My Bibliography

select

Takahashi K, Murakami S, Chikashige Y, Funabiki H, Niwa O, Yanagida M. A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere. Mol Biol Cell. 1992 Jul;3(7):819-35. doi: 10.1091/mbc.3.7.819. PubMed PMID: 1515677; PubMed Central PMCID: PMC275637.

select

Funabiki H, Hagan I, Uzawa S, Yanagida M. Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J Cell Biol. 1993 Jun;121(5):961-76. doi: 10.1083/jcb.121.5.961. PubMed PMID: 8388878; PubMed Central PMCID: PMC2119680.

select

Chikashige Y, Ding DQ, Funabiki H, Haraguchi T, Mashiko S, Yanagida M, Hiraoka Y. Telomere-led premeiotic chromosome movement in fission yeast. Science. 1994 Apr 8;264(5156):270-3. doi: 10.1126/science.8146661. PubMed PMID: 8146661.

select

Funabiki H, Yamano H, Kumada K, Nagao K, Hunt T, Yanagida M. Cut2 proteolysis required for sister-chromatid seperation in fission yeast. Nature. 1996 May 30;381(6581):438-41. doi: 10.1038/381438a0. PubMed PMID: 8632802.

select

Funabiki H, Kumada K, Yanagida M. Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J. 1996 Dec 2;15(23):6617-28. PubMed PMID: 8978688; PubMed Central PMCID: PMC452486.

select

Funabiki H, Yamano H, Nagao K, Tanaka H, Yasuda H, Hunt T, Yanagida M. Fission yeast Cut2 required for anaphase has two destruction boxes. EMBO J. 1997 Oct 1;16(19):5977-87. doi: 10.1093/emboj/16.19.5977. PubMed PMID: 9312055; PubMed Central PMCID: PMC1170228.

select

Kumada K, Nakamura T, Nagao K, Funabiki H, Nakagawa T, Yanagida M. Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis. Curr Biol. 1998 May 21;8(11):633-41. doi: 10.1016/s0960-9822(98)70250-7. PubMed PMID: 9635190.

select

Funabiki H, Murray AW. The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement. Cell. 2000 Aug 18;102(4):411-24. doi: 10.1016/s0092-8674(00)00047-7. PubMed PMID: 10966104.

select

Sampath SC, Ohi R, Leismann O, Salic A, Pozniakovski A, Funabiki H. The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell. 2004 Jul 23;118(2):187-202. doi: 10.1016/j.cell.2004.06.026. PubMed PMID: 15260989.

select

Funabiki H. Two birds with one stone--dealing with nuclear transport and spindle assembly. Cell. 2005 Apr 22;121(2):157-8. doi: 10.1016/j.cell.2005.04.003. Review. PubMed PMID: 15851021.

select

Fischle W, Tseng BS, Dormann HL, Ueberheide BM, Garcia BA, Shabanowitz J, Hunt DF, Funabiki H, Allis CD. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature. 2005 Dec 22;438(7071):1116-22. doi: 10.1038/nature04219. Epub 2005 Oct 12. PubMed PMID: 16222246.

select

Dormann HL, Tseng BS, Allis CD, Funabiki H, Fischle W. Dynamic regulation of effector protein binding to histone modifications: the biology of HP1 switching. Cell Cycle. 2006 Dec;5(24):2842-51. doi: 10.4161/cc.5.24.3540. Epub 2006 Dec 15. PubMed PMID: 17172865.

select

Kelly AE, Sampath SC, Maniar TA, Woo EM, Chait BT, Funabiki H. Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell. 2007 Jan;12(1):31-43. doi: 10.1016/j.devcel.2006.11.001. PubMed PMID: 17199039; PubMed Central PMCID: PMC1892535.

select

Woo EM, Fenyo D, Kwok BH, Funabiki H, Chait BT. Efficient identification of phosphorylation by mass spectrometric phosphopeptide fingerprinting. Anal Chem. 2008 Apr 1;80(7):2419-25. doi: 10.1021/ac702059p. Epub 2008 Mar 6. PubMed PMID: 18321079.

