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Seshadri C, Uiso LO, Ostermann J, Diefenthal H, Shao HJ, Chu HY, Asmuth DM, Thielman NM, Bartlett JA, Crump JA. Low sensitivity of T-cell based detection of tuberculosis among HIV co-infected Tanzanian in-patients. East Afr Med J. 2008 Sep;85(9):442-9. doi: 10.4314/eamj.v85i9.117085. PubMed PMID: 19537417; PubMed Central PMCID: PMC3168735.
Ter Horst B, Seshadri C, Sweet L, Young DC, Feringa BL, Moody DB, Minnaard AJ. Asymmetric synthesis and structure elucidation of a glycerophospholipid from Mycobacterium tuberculosis. J Lipid Res. 2010 May;51(5):1017-22. doi: 10.1194/jlr.M001982. Epub 2009 Nov 5. PubMed PMID: 19965610; PubMed Central PMCID: PMC2853428.
Drage MG, Tsai HC, Pecora ND, Cheng TY, Arida AR, Shukla S, Rojas RE, Seshadri C, Moody DB, Boom WH, Sacchettini JC, Harding CV. Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat Struct Mol Biol. 2010 Sep;17(9):1088-95. doi: 10.1038/nsmb.1869. Epub 2010 Aug 8. PubMed PMID: 20694006; PubMed Central PMCID: PMC2933325.
Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29;208(9):1741-7. doi: 10.1084/jem.20110665. Epub 2011 Aug 1. PubMed PMID: 21807869; PubMed Central PMCID: PMC3171094.
Seshadri C, Turner MT, Lewinsohn DM, Moody DB, Van Rhijn I. Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. J Immunol. 2013 Jan 1;190(1):278-84. doi: 10.4049/jimmunol.1201667. Epub 2012 Nov 28. PubMed PMID: 23197260; PubMed Central PMCID: PMC3529834.
Seshadri C, Shenoy M, Wells RD, Hensley-McBain T, Andersen-Nissen E, McElrath MJ, Cheng TY, Moody DB, Hawn TR. Human CD1a deficiency is common and genetically regulated. J Immunol. 2013 Aug 15;191(4):1586-93. doi: 10.4049/jimmunol.1300575. Epub 2013 Jul 15. PubMed PMID: 23858036; PubMed Central PMCID: PMC3748949.
Seshadri C, Thuong NT, Yen NT, Bang ND, Chau TT, Thwaites GE, Dunstan SJ, Hawn TR. A polymorphism in human CD1A is associated with susceptibility to tuberculosis. Genes Immun. 2014 Apr-May;15(3):195-8. doi: 10.1038/gene.2014.5. Epub 2014 Feb 6. PubMed PMID: 24500401; PubMed Central PMCID: PMC3998877.
Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, Moody DB. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chem Biol. 2015 Apr 23;22(4):516-526. doi: 10.1016/j.chembiol.2015.03.015. PubMed PMID: 25910243; PubMed Central PMCID: PMC4432472.
Lin L, Finak G, Ushey K, Seshadri C, Hawn TR, Frahm N, Scriba TJ, Mahomed H, Hanekom W, Bart PA, Pantaleo G, Tomaras GD, Rerks-Ngarm S, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Michael NL, Kim JH, Robb ML, O'Connell RJ, Karasavvas N, Gilbert P, C De Rosa S, McElrath MJ, Gottardo R. COMPASS identifies T-cell subsets correlated with clinical outcomes. Nat Biotechnol. 2015 Jun;33(6):610-6. doi: 10.1038/nbt.3187. Epub 2015 May 25. PubMed PMID: 26006008; PubMed Central PMCID: PMC4569006.
Lin L, Frelinger J, Jiang W, Finak G, Seshadri C, Bart PA, Pantaleo G, McElrath J, DeRosa S, Gottardo R. Identification and visualization of multidimensional antigen-specific T-cell populations in polychromatic cytometry data. Cytometry A. 2015 Jul;87(7):675-82. doi: 10.1002/cyto.a.22623. Epub 2015 Apr 23. PubMed PMID: 25908275; PubMed Central PMCID: PMC4482785.
