My Bibliography

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Lee D, Shin J, Ahnn J. A Screen for Genetic Loci on the X Chromosome Required for Body-Wall Muscle Development during Embryogenesis in Caenorhabditis elegans. Korean J. Biol. Sci.. 1997; 1:355-361.

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Shin J, Kim S, Ahnn J. Analysis of Flectin-like Gene Expression on Caenorhabditis elegans Using Germ-line Transformation. Korean J. Biol. Sci.. 1998; 3:377-382.

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Cho J, Oh Y, Park K, Yun J, Choi K, Shin J, Kim D, Park W, T H, H K, Mayon E, Bandyopadhyay J, Ahnn J. Calsequestrin, a calcium sequestering protein localized at the sarcoplasmic reticulum, is not essential for body-wall muscle function in Caenorhabditis elegans. J. Cell Sci.. 2000; 113:3947-3958.

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Shin JY, Fang ZH, Yu ZX, Wang CE, Li SH, Li XJ. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J Cell Biol. 2005 Dec 19;171(6):1001-12. doi: 10.1083/jcb.200508072. PubMed PMID: 16365166; PubMed Central PMCID: PMC2171327.

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Rong J, McGuire JR, Fang ZH, Sheng G, Shin JY, Li SH, Li XJ. Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth. J Neurosci. 2006 May 31;26(22):6019-30. doi: 10.1523/JNEUROSCI.1251-06.2006. PubMed PMID: 16738245; PubMed Central PMCID: PMC6675209.

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Cornett J, Smith L, Friedman M, Shin JY, Li XJ, Li SH. Context-dependent dysregulation of transcription by mutant huntingtin. J Biol Chem. 2006 Nov 24;281(47):36198-204. doi: 10.1074/jbc.M607839200. Epub 2006 Sep 29. PubMed PMID: 17012230.

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Xu Y, Toh KL, Jones CR, Shin JY, Fu YH, Ptácek LJ. Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell. 2007 Jan 12;128(1):59-70. doi: 10.1016/j.cell.2006.11.043. PubMed PMID: 17218255; PubMed Central PMCID: PMC1828903.

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Shin D, Shin JY, McManus MT, Ptácek LJ, Fu YH. Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol. 2009 Dec;66(6):843-57. doi: 10.1002/ana.21927. PubMed PMID: 20035504; PubMed Central PMCID: PMC2885004.

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Bradford J, Shin JY, Roberts M, Wang CE, Li XJ, Li S. Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22480-5. doi: 10.1073/pnas.0911503106. Epub 2009 Dec 11. PubMed PMID: 20018729; PubMed Central PMCID: PMC2799722.

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Bradford J, Shin JY, Roberts M, Wang CE, Sheng G, Li S, Li XJ. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. J Biol Chem. 2010 Apr 2;285(14):10653-61. doi: 10.1074/jbc.M109.083287. Epub 2010 Feb 9. PubMed PMID: 20145253; PubMed Central PMCID: PMC2856273.

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Shin JY, Méndez-López I, Wang Y, Hays AP, Tanji K, Lefkowitch JH, Schulze PC, Worman HJ, Dauer WT. Lamina-associated polypeptide-1 interacts with the muscular dystrophy protein emerin and is essential for skeletal muscle maintenance. Dev Cell. 2013 Sep 30;26(6):591-603. doi: 10.1016/j.devcel.2013.08.012. Epub 2013 Sep 19. PubMed PMID: 24055652; PubMed Central PMCID: PMC3798056.

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Shin JY, Dauer WT, Worman HJ. Lamina-associated polypeptide 1: protein interactions and tissue-selective functions. Semin Cell Dev Biol. 2014 May;29:164-8. doi: 10.1016/j.semcdb.2014.01.010. Epub 2014 Feb 5. Review. PubMed PMID: 24508913; PubMed Central PMCID: PMC4040325.