select

Postow L, Ghenoiu C, Woo EM, Krutchinsky AN, Chait BT, Funabiki H. Ku80 removal from DNA through double strand break-induced ubiquitylation. J Cell Biol. 2008 Aug 11;182(3):467-79. doi: 10.1083/jcb.200802146. Epub 2008 Aug 4. PubMed PMID: 18678709; PubMed Central PMCID: PMC2500133.

select

Kelly AE, Funabiki H. Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view. Curr Opin Cell Biol. 2009 Feb;21(1):51-8. doi: 10.1016/j.ceb.2009.01.004. Review. PubMed PMID: 19185479; PubMed Central PMCID: PMC2801027.

select

Postow L, Woo EM, Chait BT, Funabiki H. Identification of SMARCAL1 as a component of the DNA damage response. J Biol Chem. 2009 Dec 18;284(51):35951-61. doi: 10.1074/jbc.M109.048330. PubMed PMID: 19841479; PubMed Central PMCID: PMC2791023.

select

Tseng BS, Tan L, Kapoor TM, Funabiki H. Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell. 2010 Jun 15;18(6):903-12. doi: 10.1016/j.devcel.2010.05.018. PubMed PMID: 20627073; PubMed Central PMCID: PMC2905387.

select

Kelly AE, Ghenoiu C, Xue JZ, Zierhut C, Kimura H, Funabiki H. Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science. 2010 Oct 8;330(6001):235-9. doi: 10.1126/science.1189505. Epub 2010 Aug 12. PubMed PMID: 20705815; PubMed Central PMCID: PMC3177562.

select

Rosenberg JS, Cross FR, Funabiki H. KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint. Curr Biol. 2011 Jun 7;21(11):942-7. doi: 10.1016/j.cub.2011.04.011. PubMed PMID: 21640906; PubMed Central PMCID: PMC3109435.

select

Funabiki H. To Cut or NoCut in mitosis. Nat Rev Mol Cell Biol. 2011 Jun 29;12(8):463. doi: 10.1038/nrm3148. PubMed PMID: 21712842.

select

Du J, Kelly AE, Funabiki H, Patel DJ. Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin. Structure. 2012 Jan 11;20(1):185-95. doi: 10.1016/j.str.2011.12.001. PubMed PMID: 22244766; PubMed Central PMCID: PMC3684423.

select

Rivera T, Ghenoiu C, Rodríguez-Corsino M, Mochida S, Funabiki H, Losada A. Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex. EMBO J. 2012 Mar 21;31(6):1467-79. doi: 10.1038/emboj.2012.4. Epub 2012 Jan 24. PubMed PMID: 22274615; PubMed Central PMCID: PMC3321187.

select

Carmena M, Wheelock M, Funabiki H, Earnshaw WC. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol. 2012 Dec;13(12):789-803. doi: 10.1038/nrm3474. Review. PubMed PMID: 23175282; PubMed Central PMCID: PMC3729939.

select

Postow L, Funabiki H. An SCF complex containing Fbxl12 mediates DNA damage-induced Ku80 ubiquitylation. Cell Cycle. 2013 Feb 15;12(4):587-95. doi: 10.4161/cc.23408. Epub 2013 Jan 16. PubMed PMID: 23324393; PubMed Central PMCID: PMC3594259.

select

Funabiki H, Wynne DJ. Making an effective switch at the kinetochore by phosphorylation and dephosphorylation. Chromosoma. 2013 Jun;122(3):135-58. doi: 10.1007/s00412-013-0401-5. Epub 2013 Mar 20. Review. PubMed PMID: 23512483; PubMed Central PMCID: PMC3665160.

select

Xue JZ, Woo EM, Postow L, Chait BT, Funabiki H. Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly. Dev Cell. 2013 Oct 14;27(1):47-59. doi: 10.1016/j.devcel.2013.08.002. Epub 2013 Sep 26. PubMed PMID: 24075807; PubMed Central PMCID: PMC3800493.

