Translational Genomics in Neurocritical Care: a Review.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. NIHMSID: NIHMS1564776.
Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation.
Epilepsia.
2007 Sep;48(9):1785-1800. doi: 10.1111/j.1528-1167.2007.01135.x. Epub 2007 May 23. PubMed PMID:
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Failure to validate association between 12p13 variants and ischemic stroke.
N Engl J Med.
2010 Apr 22;362(16):1547-50. doi: 10.1056/NEJMc0910050. PubMed PMID:
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Genetic variation and neuroimaging measures in Alzheimer disease.
Arch Neurol.
2010 Jun;67(6):677-85. doi: 10.1001/archneurol.2010.108. PubMed PMID:
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Chromosome 9p21 in ischemic stroke: population structure and meta-analysis.
Stroke.
2010 Jun;41(6):1123-31. doi: 10.1161/STROKEAHA.110.580589. Epub 2010 Apr 15. PubMed PMID:
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Principal-component analysis for assessment of population stratification in mitochondrial medical genetics.
Am J Hum Genet.
2010 Jun 11;86(6):904-17. doi: 10.1016/j.ajhg.2010.05.005. Epub 2010 May 27. PubMed PMID:
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Selective disruption of the cerebral neocortex in Alzheimer's disease.
PLoS One.
2010 Sep 23;5(9):e12853. doi: 10.1371/journal.pone.0012853. PubMed PMID:
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White matter hyperintensity burden and susceptibility to cerebral ischemia.
Stroke.
2010 Dec;41(12):2807-11. doi: 10.1161/STROKEAHA.110.595355. Epub 2010 Oct 14. PubMed PMID:
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Variants at APOE influence risk of deep and lobar intracerebral hemorrhage.
Ann Neurol.
2010 Dec;68(6):934-43. doi: 10.1002/ana.22134. PubMed PMID:
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Personalized approaches to clopidogrel therapy: are we there yet?.
Stroke.
2010 Dec;41(12):2997-3002. doi: 10.1161/STROKEAHA.110.594069. Epub 2010 Oct 28. Review. PubMed PMID:
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Common mitochondrial sequence variants in ischemic stroke.
Ann Neurol.
2011 Mar;69(3):471-80. doi: 10.1002/ana.22108. Epub 2010 Sep 13. PubMed PMID:
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The effect of survival bias on case-control genetic association studies of highly lethal diseases.
Circ Cardiovasc Genet.
2011 Apr;4(2):188-96. doi: 10.1161/CIRCGENETICS.110.957928. Epub 2011 Feb 3. PubMed PMID:
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Statin treatment and functional outcome after ischemic stroke: case-control and meta-analysis.
Stroke.
2011 May;42(5):1314-9. doi: 10.1161/STROKEAHA.110.605923. Epub 2011 Mar 17. Review. PubMed PMID:
21415396; PubMed Central PMCID:
PMC3093764.
Statin use and outcome after intracerebral hemorrhage: case-control study and meta-analysis.
Neurology.
2011 May 3;76(18):1581-8. doi: 10.1212/WNL.0b013e3182194be9. Epub 2011 Mar 30. PubMed PMID:
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APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study.
Lancet Neurol.
2011 Aug;10(8):702-9. doi: 10.1016/S1474-4422(11)70148-X. Epub 2011 Jul 6. PubMed PMID:
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Genome-wide association analysis of ischemic stroke in young adults.
G3 (Bethesda).
2011 Nov;1(6):505-14. doi: 10.1534/g3.111.001164. Epub 2011 Nov 1. PubMed PMID:
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Neurologic examination and extubation outcome in the neurocritical care unit.
Neurocrit Care.
2011 Dec;15(3):490-7. doi: 10.1007/s12028-010-9369-7. PubMed PMID:
20428967.
Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke?.
Stroke.
2012 Apr;43(4):980-6. doi: 10.1161/STROKEAHA.111.632075. Epub 2012 Feb 23. PubMed PMID:
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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
Neurobiol Aging.
