SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies.
Viruses.
2024 Apr 28;16(5). doi: 10.3390/v16050697. Review. PubMed PMID:
38793580; PubMed Central PMCID:
PMC11125895.
An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV.
Emerg Microbes Infect.
2023 Dec;12(2):2275598. doi: 10.1080/22221751.2023.2275598. Epub 2023 Dec 11. PubMed PMID:
38078382; PubMed Central PMCID:
PMC10768737.
Clinical Performance Characteristics of the Swift Normalase Amplicon Panel for Sensitive Recovery of Severe Acute Respiratory Syndrome Coronavirus 2 Genomes.
J Mol Diagn.
2022 Sep;24(9):963-976. doi: 10.1016/j.jmoldx.2022.05.007. Epub 2022 Jul 18. PubMed PMID:
35863699; PubMed Central PMCID:
PMC9290336.
Predicting infectivity: comparing four PCR-based assays to detect culturable SARS-CoV-2 in clinical samples.
EMBO Mol Med.
2022 Feb 7;14(2):e15290. doi: 10.15252/emmm.202115290. Epub 2021 Dec 13. PubMed PMID:
34862752; PubMed Central PMCID:
PMC8819313.
An international, interlaboratory ring trial confirms the feasibility of an extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples.
PLoS One.
2022;17(1):e0261853. doi: 10.1371/journal.pone.0261853. eCollection 2022. PubMed PMID:
35025926; PubMed Central PMCID:
PMC8758094.
A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding. Version: 1. bioRxiv [preprint]. 2021 November. bioRxiv 2021.11.24.469793Available from: https://doi.org/10.1101/2021.11.24.469793.
SARS-CoV-2 triggers DNA damage response in Vero E6 cells.
Biochem Biophys Res Commun.
2021 Nov 19;579:141-145. doi: 10.1016/j.bbrc.2021.09.024. Epub 2021 Sep 15. PubMed PMID:
34600299; PubMed Central PMCID:
PMC8440005.
Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.
mBio.
2021 Aug 31;12(4):e0253120. doi: 10.1128/mBio.02531-20. Epub 2021 Jul 6. PubMed PMID:
34225492; PubMed Central PMCID:
PMC8406324.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Science.
2021 Aug 20;373(6557):931-936. doi: 10.1126/science.abg5827. Epub 2021 Jul 20. PubMed PMID:
34285133; PubMed Central PMCID:
PMC8809056.
Predicting Infectivity: Comparing Four PCR-based Assays to Detect Culturable SARS-CoV-2 in Clinical Samples.
medRxiv https://doi.org/10.1101/2021.07.14.21260544. 2021 July.
Laboratory Worker Self-Contamination with Noninfectious SARS-CoV-2 DNA Can Result in False-Positive Reverse Transcriptase PCR-Based Surveillance Testing.
J Clin Microbiol.
2021 Jun 18;59(7):e0072321. doi: 10.1128/JCM.00723-21. Epub 2021 Jun 18. PubMed PMID:
33952597; PubMed Central PMCID:
PMC8218757.
Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model.
Nat Commun.
2021 May 24;12(1):3054. doi: 10.1038/s41467-021-22930-6. PubMed PMID:
34031380; PubMed Central PMCID:
PMC8144425.
An international, interlaboratory ring trial confirms the feasibility of an open-source, extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples.
medRxiv.
2021 Apr 16;. doi: 10.1101/2021.04.10.21254091. PubMed PMID:
33880478; PubMed Central PMCID:
PMC8057246.
Stimulation of B Cell Immunity in Flavivirus-Naive Individuals by the Tetravalent Live Attenuated Dengue Vaccine TV003.
Cell Rep Med.
2020 Dec 22;1(9):100155. doi: 10.1016/j.xcrm.2020.100155. eCollection 2020 Dec 22. PubMed PMID:
33377126; PubMed Central PMCID:
PMC7762770.
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.
Cell.
2020 Nov 25;183(5):1325-1339.e21. doi: 10.1016/j.cell.2020.10.004. Epub 2020 Oct 8. PubMed PMID:
33080218; PubMed Central PMCID:
PMC7543886.
Kinetics and isotype assessment of antibodies targeting the spike protein receptor-binding domain of severe acute respiratory syndrome-coronavirus-2 in COVID-19 patients as a function of age, biological sex and disease severity.
Clin Transl Immunology.
2020;9(10):e1189. doi: 10.1002/cti2.1189. eCollection 2020. PubMed PMID:
33072323; PubMed Central PMCID:
PMC7541824.
Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step.
PLoS Biol.
