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Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger HL, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph DJ, Tobias JS. Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial. BMJ. 2020 Aug 19;370:m2836. doi: 10.1136/bmj.m2836. PubMed PMID: 32816842; PubMed Central PMCID: PMC7500441.
Vaidya JS, Bulsara M, Baum M. Targeted Intraoperative Radiotherapy for Early Breast Cancer-Reply. JAMA Oncol. 2020 Aug 13;. doi: 10.1001/jamaoncol.2020.2730. [Epub ahead of print] PubMed PMID: 32789486.
Pal UM, Gk AV, Gogoi G, Rila S, Shroff S, Am G, Borah P, Varma M, Kurpad V, Baruah D, Vaidya JS, Pandya HJ. Towards a Portable Platform Integrated With Multispectral Noncontact Probes for Delineating Normal and Breast Cancer Tissue Based on Near-Infrared Spectroscopy. IEEE Trans Biomed Circuits Syst. 2020 Aug;14(4):879-888. doi: 10.1109/TBCAS.2020.3005971. Epub 2020 Jun 30. PubMed PMID: 32746350.
Vaidya JS, Bulsara M, Saunders C, Flyger H, Tobias JS, Corica T, Massarut S, Wenz F, Pigorsch S, Alvarado M, Douek M, Eiermann W, Brew-Graves C, Williams N, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Baum M, Joseph D. Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival: Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer. JAMA Oncol. 2020 Jul 1;6(7):e200249. doi: 10.1001/jamaoncol.2020.0249. Epub 2020 Jul 9. PubMed PMID: 32239210; PubMed Central PMCID: PMC7348682.
Retsky M, Demicheli R, Hrushesky W, James T, Rogers R, Baum M, Vaidya JS, Erhabor O, Forget P. Breast cancer and the black swan. Ecancermedicalscience. 2020;14:1050. doi: 10.3332/ecancer.2020.1050. eCollection 2020. Review. PubMed PMID: 32565903; PubMed Central PMCID: PMC7289621.
Simcock R, Thomas TV, Estes C, Filippi AR, Katz MA, Pereira IJ, Saeed H. COVID-19: Global radiation oncology's targeted response for pandemic preparedness. Clin Transl Radiat Oncol. 2020 May;22:55-68. doi: 10.1016/j.ctro.2020.03.009. eCollection 2020 May. PubMed PMID: 32274425; PubMed Central PMCID: PMC7102593.
Pal UM, Saxena M, Vishnu G, Parsana D, Sarvani B, Varma M, Jayachandra M, Kurpad V, Baruch D, Gogoi G, Vaidya JS, Pandya HJ. Optical spectroscopy-based imaging techniques for the diagnosis of breast cancer: A novel approach. Applied Spectroscopy Reviews. 2020 April; doi: 10.1080/05704928.2020.1749651.
Davis CR, Than PA, Khong SML, Rodrigues M, Findlay MW, Navarrete DJ, Ghali S, Vaidya JS, Gurtner GC. Therapeutic Breast Reconstruction Using Gene Therapy-Delivered IFNγ Immunotherapy. Mol Cancer Ther. 2020 Feb;19(2):697-705. doi: 10.1158/1535-7163.MCT-19-0315. Epub 2019 Oct 28. PubMed PMID: 31658961; NIHMSID:NIHMS1541590.
Cuzick J, Sestak I, Forbes JF, Dowsett M, Cawthorn S, Mansel RE, Loibl S, Bonanni B, Evans DG, Howell A. Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial. Lancet. 2020 Jan 11;395(10218):117-122. doi: 10.1016/S0140-6736(19)32955-1. Epub 2019 Dec 12. PubMed PMID: 31839281; PubMed Central PMCID: PMC6961114.
Kolberg HC, Uhl V, Massarut S, Holmes D, Kolberg-Liedtke C, Kelly EW, Lövey G, Vaidya JS. Targeted Intraoperative Radiotherapy During Breast-conserving Surgery for Breast Cancer in Patients After Implant Augmentation. Anticancer Res. 2019 Aug;39(8):4215-4218. doi: 10.21873/anticanres.13582. PubMed PMID: 31366508.
