My Bibliography

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Zimmermann CS, Thundivalappil SR, Wilson-Mifsud B, Boyle S, Wang Y, Lamb I, Merrell M, Mathesius CA, Fallers MN, Bultman J, Smith BL, Carlson AB, Stewart KL, Nelson M, Hurley BP. Hazard assessment of insecticidal proteins representing different structural classes using an in vitro experimental platform of human intestinal epithelial monolayers. Food Chem Toxicol. 2026 Jan;207:115850. doi: 10.1016/j.fct.2025.115850. Epub 2025 Nov 13. PubMed PMID: 41241130.

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Drenkard E, Godfrey C, Hopke A, Thundivalappil SR, Li MC, Irimia D, Hurley BP. Pseudomonas aeruginosa aggregates elicit neutrophil swarming. iScience. 2025 Feb 21;28(2):111805. doi: 10.1016/j.isci.2025.111805. eCollection 2025 Feb 21. PubMed PMID: 39967870; PubMed Central PMCID: PMC11834114.

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Philpott JD, Miller J, Boribong BP, Charles S, Davis JP, Kazimierczyk S, Jimena B, Leonard MM, Shreffler WG, Fasano A, Yonker LM, Jain N. Antigen-specific T cell responses in SARS-CoV-2 mRNA-vaccinated children. Cell Rep Med. 2023 Dec 19;4(12):101298. doi: 10.1016/j.xcrm.2023.101298. Epub 2023 Nov 27. PubMed PMID: 38016480; PubMed Central PMCID: PMC10772322.

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Zimmermann CS, Snow RF, Wilson-Mifsud B, LeRoy K, Boeckman C, Huang E, Mathesius CA, Roper JM, Hurley BP. Evaluation of an in vitro experimental platform of human polarized intestinal epithelial monolayers for the hazard assessment of insecticidal proteins. Food Chem Toxicol. 2023 Nov;181:114106. doi: 10.1016/j.fct.2023.114106. Epub 2023 Oct 16. PubMed PMID: 37852351.

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Martinez J, Rodriguez Hovnanian KM, Martinez EE. Biomarkers and Functional Assays of Epithelial Barrier Disruption and Gastrointestinal Dysmotility in Critical Illness-A Narrative Review. Nutrients. 2023 Sep 19;15(18). doi: 10.3390/nu15184052. Review. PubMed PMID: 37764835; PubMed Central PMCID: PMC10535972.

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Zhang Y, Black KE, Phung TN, Thundivalappil SR, Lin T, Wang W, Xu J, Zhang C, Hariri LP, Lapey A, Li H, Lerou PH, Ai X, Que J, Park JA, Hurley BP, Mou H. Human Airway Basal Cells Undergo Reversible Squamous Differentiation and Reshape Innate Immunity. Am J Respir Cell Mol Biol. 2023 Jun;68(6):664-678. doi: 10.1165/rcmb.2022-0299OC. PubMed PMID: 36753317; PubMed Central PMCID: PMC10257070.

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Smith CJ, Rendina DN, Kingsbury MA, Malacon KE, Nguyen DM, Tran JJ, Devlin BA, Raju RM, Clark MJ, Burgett L, Zhang JH, Cetinbas M, Sadreyev RI, Chen K, Iyer MS, Bilbo SD. Microbial modulation via cross-fostering prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system. Mol Psychiatry. 2023 Jun;28(6):2549-2562. doi: 10.1038/s41380-023-02108-w. Epub 2023 May 17. PubMed PMID: 37198262; PubMed Central PMCID: PMC10719943.

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Su CW, Chen CY, Mao T, Chen N, Steudel N, Jiao L, Lan J, Fasano A, Walker WA, Shi HN. Maternal helminth infection protects offspring from high-fat-diet-induced obesity through altered microbiota and SCFAs. Cell Mol Immunol. 2023 Apr;20(4):389-403. doi: 10.1038/s41423-023-00979-1. Epub 2023 Feb 14. PubMed PMID: 36788341; PubMed Central PMCID: PMC10066288.

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Zhang Y, Lin T, Leung HM, Zhang C, Wilson-Mifsud B, Feldman MB, Puel A, Lanternier F, Couderc LJ, Danion F, Catherinot E, Salvator H, Tcherkian C, Givel C, Xu J, Tearney GJ, Vyas JM, Li H, Hurley BP, Mou H. STAT3 mutation-associated airway epithelial defects in Job syndrome. J Allergy Clin Immunol. 2023 Aug;152(2):538-550. doi: 10.1016/j.jaci.2022.12.821. Epub 2023 Jan 10. PubMed PMID: 36638921; PubMed Central PMCID: PMC10330947.