2020 Oct;18(10):e3000896. doi: 10.1371/journal.pbio.3000896. eCollection 2020 Oct. PubMed PMID:
33006983; PubMed Central PMCID:
PMC7556528.
Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti-Andes orthohantavirus Neutralizing Antibodies in Patient Samples.
Front Cell Infect Microbiol.
2020;10:444. doi: 10.3389/fcimb.2020.00444. eCollection 2020. PubMed PMID:
33042854; PubMed Central PMCID:
PMC7527604.
Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro.
bioRxiv.
2020 Sep 1;. doi: 10.1101/2020.08.31.274639. PubMed PMID:
32908976; PubMed Central PMCID:
PMC7480023.
Kinetics and Isotype Assessment of Antibodies Targeting the Spike Protein Receptor Binding Domain of SARS-CoV-2 In COVID-19 Patients as a function of Age and Biological Sex.
medRxiv.
2020 Jul 16;. doi: 10.1101/2020.07.15.20154443. PubMed PMID:
32743592; PubMed Central PMCID:
PMC7386516.
Defective Interfering Particles of Negative-Strand RNA Viruses.
Trends Microbiol.
2020 Jul;28(7):554-565. doi: 10.1016/j.tim.2020.02.006. Epub 2020 Mar 26. Review. PubMed PMID:
32544442; PubMed Central PMCID:
PMC7298151.
'All In': a pragmatic framework for COVID-19 testing and action on a global scale.
EMBO Mol Med.
2020 Jun 8;12(6):e12634. doi: 10.15252/emmm.202012634. Epub 2020 May 27. PubMed PMID:
32375201; PubMed Central PMCID:
PMC7267598.
DIRECT RT-qPCR DETECTION OF SARS-CoV-2 RNA FROM PATIENT NASOPHARYNGEAL SWABS WITHOUT AN RNA EXTRACTION STEP.
bioRxiv.
2020 Apr 6;. doi: 10.1101/2020.03.20.001008. PubMed PMID:
32511328; PubMed Central PMCID:
PMC7239058.
Meeting report: Eleventh International Conference on Hantaviruses.
Antiviral Res.
2020 Apr;176:104733. doi: 10.1016/j.antiviral.2020.104733. Epub 2020 Feb 15. Review. PubMed PMID:
32068071.
Rapid Induction and Maintenance of Virus-Specific CD8(+) T(EMRA) and CD4(+) T(EM) Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans.
Front Immunol.
2020;11:479. doi: 10.3389/fimmu.2020.00479. eCollection 2020. PubMed PMID:
32265929; PubMed Central PMCID:
PMC7105617.
NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z.
PLoS Pathog.
2019 Nov;15(11):e1008100. doi: 10.1371/journal.ppat.1008100. eCollection 2019 Nov. PubMed PMID:
31710650; PubMed Central PMCID:
PMC6874086.
Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein.
Pathogens.
2018 Dec 9;7(4). doi: 10.3390/pathogens7040097. PubMed PMID:
30544850; PubMed Central PMCID:
PMC6313517.
Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A.
J Immunol.
2018 Oct 15;201(8):2377-2384. doi: 10.4049/jimmunol.1800503. Epub 2018 Aug 29. PubMed PMID:
30158125; PubMed Central PMCID:
PMC6179936.
Visualization of Arenavirus RNA Species in Individual Cells by Single-Molecule Fluorescence In Situ Hybridization Suggests a Model of Cyclical Infection and Clearance during Persistence.
J Virol.
2018 Jun 15;92(12). doi: 10.1128/JVI.02241-17. Print 2018 Jun 15. PubMed PMID:
29643234; PubMed Central PMCID:
PMC5974494.
A Proteomics Survey of Junín Virus Interactions with Human Proteins Reveals Host Factors Required for Arenavirus Replication.
J Virol.
2018 Feb 15;92(4). doi: 10.1128/JVI.01565-17. Print 2018 Feb 15. PubMed PMID:
29187543; PubMed Central PMCID:
PMC5790945.
The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein.
J Gen Virol.
2018 Feb;99(2):187-193. doi: 10.1099/jgv.0.001004. PubMed PMID:
29393022; PubMed Central PMCID:
PMC5884964.
Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle pre-assembly.
J Gen Virol.
2017 Oct;98(10):2454-2460. doi: 10.1099/jgv.0.000930. PubMed PMID:
28949905; PubMed Central PMCID:
PMC5725993.
A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR).
J Virol.
2017 Aug 1;91(15). doi: 10.1128/JVI.00763-17. Print 2017 Aug 1. PubMed PMID:
28539447; PubMed Central PMCID:
PMC5512243.
