Jagged: a mammalian ligand that activates Notch1.
Cell.
1995 Mar 24;80(6):909-17. doi: 10.1016/0092-8674(95)90294-5. PubMed PMID:
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Jagged2: a serrate-like gene expressed during rat embryogenesis.
Dev Biol.
1996 Nov 25;180(1):370-6. doi: 10.1006/dbio.1996.0310. PubMed PMID:
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Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway.
Development.
1996 Dec;122(12):3765-73. doi: 10.1242/dev.122.12.3765. PubMed PMID:
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The Jagged2 gene maps to chromosome 12 and is a candidate for the lgl and sm mutations.
Mamm Genome.
1997;8(11):875-6. doi: 10.1007/s003359900642. PubMed PMID:
9341252.
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice.
Genes Dev.
1998 Apr 1;12(7):1046-57. doi: 10.1101/gad.12.7.1046. PubMed PMID:
9531541; PubMed Central PMCID:
PMC316673.
CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand.
Circ Res.
2002 Mar 22;90(5):506-8. doi: 10.1161/01.res.0000013796.73742.c8. PubMed PMID:
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PMC3690627.
Notch signaling in primary endothelial cells.
Ann N Y Acad Sci.
2003 May;995:162-70. doi: 10.1111/j.1749-6632.2003.tb03219.x. PubMed PMID:
12814948.
Notch function in the vasculature: insights from zebrafish, mouse and man.
Bioessays.
2004 Mar;26(3):225-34. doi: 10.1002/bies.20004. Review. PubMed PMID:
14988924.
Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells.
Angiogenesis.
2005;8(1):43-51. doi: 10.1007/s10456-005-5612-9. PubMed PMID:
16132617.
Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.
Gene Expr Patterns.
2005 Jun;5(5):701-9. doi: 10.1016/j.modgep.2005.02.001. Epub 2005 Apr 13. PubMed PMID:
15939383.
Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Genome Res.
2006 Feb;16(2):282-9. doi: 10.1101/gr.4181406. Epub 2005 Dec 20. PubMed PMID:
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PMC1361724.
Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling.
Cancer Res.
2006 Apr 15;66(8):4378-84. doi: 10.1158/0008-5472.CAN-05-3810. PubMed PMID:
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A Foxo/Notch pathway controls myogenic differentiation and fiber type specification.
J Clin Invest.
2007 Sep;117(9):2477-85. doi: 10.1172/JCI32054. PubMed PMID:
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PMC1950461.
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
J Clin Invest.
2007 Nov;117(11):3369-82. doi: 10.1172/JCI24311. PubMed PMID:
17948123; PubMed Central PMCID:
PMC2030453.
Arterial regulators taken up by lymphatics.
Lymphat Res Biol.
2008;6(3-4):139-43. doi: 10.1089/lrb.2008.1024. Review. PubMed PMID:
19093785; PubMed Central PMCID:
PMC2940254.
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis.
Cancer Res.
2008 Jun 15;68(12):4727-35. doi: 10.1158/0008-5472.CAN-07-6499. PubMed PMID:
18559519; PubMed Central PMCID:
PMC3690602.
Notch regulates the angiogenic response via induction of VEGFR-1.
J Angiogenes Res.
2010 Jan 26;2(1):3. doi: 10.1186/2040-2384-2-3. PubMed PMID:
20298529; PubMed Central PMCID:
PMC2828996.
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Cell Stem Cell.
2010 Mar 5;6(3):251-64. doi: 10.1016/j.stem.2010.02.001. PubMed PMID:
20207228; PubMed Central PMCID:
PMC2866527.
Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7.
Blood.
2010 Dec 23;116(26):6133-43. doi: 10.1182/blood-2010-03-274860. Epub 2010 Oct 14. PubMed PMID:
20947685; PubMed Central PMCID:
PMC3031397.
Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity.
Vasc Cell.