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Hopke A, Lin T, Scherer AK, Shay AE, Timmer KD, Wilson-Mifsud B, Mansour MK, Serhan CN, Irimia D, Hurley BP. Transcellular biosynthesis of leukotriene B(4) orchestrates neutrophil swarming to fungi. iScience. 2022 Oct 21;25(10):105226. doi: 10.1016/j.isci.2022.105226. eCollection 2022 Oct 21. PubMed PMID: 36267914; PubMed Central PMCID: PMC9576560.

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Martin VM, Virkud YV, Dahan E, Seay HL, Itzkovits D, Vlamakis H, Xavier R, Shreffler WG, Yuan Q, Yassour M. Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis. Microbiome. 2022 Sep 23;10(1):154. doi: 10.1186/s40168-022-01322-y. PubMed PMID: 36138438; PubMed Central PMCID: PMC9503280.

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Seay HL, Martin VM, Virkud YV, Marget M, Shreffler WG, Yuan Q. Prospective associations between acid suppressive therapy and food allergy in early childhood. Clin Exp Allergy. 2022 May;52(5):711-714. doi: 10.1111/cea.14123. PubMed PMID: 35285103; PubMed Central PMCID: PMC9248370.

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Samuels TL, Yan K, Patel N, Plehhova K, Coyle C, Hurley BP, Johnston N. Alginates for Protection Against Pepsin-Acid Induced Aerodigestive Epithelial Barrier Disruption. Laryngoscope. 2022 Dec;132(12):2327-2334. doi: 10.1002/lary.30087. Epub 2022 Mar 3. PubMed PMID: 35238407.

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Gorreja F, Walker WA. The potential role of adherence factors in probiotic function in the gastrointestinal tract of adults and pediatrics: a narrative review of experimental and human studies. Gut Microbes. 2022 Jan-Dec;14(1):2149214. doi: 10.1080/19490976.2022.2149214. Review. PubMed PMID: 36469568; PubMed Central PMCID: PMC9728474.

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Mehrotra I, Serena G, Cetinbas M, Kenyon V, Martin VM, Harshman SG, Zomorrodi AR, Sadreyev RI, Fasano A, Leonard MM. Characterization of the blood microbiota in children with Celiac disease. Curr Res Microb Sci. 2021 Dec;2:100069. doi: 10.1016/j.crmicr.2021.100069. eCollection 2021 Dec. PubMed PMID: 34841359; PubMed Central PMCID: PMC8610358.

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Yonker LM, Barrios J, Mou H, Hurley BP. Untapped Potential: Therapeutically Targeting Eicosanoids and Endocannabinoids in the Lung. Clin Pharmacol Ther. 2021 Jul;110(1):69-81. doi: 10.1002/cpt.2165. Epub 2021 Feb 13. Review. PubMed PMID: 33423293.

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Yonker LM, Marand A, Muldur S, Hopke A, Leung HM, De La Flor D, Park G, Pinsky H, Guthrie LB, Tearney GJ, Irimia D, Hurley BP. Neutrophil dysfunction in cystic fibrosis. J Cyst Fibros. 2021 Nov;20(6):1062-1071. doi: 10.1016/j.jcf.2021.01.012. Epub 2021 Feb 13. PubMed PMID: 33589340; PubMed Central PMCID: PMC8568301.

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Gao Y, Davis B, Zhu W, Zheng N, Meng D, Walker WA. Short-chain fatty acid butyrate, a breast milk metabolite, enhances immature intestinal barrier function genes in response to inflammation in vitro and in vivo. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G521-G530. doi: 10.1152/ajpgi.00279.2020. Epub 2020 Oct 21. PubMed PMID: 33085904; PubMed Central PMCID: PMC8238162.

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Gipson KS, Nickerson KP, Drenkard E, Llanos-Chea A, Dogiparthi SK, Lanter BB, Hibbler RM, Yonker LM, Hurley BP, Faherty CS. The Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens. Infect Immun. 2020 Sep 18;88(10). doi: 10.1128/IAI.00865-19. Print 2020 Sep 18. Review. PubMed PMID: 32661122; PubMed Central PMCID: PMC7504946.

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Martin VM, Virkud YV, Phadke NA, Su KW, Seay H, Atkins MR, Keet C, Shreffler WG, Yuan Q. Increased IgE-Mediated Food Allergy With Food Protein-Induced Allergic Proctocolitis. Pediatrics. 2020 Sep;146(3). doi: 10.1542/peds.2020-0202. PubMed PMID: 32855350; PubMed Central PMCID: PMC8323611.

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Bartley BL, Gardner KJ, Spina S, Hurley BP, Campeau D, Berra L, Yonker LM, Carroll RW. High-Dose Inhaled Nitric Oxide as Adjunct Therapy in Cystic Fibrosis Targeting Burkholderia multivorans. Case Rep Pediatr. 2020;2020:1536714. doi: 10.1155/2020/1536714. eCollection 2020. PubMed PMID: 32685229; PubMed Central PMCID: PMC7334765.