Patterns of Cellular Immunity Associated with Experimental Infection with rDEN2Δ30 (Tonga/74) Support Its Suitability as a Human Dengue Virus Challenge Strain.
J Virol.
2017 Apr 15;91(8). doi: 10.1128/JVI.02133-16. Print 2017 Apr 15. PubMed PMID:
28148797; PubMed Central PMCID:
PMC5375662.
A novel phosphoserine motif in the LCMV matrix protein Z regulates the release of infectious virus and defective interfering particles.
J Gen Virol.
2016 Sep;97(9):2084-2089. doi: 10.1099/jgv.0.000550. Epub 2016 Jul 15. PubMed PMID:
27421645; PubMed Central PMCID:
PMC5756487.
The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles.
PLoS Pathog.
2016 Mar;12(3):e1005501. doi: 10.1371/journal.ppat.1005501. eCollection 2016 Mar. PubMed PMID:
27010636; PubMed Central PMCID:
PMC4806877.
Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment.
J Vis Exp.
2016 Mar 2;(109):e53682. doi: 10.3791/53682. PubMed PMID:
26966937; PubMed Central PMCID:
PMC4828211.
Strand-Specific Quantitative Reverse Transcription-Polymerase Chain Reaction Assay for Measurement of Arenavirus Genomic and Antigenomic RNAs.
PLoS One.
2015;10(5):e0120043. doi: 10.1371/journal.pone.0120043. eCollection 2015. PubMed PMID:
25978311; PubMed Central PMCID:
PMC4433285.
The intracellular cargo receptor ERGIC-53 is required for the production of infectious arenavirus, coronavirus, and filovirus particles.
Cell Host Microbe.
2013 Nov 13;14(5):522-34. doi: 10.1016/j.chom.2013.10.010. PubMed PMID:
24237698; PubMed Central PMCID:
PMC3999090.
CD8+ memory T cells appear exhausted within hours of acute virus infection.
J Immunol.
2013 Oct 15;191(8):4211-22. doi: 10.4049/jimmunol.1300920. Epub 2013 Sep 11. PubMed PMID:
24026080; PubMed Central PMCID:
PMC3795851.
Wild-type coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo.
Virology.
2012 Jul 20;429(1):74-90. doi: 10.1016/j.virol.2012.04.005. Epub 2012 May 1. PubMed PMID:
22551767; PubMed Central PMCID:
PMC3358485.
A multivalent vaccination strategy for the prevention of Old World arenavirus infection in humans.
J Virol.
2010 Oct;84(19):9947-56. doi: 10.1128/JVI.00672-10. Epub 2010 Jul 28. PubMed PMID:
20668086; PubMed Central PMCID:
PMC2937778.
Coverage of related pathogenic species by multivalent and cross-protective vaccine design: arenaviruses as a model system.
Microbiol Mol Biol Rev.
2010 Jun;74(2):157-70. doi: 10.1128/MMBR.00045-09. Review. PubMed PMID:
20508245; PubMed Central PMCID:
PMC2884409.
Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.
Immunome Res.
2010 May 17;6:4. doi: 10.1186/1745-7580-6-4. PubMed PMID:
20478058; PubMed Central PMCID:
PMC2880318.
Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus.
Hum Immunol.
2010 May;71(5):468-74. doi: 10.1016/j.humimm.2010.02.014. Epub 2010 Mar 10. PubMed PMID:
20156506; PubMed Central PMCID:
PMC2856764.
Universal influenza DNA vaccine encoding conserved CD4+ T cell epitopes protects against lethal viral challenge in HLA-DR transgenic mice.
Vaccine.
2010 Jan 8;28(3):664-72. doi: 10.1016/j.vaccine.2009.10.103. Epub 2009 Nov 4. PubMed PMID:
19895924; PubMed Central PMCID:
PMC3364000.
A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.
PLoS Pathog.
2009 Dec;5(12):e1000695. doi: 10.1371/journal.ppat.1000695. Epub 2009 Dec 18. PubMed PMID:
20019801; PubMed Central PMCID:
PMC2787016.
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes.
J Immunol.
2007 Jul 15;179(2):1058-67. doi: 10.4049/jimmunol.179.2.1058. PubMed PMID:
17617598.
The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus.
J Virol.
2007 May;81(10):4928-40. doi: 10.1128/JVI.02632-06. Epub 2007 Feb 28. PubMed PMID:
17329346; PubMed Central PMCID:
PMC1900207.
HLA-A2-restricted protection against lethal lymphocytic choriomeningitis.
J Virol.
2007 Mar;81(5):2307-17. doi: 10.1128/JVI.02063-06. Epub 2006 Dec 13. PubMed PMID:
17166907; PubMed Central PMCID:
PMC1865925.
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