev Cell. 2014 Apr 28;29(2):217-32. doi: 10.1016/j.devcel.2014.03.012. Epub 2014 Apr 17. PubMed PMID: 24746669; PubMed Central PMCID: PMC4156313.

select

Gao D, Li C, Xie X, Zhao P, Wei X, Sun W, Liu HC, Alexandrou AT, Jones J, Zhao R, Li JJ. Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients. PLoS One. 2014;9(4):e93886. doi: 10.1371/journal.pone.0093886. eCollection 2014. PubMed PMID: 24699863; PubMed Central PMCID: PMC3974849.

select

Zou JX, Duan Z, Wang J, Sokolov A, Xu J, Chen CZ, Li JJ, Chen HW. Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance. Mol Cancer Res. 2014 Apr;12(4):539-49. doi: 10.1158/1541-7786.MCR-13-0459. Epub 2014 Jan 3. PubMed PMID: 24391143; PubMed Central PMCID: PMC4139106.

select

Candas D, Li JJ. MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx. Antioxid Redox Signal. 2014 Apr 1;20(10):1599-617. doi: 10.1089/ars.2013.5305. Epub 2013 Jun 8. Review. PubMed PMID: 23581847; PubMed Central PMCID: PMC3942709.

select

Alexandrou AT, Li JJ. Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response. Antioxid Redox Signal. 2014 Mar 20;20(9):1463-80. doi: 10.1089/ars.2013.5684. Epub 2014 Feb 14. Review. PubMed PMID: 24180340; PubMed Central PMCID: PMC3936506.

select

Duru N, Candas D, Jiang G, Li JJ. Breast cancer adaptive resistance: HER2 and cancer stem cell repopulation in a heterogeneous tumor society. J Cancer Res Clin Oncol. 2014 Jan;140(1):1-14. doi: 10.1007/s00432-013-1494-1. Epub 2013 Aug 30. Review. PubMed PMID: 23990015; PubMed Central PMCID: PMC3889683.

select

Bourguignon LY, Shiina M, Li JJ. Hyaluronan-CD44 interaction promotes oncogenic signaling, microRNA functions, chemoresistance, and radiation resistance in cancer stem cells leading to tumor progression. Adv Cancer Res. 2014;123:255-75. doi: 10.1016/B978-0-12-800092-2.00010-1. Review. PubMed PMID: 25081533; PubMed Central PMCID: PMC6759082.

select

Diaz AJ, Tamae D, Yen Y, Li J, Wang T. Enhanced radiation response in radioresistant MCF-7 cells by targeting peroxiredoxin II. Breast Cancer (Dove Med Press). 2013;5:87-101. doi: 10.2147/BCTT.S51378. eCollection 2013. PubMed PMID: 24648762; PubMed Central PMCID: PMC3929248.

select

Ding NH, Li JJ, Sun LQ. Molecular mechanisms and treatment of radiation-induced lung fibrosis. Curr Drug Targets. 2013 Oct;14(11):1347-56. doi: 10.2174/13894501113149990198. Review. PubMed PMID: 23909719; PubMed Central PMCID: PMC4156316.

select

Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Li JJ, Woloschak GE, Weichselbaum RR. A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15;73(14):4418-28. doi: 10.1158/0008-5472.CAN-12-4640. Epub 2013 May 7. PubMed PMID: 23651635; PubMed Central PMCID: PMC3721325.

select

Liu W, Haley B, Kwasny MJ, Li JJ, Grdina DJ, Paunesku T, Woloschak GE. Comparing radiation toxicities across species: an examination of radiation effects in Mus musculus and Peromyscus leucopus. Int J Radiat Biol. 2013 Jun;89(6):391-400. doi: 10.3109/09553002.2013.767994. Epub 2013 Mar 4. PubMed PMID: 23362954.

select

Candas D, Fan M, Nantajit D, Vaughan AT, Murley JS, Woloschak GE, Grdina DJ, Li JJ. CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress. J Mol Cell Biol. 2013 Jun;5(3):166-75. doi: 10.1093/jmcb/mjs062. Epub 2012 Dec 12. PubMed PMID: 23243068; PubMed Central PMCID: PMC3656610.

select

Menaa C, Fan M, Lu H, Alexandrou A, Juma J, Perks J, Li JJ. The dynamic change of CD47 expression promotes tumor burden, metastases and resistance of breast cancer cells to radiotherapy. Cancer Research. 2013 April; 73:4963. doi: 10.1158/1538-7445.AM2013-4963.

select

Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Thirman MJ, Li JJ, Woloschak GE, Weichselbaum RR. A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb;179(2):115-24. doi: 10.1667/RR3126.2. Epub 2012 Dec 13. PubMed PMID: 23237540; PubMed Central PMCID: PMC3594688.

select

Menaa C, Li JJ. The role of radiotherapy-resistant stem cells in breast cancer recurrence. Breast Cancer Manag. 2013;2(2):89-92. doi: 10.2217/bmt.13.5. PubMed PMID: 25598844; PubMed Central PMCID: PMC4295787.