Seshadri C, Lin L, Scriba TJ, Peterson G, Freidrich D, Frahm N, DeRosa SC, Moody DB, Prandi J, Gilleron M, Mahomed H, Jiang W, Finak G, Hanekom WA, Gottardo R, McElrath MJ, Hawn TR. T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents. J Immunol. 2015 Nov 15;195(10):4595-603. doi: 10.4049/jimmunol.1501285. Epub 2015 Oct 14. PubMed PMID: 26466957; PubMed Central PMCID: PMC4637215.
Seshadri C, Thuong NT, Mai NT, Bang ND, Chau TT, Lewinsohn DM, Thwaites GE, Dunstan SJ, Hawn TR. A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis. Genes Immun. 2017 Jan;18(1):8-14. doi: 10.1038/gene.2016.41. Epub 2016 Nov 24. PubMed PMID: 27881839; PubMed Central PMCID: PMC5269436.
Seshadri C, Sedaghat N, Campo M, Peterson G, Wells RD, Olson GS, Sherman DR, Stein CM, Mayanja-Kizza H, Shojaie A, Boom WH, Hawn TR. Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection. PLoS One. 2017;12(4):e0175844. doi: 10.1371/journal.pone.0175844. eCollection 2017. PubMed PMID: 28414762; PubMed Central PMCID: PMC5393882.
James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I. CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis. Cell Chem Biol. 2018 Apr 19;25(4):392-402.e14. doi: 10.1016/j.chembiol.2018.01.006. Epub 2018 Feb 1. PubMed PMID: 29398561; PubMed Central PMCID: PMC5910231.
Layton ED, Yu KKQ, Smith MT, Scriba TJ, De Rosa SC, Seshadri C. Validation of a CD1b tetramer assay for studies of human mycobacterial infection or vaccination. J Immunol Methods. 2018 Jul;458:44-52. doi: 10.1016/j.jim.2018.04.004. Epub 2018 Apr 21. PubMed PMID: 29684428; PubMed Central PMCID: PMC5960426.
DeWitt WS, Yu KKQ, Wilburn DB, Sherwood A, Vignali M, Day CL, Scriba TJ, Robins HS, Swanson WJ, Emerson RO, Bradley PH, Seshadri C. A Diverse Lipid Antigen-Specific TCR Repertoire Is Clonally Expanded during Active Tuberculosis. J Immunol. 2018 Aug 1;201(3):888-896. doi: 10.4049/jimmunol.1800186. Epub 2018 Jun 18. PubMed PMID: 29914888; PubMed Central PMCID: PMC6057832.
Simmons JD, Stein CM, Seshadri C, Campo M, Alter G, Fortune S, Schurr E, Wallis RS, Churchyard G, Mayanja-Kizza H, Boom WH, Hawn TR. Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection. Nat Rev Immunol. 2018 Sep;18(9):575-589. doi: 10.1038/s41577-018-0025-3. Review. PubMed PMID: 29895826; PubMed Central PMCID: PMC6278832.
Graustein AD, Misch EA, Musvosvi M, Shey M, Shah JA, Seshadri C, Ajuogu A, Bowman K, Mulenga H, Veldsman A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria. PLoS One. 2018;13(12):e0208940. doi: 10.1371/journal.pone.0208940. eCollection 2018. PubMed PMID: 30550567; PubMed Central PMCID: PMC6294361.
Joosten SA, Ottenhoff THM, Lewinsohn DM, Hoft DF, Moody DB, Seshadri C. Harnessing donor unrestricted T-cells for new vaccines against tuberculosis. Vaccine. 2019 May 21;37(23):3022-3030. doi: 10.1016/j.vaccine.2019.04.050. Epub 2019 Apr 27. Review. PubMed PMID: 31040086; PubMed Central PMCID: PMC6525272.
Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G. IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure. Nat Med. 2019 Jun;25(6):977-987. doi: 10.1038/s41591-019-0441-3. Epub 2019 May 20. PubMed PMID: 31110348; PubMed Central PMCID: PMC6559862.
Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G. Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure. Nat Med. 2019 Jul;25(7):1175. doi: 10.1038/s41591-019-0519-y. PubMed PMID: 31222179; PubMed Central PMCID: PMC7609258.
