My Bibliography

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Dai F, Wengler K, He X, Wang J, Yang J, Parsey RV, DeLorenzo C. Lack of association between pretreatment glutamate/GABA and major depressive disorder treatment response. Transl Psychiatry. 2025 Mar 2;15(1):71. doi: 10.1038/s41398-025-03292-9. PubMed PMID: 40025010; PubMed Central PMCID: PMC11873289.

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Ananth MR, Gardus JD, Huang C, Palekar N, Slifstein M, Zaborszky L, Parsey RV, Talmage DA, DeLorenzo C, Role LW. A central role for acetylcholine in entorhinal cortex function and dysfunction with age in humans and mice. Cell Rep. 2025 Feb 25;44(2):115249. doi: 10.1016/j.celrep.2025.115249. Epub 2025 Jan 30. PubMed PMID: 39891909.

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Clouston SAP, Vaska P, Babalola T, Gardus J 3rd, Huang C, Soriolo N, Fontana A, DeLorenzo C, Parsey R, Luft BJ. Glial activation among individuals with neurological post-acute sequelae of coronavirus disease 2019: A positron emission tomography study of brain fog using [(18)F]-FEPPA. Brain Behav Immun Health. 2025 Mar;44:100945. doi: 10.1016/j.bbih.2025.100945. eCollection 2025 Mar. PubMed PMID: 39897172; PubMed Central PMCID: PMC11786203.

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Madeira MM, Hage Z, Kokkosis AG, Nnah K, Guzman R, Schappell LE, Koliatsis D, Resutov E, Nadkarni NA, Rahme GJ, Tsirka SE. Oligodendroglia Are Primed for Antigen Presentation in Response to Chronic Stress-Induced Microglial-Derived Inflammation. Glia. 2025 Jun;73(6):1130-1147. doi: 10.1002/glia.24661. Epub 2024 Dec 24. PubMed PMID: 39719686; PubMed Central PMCID: PMC12014386.

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Lin K, Sunko D, Wang J, Yang J, Parsey RV, DeLorenzo C. Investigating the relationship between hippocampus/dentate gyrus volume and hypothalamus metabolism in participants with major depressive disorder. Sci Rep. 2024 May 9;14(1):10622. doi: 10.1038/s41598-024-61519-z. PubMed PMID: 38724691; PubMed Central PMCID: PMC11082185.

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Wang J, Wu DD, DeLorenzo C, Yang J. Examining factors related to low performance of predicting remission in participants with major depressive disorder using neuroimaging data and other clinical features. PLoS One. 2024;19(3):e0299625. doi: 10.1371/journal.pone.0299625. eCollection 2024. PubMed PMID: 38547128; PubMed Central PMCID: PMC10977765.

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Ananth M, Gardus J, Huang C, Palekar N, Slifstein M, Zaborszky L, Parsey R, Talmage D, DeLorenzo C, Role L. Loss of cholinergic input to the entorhinal cortex is an early indicator of cognitive impairment in natural aging of humans and mice. [preprint]. 2024 February. doi: 10.21203/rs.3.rs-3851086/v2.

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Frohman DFT, Nnah K, Tsirka SE. Intersection of Sex and Depression: Pathogenesis, Presentation, and Treatments. Handb Exp Pharmacol. 2023;282:163-180. doi: 10.1007/164_2023_670. PubMed PMID: 37439845; PubMed Central PMCID: PMC11519624.

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Donnelly BM, Hsu DT, Gardus J, Wang J, Yang J, Parsey RV, DeLorenzo C. Orbitofrontal and striatal metabolism, volume, thickness and structural connectivity in relation to social anhedonia in depression: A multimodal study. Neuroimage Clin. 2024;41:103553. doi: 10.1016/j.nicl.2023.103553. Epub 2023 Dec 15. PubMed PMID: 38134743; PubMed Central PMCID: PMC10777107.

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Volpi T, Maccioni L, Colpo M, Debiasi G, Capotosti A, Ciceri T, Carson RE, DeLorenzo C, Hahn A, Knudsen GM, Lammertsma AA, Price JC, Sossi V, Wang G, Zanotti-Fregonara P, Bertoldo A, Veronese M. An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?. EJNMMI Res. 2023 Nov 10;13(1):97. doi: 10.1186/s13550-023-01050-w. Review. PubMed PMID: 37947880; PubMed Central PMCID: PMC10638226.

