Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.
Immunity.
2020 Dec 15;53(6):1272-1280.e5. doi: 10.1016/j.immuni.2020.10.023. Epub 2020 Nov 25. PubMed PMID:
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A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell.
2020 Nov 12;183(4):1058-1069.e19. doi: 10.1016/j.cell.2020.09.049. Epub 2020 Sep 23. PubMed PMID:
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A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.
J Exp Med.
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An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.
Cell Rep.
2020 Oct 20;33(3):108274. doi: 10.1016/j.celrep.2020.108274. Epub 2020 Sep 29. PubMed PMID:
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Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies.
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Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure.
Viruses.
2020 Sep 22;12(9). doi: 10.3390/v12091053. Review. PubMed PMID:
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A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
bioRxiv.
2020 Sep 21;. doi: 10.1101/2020.09.21.305441. PubMed PMID:
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A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv.
2020 Sep;6(38). doi: 10.1126/sciadv.abb1328. Print 2020 Sep. PubMed PMID:
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Self-assembling nanoparticles presenting receptor binding domain and stabilized spike as next-generation COVID-19 vaccines.
bioRxiv.
2020 Sep 14;. doi: 10.1101/2020.09.14.296715. PubMed PMID:
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Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe.
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Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
PLoS Pathog.
2020 Aug;16(8):e1008753. doi: 10.1371/journal.ppat.1008753. eCollection 2020 Aug. PubMed PMID:
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Structural basis of a shared antibody response to SARS-CoV-2.
Science.
2020 Aug 28;369(6507):1119-1123. doi: 10.1126/science.abd2321. Epub 2020 Jul 13. PubMed PMID:
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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
Science.
2020 Aug 21;369(6506):956-963. doi: 10.1126/science.abc7520. Epub 2020 Jun 15. PubMed PMID:
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A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
bioRxiv.
2020 Aug 16;. doi: 10.1101/2020.08.15.252320. PubMed PMID:
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Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins.
Bioorg Med Chem Lett.
2020 Aug 15;30(16):127356. doi: 10.1016/j.bmcl.2020.127356. Epub 2020 Jun 16. PubMed PMID:
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An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc Natl Acad Sci U S A.
2020 Aug 4;117(31):18431-18438. doi: 10.1073/pnas.2006893117. Epub 2020 Jul 20. PubMed PMID:
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Influenza Hemagglutinin Structures and Antibody Recognition.
Cold Spring Harb Perspect Med.
2020 Aug 3;10(8). doi: 10.1101/cshperspect.a038778. Review. PubMed PMID:
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Innovations in structure-based antigen design and immune monitoring for next generation vaccines.
Curr Opin Immunol.
2020 Aug;65:50-56. doi: 10.1016/j.coi.2020.03.013. Epub 2020 Apr 22. Review. PubMed PMID:
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An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain.
bioRxiv.
2020 Jul 27;. doi: 10.1101/2020.07.26.222232. PubMed PMID:
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An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv.
2020 Jul;6(30):eabb5642. doi: 10.1126/sciadv.abb5642. eCollection 2020 Jul. PubMed PMID:
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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity.
medRxiv.
2020 Jul 15;. doi: 10.1101/2020.07.13.20153114. PubMed PMID:
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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity.
ArXiv.
2020 Jul 14;. PubMed PMID:
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Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science.
2020 Jun 19;368(6497):1335-1340. doi: 10.1126/science.aaz5143. PubMed PMID:
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Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc Natl Acad Sci U S A.
2020 Jun 16;117(24):13499-13508. doi: 10.1073/pnas.1918844117. Epub 2020 May 28. PubMed PMID:
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Structural basis of a public antibody response to SARS-CoV-2.
bioRxiv.
2020 Jun 9;. doi: 10.1101/2020.06.08.141267. PubMed PMID:
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Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections.
Cell Rep.
2020 Jun 2;31(9):107725. doi: 10.1016/j.celrep.2020.107725. Epub 2020 May 18. PubMed PMID:
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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation.