Earl HM, Hiller L, Vallier AL, Loi S, McAdam K, Hughes-Davies L, Harnett AN, Ah-See ML, Simcock R, Rea D, Raj S, Woodings P, Harries M, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mansi J, Gounaris I, Mahler-Araujo B, Provenzano E, Chhabra A, Abraham JE, Caldas C, Hall PS, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA. 6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial. Lancet. 2019 Jun 29;393(10191):2599-2612. doi: 10.1016/S0140-6736(19)30650-6. Epub 2019 Jun 6. PubMed PMID: 31178152; PubMed Central PMCID: PMC6615016.
Thorneloe RJ, Horne R, Side L, Wolf MS, Smith SG. Beliefs About Medication and Uptake of Preventive Therapy in Women at Increased Risk of Breast Cancer: Results From a Multicenter Prospective Study. Clin Breast Cancer. 2019 Feb;19(1):e116-e126. doi: 10.1016/j.clbc.2018.10.008. Epub 2018 Dec 3. PubMed PMID: 30518498; PubMed Central PMCID: PMC6395889.
Cutress RI, McIntosh SA, Potter S, Goyal A, Kirwan CC, Harvey J, Francis A, Carmichael AR, Vidya R, Vaidya JS, Fairbrother P, Benson JR, Reed MWR. Opportunities and priorities for breast surgical research. Lancet Oncol. 2018 Oct;19(10):e521-e533. doi: 10.1016/S1470-2045(18)30511-4. Epub 2018 Oct 1. Review. PubMed PMID: 30303126.
Winters ZE, Horsnell J, Elvers KT, Maxwell AJ, Jones LJ, Shaaban AM, Schmid P, Williams NR, Beswick A, Greenwood R, Ingram JC, Saunders C, Vaidya JS, Esserman L, Jatoi I, Brunt AM. Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers. BJS Open. 2018 Aug;2(4):162-174. doi: 10.1002/bjs5.53. eCollection 2018 Aug. Review. PubMed PMID: 30079385; PubMed Central PMCID: PMC6069349.
Kolberg H, Uhl V, Massarut S, Liedtke C, Lovey G, Vaidya JS. Targeted intraoperative radiotherapy (TARGIT) during breast conserving surgery for early breast cancer in patient after breast augmentation with implants- a case series (n=8). Senologie - Zeitschrift für Mammadiagnostik und -therapie. 2018 May; 15(2):e27. doi: 10.1055/s-0038-1651746.
Corica T, Nowak AK, Saunders CM, Bulsara MK, Taylor M, Williams NR, Keshtgar M, Joseph DJ, Vaidya JS. Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial. Radiat Oncol. 2018 Apr 13;13(1):68. doi: 10.1186/s13014-018-0998-x. PubMed PMID: 29653541; PubMed Central PMCID: PMC5899392.
Kolberg H, Uhl V, Massarut S, Lidtke C, Lovy G, Vaidya JS. Targeted intraoperative radiotherapy (TARGIT) during breast conserving surgery for early breast cancer in patients after breast augmentation with implants - a case series. Oncology Research and Treatment. 2018 March; 41(Suppl 1):30. doi: 10.1159/000487109.
Vaidya JS, Wenz F, Tobias JS. Trial supports targeted radiotherapy for early breast cancer but protocol still requires 3 weeks of daily therapy. BMJ Evid Based Med. 2018 Feb;23(1):38-39. doi: 10.1136/ebmed-2017-110849. Review. PubMed PMID: 29367327.
Vaidya JS, Massarut S, Vaidya HJ, Alexander EC, Richards T, Caris JA, Sirohi B, Tobias JS. Rethinking neoadjuvant chemotherapy for breast cancer. BMJ. 2018 Jan 11;360:j5913. doi: 10.1136/bmj.j5913. PubMed PMID: 29326104.