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Abi-Dargham A, Moeller SJ, Ali F, DeLorenzo C, Domschke K, Horga G, Jutla A, Kotov R, Paulus MP, Rubio JM, Sanacora G, Veenstra-VanderWeele J, Krystal JH. Candidate biomarkers in psychiatric disorders: state of the field. World Psychiatry. 2023 Jun;22(2):236-262. doi: 10.1002/wps.21078. PubMed PMID: 37159365; PubMed Central PMCID: PMC10168176.

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Ali FZ, Parsey RV, Lin S, Schwartz J, DeLorenzo C. Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response. NPJ Digit Med. 2023 Apr 29;6(1):81. doi: 10.1038/s41746-023-00827-6. PubMed PMID: 37120493; PubMed Central PMCID: PMC10148831.

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Bartlett EA, Yttredahl AA, Boldrini M, Tyrer AE, Hill KR, Ananth MR, Milak MS, Oquendo MA, Mann JJ, DeLorenzo C, Parsey RV. In vivo serotonin 1A receptor hippocampal binding potential in depression and reported childhood adversity. Eur Psychiatry. 2023 Jan 24;66(1):e17. doi: 10.1192/j.eurpsy.2023.4. PubMed PMID: 36691786; PubMed Central PMCID: PMC9970152.

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Ali FZ, Wengler K, He X, Nguyen MH, Parsey RV, DeLorenzo C. Gradient boosting decision-tree-based algorithm with neuroimaging for personalized treatment in depression. Neurosci Inform. 2022 Dec;2(4). doi: 10.1016/j.neuri.2022.100110. Epub 2022 Nov 11. PubMed PMID: 36699194; PubMed Central PMCID: PMC9873411.

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Jones JS, Goldstein SJ, Wang J, Gardus J, Yang J, Parsey RV, DeLorenzo C. Evaluation of brain structure and metabolism in currently depressed adults with a history of childhood trauma. Transl Psychiatry. 2022 Sep 17;12(1):392. doi: 10.1038/s41398-022-02153-z. PubMed PMID: 36115855; PubMed Central PMCID: PMC9482635.

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Narayan GA, Hill KR, Wengler K, He X, Wang J, Yang J, Parsey RV, DeLorenzo C. Does the change in glutamate to GABA ratio correlate with change in depression severity? A randomized, double-blind clinical trial. Mol Psychiatry. 2022 Sep;27(9):3833-3841. doi: 10.1038/s41380-022-01730-4. Epub 2022 Aug 18. PubMed PMID: 35982258; PubMed Central PMCID: PMC9712215.

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Yousefzadehfard Y, Wechsler B, DeLorenzo C. Human circadian rhythm studies: Practical guidelines for inclusion/exclusion criteria and protocol. Neurobiol Sleep Circadian Rhythms. 2022 Nov;13:100080. doi: 10.1016/j.nbscr.2022.100080. eCollection 2022 Nov. Review. PubMed PMID: 35989718; PubMed Central PMCID: PMC9382328.

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Hill KR, Hsu DT, Taylor SF, Ogden RT, Parsey RV, DeLorenzo C. Mu Opioid Receptor Dynamics in Healthy Volunteers with a History of Childhood Maltreatment. J Child Adolesc Trauma. 2022 Dec;15(4):1105-1112. doi: 10.1007/s40653-022-00463-4. eCollection 2022 Dec. PubMed PMID: 36439668; PubMed Central PMCID: PMC9684394.

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Hill KR, Hsu DT, Taylor SF, Ogden RT, DeLorenzo C, Parsey RV. Rejection sensitivity and mu opioid receptor dynamics associated with mood alterations in response to social feedback. Psychiatry Res Neuroimaging. 2022 Aug;324:111505. doi: 10.1016/j.pscychresns.2022.111505. Epub 2022 Jun 6. PubMed PMID: 35688046; PubMed Central PMCID: PMC9338686.

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Kokkosis AG, Madeira MM, Mullahy MR, Tsirka SE. Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex hypomyelination. Mol Psychiatry. 2022 Jun;27(6):2833-2848. doi: 10.1038/s41380-022-01512-y. Epub 2022 Mar 17. PubMed PMID: 35301426; PubMed Central PMCID: PMC9169792.

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Koss J, DeLorenzo C, Tagare HD. Hierarchical MAP Denoising of Longitudinal Hamilton Depression Rating Scores. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2021 Dec;2021:1389-1394. doi: 10.1109/bibm52615.2021.9669362. PubMed PMID: 35419210; PubMed Central PMCID: PMC9004678.

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Hill KR, Gardus JD, Bartlett EA, Perlman G, Parsey RV, DeLorenzo C. Measuring brain glucose metabolism in order to predict response to antidepressant or placebo: A randomized clinical trial. Neuroimage Clin. 2021;32:102858. doi: 10.1016/j.nicl.2021.102858. Epub 2021 Oct 19. PubMed PMID: 34689056; PubMed Central PMCID: PMC8551925.