Nat Commun.
2020 May 27;11(1):2688. doi: 10.1038/s41467-020-16567-0. PubMed PMID:
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Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv.
2020 May;6(22):eaba0468. doi: 10.1126/sciadv.aba0468. eCollection 2020 May. PubMed PMID:
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A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.
Science.
2020 May 8;368(6491):630-633. doi: 10.1126/science.abb7269. Epub 2020 Apr 3. PubMed PMID:
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HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep.
2020 Apr 28;31(4):107583. doi: 10.1016/j.celrep.2020.107583. PubMed PMID:
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Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv.
2020 Apr;6(16):eaaz6225. doi: 10.1126/sciadv.aaz6225. eCollection 2020 Apr. PubMed PMID:
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Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020.
Euro Surveill.
2020 Apr;25(16). doi: 10.2807/1560-7917.ES.2020.25.16.2000421. PubMed PMID:
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PMC7189648.
The Impact of Sustained Immunization Regimens on the Antibody Response to Oligomannose Glycans.
ACS Chem Biol.
2020 Mar 20;15(3):789-798. doi: 10.1021/acschembio.0c00053. Epub 2020 Mar 9. PubMed PMID:
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PMC7091532.
Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.
J Virol.
2020 Mar 17;94(7). doi: 10.1128/JVI.01861-19. Print 2020 Mar 17. PubMed PMID:
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PMC7081899.
Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections.
bioRxiv.
2020 Mar 17;. doi: 10.1101/2020.03.15.993097. PubMed PMID:
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Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
PLoS Pathog.
2020 Mar;16(3):e1008373. doi: 10.1371/journal.ppat.1008373. eCollection 2020 Mar. PubMed PMID:
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PMC7082059.
Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape.
Nat Commun.
2020 Mar 6;11(1):1233. doi: 10.1038/s41467-020-15102-5. PubMed PMID:
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Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin.
J Virol.
2020 Feb 28;94(6). doi: 10.1128/JVI.01883-19. Print 2020 Feb 28. PubMed PMID:
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Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein.
J Mol Biol.
2020 Feb 14;432(4):1048-1063. doi: 10.1016/j.jmb.2019.12.029. Epub 2019 Dec 27. PubMed PMID:
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A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry.
2019 Dec 24;58(51):5160-5172. doi: 10.1021/acs.biochem.9b00932. Epub 2019 Dec 13. PubMed PMID:
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Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans.
Cell Rep.
2019 Dec 24;29(13):4460-4470.e8. doi: 10.1016/j.celrep.2019.11.084. PubMed PMID:
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Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice.
Cell Host Microbe.
2019 Dec 11;26(6):715-728.e8. doi: 10.1016/j.chom.2019.10.003. Epub 2019 Nov 19. PubMed PMID:
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Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe.
2019 Dec 11;26(6):729-738.e4. doi: 10.1016/j.chom.2019.10.002. Epub 2019 Nov 19. PubMed PMID:
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A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science.
2019 Dec 6;366(6470). doi: 10.1126/science.aax4380. Epub 2019 Oct 31. PubMed PMID:
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An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun.
2019 Nov 26;10(1):5389. doi: 10.1038/s41467-019-12973-1. PubMed PMID:
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Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science.
2019 Oct 25;366(6464):499-504. doi: 10.1126/science.aay0678. PubMed PMID:
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Exploitation of glycosylation in enveloped virus pathobiology.
Biochim Biophys Acta Gen Subj.
2019 Oct;1863(10):1480-1497. doi: 10.1016/j.bbagen.2019.05.012. Epub 2019 May 20. Review. PubMed PMID:
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Structures of single-layer β-sheet proteins evolved from β-hairpin repeats.
Protein Sci.
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Structure and Dynamics of Stacking Interactions in an Antibody Binding Site.
Biochemistry.
2019 Jul 9;58(27):2987-2995. doi: 10.1021/acs.biochem.9b00119. Epub 2019 Jun 19. PubMed PMID:
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Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure.
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