2011 Jan 18;3(1):2. doi: 10.1186/2045-824X-3-2. PubMed PMID:
21349159; PubMed Central PMCID:
PMC3039832.
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.
Nat Med.
2011 Jul 31;17(8):961-7. doi: 10.1038/nm.2378. PubMed PMID:
21804540; PubMed Central PMCID:
PMC3387563.
Notch signaling in developmental and tumor angiogenesis.
Genes Cancer.
2011 Dec;2(12):1106-16. doi: 10.1177/1947601911423030. PubMed PMID:
22866202; PubMed Central PMCID:
PMC3411124.
Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Cancer Cell.
2012 Jan 17;21(1):36-51. doi: 10.1016/j.ccr.2011.12.004. PubMed PMID:
22264787; PubMed Central PMCID:
PMC3266546.
Propranolol accelerates adipogenesis in hemangioma stem cells and causes apoptosis of hemangioma endothelial cells.
Plast Reconstr Surg.
2012 Nov;130(5):1012-1021. doi: 10.1097/PRS.0b013e318267d3db. PubMed PMID:
23096601; PubMed Central PMCID:
PMC3668332.
The role of Notch and gamma-secretase inhibition in an ovarian cancer model.
Anticancer Res.
2013 Mar;33(3):801-8. PubMed PMID:
23482747; PubMed Central PMCID:
PMC3893696.
Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).
Reprod Biol Endocrinol.
2013 May 15;11:43. doi: 10.1186/1477-7827-11-43. PubMed PMID:
23675950; PubMed Central PMCID:
PMC3662615.
Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.
Development.
2013 Jun;140(11):2365-76. doi: 10.1242/dev.083865. Epub 2013 Apr 24. PubMed PMID:
23615281; PubMed Central PMCID:
PMC3653558.
Lymphatics in health and disease: a new thematic series in vascular cell.
Vasc Cell.
2013 Jul 25;5(1):14. doi: 10.1186/2045-824X-5-14. PubMed PMID:
23885747; PubMed Central PMCID:
PMC3734013.
NOTCH2 expression is decreased in epithelial ovarian cancer and is related to the tumor histological subtype.
Pathol Discov.
2013 Aug 16;1:4. doi: 10.7243/2052-7896-1-4. PubMed PMID:
24707357; PubMed Central PMCID:
PMC3975618.
Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis.
Vasc Cell.
2013 Sep 25;5(1):17. doi: 10.1186/2045-824X-5-17. PubMed PMID:
24066611; PubMed Central PMCID:
PMC3849070.
Hepatic notch signaling correlates with insulin resistance and nonalcoholic fatty liver disease.
Diabetes.
2013 Dec;62(12):4052-62. doi: 10.2337/db13-0769. Epub 2013 Aug 29. PubMed PMID:
23990360; PubMed Central PMCID:
PMC3837035.
Notch signaling functions in lymphatic valve formation.
Development.
2014 Jun;141(12):2446-51. doi: 10.1242/dev.101188. PubMed PMID:
24917500; PubMed Central PMCID:
PMC4050693.
VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.
Vasc Cell.
2014;6:16. doi: 10.1186/2045-824X-6-16. eCollection 2014. PubMed PMID:
25101167; PubMed Central PMCID:
PMC4122670.
Propranolol promotes accelerated and dysregulated adipogenesis in hemangioma stem cells.
Ann Plast Surg.
2014 Sep;73 Suppl 1(0 1):S119-24. doi: 10.1097/SAP.0000000000000272. PubMed PMID:
25115372; PubMed Central PMCID:
PMC4134106.
NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.
Cancer Discov.
2015 Feb;5(2):182-97. doi: 10.1158/2159-8290.CD-14-0650. Epub 2014 Nov 11. PubMed PMID:
25387766; PubMed Central PMCID:
PMC4423829.
Aberrant lymphatic endothelial progenitors in lymphatic malformation development.
PLoS One.