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Wei S, Joshi N, Salerno M, Ouellette D, Saleh L, DeLorenzo C, Woody C, Schlyer D, Purschke ML, Pratte JF, Junnarkar S, Budassi M, Cao T, Fried J, Karp JS, Vaska P. PET Imaging of Leg Arteries for Determining the Input Function in PET/MRI Brain Studies Using a Compact, MRI-compatible PET System. IEEE Trans Radiat Plasma Med Sci. 2022 May;6(5):583-591. doi: 10.1109/trpms.2021.3111841. Epub 2021 Sep 13. PubMed PMID: 36212108; PubMed Central PMCID: PMC9541963.

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Deri Y, Clouston SAP, DeLorenzo C, Gardus JD 3rd, Bartlett EA, Santiago-Michels S, Bangiyev L, Kreisl WC, Kotov R, Huang C, Slifstein M, Parsey RV, Luft BJ. Neuroinflammation in World Trade Center responders at midlife: A pilot study using [(18)F]-FEPPA PET imaging. Brain Behav Immun Health. 2021 Oct;16:100287. doi: 10.1016/j.bbih.2021.100287. eCollection 2021 Oct. PubMed PMID: 34589784; PubMed Central PMCID: PMC8474562.

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Deri Y, Clouston SAP, DeLorenzo C, Gardus JD 3rd, Horton M, Tang C, Pellecchia AC, Santiago-Michels S, Carr MA, Gandy S, Sano M, Bromet EJ, Lucchini RG, Luft BJ. Selective hippocampal subfield volume reductions in World Trade Center responders with cognitive impairment. Alzheimers Dement (Amst). 2021;13(1):e12165. doi: 10.1002/dad2.12165. eCollection 2021. PubMed PMID: 33816755; PubMed Central PMCID: PMC8011041.

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Caponegro MD, Oh K, Madeira MM, Radin D, Sterge N, Tayyab M, Moffitt RA, Tsirka SE. A distinct microglial subset at the tumor-stroma interface of glioma. Glia. 2021 Jul;69(7):1767-1781. doi: 10.1002/glia.23991. Epub 2021 Mar 11. PubMed PMID: 33704822; PubMed Central PMCID: PMC8113099.

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Jin J, Delaparte L, Chen HW, DeLorenzo C, Perlman G, Klein DN, Mohanty A, Kotov R. Structural Connectivity Between Rostral Anterior Cingulate Cortex and Amygdala Predicts First Onset of Depressive Disorders in Adolescence. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Mar;7(3):249-255. doi: 10.1016/j.bpsc.2021.01.012. Epub 2021 Feb 19. PubMed PMID: 33610811.

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Serrano-Sosa M, Sampathgiri K, Spuhler KD, DeLorenzo C, Parsey R, Huang C. The importance of identifying functional Val158Met polymorphism in catechol-O- Methyltransferase when assessing MRI-based volumetric measurements in major depressive disorder. Brain Imaging Behav. 2020 Dec;14(6):2762-2770. doi: 10.1007/s11682-019-00225-1. PubMed PMID: 31898087.

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Kim DJ, Bartlett EA, DeLorenzo C, Parsey RV, Kilts C, Cáceda R. Examination of structural brain changes in recent suicidal behavior. Psychiatry Res Neuroimaging. 2021 Jan 30;307:111216. doi: 10.1016/j.pscychresns.2020.111216. Epub 2020 Oct 24. PubMed PMID: 33129637; PubMed Central PMCID: PMC9227957.

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Spuhler K, Serrano-Sosa M, Cattell R, DeLorenzo C, Huang C. Full-count PET recovery from low-count image using a dilated convolutional neural network. Med Phys. 2020 Oct;47(10):4928-4938. doi: 10.1002/mp.14402. Epub 2020 Aug 6. PubMed PMID: 32687608.

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Clouston SAP, Deri Y, Horton M, Tang C, Diminich E, DeLorenzo C, Kritikos M, Pellecchia AC, Santiago-Michels S, Carr MA, Gandy S, Sano M, Bromet EJ, Lucchini RG, Luft BJ. Reduced cortical thickness in World Trade Center responders with cognitive impairment. Alzheimers Dement (Amst). 2020;12(1):e12059. doi: 10.1002/dad2.12059. eCollection 2020. PubMed PMID: 32695871; PubMed Central PMCID: PMC7364857.