select

Ghenoiu C, Wheelock MS, Funabiki H. Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis. Mol Cell. 2013 Dec 12;52(5):734-45. doi: 10.1016/j.molcel.2013.10.002. Epub 2013 Oct 31. PubMed PMID: 24184212; PubMed Central PMCID: PMC3865225.

select

Xue JZ, Funabiki H. Nuclear assembly shaped by microtubule dynamics. Nucleus. 2014 Jan-Feb;5(1):40-6. doi: 10.4161/nucl.28168. Epub 2014 Feb 10. PubMed PMID: 24637392; PubMed Central PMCID: PMC4028354.

select

Zierhut C, Jenness C, Kimura H, Funabiki H. Nucleosomal regulation of chromatin composition and nuclear assembly revealed by histone depletion. Nat Struct Mol Biol. 2014 Jul;21(7):617-25. doi: 10.1038/nsmb.2845. Epub 2014 Jun 22. PubMed PMID: 24952593; PubMed Central PMCID: PMC4082469.

select

Wynne DJ, Funabiki H. Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components. J Cell Biol. 2015 Sep 14;210(6):899-916. doi: 10.1083/jcb.201506020. PubMed PMID: 26347137; PubMed Central PMCID: PMC4576862.

select

Zierhut C, Funabiki H. Nucleosome functions in spindle assembly and nuclear envelope formation. Bioessays. 2015 Oct;37(10):1074-85. doi: 10.1002/bies.201500045. Epub 2015 Jul 29. Review. PubMed PMID: 26222742; PubMed Central PMCID: PMC4730913.

select

van den Boom J, Wolf M, Weimann L, Schulze N, Li F, Kaschani F, Riemer A, Zierhut C, Kaiser M, Iliakis G, Funabiki H, Meyer H. VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair. Mol Cell. 2016 Oct 6;64(1):189-198. doi: 10.1016/j.molcel.2016.08.037. PubMed PMID: 27716483; PubMed Central PMCID: PMC5161236.

select

Wynne DJ, Funabiki H. Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy. Mol Biol Cell. 2016 Nov 7;27(22):3395-3404. doi: 10.1091/mbc.E16-02-0130. Epub 2016 May 11. PubMed PMID: 27170176; PubMed Central PMCID: PMC5221576.

select

Funabiki H. Interphase Positioning of Centromeres Sets Up Spindle Assembly. Dev Cell. 2016 Dec 5;39(5):527-528. doi: 10.1016/j.devcel.2016.11.014. PubMed PMID: 27923119.

select

Giunta S, Funabiki H. Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1928-1933. doi: 10.1073/pnas.1615133114. Epub 2017 Feb 6. PubMed PMID: 28167779; PubMed Central PMCID: PMC5338446.

select

Wheelock MS, Wynne DJ, Tseng BS, Funabiki H. Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression. J Cell Biol. 2017 Apr 3;216(4):925-941. doi: 10.1083/jcb.201609061. Epub 2017 Mar 17. PubMed PMID: 28314740; PubMed Central PMCID: PMC5379950.

select

Skamagki M, Correia C, Yeung P, Baslan T, Beck S, Zhang C, Ross CA, Dang L, Liu Z, Giunta S, Chang TP, Wang J, Ananthanarayanan A, Bohndorf M, Bosbach B, Adjaye J, Funabiki H, Kim J, Lowe S, Collins JJ, Lu CW, Li H, Zhao R, Kim K. ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. Nat Cell Biol. 2017 Sep;19(9):1037-1048. doi: 10.1038/ncb3598. Epub 2017 Aug 28. PubMed PMID: 28846095; PubMed Central PMCID: PMC5843481.