2012 May;33(5):1017.e1-15. doi: 10.1016/j.neurobiolaging.2011.09.033. Epub 2011 Nov 4. PubMed PMID:
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TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.
Transl Stroke Res.
2012 Jul;3(Suppl 1):102-12. doi: 10.1007/s12975-012-0161-1. Epub 2012 Apr 12. PubMed PMID:
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Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.
Stroke.
2013 Feb;44(2):321-6. doi: 10.1161/STROKEAHA.112.675181. Epub 2013 Jan 15. PubMed PMID:
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Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage.
Stroke.
2013 Mar;44(3):612-9. doi: 10.1161/STROKEAHA.112.672089. Epub 2013 Jan 29. PubMed PMID:
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Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage.
Stroke.
2013 Jun;44(6):1578-83. doi: 10.1161/STROKEAHA.111.000089. Epub 2013 Apr 4. PubMed PMID:
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Novel insights into the genetics of intracerebral hemorrhage.
Stroke.
2013 Jun;44(6 Suppl 1):S137. doi: 10.1161/STROKEAHA.113.001912. PubMed PMID:
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Predictors of hematoma volume in deep and lobar supratentorial intracerebral hemorrhage.
JAMA Neurol.
2013 Aug;70(8):988-94. doi: 10.1001/jamaneurol.2013.98. PubMed PMID:
23733000; PubMed Central PMCID:
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Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.
Stroke.
2013 Oct;44(10):2694-702. doi: 10.1161/STROKEAHA.113.001857. Epub 2013 Sep 10. PubMed PMID:
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The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol.
Stroke.
2013 Oct;44(10):e120-5. doi: 10.1161/STROKEAHA.113.002332. Epub 2013 Sep 10. PubMed PMID:
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Apolipoprotein E, statins, and risk of intracerebral hemorrhage.
Stroke.
2013 Nov;44(11):3013-7. doi: 10.1161/STROKEAHA.113.001304. Epub 2013 Sep 5. PubMed PMID:
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Genome-wide linkage approach yields novel early onset myocardial infarction locus in East Asians.
Circ Cardiovasc Genet.
2013 Dec;6(6):531-2. doi: 10.1161/CIRCGENETICS.113.000378. PubMed PMID:
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Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.
Am J Hum Genet.
2014 Apr 3;94(4):511-21. doi: 10.1016/j.ajhg.2014.02.012. Epub 2014 Mar 20. PubMed PMID:
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Risk factors for computed tomography angiography spot sign in deep and lobar intracerebral hemorrhage are shared.
Stroke.
2014 Jun;45(6):1833-5. doi: 10.1161/STROKEAHA.114.005276. Epub 2014 May 13. PubMed PMID:
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Genetic variation of oxidative phosphorylation genes in stroke and Alzheimer's disease.
Neurobiol Aging.
2014 Aug;35(8):1956.e1-8. doi: 10.1016/j.neurobiolaging.2014.01.141. Epub 2014 Feb 5. PubMed PMID:
24650791; PubMed Central PMCID:
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APOE ε variants increase risk of warfarin-related intracerebral hemorrhage.
Neurology.
2014 Sep 23;83(13):1139-46. doi: 10.1212/WNL.0000000000000816. Epub 2014 Aug 22. PubMed PMID:
25150286; PubMed Central PMCID:
PMC4176027.
Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data.
Eur J Hum Genet.
2014 Oct;22(10):1239-42. doi: 10.1038/ejhg.2013.308. Epub 2014 Jan 22. PubMed PMID:
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Warfarin and statins are associated with hematoma volume in primary infratentorial intracerebral hemorrhage.
Neurocrit Care.
2014 Oct;21(2):192-9. doi: 10.1007/s12028-013-9839-9. PubMed PMID:
23839705; PubMed Central PMCID:
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Infection after intracerebral hemorrhage: risk factors and association with outcomes in the ethnic/racial variations of intracerebral hemorrhage study.