Yu KKQ, Wilburn DB, Hackney JA, Darrah PA, Foulds KE, James CA, Smith MT, Jing L, Seder RA, Roederer M, Koelle DM, Swanson WJ, Seshadri C. Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates. Immunogenetics. 2019 Jul;71(7):465-478. doi: 10.1007/s00251-019-01118-9. Epub 2019 May 23. PubMed PMID: 31123763; PubMed Central PMCID: PMC6647187.
Dropulic LK, Oestreich MC, Pietz HL, Laing KJ, Hunsberger S, Lumbard K, Garabedian D, Turk SP, Chen A, Hornung RL, Seshadri C, Smith MT, Hosken NA, Phogat S, Chang LJ, Koelle DM, Wang K, Cohen JI. A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection. J Infect Dis. 2019 Aug 9;220(6):990-1000. doi: 10.1093/infdis/jiz225. PubMed PMID: 31058977; PubMed Central PMCID: PMC6688060.
James CA, Seshadri C. T Cell Responses to Mycobacterial Glycolipids: On the Spectrum of "Innateness". Front Immunol. 2020;11:170. doi: 10.3389/fimmu.2020.00170. eCollection 2020. Review. PubMed PMID: 32117300; PubMed Central PMCID: PMC7026021.
Lalvani A, Seshadri C. Understanding How BCG Vaccine Protects Against Mycobacterium tuberculosis Infection: Lessons From Household Contact Studies. J Infect Dis. 2020 Mar 28;221(8):1229-1231. doi: 10.1093/infdis/jiz261. PubMed PMID: 31298279.
Berry SB, Gower MS, Su X, Seshadri C, Theberge AB. A Modular Microscale Granuloma Model for Immune-Microenvironment Signaling Studies in vitro. Front Bioeng Biotechnol. 2020;8:931. doi: 10.3389/fbioe.2020.00931. eCollection 2020. PubMed PMID: 32974300; PubMed Central PMCID: PMC7461927.
Yu KKQ, Fischinger S, Smith MT, Atyeo C, Cizmeci D, Wolf CR, Layton ED, Logue JK, Aguilar MS, Shuey K, Loos C, Yu J, Franko N, Choi RY, Wald A, Barouch DH, Koelle DM, Lauffenburger D, Chu HY, Alter G, Seshadri C. T cell and antibody functional correlates of severe COVID-19. medRxiv. 2020 Nov 30;. doi: 10.1101/2020.11.25.20235150. PubMed PMID: 33269369; PubMed Central PMCID: PMC7709190.
Layton ED, Barman S, Wilburn DB, Yu KKQ, Smith MT, Altman JD, Scriba TJ, Tahiri N, Minnaard AJ, Roederer M, Seder RA, Darrah PA, Seshadri C. T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette-Guérin Vaccination. J Immunol. 2021 Mar 15;206(6):1240-1250. doi: 10.4049/jimmunol.2001065. Epub 2021 Feb 3. PubMed PMID: 33536255; PubMed Central PMCID: PMC7939042.
Yu KK, Fischinger S, Smith MT, Atyeo C, Cizmeci D, Wolf CR, Layton ED, Logue JK, Aguilar MS, Shuey K, Loos C, Yu J, Franko N, Choi RY, Wald A, Barouch DH, Koelle DM, Lauffenburger D, Chu HY, Alter G, Seshadri C. Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2. JCI Insight. 2021 Mar 22;6(6). doi: 10.1172/jci.insight.146242. PubMed PMID: 33621211; PubMed Central PMCID: PMC8026190.
Simmons JD, Van PT, Stein CM, Chihota V, Ntshiqa T, Maenetje P, Peterson GJ, Reynolds A, Benchek P, Velen K, Fielding KL, Grant AD, Graustein AD, Nguyen FK, Seshadri C, Gottardo R, Mayanja-Kizza H, Wallis RS, Churchyard G, Boom WH, Hawn TR. Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-γ release assay conversion. J Clin Invest. 2021 Jul 15;131(14). doi: 10.1172/JCI140073. PubMed PMID: 34111032; PubMed Central PMCID: PMC8279582.
Zhou AX, Scriba TJ, Day CL, Hagge DA, Seshadri C. A simple assay to quantify mycobacterial lipid antigen-specific T cell receptors in human tissues and blood. PLoS Negl Trop Dis. 2021 Dec;15(12):e0010018. doi: 10.1371/journal.pntd.0010018. eCollection 2021 Dec. PubMed PMID: 34914694; PubMed Central PMCID: PMC8717985.