Vaidya JS, Bulsara M, Wenz F, Tobias JS, Joseph D, Baum M. Targeted radiotherapy for early breast cancer. Lancet. 2018 Jan 6;391(10115):26-27. doi: 10.1016/S0140-6736(17)33316-0. PubMed PMID: 29323648.
Vaidya JS, Tobias JS. Targeted Intraoperative Radiotherapy Tumour Bed Boost during Breast-Conserving Surgery after Neoadjuvant Chemotherapy. Breast Care (Basel). 2017 Oct;12(5):314-316. doi: 10.1159/000479726. Epub 2017 Oct 27. PubMed PMID: 29234251; PubMed Central PMCID: PMC5704699.
Kolberg HC, Lövey G, Akpolat-Basci L, Stephanou M, Fasching P, Untch M, Hoffmann O, Bulsara M, Vaidya J, Liedtke C. Targeted Intraoperative Radiotherapy Tumour Bed Boost during Breast-Conserving Surgery after Neoadjuvant Chemotherapy - a Subgroup Analysis of Hormone Receptor-Positive HER2-Negative Breast Cancer. Breast Care (Basel). 2017 Oct;12(5):318-323. doi: 10.1159/000479424. Epub 2017 Sep 21. PubMed PMID: 29234252; PubMed Central PMCID: PMC5704703.
Vaidya A, Vaidya P, Both B, Brew-Graves C, Bulsara M, Vaidya JS. Health economics of targeted intraoperative radiotherapy (TARGIT-IORT) for early breast cancer: a cost-effectiveness analysis in the United Kingdom. BMJ Open. 2017 Aug 17;7(8):e014944. doi: 10.1136/bmjopen-2016-014944. PubMed PMID: 28819067; PubMed Central PMCID: PMC5724101.
Small W Jr, Thomas TO, Alvarado M, Baum M, Bulsara M, Diaz R, Donnelly E, Feldman S, Grobmyer S, Hoefer R, Joseph D, Kang S, Laronga C, McKee A, Rosen B, Tobias J, Uhl V, Vaidya JS, Wenz F, Holmes D. Commentary on "Accelerated partial breast irradiation consensus statement: Update of an ASTRO Evidence-Based Consensus Statement". Pract Radiat Oncol. 2017 May - Jun;7(3):e159-e163. doi: 10.1016/j.prro.2017.01.016. Epub 2017 Feb 9. PubMed PMID: 28363492.
Kolberg HC, Loevey G, Akpolat-Basci L, Stephanou M, Fasching PA, Untch M, Liedtke C, Bulsara M, Vaidya JS. Targeted intraoperative radiotherapy tumour bed boost during breast-conserving surgery after neoadjuvant chemotherapy. Strahlenther Onkol. 2017 Jan;193(1):62-69. doi: 10.1007/s00066-016-1072-y. Epub 2016 Nov 17. PubMed PMID: 27858093.
Kolberg HC, Loevey G, Akpolat-Basci L, Stephanou M, Fasching PA, Untch M, Bulsara M, Vaidya JS, Liedtke C. Targeted Intraoperative Radiotherapy Tumour Bed Boost During Breast Conserving Surgery after Neoadjuvant Chemotherapy in HER2 Positive and Triple Negative Breast Cancer. Rev Recent Clin Trials. 2017;12(2):93-100. doi: 10.2174/1574887112666170201142458. PubMed PMID: 28155607.
Vaidya JS. The Systemic Effects of Local Treatments (Surgery and Radiotherapy) of Breast Cancer . In: Perioperative Inflammation as Triggering Origin of Metastasis Development. 1st ed. Retsky M, Demicheli R, editors. Boston: Springer Nature; 2017. Chapter 11; p.227-236.
Gellert P, Segal CV, Gao Q, López-Knowles E, Martin LA, Dodson A, Li T, Miller CA, Lu C, Mardis ER, Gillman A, Morden J, Graf M, Sidhu K, Evans A, Shere M, Holcombe C, McIntosh SA, Bundred N, Skene A, Maxwell W, Robertson J, Bliss JM, Smith I, Dowsett M. Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation. Nat Commun. 2016 Nov 9;7:13294. doi: 10.1038/ncomms13294. PubMed PMID: 27827358; PubMed Central PMCID: PMC5105193.
