My Bibliography

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Li JH, Forghani R, Bure L, Wojtkiewicz GR, Wu Y, Iwamoto Y, Ali M, Li A, Wang C, Jalali Motlagh N, Papadakis AI, Pusztaszeri MP, Spatz A, Curtin H, Cheng YS, Chen JW. Molecular immuno-imaging improves tumor detection in head and neck cancer. FASEB J. 2022 Jan;36(1):e22092. doi: 10.1096/fj.202100864R. PubMed PMID: 34919761; PubMed Central PMCID: PMC9584652.

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Wang J, Jalali Motlagh N, Wang C, Wojtkiewicz GR, Schmidt S, Chau C, Narsimhan R, Kullenberg EG, Zhu C, Linnoila J, Yao Z, Chen JW. d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44). doi: 10.1073/pnas.2107663118. PubMed PMID: 34702739; PubMed Central PMCID: PMC8673064.

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Wang C, Cheng D, Jalali Motlagh N, Kuellenberg EG, Wojtkiewicz GR, Schmidt SP, Stocker R, Chen JW. Highly Efficient Activatable MRI Probe to Sense Myeloperoxidase Activity. J Med Chem. 2021 May 13;64(9):5874-5885. doi: 10.1021/acs.jmedchem.1c00038. Epub 2021 May 4. PubMed PMID: 33945286; PubMed Central PMCID: PMC8564765.

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Wang C, Pulli B, Jalali Motlagh N, Li A, Wojtkiewicz GR, Schmidt SP, Wu Y, Zeller MWG, Chen JW. A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales. Theranostics. 2019;9(25):7525-7536. doi: 10.7150/thno.36264. eCollection 2019. PubMed PMID: 31695784; PubMed Central PMCID: PMC6831463.

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Li A, Wu Y, Pulli B, Wojtkiewicz GR, Iwamoto Y, Wang C, Li JH, Ali M, Feng X, Yao Z, Chen JW. Myeloperoxidase Molecular MRI Reveals Synergistic Combination Therapy in Murine Experimental Autoimmune Neuroinflammation. Radiology. 2019 Oct;293(1):158-165. doi: 10.1148/radiol.2019182492. Epub 2019 Sep 3. PubMed PMID: 31478802; PubMed Central PMCID: PMC6776885.

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Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW. An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11966-11971. doi: 10.1073/pnas.1818434116. Epub 2019 May 23. PubMed PMID: 31123149; PubMed Central PMCID: PMC6575581.

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Hoffmann A, Pfeil J, Mueller AK, Jin J, Deumelandt K, Helluy X, Wang C, Heiland S, Platten M, Chen JW, Bendszus M, Breckwoldt MO. MRI of Iron Oxide Nanoparticles and Myeloperoxidase Activity Links Inflammation to Brain Edema in Experimental Cerebral Malaria. Radiology. 2019 Feb;290(2):359-367. doi: 10.1148/radiol.2018181051. Epub 2018 Dec 4. PubMed PMID: 30615566.

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Pulli B, Wojtkiewicz G, Iwamoto Y, Ali M, Zeller MW, Bure L, Wang C, Choi Y, Masia R, Guimaraes AR, Corey KE, Chen JW. Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease. Radiology. 2017 Aug;284(2):390-400. doi: 10.1148/radiol.2017160588. Epub 2017 Mar 30. PubMed PMID: 28358240; PubMed Central PMCID: PMC5548451.

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Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW. Myeloperoxidase Nuclear Imaging for Epileptogenesis. Radiology. 2017 Feb;282(2):614. doi: 10.1148/radiol.2017164044. PubMed PMID: 28099101; PubMed Central PMCID: PMC7006801.

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Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M. Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease. Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064. PubMed PMID: 28091604; PubMed Central PMCID: PMC5241815.

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Li A, Wu Y, Linnoila J, Pulli B, Wang C, Zeller M, Ali M, Lewandrowski GK, Li J, Tricot B, Keliher E, Wojtkiewicz GR, Fulci G, Feng X, Tannous BA, Yao Z, Chen JW. Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models. Cancer Immunol Immunother. 2016 Dec;65(12):1545-1554. doi: 10.1007/s00262-016-1911-9. Epub 2016 Oct 8. PubMed PMID: 27722909; PubMed Central PMCID: PMC5101144.

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Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW. Myeloperoxidase Nuclear Imaging for Epileptogenesis. Radiology. 2016 Mar;278(3):822-30. doi: 10.1148/radiol.2015141922. Epub 2015 Sep 23. PubMed PMID: 26397127; PubMed Central PMCID: PMC4770943.

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Li-ChunHsieh K, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW. Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis. J Neuroimmunol. 2015 Oct 15;287:36-42. doi: 10.1016/j.jneuroim.2015.08.006. Epub 2015 Aug 9. PubMed PMID: 26439960; PubMed Central PMCID: PMC4595933.