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Pillai RLI, Bartlett EA, Ananth MR, Zhu C, Yang J, Hajcak G, Parsey RV, DeLorenzo C. Examining the underpinnings of loudness dependence of auditory evoked potentials with positron emission tomography. Neuroimage. 2020 Jun;213:116733. doi: 10.1016/j.neuroimage.2020.116733. Epub 2020 Mar 10. PubMed PMID: 32169543; PubMed Central PMCID: PMC7254571.

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Ananth M, Bartlett EA, DeLorenzo C, Lin X, Kunkel L, Vadhan NP, Perlman G, Godstrey M, Holzmacher D, Ogden RT, Parsey RV, Huang C. Prediction of lithium treatment response in bipolar depression using 5-HTT and 5-HT(1A) PET. Eur J Nucl Med Mol Imaging. 2020 Sep;47(10):2417-2428. doi: 10.1007/s00259-020-04681-6. Epub 2020 Feb 13. PubMed PMID: 32055965; PubMed Central PMCID: PMC8789023.

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Prabhakaran J, DeLorenzo C, Zanderigo F, Knudsen GM, Gilling N, Pratap M, Jorgensen MJ, Daunais J, Kaplan JR, Parsey RV, Mann JJ, Kumar D. In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates. J Pharm Pharm Sci. 2019;22(1):352-364. doi: 10.18433/jpps30329. PubMed PMID: 31356761; PubMed Central PMCID: PMC7453972.

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Bartlett EA, Ananth M, Rossano S, Zhang M, Yang J, Lin SF, Nabulsi N, Huang Y, Zanderigo F, Parsey RV, DeLorenzo C. Quantification of Positron Emission Tomography Data Using Simultaneous Estimation of the Input Function: Validation with Venous Blood and Replication of Clinical Studies. Mol Imaging Biol. 2019 Oct;21(5):926-934. doi: 10.1007/s11307-018-1300-1. PubMed PMID: 30535672; PubMed Central PMCID: PMC6555699.

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Pillai RLI, Huang C, LaBella A, Zhang M, Yang J, Trivedi M, Weissman M, McGrath P, Fava M, Kurian B, Cooper C, McInnis M, Oquendo MA, Pizzagalli DA, Parsey RV, DeLorenzo C. Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response. J Affect Disord. 2019 Sep 1;256:8-16. doi: 10.1016/j.jad.2019.05.055. Epub 2019 May 28. PubMed PMID: 31158720; PubMed Central PMCID: PMC6750958.

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Bartlett EA, Klein DN, Li K, DeLorenzo C, Kotov R, Perlman G. Depression Severity Over 27 Months in Adolescent Girls Is Predicted by Stress-Linked Cortical Morphology. Biol Psychiatry. 2019 Nov 15;86(10):769-778. doi: 10.1016/j.biopsych.2019.04.027. Epub 2019 May 7. PubMed PMID: 31230728; PubMed Central PMCID: PMC6814528.

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Delaparte L, Bartlett E, Grazioplene R, Perlman G, Gardus J, DeLorenzo C, Klein DN, Kotov R. Structural correlates of the orbitofrontal cortex and amygdala and personality in female adolescents. Psychophysiology. 2019 Aug;56(8):e13376. doi: 10.1111/psyp.13376. Epub 2019 Apr 3. PubMed PMID: 30942481; PubMed Central PMCID: PMC6650330.

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Bartlett E, Shaw M, Schwarz C, Feinberg C, DeLorenzo C, Krupp LB, Charvet LE. Brief Computer-Based Information Processing Measures are Linked to White Matter Integrity in Pediatric-Onset Multiple Sclerosis. J Neuroimaging. 2019 Jan;29(1):140-150. doi: 10.1111/jon.12566. Epub 2018 Oct 4. PubMed PMID: 30285300; PubMed Central PMCID: PMC11756925.

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Spuhler KD, Gardus J 3rd, Gao Y, DeLorenzo C, Parsey R, Huang C. Synthesis of Patient-Specific Transmission Data for PET Attenuation Correction for PET/MRI Neuroimaging Using a Convolutional Neural Network. J Nucl Med. 2019 Apr;60(4):555-560. doi: 10.2967/jnumed.118.214320. Epub 2018 Aug 30. PubMed PMID: 30166355.