select

Jenness C, Giunta S, Müller MM, Kimura H, Muir TW, Funabiki H. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E876-E885. doi: 10.1073/pnas.1717509115. Epub 2018 Jan 16. PubMed PMID: 29339483; PubMed Central PMCID: PMC5798369.

select

Funabiki H, Jenness C, Zierhut C. Nucleosome-Dependent Pathways That Control Mitotic Progression. Cold Spring Harb Symp Quant Biol. 2017;82:173-185. doi: 10.1101/sqb.2017.82.034512. Epub 2018 Mar 7. PubMed PMID: 29514983.

select

Jenness C, Wynne DJ, Funabiki H. Protein Immunodepletion and Complementation in Xenopus laevis Egg Extracts. Cold Spring Harb Protoc. 2018 Sep 4;2018(9). doi: 10.1101/pdb.prot097113. PubMed PMID: 29382808; PubMed Central PMCID: PMC9040579.

select

Unoki M, Funabiki H, Velasco G, Francastel C, Sasaki H. CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome. J Clin Invest. 2019 Jan 2;129(1):78-92. doi: 10.1172/JCI99751. Epub 2018 Nov 19. PubMed PMID: 30307408; PubMed Central PMCID: PMC6307953.

select

Funabiki H. Correcting aberrant kinetochore microtubule attachments: a hidden regulation of Aurora B on microtubules. Curr Opin Cell Biol. 2019 Jun;58:34-41. doi: 10.1016/j.ceb.2018.12.007. Epub 2019 Jan 23. Review. PubMed PMID: 30684807; PubMed Central PMCID: PMC6646109.

select

Zierhut C, Yamaguchi N, Paredes M, Luo JD, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019 Jul 11;178(2):302-315.e23. doi: 10.1016/j.cell.2019.05.035. PubMed PMID: 31299200; PubMed Central PMCID: PMC6693521.

select

Zierhut C, Funabiki H. Regulation and Consequences of cGAS Activation by Self-DNA. Trends Cell Biol. 2020 Aug;30(8):594-605. doi: 10.1016/j.tcb.2020.05.006. Epub 2020 Jun 13. Review. PubMed PMID: 32546434; PubMed Central PMCID: PMC7368801.

select

Kujirai T, Zierhut C, Takizawa Y, Kim R, Negishi L, Uruma N, Hirai S, Funabiki H, Kurumizaka H. Structural basis for the inhibition of cGAS by nucleosomes. Science. 2020 Oct 23;370(6515):455-458. doi: 10.1126/science.abd0237. Epub 2020 Sep 10. PubMed PMID: 32912999; PubMed Central PMCID: PMC7584773.

select

Arimura Y, Shih RM, Froom R, Funabiki H. Nucleosome structural variations in interphase and metaphase chromosomes. Version: 2. [preprint]. 2020 November; [revised 2020 November]: [33 pages]. Available from: https://www.biorxiv.org/content/10.1101/2020.11.12.380386v2. doi: 10.1101/2020.11.12.380386.

select

Choppakatla P, Dekker B, Cutts EE, Vannini A, Dekker J, Funabiki H. Linker histone H1.8 inhibits chromatin-binding of condensins and DNA topoisomerase II to tune chromosome compaction and individualization. Version: 1. [preprint]. 2020 December. [34 pages]. Available from: https://www.biorxiv.org/content/10.1101/2020.12.20.423657v1. doi: 10.1101/2020.12.20.423657.

select

Giunta S, Hervé S, White RR, Wilhelm T, Dumont M, Scelfo A, Gamba R, Wong CK, Rancati G, Smogorzewska A, Funabiki H, Fachinetti D. CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10). doi: 10.1073/pnas.2015634118. PubMed PMID: 33653953; PubMed Central PMCID: PMC7958389.

select

Choppakatla P, Dekker B, Cutts EE, Vannini A, Dekker J, Funabiki H. Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization. Elife. 2021 Aug 18;10. doi: 10.7554/eLife.68918. PubMed PMID: 34406118; PubMed Central PMCID: PMC8416026.