Vaidya JS, Bulsara M, Wenz F, Coombs N, Singer J, Ebbs S, Massarut S, Saunders C, Douek M, Williams N, Joseph D, Tobias JS, Baum M. In Reply to Park et al. Int J Radiat Oncol Biol Phys. 2016 Nov 1;96(3):707-8. doi: 10.1016/j.ijrobp.2016.06.2461. PubMed PMID: 27681769.
Watts G. Umberto Veronesi. The Lancet. 2016 November; 388(10060):2600-. doi: 10.1016/S0140-6736(16)32230-9.
Vaidya JS, Bulsara M, Wenz F, Coombs N, Singer J, Ebbs S, Massarut S, Saunders C, Douek M, Williams NR, Joseph D, Tobias JS, Baum M. Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials. Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):259-265. doi: 10.1016/j.ijrobp.2016.05.008. Epub 2016 May 13. Review. PubMed PMID: 27478165.
Fabris L, Berton S, Citron F, D'Andrea S, Segatto I, Nicoloso MS, Massarut S, Armenia J, Zafarana G, Rossi S, Ivan C, Perin T, Vaidya JS, Avanzo M, Roncadin M, Schiappacassi M, Bristow RG, Calin G, Baldassarre G, Belletti B. Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway. Oncogene. 2016 Sep 15;35(37):4914-26. doi: 10.1038/onc.2016.23. Epub 2016 Feb 15. PubMed PMID: 26876200; PubMed Central PMCID: PMC5028421.
Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Saunders C, Brew-Graves C, Potyka I, Morris S, Vaidya HJ, Williams NR, Baum M. An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial). Health Technol Assess. 2016 Sep;20(73):1-188. doi: 10.3310/hta20730. PubMed PMID: 27689969; PubMed Central PMCID: PMC5056335.
Corica T, Nowak AK, Saunders CM, Bulsara M, Taylor M, Vaidya JS, Baum M, Joseph DJ. Cosmesis and Breast-Related Quality of Life Outcomes After Intraoperative Radiation Therapy for Early Breast Cancer: A Substudy of the TARGIT-A Trial. Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):55-64. doi: 10.1016/j.ijrobp.2016.04.024. Epub 2016 Apr 23. PubMed PMID: 27511847.
Coombs NJ, Coombs JM, Vaidya UJ, Singer J, Bulsara M, Tobias JS, Wenz F, Joseph DJ, Brown DA, Rainsbury R, Davidson T, Adamson DJ, Massarut S, Morgan D, Potyka I, Corica T, Falzon M, Williams N, Baum M, Vaidya JS. Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT. BMJ Open. 2016 May 9;6(5):e010703. doi: 10.1136/bmjopen-2015-010703. PubMed PMID: 27160842; PubMed Central PMCID: PMC4890331.
Vaidya JS, Bulsara M, Wenz F, Tobias JS, Joseph D, Baum M. Partial breast irradiation and the GEC-ESTRO trial. Lancet. 2016 Apr 23;387(10029):1717. doi: 10.1016/S0140-6736(16)30255-0. PubMed PMID: 27116272.
Forbes JF, Sestak I, Howell A, Bonanni B, Bundred N, Levy C, von Minckwitz G, Eiermann W, Neven P, Stierer M, Holcombe C, Coleman RE, Jones L, Ellis I, Cuzick J. Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial. Lancet. 2016 Feb 27;387(10021):866-73. doi: 10.1016/S0140-6736(15)01129-0. Epub 2015 Dec 11. PubMed PMID: 26686313; PubMed Central PMCID: PMC4769326.
Vaidya J, Tobias J, Wenz F, Massarut S, Bulsara M, Saunders C, Flyger H, Alvarado M, Eiermann W, Corica T, Joseph D, Baum M. A Risk-Adapted Approach to Breast Radiation Using Targeted Intraoperative Radiotherapy (TARGIT) . In: Short Course Breast Radiotherapy. Arthur D, Vicini F, Wazer D, Khan A, editors. Switzerland: Springer International Publishing; 2016. Chapter 21; p.327-346.