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Yang J, Zhang M, Ahn H, Zhang Q, Jin TB, Li I, Nemesure M, Joshi N, Jiang H, Miller JM, Ogden RT, Petkova E, Milak MS, Sublette ME, Sullivan GM, Trivedi MH, Weissman M, McGrath PJ, Fava M, Kurian BT, Pizzagalli DA, Cooper CM, McInnis M, Oquendo MA, Mann JJ, Parsey RV, DeLorenzo C. Development and evaluation of a multimodal marker of major depressive disorder. Hum Brain Mapp. 2018 Nov;39(11):4420-4439. doi: 10.1002/hbm.24282. Epub 2018 Aug 16. PubMed PMID: 30113112; PubMed Central PMCID: PMC6815672.

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Kumar JSD, Bai B, Zanderigo F, DeLorenzo C, Prabhakaran J, Parsey RV, Mann JJ. In Vivo Brain Imaging, Biodistribution, and Radiation Dosimetry Estimation of [(11)C]Celecoxib, a COX-2 PET Ligand, in Nonhuman Primates. Molecules. 2018 Aug 2;23(8). doi: 10.3390/molecules23081929. PubMed PMID: 30072617; PubMed Central PMCID: PMC6222548.

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Zanderigo F, D'Agostino AE, Joshi N, Schain M, Kumar D, Parsey RV, DeLorenzo C, Mann JJ. [(11)C]Harmine Binding to Brain Monoamine Oxidase A: Test-Retest Properties and Noninvasive Quantification. Mol Imaging Biol. 2018 Aug;20(4):667-681. doi: 10.1007/s11307-018-1165-3. PubMed PMID: 29423903.

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Miller JM, Zanderigo F, Purushothaman PD, DeLorenzo C, Rubin-Falcone H, Ogden RT, Keilp J, Oquendo MA, Nabulsi N, Huang YH, Parsey RV, Carson RE, Mann JJ. Kappa opioid receptor binding in major depression: A pilot study. Synapse. 2018 Sep;72(9):e22042. doi: 10.1002/syn.22042. Epub 2018 Jul 17. PubMed PMID: 29935119; PubMed Central PMCID: PMC7599086.

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Bartlett EA, DeLorenzo C, Sharma P, Yang J, Zhang M, Petkova E, Weissman M, McGrath PJ, Fava M, Ogden RT, Kurian BT, Malchow A, Cooper CM, Trombello JM, McInnis M, Adams P, Oquendo MA, Pizzagalli DA, Trivedi M, Parsey RV. Pretreatment and early-treatment cortical thickness is associated with SSRI treatment response in major depressive disorder. Neuropsychopharmacology. 2018 Oct;43(11):2221-2230. doi: 10.1038/s41386-018-0122-9. Epub 2018 Jun 19. PubMed PMID: 29955151; PubMed Central PMCID: PMC6135779.

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Milak MS, Pantazatos S, Rashid R, Zanderigo F, DeLorenzo C, Hesselgrave N, Ogden RT, Oquendo MA, Mulhern ST, Miller JM, Burke AK, Parsey RV, Mann JJ. Higher 5-HT(1A) autoreceptor binding as an endophenotype for major depressive disorder identified in high risk offspring - A pilot study. Psychiatry Res Neuroimaging. 2018 Jun 30;276:15-23. doi: 10.1016/j.pscychresns.2018.04.002. Epub 2018 Apr 13. PubMed PMID: 29702461; PubMed Central PMCID: PMC5959803.

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Pillai RL, Zhang M, Yang J, Mann JJ, Oquendo MA, Parsey RV, DeLorenzo C. Molecular connectivity disruptions in males with major depressive disorder. J Cereb Blood Flow Metab. 2019 Aug;39(8):1623-1634. doi: 10.1177/0271678X18764053. Epub 2018 Mar 9. PubMed PMID: 29519187; PubMed Central PMCID: PMC6681531.

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Pillai RLI, Zhang M, Yang J, Boldrini M, Mann JJ, Oquendo MA, Parsey RV, DeLorenzo C. Will imaging individual raphe nuclei in males with major depressive disorder enhance diagnostic sensitivity and specificity?. Depress Anxiety. 2018 May;35(5):411-420. doi: 10.1002/da.22721. Epub 2018 Jan 24. PubMed PMID: 29365217; PubMed Central PMCID: PMC5934332.

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Huang, Chuan, Spuhler, Karl, DeLorenzo, Christine, Parsey, Ramin. A pilot PET/MR study of hippocampal, diffusivity and brain metabolism changes following electroconvulsive therapy. Journal of Nuclear Medicine. 2017; 58.

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Joshi, N., Mikhno, A., DeLorenzo, C., Parsey, R. V.. Improved Major Depressive Disorder (MDD) biomarker performance with a novel image reconstruction approach. Journal of Cerebral Blood Flow and Metabolism. 2017; 37:143.