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Leung HM, Wang ML, Osman H, Abouei E, MacAulay C, Follen M, Gardecki JA, Tearney GJ. Imaging intracellular motion with dynamic micro-optical coherence tomography. Biomed Opt Express. 2020 May 1;11(5):2768-2778. doi: 10.1364/BOE.390782. eCollection 2020 May 1. PubMed PMID: 32499959; PubMed Central PMCID: PMC7249806.

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Feldman MB, Dutko RA, Wood MA, Ward RA, Leung HM, Snow RF, De La Flor DJ, Yonker LM, Reedy JL, Tearney GJ, Mou H, Hurley BP, Vyas JM. Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils. Infect Immun. 2020 Jan 22;88(2). doi: 10.1128/IAI.00813-19. Print 2020 Jan 22. PubMed PMID: 31767773; PubMed Central PMCID: PMC6977131.

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Ennamorati M, Vasudevan C, Clerkin K, Halvorsen S, Verma S, Ibrahim S, Prosper S, Porter C, Yeliseyev V, Kim M, Gardecki J, Sassi S, Tearney G, Cherayil BJ, Bry L, Seed B, Jain N. Intestinal microbes influence development of thymic lymphocytes in early life. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2570-2578. doi: 10.1073/pnas.1915047117. Epub 2020 Jan 21. PubMed PMID: 31964813; PubMed Central PMCID: PMC7007548.

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Martin VM, Virkud YV, Seay H, Hickey A, Ndahayo R, Rosow R, Southwick C, Elkort M, Gupta B, Kramer E, Pronchick T, Reuter S, Keet C, Su KW, Shreffler WG, Yuan Q. Prospective Assessment of Pediatrician-Diagnosed Food Protein-Induced Allergic Proctocolitis by Gross or Occult Blood. J Allergy Clin Immunol Pract. 2020 May;8(5):1692-1699.e1. doi: 10.1016/j.jaip.2019.12.029. Epub 2020 Jan 7. PubMed PMID: 31917366; PubMed Central PMCID: PMC8403015.

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Verma S, Prescott RA, Ingano L, Nickerson KP, Hill E, Faherty CS, Fasano A, Senger S, Cherayil BJ. The YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses. Gut Microbes. 2020 May 3;11(3):526-538. doi: 10.1080/19490976.2019.1697593. Epub 2019 Dec 12. PubMed PMID: 31829769; PubMed Central PMCID: PMC7527071.

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Chanin RB, Nickerson KP, Llanos-Chea A, Sistrunk JR, Rasko DA, Kumar DKV, de la Parra J, Auclair JR, Ding J, Li K, Dogiparthi SK, Kusber BJD, Faherty CS. Shigella flexneri Adherence Factor Expression in In Vivo-Like Conditions. mSphere. 2019 Nov 13;4(6). doi: 10.1128/mSphere.00751-19. PubMed PMID: 31722995; PubMed Central PMCID: PMC6854044.

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Serena G, Huynh D, Lima RS, Vise LM, Freire R, Ingano L, Leonard MM, Senger S, Fasano A. Intestinal Epithelium Modulates Macrophage Response to Gliadin in Celiac Disease. Front Nutr. 2019;6:167. doi: 10.3389/fnut.2019.00167. eCollection 2019. PubMed PMID: 31750310; PubMed Central PMCID: PMC6848268.

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Long SR, Lanter BB, Pazos MA, Mou H, Barrios J, Su CW, Wang ZQ, Walker WA, Hurley BP, Shi HN. Intestinal helminth infection enhances bacteria-induced recruitment of neutrophils to the airspace. Sci Rep. 2019 Oct 31;9(1):15703. doi: 10.1038/s41598-019-51991-3. PubMed PMID: 31673002; PubMed Central PMCID: PMC6823376.

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Hurley BP, Jugo RH, Snow RF, Samuels TL, Yonker LM, Mou H, Johnston N, Rosen R. Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium. Sci Rep. 2019 Sep 24;9(1):13778. doi: 10.1038/s41598-019-50360-4. PubMed PMID: 31551494; PubMed Central PMCID: PMC6760148.

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Leung HM, Birket SE, Hyun C, Ford TN, Cui D, Solomon GM, Shei RJ, Adewale AT, Lenzie AR, Fernandez-Petty CM, Zheng H, Palermo JH, Cho DY, Woodworth BA, Yonker LM, Hurley BP, Rowe SM, Tearney GJ. Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies. Sci Transl Med. 2019 Aug 7;11(504). doi: 10.1126/scitranslmed.aav3505. PubMed PMID: 31391319; PubMed Central PMCID: PMC6886258.

