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Hejazi L, Wong JW, Cheng D, Proschogo N, Ebrahimi D, Garner B, Don AS. Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains. Biochem J. 2011 Aug 15;438(1):165-75. doi: 10.1042/BJ20110566. PubMed PMID: 21639855.
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Dervishi E, Zhang G, Hailemariam D, Goldansaz SA, Deng Q, Dunn SM, Ametaj BN. Alterations in innate immunity reactants and carbohydrate and lipid metabolism precede occurrence of metritis in transition dairy cows. Res Vet Sci. 2016 Feb;104:30-9. doi: 10.1016/j.rvsc.2015.11.004. Epub 2015 Nov 12. PubMed PMID: 26850534.
Dervishi E, Zhang G, Hailemariam D, Dunn SM, Ametaj BN. Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows. J Anim Sci Biotechnol. 2016;7:26. doi: 10.1186/s40104-016-0085-9. eCollection 2016. PubMed PMID: 27119014; PubMed Central PMCID: PMC4845382.
Zhang G, Hailemariam D, Dervishi E, Goldansaz SA, Deng Q, Dunn SM, Ametaj BN. Dairy cows affected by ketosis show alterations in innate immunity and lipid and carbohydrate metabolism during the dry off period and postpartum. Res Vet Sci. 2016 Aug;107:246-256. doi: 10.1016/j.rvsc.2016.06.012. Epub 2016 Jun 20. PubMed PMID: 27474003.
Zhang G, Dervish E, Mandal R, Wishart DS, Ametaj BN. Metallotyping of ketotic dairy cows reveals major alterations preceding, associating, and following the disease occurrence. Metabolomics. 2017; 13:97. doi: 10.1007/s11306-017-1237-4.
Zhang G, Dervish E, Dunn SM, Mandal R, Liu P, Han B, Wishart DS, Ametaj BN. Metabotyping reveals distinct metabolic alterations in ketotic cows and identifies early predictive serum biomarkers for the risk of disease. Metabolomics. 2017; 13:43. doi: 10.1007/s11306-017-1180-4.
Dervishi E, Zhang G, Dunn SM, Mandal R, Wishart DS, Ametaj BN. GC-MS Metabolomics Identifies Metabolite Alterations That Precede Subclinical Mastitis in the Blood of Transition Dairy Cows. J Proteome Res. 2017 Feb 3;16(2):433-446. doi: 10.1021/acs.jproteome.6b00538. Epub 2016 Nov 28. PubMed PMID: 28152597.
Zhang G, Saito R, Sharma K. A metabolite-GWAS (mGWAS) approach to unveil chronic kidney disease progression. Kidney Int. 2017 Jun;91(6):1274-1276. doi: 10.1016/j.kint.2017.03.022. PubMed PMID: 28501300; PubMed Central PMCID: PMC5989707.
Zhang G, Deng Q, Mandal R, Wishart DS, Ametaj BN. DI/LC-MS/MS-Based Metabolic Profiling for Identification of Early Predictive Serum Biomarkers of Metritis in Transition Dairy Cows. J Agric Food Chem. 2017 Sep 27;65(38):8510-8521. doi: 10.1021/acs.jafc.7b02000. Epub 2017 Sep 18. PubMed PMID: 28862839.
Hailemariam D, Zhang G, Mandal R, Wishart DS, Ametaj BN. Identification of serum metabolites associated with the risk of metritis in transition dairy cows. Canadian Journal of Animal Science. 2018; 98(3):525-537. doi: 10.1139/cjas-2017-0069.
Zhang G, Darshi M, Sharma K. The Warburg Effect in Diabetic Kidney Disease. Semin Nephrol. 2018 Mar;38(2):111-120. doi: 10.1016/j.semnephrol.2018.01.002. Review. PubMed PMID: 29602394; PubMed Central PMCID: PMC5973839.
Zhang G, Dervishi E, Ametaj BN. Reprint of Milk fever in dairy cows is preceded by activation of innate immunity and alterations in carbohydrate metabolism prior to disease occurrence. Res Vet Sci. 2018 Feb;116:72-82. doi: 10.1016/j.rvsc.2018.02.013. Epub 2018 Mar 6. PubMed PMID: 29519703.