2015;10(2):e0117352. doi: 10.1371/journal.pone.0117352. eCollection 2015. PubMed PMID:
25719418; PubMed Central PMCID:
PMC4342011.
Notch suppresses angiogenesis and progression of hepatic metastases.
Cancer Res.
2015 Apr 15;75(8):1592-602. doi: 10.1158/0008-5472.CAN-14-1493. Epub 2015 Mar 5. PubMed PMID:
25744722; PubMed Central PMCID:
PMC4401639.
Growth Hormone Induces Recurrence of Infantile Hemangiomas After Apparent Involution: Evidence of Growth Hormone Receptors in Infantile Hemangioma.
Pediatr Dermatol.
2015 Jul-Aug;32(4):539-43. doi: 10.1111/pde.12530. Epub 2015 Feb 18. PubMed PMID:
25690955; PubMed Central PMCID:
PMC5433863.
Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus.
Vasc Cell.
2015;7:9. doi: 10.1186/s13221-015-0034-y. eCollection 2015. PubMed PMID:
26629328; PubMed Central PMCID:
PMC4666149.
Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation.
Stem Cells Transl Med.
2016 Jan;5(1):45-55. doi: 10.5966/sctm.2015-0076. Epub 2015 Nov 16. PubMed PMID:
26574555; PubMed Central PMCID:
PMC4704871.
History of the infantile hepatic hemangioma: From imaging to generating a differential diagnosis.
World J Clin Pediatr.
2016 Aug 8;5(3):273-80. doi: 10.5409/wjcp.v5.i3.273. eCollection 2016 Aug 8. Review. PubMed PMID:
27610342; PubMed Central PMCID:
PMC4978619.
Initial Experience With Propranolol Treatment of Lymphatic Anomalies: A Case Series.
Pediatrics.
2016 Sep;138(3). doi: 10.1542/peds.2015-4545. Epub 2016 Aug 25. PubMed PMID:
27561730; PubMed Central PMCID:
PMC5005016.
A new paradigm for the role of smooth muscle cells in the human cervix.
Am J Obstet Gynecol.
2016 Oct;215(4):478.e1-478.e11. doi: 10.1016/j.ajog.2016.04.053. Epub 2016 May 7. PubMed PMID:
27166013.
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.
Elife.
2017 Jun 3;6. doi: 10.7554/eLife.24265. PubMed PMID:
28577314; PubMed Central PMCID:
PMC5484618.
Dynamic maternal and fetal Notch activity and expression in placentation.
Placenta.
2017 Jul;55:5-12. doi: 10.1016/j.placenta.2017.04.014. Epub 2017 Apr 21. PubMed PMID:
28623973; PubMed Central PMCID:
PMC5754215.
Myeloid Wnt ligands are required for normal development of dermal lymphatic vasculature.
PLoS One.
2017;12(8):e0181549. doi: 10.1371/journal.pone.0181549. eCollection 2017. PubMed PMID:
28846685; PubMed Central PMCID:
PMC5573294.
NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma.
JCI Insight.
2017 Nov 2;2(21). doi: 10.1172/jci.insight.93764. PubMed PMID:
29093274; PubMed Central PMCID:
PMC5752265.
Fibrocartilage Stem Cells Engraft and Self-Organize into Vascularized Bone.
J Dent Res.
2018 Mar;97(3):329-337. doi: 10.1177/0022034517735094. Epub 2017 Oct 11. PubMed PMID:
29020504; PubMed Central PMCID:
PMC5833184.
Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia.
FASEB J.
2018 May;32(5):2574-2586. doi: 10.1096/fj.201701008R. Epub 2018 Jan 8. PubMed PMID:
29279353; PubMed Central PMCID:
PMC5901389.
Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations.
Sci Rep.
2018 Dec 20;8(1):17987. doi: 10.1038/s41598-018-36628-1. PubMed PMID:
30573741; PubMed Central PMCID:
PMC6302123.
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