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Shin JY, Le Dour C, Sera F, Iwata S, Homma S, Joseph LC, Morrow JP, Dauer WT, Worman HJ. Depletion of lamina-associated polypeptide 1 from cardiomyocytes causes cardiac dysfunction in mice. Nucleus. 2014 May-Jun;5(3):260-459. doi: 10.4161/nucl.29227. Epub 2014 May 23. PubMed PMID: 24859316; PubMed Central PMCID: PMC4133221.

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Wang Y, Lichter-Konecki U, Anyane-Yeboa K, Shaw JE, Lu JT, Östlund C, Shin JY, Clark LN, Gundersen GG, Nagy PL, Worman HJ. A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder. J Cell Sci. 2016 May 15;129(10):1975-80. doi: 10.1242/jcs.187302. Epub 2016 Mar 31. PubMed PMID: 27034136; PubMed Central PMCID: PMC4878994.

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Shin JY, Méndez-López I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ. Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth. Hum Mol Genet. 2017 Jan 1;26(1):65-78. doi: 10.1093/hmg/ddw368. PubMed PMID: 27798115; PubMed Central PMCID: PMC6075563.

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Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ. Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. Bioorg Med Chem. 2017 Feb 1;25(3):1004-1013. doi: 10.1016/j.bmc.2016.12.014. Epub 2016 Dec 9. PubMed PMID: 28011205; PubMed Central PMCID: PMC5291759.

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Wang Y, Shin JY, Nakanishi K, Homma S, Kim GJ, Tanji K, Joseph LC, Morrow JP, Stewart CL, Dauer WT, Worman HJ. Postnatal development of mice with combined genetic depletions of lamin A/C, emerin and lamina-associated polypeptide 1. Hum Mol Genet. 2019 Aug 1;28(15):2486-2500. doi: 10.1093/hmg/ddz082. PubMed PMID: 31009944; PubMed Central PMCID: PMC7590221.

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Shin JY, Hernandez-Ono A, Fedotova T, Östlund C, Lee MJ, Gibeley SB, Liang CC, Dauer WT, Ginsberg HN, Worman HJ. Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis. J Clin Invest. 2019 Aug 13;129(11):4885-4900. doi: 10.1172/JCI129769. PubMed PMID: 31408437; PubMed Central PMCID: PMC6819140.

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Östlund C, Hernandez-Ono A, Shin JY. The Nuclear Envelope in Lipid Metabolism and Pathogenesis of NAFLD. Biology (Basel). 2020 Oct 15;9(10). doi: 10.3390/biology9100338. Review. PubMed PMID: 33076344; PubMed Central PMCID: PMC7602593.

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Cossins J, Webster R, Maxwell S, Rodríguez Cruz PM, Knight R, Llewelyn JG, Shin JY, Palace J, Beeson D. Congenital myasthenic syndrome due to a TOR1AIP1 mutation: a new disease pathway for impaired synaptic transmission. Brain Commun. 2020;2(2):fcaa174. doi: 10.1093/braincomms/fcaa174. eCollection 2020. PubMed PMID: 33215087; PubMed Central PMCID: PMC7660151.

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Kronenberg-Tenga R, Tatli M, Eibauer M, Wu W, Shin JY, Bonne G, Worman HJ, Medalia O. A lamin A/C variant causing striated muscle disease provides insights into filament organization. J Cell Sci. 2021 Mar 22;134(6). doi: 10.1242/jcs.256156. PubMed PMID: 33536248; PubMed Central PMCID: PMC8015223.

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Shin JY, Worman HJ. Molecular Pathology of Laminopathies. Annu Rev Pathol. 2022 Jan 24;17:159-180. doi: 10.1146/annurev-pathol-042220-034240. Epub 2021 Oct 21. Review. PubMed PMID: 34672689; PubMed Central PMCID: PMC8881990.

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Östlund C, Hernandez-Ono A, Turk SJ, Dauer WT, Ginsberg HN, Worman HJ, Shin JY. Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets. J Lipid Res. 2022 Oct;63(10):100277. doi: 10.1016/j.jlr.2022.100277. Epub 2022 Sep 10. PubMed PMID: 36100089; PubMed Central PMCID: PMC9587410.