Zhang G, Dervishi E, Ametaj BN. Milk fever in dairy cows is preceded by activation of innate immunity and alterations in carbohydrate metabolism prior to disease occurrence. Res Vet Sci. 2018 Apr;117:167-177. doi: 10.1016/j.rvsc.2017.12.008. Epub 2017 Dec 19. PubMed PMID: 29277015.
Dervishi E, Zhang G, Mandal R, Wishart DS, Ametaj BN. Targeted metabolomics: new insights into pathobiology of retained placenta in dairy cows and potential risk biomarkers. Animal. 2018 May;12(5):1050-1059. doi: 10.1017/S1751731117002506. Epub 2017 Oct 16. PubMed PMID: 29032783.
Dervishi E, Zhang G, Hailemariam D, Mandal R, Wishart DS, Ametaj BN. Urine metabolic fingerprinting can be used to predict the risk of metritis and highlight the pathobiology of the disease in dairy cows. Metabolomics. 2018 Jun 8;14(6):83. doi: 10.1007/s11306-018-1379-z. PubMed PMID: 30830348.
Zhang G, Zhang J, DeHoog RJ, Pennathur S, Anderton CR, Venkatachalam MA, Alexandrov T, Eberlin LS, Sharma K. DESI-MSI and METASPACE indicates lipid abnormalities and altered mitochondrial membrane components in diabetic renal proximal tubules. Metabolomics. 2020 Jan 10;16(1):11. doi: 10.1007/s11306-020-1637-8. PubMed PMID: 31925564; PubMed Central PMCID: PMC7301343.
Dervishi E, Zhang G, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Serum metabolic fingerprinting of pre-lameness dairy cows by GC-MS reveals typical profiles that can identify susceptible cows. J Proteomics. 2020 Feb 20;213:103620. doi: 10.1016/j.jprot.2019.103620. Epub 2019 Dec 14. PubMed PMID: 31846765.
Veličković D, Zhang G, Bezbradica D, Bhattacharjee A, Paša-Tolić L, Sharma K, Alexandrov T, Anderton CR. Response Surface Methodology As a New Approach for Finding Optimal MALDI Matrix Spraying Parameters for Mass Spectrometry Imaging. J Am Soc Mass Spectrom. 2020 Mar 4;31(3):508-516. doi: 10.1021/jasms.9b00074. Epub 2020 Feb 6. PubMed PMID: 32126772; PubMed Central PMCID: PMC7293970.
Zhang G, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Urinary metabolomics around parturition identifies metabolite alterations in dairy cows affected postpartum by lameness: Preliminary study. Dairy. 2020 March; 1(1):2.
Zwierzchowski G, Zhang G, Mandal R, Wishart DS, Ametaj BN. Mass-spec-based urinary metabotyping around parturition identifies screening biomarkers for subclinical mastitis in dairy cows. Res Vet Sci. 2020 Apr;129:39-52. doi: 10.1016/j.rvsc.2020.01.001. Epub 2020 Jan 3. PubMed PMID: 31931262.
Zwierzchowski G, Zhang G, Mandal R, Wishart DS, Ametaj BN. Milk Metabotyping Identifies Metabolite Alterations in the Whole Raw Milk of Dairy Cows with Lameness. J Agric Food Chem. 2020 Apr 15;68(15):4507-4514. doi: 10.1021/acs.jafc.9b08312. Epub 2020 Apr 3. PubMed PMID: 32223231.
Zhang G, Ametaj BN. Ketosis an old story under a new approach. Dairy. 2020 May; 1(1):42-60. doi: https://doi.org/10.3390/dairy1010005.
Miyamoto S, Zhang G, Hall D, Oates PJ, Maity S, Madesh M, Han X, Sharma K. Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease. J Biol Chem. 2020 May 22;295(21):7249-7260. doi: 10.1074/jbc.RA119.011110. Epub 2020 Apr 10. PubMed PMID: 32277051; PubMed Central PMCID: PMC7247302.