Seshadri C, Sutherland JS, Lindestam Arlehamn CS, Burel JG. Editorial: Exploring Immune Variability in Susceptibility to Tuberculosis Infection in Humans. Front Immunol. 2021;12:830920. doi: 10.3389/fimmu.2021.830920. eCollection 2021. PubMed PMID: 35069606; PubMed Central PMCID: PMC8777100.
James CA, Xu Y, Aguilar MS, Jing L, Layton ED, Gilleron M, Minnaard AJ, Scriba TJ, Day CL, Warren EH, Koelle DM, Seshadri C. CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells. Nat Commun. 2022 Jan 10;13(1):78. doi: 10.1038/s41467-021-27764-w. PubMed PMID: 35013257; PubMed Central PMCID: PMC8748927.
Gela A, Murphy M, Rodo M, Hadley K, Hanekom WA, Boom WH, Johnson JL, Hoft DF, Joosten SA, Ottenhoff THM, Suliman S, Moody DB, Lewinsohn DM, Hatherill M, Seshadri C, Nemes E, Scriba TJ, Briel L, Veldtsman H, Khomba N, Pienaar B, Africa H, Steyn M. Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies. EBioMedicine. 2022 Feb;76:103839. doi: 10.1016/j.ebiom.2022.103839. Epub 2022 Feb 8. PubMed PMID: 35149285; PubMed Central PMCID: PMC8842032.
James CA, Yu KKQ, Mayer-Blackwell K, Fiore-Gartland A, Smith MT, Layton ED, Johnson JL, Hanekom WA, Scriba TJ, Seshadri C. Durable Expansion of TCR-δ Meta-Clonotypes After BCG Revaccination in Humans. Front Immunol. 2022;13:834757. doi: 10.3389/fimmu.2022.834757. eCollection 2022. PubMed PMID: 35432299; PubMed Central PMCID: PMC9005636.
Corcorran MA, Stewart J, Lan K, Gupta A, Glick SN, Seshadri C, Koomalsingh KJ, Gibbons EF, Harrington RD, Dhanireddy S, Kim HN. Correlates of 90-Day Mortality Among People Who Do and Do Not Inject Drugs With Infective Endocarditis in Seattle, Washington. Open Forum Infect Dis. 2022 May;9(5):ofac150. doi: 10.1093/ofid/ofac150. eCollection 2022 May. PubMed PMID: 35493129; PubMed Central PMCID: PMC9045945.
Dawkins BA, Garman L, Cejda N, Pezant N, Rasmussen A, Rybicki BA, Levin AM, Benchek P, Seshadri C, Mayanja-Kizza H, Iannuzzi MC, Stein CM, Montgomery CG. Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest-neighbor feature selection. Genet Epidemiol. 2022 Oct;46(7):463-474. doi: 10.1002/gepi.22490. Epub 2022 Jun 14. PubMed PMID: 35702824; PubMed Central PMCID: PMC10237150.
Phan JM, Layton ED, Yu KKQ, Aguilar MS, Golez I, Franko NM, Logue JK, Rodda LB, Howard CA, Pepper M, Gale M Jr, Chu HY, Seshadri C. Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with Hybrid Immunity to SARS-CoV-2. J Immunol. 2023 May 1;210(9):1236-1246. doi: 10.4049/jimmunol.2200815. PubMed PMID: 36961450; PubMed Central PMCID: PMC10121904.
Davies LRL, Smith MT, Cizmeci D, Fischinger S, Shih-Lu Lee J, Lu LL, Layton ED, Grant AD, Fielding K, Stein CM, Boom WH, Hawn TR, Fortune SM, Wallis RS, Churchyard GJ, Alter G, Seshadri C. IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold miners. EBioMedicine. 2023 Jul;93:104678. doi: 10.1016/j.ebiom.2023.104678. Epub 2023 Jun 26. PubMed PMID: 37379655; PubMed Central PMCID: PMC10320233.
Morgun E, Zhu J, Almunif S, Bobbala S, Aguilar MS, Wang J, Conner K, Cui Y, Cao L, Seshadri C, Scott EA, Wang CR. Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells. bioRxiv. 2023 Jul 13;. doi: 10.1101/2023.03.07.531489. PubMed PMID: 36945395; PubMed Central PMCID: PMC10028924.