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Lowe MM, Mold JE, Kanwar B, Huang Y, Louie A, Pollastri MP, Wang C, Patel G, Franks DG, Schlezinger J, Sherr DH, Silverstone AE, Hahn ME, McCune JM. Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production. PLoS One. 2014;9(2):e87877. doi: 10.1371/journal.pone.0087877. eCollection 2014. PubMed PMID: 24498387; PubMed Central PMCID: PMC3912126.

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Ochiana SO, Gustafson A, Bland ND, Wang C, Russo MJ, Campbell RK, Pollastri MP. Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2582-4. doi: 10.1016/j.bmcl.2012.01.118. Epub 2012 Feb 9. PubMed PMID: 22377518; PubMed Central PMCID: PMC3307956.

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Wang C, Ashton TD, Gustafson A, Bland ND, Ochiana SO, Campbell RK, Pollastri MP. Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2579-81. doi: 10.1016/j.bmcl.2012.01.119. Epub 2012 Feb 9. PubMed PMID: 22370268; PubMed Central PMCID: PMC3307826.

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Bland ND, Wang C, Tallman C, Gustafson AE, Wang Z, Ashton TD, Ochiana SO, McAllister G, Cotter K, Fang AP, Gechijian L, Garceau N, Gangurde R, Ortenberg R, Ondrechen MJ, Campbell RK, Pollastri MP. Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness. J Med Chem. 2011 Dec 8;54(23):8188-94. doi: 10.1021/jm201148s. Epub 2011 Nov 8. PubMed PMID: 22023548; PubMed Central PMCID: PMC3228873.

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Barluenga S, Fontaine JG, Wang C, Aouadi K, Chen R, Beebe K, Neckers L, Winssinger N. Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem. 2009 Nov 23;10(17):2753-9. doi: 10.1002/cbic.200900494. PubMed PMID: 19856365; PubMed Central PMCID: PMC7556317.

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Wang C, Barluenga S, Koripelly GK, Fontaine JG, Chen R, Yu JC, Shen X, Chabala JC, Heck JV, Rubenstein A, Winssinger N. Synthesis of pochoxime prodrugs as potent HSP90 inhibitors. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3836-40. doi: 10.1016/j.bmcl.2009.04.030. Epub 2009 Apr 17. PubMed PMID: 19410458.

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Barluenga S, Wang C, Fontaine JG, Aouadi K, Beebe K, Tsutsumi S, Neckers L, Winssinger N. Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor. Angew Chem Int Ed Engl. 2008;47(23):4432-5. doi: 10.1002/anie.200800233. PubMed PMID: 18435518; PubMed Central PMCID: PMC2701509.

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Li CC, Wang CH, Liang B, Zhang XH, Deng LJ, Liang S, Chen JH, Wu YD, Yang Z. Synthetic study of 1,3-butadiene-based IMDA approach to construct a [5-7-6] tricyclic core and its application to the total synthesis of C8-epi-guanacastepene O. J Org Chem. 2006 Sep 1;71(18):6892-7. doi: 10.1021/jo060996h. PubMed PMID: 16930042.

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Wang C, Hu R, Liang S, Chen J, Yang Z, Pei J. Linear C2-Symmetric Polycyclic Benzodithiophene: Efficient, Highly Diversified Approaches and the Optical Properties. Tetrahedron. Lett.. 2005 November; 46(47):8153-8157. doi: 10.1016/j.tetlet.2005.09.107.

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Dai M, Liang B, Wang C, You Z, Xiang J, Dong G, Chen J, Yang Z. A Novel Thiourea Ligand Applied in the Pd-Catalyzed Heck, Suzuki and Suzuki Carbonylative Reactions. Adv. Synth. & Catal.. 2004 December; 346(13-15):1669-1673. doi: 10.1002/adsc.200404165.

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Dai M, Liang B, Wang C, Chen J, Yang Z. Synthesis of a novel C2-symmetric thiourea and its application in the Pd-catalyzed cross-coupling reactions with arenediazonium salts under aerobic conditions. Org Lett. 2004 Jan 22;6(2):221-4. doi: 10.1021/ol036182u. PubMed PMID: 14723533.

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Dai M, Wang C, Dong G, Xiang J, Luo T, Chen J, Yang Z. Development of Thiourea-based Ligands for the Palladium-Catalyzed Bis-(methoxycarbonylation) of Terminal Olefins. Eur. J. Org. Chem. 2003, 4346-4348.. 2003 November; 2003(22):4346-4348. doi: 10.1002/ejoc.200300543.

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. NIHMSID: NIHMS1842302.

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D-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America. . NIHMSID: NIHMS1842291.