Zhang G, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Serum metabolomics identifies metabolite panels that differentiate lame dairy cows from healthy ones. Metabolomics. 2020 Jun 13;16(6):73. doi: 10.1007/s11306-020-01693-z. PubMed PMID: 32535675.
Eckel EF, Zhang G, Dervishi E, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Urinary metabolomics fingerprinting around parturition identifies metabolites that differentiate lame dairy cows from healthy ones. Animal. 2020 Oct;14(10):2138-2149. doi: 10.1017/S1751731120001172. Epub 2020 Jun 5. PubMed PMID: 32498732.
Lukowski JK, Pamreddy A, Velickovic D, Zhang G, Pasa-Tolic L, Alexandrov T, Sharma K, Anderton CR. Storage Conditions of Human Kidney Tissue Sections Affect Spatial Lipidomics Analysis Reproducibility. J Am Soc Mass Spectrom. 2020 Dec 2;31(12):2538-2546. doi: 10.1021/jasms.0c00256. Epub 2020 Sep 25. PubMed PMID: 32897710; PubMed Central PMCID: PMC8162764.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics. 2021 Jan 1;53(1):1-11. doi: 10.1152/physiolgenomics.00104.2020. Epub 2020 Nov 16. PubMed PMID: 33197228; PubMed Central PMCID: PMC7847045.
Zhang G, Mandal R, Wishart DS, Ametaj BN. A Multi-Platform Metabolomics Approach Identifies Urinary Metabolite Signatures That Differentiate Ketotic From Healthy Dairy Cows. Front Vet Sci. 2021;8:595983. doi: 10.3389/fvets.2021.595983. eCollection 2021. PubMed PMID: 33575283; PubMed Central PMCID: PMC7871000.
de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J. Rationale and design of the Kidney Precision Medicine Project. Kidney Int. 2021 Mar;99(3):498-510. doi: 10.1016/j.kint.2020.08.039. PubMed PMID: 33637194; PubMed Central PMCID: PMC8330551.
Tuttle KR, Bebiak J, Brown K, Campbell C, Dighe A, Hyashi L, Jefferson N, Roberts GV, Stutzke C, Knight R. Patient perspectives and involvement in precision medicine research. Kidney Int. 2021 Mar;99(3):511-514. doi: 10.1016/j.kint.2020.10.036. PubMed PMID: 33637195.
Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis. Kidney Int. 2021 Sep;100(3):672-683. doi: 10.1016/j.kint.2021.04.037. Epub 2021 May 27. PubMed PMID: 34051265; PubMed Central PMCID: PMC8384690.
Zhang G, Tobolski D, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Identification of Serum-Predictive Biomarkers for Subclinical Mastitis in Dairy Cows and New Insights into the Pathobiology of the Disease. J Agric Food Chem. 2022 Feb 9;70(5):1724-1746. doi: 10.1021/acs.jafc.1c07281. Epub 2022 Jan 31. PubMed PMID: 35098717.
Menon R, Bomback AS, Lake BB, Stutzke C, Grewenow SM, Menez S, D'Agati VD, Jain S. Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation. Kidney Int. 2022 Jun;101(6):1116-1125. doi: 10.1016/j.kint.2022.03.011. Epub 2022 Mar 23. PubMed PMID: 35339536; PubMed Central PMCID: PMC9769136.
Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, Anjani K, Parikh S, Sigdel TK, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto EA, Rivera M, Rose MP, Anderton CR, Shapiro JP, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer IH, Hodgin JB, Barisoni L, Naik AS, Sharma K, Sarwal MM, Zhang K, Himmelfarb J, Rovin B, El-Achkar TM, Laszik Z, He JC, Dagher PC, Valerius MT, Jain S, Satlin LM, Troyanskaya OG, Kretzler M, Iyengar R, Azeloglu EU. A reference tissue atlas for the human kidney. Sci Adv. 2022 Jun 10;8(23):eabn4965. doi: 10.1126/sciadv.abn4965. Epub 2022 Jun 8. PubMed PMID: 35675394; PubMed Central PMCID: PMC9176741.
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R. Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients. J Clin Invest. 2023 Oct 16;133(20). doi: 10.1172/JCI170341. PubMed PMID: 37616058; PubMed Central PMCID: PMC10575723.
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