Stroke.
2014 Dec;45(12):3535-42. doi: 10.1161/STROKEAHA.114.006435. Epub 2014 Oct 14. PubMed PMID:
25316275; PubMed Central PMCID:
PMC4245453.
Recommendations from the international stroke genetics consortium, part 2: biological sample collection and storage.
Stroke.
2015 Jan;46(1):285-90. doi: 10.1161/STROKEAHA.114.006851. Epub 2014 Dec 9. PubMed PMID:
25492904; PubMed Central PMCID:
PMC4276505.
Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.
Neurology.
2015 Mar 3;84(9):918-26. doi: 10.1212/WNL.0000000000001309. Epub 2015 Feb 4. PubMed PMID:
25653287; PubMed Central PMCID:
PMC4351667.
Time is brain also counts for ICH.
Neurology.
2015 Mar 10;84(10):970-1. doi: 10.1212/WNL.0000000000001349. Epub 2015 Feb 6. PubMed PMID:
25663224.
APOE ε4 and lipid levels affect risk of recurrent nonlobar intracerebral hemorrhage.
Neurology.
2015 Jul 28;85(4):349-56. doi: 10.1212/WNL.0000000000001790. Epub 2015 Jun 26. PubMed PMID:
26115730; PubMed Central PMCID:
PMC4520812.
Rare Coding Variation and Risk of Intracerebral Hemorrhage.
Stroke.
2015 Aug;46(8):2299-301. doi: 10.1161/STROKEAHA.115.009838. Epub 2015 Jun 25. PubMed PMID:
26111891; PubMed Central PMCID:
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Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage.
Stroke.
2015 Aug;46(8):2302-4. doi: 10.1161/STROKEAHA.115.009880. Epub 2015 Jun 30. PubMed PMID:
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Association Between Blood Pressure Control and Risk of Recurrent Intracerebral Hemorrhage.
JAMA.
2015 Sep 1;314(9):904-12. doi: 10.1001/jama.2015.10082. PubMed PMID:
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Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage.
Stroke.
2015 Sep;46(9):2498-503. doi: 10.1161/STROKEAHA.115.009659. Epub 2015 Aug 4. PubMed PMID:
26243220; PubMed Central PMCID:
PMC4550492.
Response to Letter Regarding Article, "Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage".
Stroke.
2015 Nov;46(11):e244. doi: 10.1161/STROKEAHA.115.011288. Epub 2015 Oct 13. PubMed PMID:
26463690; PubMed Central PMCID:
PMC4709029.
Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study.
Stroke.
2015 Dec;46(12):3532-5. doi: 10.1161/STROKEAHA.115.010875. Epub 2015 Oct 15. PubMed PMID:
26470777; PubMed Central PMCID:
PMC4659755.
Small DWI lesions after intracerebral hemorrhage: Are perivascular spaces the missing link?.
Neurology.
2015 Dec 8;85(23):2004-5. doi: 10.1212/WNL.0000000000002181. Epub 2015 Nov 6. PubMed PMID:
26546631.
Oxidative phosphorylation and lacunar stroke: Genome-wide enrichment analysis of common variants.
Neurology.
2016 Jan 12;86(2):141-5. doi: 10.1212/WNL.0000000000002260. Epub 2015 Dec 16. PubMed PMID:
26674331; PubMed Central PMCID:
PMC4731691.
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.
Lancet Neurol.
2016 Feb;15(2):174-184. doi: 10.1016/S1474-4422(15)00338-5. Epub 2015 Dec 19. PubMed PMID:
26708676; PubMed Central PMCID:
PMC4912948.
Subacute decline in serum lipids precedes the occurrence of primary intracerebral hemorrhage.
Neurology.
2016 May 31;86(22):2034-41. doi: 10.1212/WNL.0000000000002716. Epub 2016 Apr 29. PubMed PMID:
27164693; PubMed Central PMCID:
PMC4891207.
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