Pathmarajah P, Shah K, Taghipour K, Ramachandra S, Thorat MA, Chaudhry Z, Patkar V, Peters F, Connor T, Spurrell E, Tobias JS, Vaidya JS. Letrozole-induced necrotising leukocytoclastic small vessel vasculitis: First report of a case in the UK. Int J Surg Case Rep. 2015;16:77-80. doi: 10.1016/j.ijscr.2015.09.024. Epub 2015 Sep 26. PubMed PMID: 26432999; PubMed Central PMCID: PMC4643446.
Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M. In Regard to Hepel and Wazer. Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):953-954. doi: 10.1016/j.ijrobp.2015.05.038. Epub 2015 Jul 14. PubMed PMID: 26194663.
Wenz F, Sedlmayer F, Herskind C, Welzel G, Sperk E, Neumaier C, Gauter-Fleckenstein B, Vaidya JS, Sütterlin M. Accelerated Partial Breast Irradiation in Clinical Practice. Breast Care (Basel). 2015 Aug;10(4):247-52. doi: 10.1159/000437194. Epub 2015 Jul 15. Review. PubMed PMID: 26600760; PubMed Central PMCID: PMC4608660.
Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M. Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer. Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):491-7. doi: 10.1016/j.ijrobp.2015.03.022. Epub 2015 Apr 8. PubMed PMID: 26068479; PubMed Central PMCID: PMC4464618.
Morgan DA, Vaidya JS. Perspectives in breast cancer treatment: APBI and breast-conserving surgery. In regard to Moran et al and Smith et al. Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):967. doi: 10.1016/j.ijrobp.2014.07.044. Epub 2014 Oct 18. PubMed PMID: 25585788.
Vaidya A, Vaidya P, Both B, Brew-Graves C, Vaidya J. Cost Effectiveness Analysis of Targeted Intraoperative Radiotherapy Alone (TARGIT-A) in Early Breast Cancer Patients. Value Health. 2014 Nov;17(7):A640. doi: 10.1016/j.jval.2014.08.2306. Epub 2014 Oct 26. PubMed PMID: 27202288.
Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph D, Baum M. Radiotherapy for breast cancer, the TARGIT-A trial - Authors' reply. Lancet. 2014 May 17;383(9930):1719-20. doi: 10.1016/S0140-6736(14)60830-8. PubMed PMID: 24835613.
Cuzick J, Sestak I, Forbes JF, Dowsett M, Knox J, Cawthorn S, Saunders C, Roche N, Mansel RE, von Minckwitz G, Bonanni B, Palva T, Howell A. Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial. Lancet. 2014 Mar 22;383(9922):1041-8. doi: 10.1016/S0140-6736(13)62292-8. Epub 2013 Dec 12. PubMed PMID: 24333009.
Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C, Eiermann W, Metaxas M, Sperk E, Sütterlin M, Brown D, Esserman L, Roncadin M, Thompson A, Dewar JA, Holtveg HM, Pigorsch S, Falzon M, Harris E, Matthews A, Brew-Graves C, Potyka I, Corica T, Williams NR, Baum M. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. Lancet. 2014 Feb 15;383(9917):603-13. doi: 10.1016/S0140-6736(13)61950-9. Epub 2013 Nov 11. PubMed PMID: 24224997.
Vaidya JS, Bulsara M, Wenz F. Ischemic heart disease after breast cancer radiotherapy. N Engl J Med. 2013 Jun 27;368(26):2526-7. doi: 10.1056/NEJMc1304601. PubMed PMID: 23802528.
Vaidya J, Benson J, Tobias J. Targeted therapy for breast cancer: not all cancers will grow . In: Early Breast Cancer: From screening to multidisciplinary management. Benson J, Gui G, Tuttle T, editors. London: CRC Press, Taylor Francis Group; 2013///.
Vaidya JS. Should healthy populations be screened for breast cancer? A consultant surgeon's perspective. Qual Prim Care. 2013;21(3):189-92. PubMed PMID: 23968270.
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