Iwase SC, Edlefsen PT, Bhebhe L, Motsumi K, Moyo S, Happel AU, Shao D, Mmasa N, Schenkel S, Gasper MA, Dubois M, Files MA, Seshadri C, Duffy F, Aitchison J, Netea MG, Jao J, Cameron DW, Gray CM, Jaspan HB, Powis KM. T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure. Clin Infect Dis. 2023 Oct 13;77(8):1133-1136. doi: 10.1093/cid/ciad356. PubMed PMID: 37293702; PubMed Central PMCID: PMC10573724.
Morgun E, Zhu J, Almunif S, Bobbala S, Aguilar MS, Wang J, Conner K, Cui Y, Cao L, Seshadri C, Scott EA, Wang CR. Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells. Elife. 2023 Oct 25;12. doi: 10.7554/eLife.87431. PubMed PMID: 37877801; PubMed Central PMCID: PMC10599656.
Chang M, Venkatasubramanian S, Barrett H, Urdahl KB, Weigel KM, Cangelosi GA, Shah JA, Saha A, Feng L, Adams KN, Sherman DR, Smith N, Seshadri C, Kublin JG, Murphy SC. Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development. Diagn Microbiol Infect Dis. 2024 Jan;108(1):116106. doi: 10.1016/j.diagmicrobio.2023.116106. Epub 2023 Oct 16. PubMed PMID: 37931386; PubMed Central PMCID: PMC10729053.
Cross DL, Layton ED, Yu KK, Smith MT, Aguilar MS, Li S, Wilcox EC, Chapuis AG, Mayanja-Kizza H, Stein CM, Boom WH, Hawn TR, Bradley P, Newell EW, Seshadri C. MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection. JCI Insight. 2024 May 8;9(9). doi: 10.1172/jci.insight.166505. PubMed PMID: 38716731; PubMed Central PMCID: PMC11141901.
Maerz MD, Cross DL, Seshadri C. Functional and biological implications of clonotypic diversity among human donor-unrestricted T cells. Immunol Cell Biol. 2024 Jul;102(6):474-486. doi: 10.1111/imcb.12751. Epub 2024 Apr 24. Review. PubMed PMID: 38659280; PubMed Central PMCID: PMC11236517.
Sun M, Phan JM, Kieswetter NS, Huang H, Yu KKQ, Smith MT, Liu YE, Wang C, Gupta S, Obermoser G, Maecker HT, Krishnan A, Suresh S, Gupta N, Rieck M, Acs P, Ghanizada M, Chiou SH, Khatri P, Boom WH, Hawn TR, Stein CM, Mayanja-Kizza H, Davis MM, Seshadri C. Specific CD4(+) T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nat Immunol. 2024 Aug;25(8):1411-1421. doi: 10.1038/s41590-024-01897-8. Epub 2024 Jul 12. PubMed PMID: 38997431; PubMed Central PMCID: PMC11291275.
Church EC, Bishop E, Fiore-Gartland A, Yu KKQ, Chang M, Jones RM, Brache JK, Ballweber Fleming L, Phan JM, Makatsa MS, Heptinstall J, Chiong K, Dintwe O, Naidoo A, Voillet V, Mayer-Blackwell K, Nwanne G, Andersen-Nissen E, Vary JC Jr, Tomaras GD, McElrath MJ, Sherman DR, Murphy SC, Kublin JG, Seshadri C. Probing Dermal Immunity to Mycobacteria through a Controlled Human Infection Model. Immunohorizons. 2024 Sep 1;8(9):695-711. doi: 10.4049/immunohorizons.2400053. PubMed PMID: 39283647; PubMed Central PMCID: PMC11447685.
Files MA, Gentles L, Kehoe L, Adler A, Lacombe K, Dickerson JA, Greninger A, Waghmare A, Fairlie T, Pringle K, Midgley CM, Hagen MB, Englund JA, Seshadri C. Kinetics and Durability of Antibody and T-Cell Responses to SARS-CoV-2 in Children. J Infect Dis. 2024 Oct 16;230(4):889-900. doi: 10.1093/infdis/jiae301. PubMed PMID: 38838218; PubMed Central PMCID: PMC11481334.
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