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Gorreja F, Rush ST, Kasper DL, Meng D, Walker WA. The developmentally regulated fetal enterocyte gene, ZP4, mediates anti-inflammation by the symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis. Am J Physiol Gastrointest Liver Physiol. 2019 Oct 1;317(4):G398-G407. doi: 10.1152/ajpgi.00046.2019. Epub 2019 Jul 17. PubMed PMID: 31314571; PubMed Central PMCID: PMC6842988.

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Lanter BB, Eaton AD, Roper JM, Zimmermann C, Delaney B, Hurley BP. Single versus repeated exposure to human polarized intestinal epithelial monolayers for in vitro protein hazard characterization. Food Chem Toxicol. 2019 Oct;132:110666. doi: 10.1016/j.fct.2019.110666. Epub 2019 Jul 6. PubMed PMID: 31288052.

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Falkard B, Charles RC, Matias WR, Mayo-Smith LM, Jerome JG, Offord ES, Xu P, Kováč P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. Bivalent oral cholera vaccination induces a memory B cell response to the V. cholerae O1-polysaccharide antigen in Haitian adults. PLoS Negl Trop Dis. 2019 Jan;13(1):e0007057. doi: 10.1371/journal.pntd.0007057. eCollection 2019 Jan. PubMed PMID: 30703094; PubMed Central PMCID: PMC6372202.

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Roushan M, Jorfi M, Mishra A, Wong KHK, Jorgensen J, Ell E, Markmann JF, Lee J, Irimia D. Trapped Chromatin Fibers Damage Flowing Red Blood Cells. Adv Biosyst. 2018 Oct;2(10). doi: 10.1002/adbi.201800040. Epub 2018 Aug 12. PubMed PMID: 31223642; PubMed Central PMCID: PMC6586417.

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Levardon H, Yonker LM, Hurley BP, Mou H. Expansion of Airway Basal Cells and Generation of Polarized Epithelium. Bio Protoc. 2018 Jun 5;8(11). doi: 10.21769/BioProtoc.2877. PubMed PMID: 30009215; PubMed Central PMCID: PMC6040659.

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Drenkard E, Hibbler RM, Gutu DA, Eaton AD, Silverio AL, Ausubel FM, Hurley BP, Yonker LM. Replication of the Ordered, Nonredundant Library of Pseudomonas aeruginosa strain PA14 Transposon Insertion Mutants. J Vis Exp. 2018 May 4;(135). doi: 10.3791/57298. PubMed PMID: 29781996; PubMed Central PMCID: PMC6101107.

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Zimmermann C, Eaton AD, Lanter BB, Roper J, Hurley BP, Delaney B. Extended exposure duration of cultured intestinal epithelial cell monolayers in characterizing hazardous and non-hazardous proteins. Food Chem Toxicol. 2018 May;115:451-459. doi: 10.1016/j.fct.2018.03.047. Epub 2018 Mar 31. PubMed PMID: 29614382.

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Su CW, Chen CY, Li Y, Long SR, Massey W, Kumar DV, Walker WA, Shi HN. Helminth infection protects against high fat diet-induced obesity via induction of alternatively activated macrophages. Sci Rep. 2018 Mar 15;8(1):4607. doi: 10.1038/s41598-018-22920-7. PubMed PMID: 29545532; PubMed Central PMCID: PMC5854586.

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Robinson A, Fiechtner L, Roche B, Ajami NJ, Petrosino JF, Camargo CA Jr, Taveras EM, Hasegawa K. Association of Maternal Gestational Weight Gain With the Infant Fecal Microbiota. J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):509-515. doi: 10.1097/MPG.0000000000001566. PubMed PMID: 28272161; PubMed Central PMCID: PMC5589469.

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Yonker LM, Pazos MA, Lanter BB, Mou H, Chu KK, Eaton AD, Bonventre JV, Tearney GJ, Rajagopal J, Hurley BP. Neutrophil-Derived Cytosolic PLA2α Contributes to Bacterial-Induced Neutrophil Transepithelial Migration. J Immunol. 2017 Oct 15;199(8):2873-2884. doi: 10.4049/jimmunol.1700539. Epub 2017 Sep 8. PubMed PMID: 28887431; PubMed Central PMCID: PMC5636676.

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Yonker LM, Mou H, Chu KK, Pazos MA, Leung H, Cui D, Ryu J, Hibbler RM, Eaton AD, Ford TN, Falck JR, Kinane TB, Tearney GJ, Rajagopal J, Hurley BP. Development of a Primary Human Co-Culture Model of Inflamed Airway Mucosa. Sci Rep. 2017 Aug 15;7(1):8182. doi: 10.1038/s41598-017-08567-w. PubMed PMID: 28811631; PubMed Central PMCID: PMC5557980.

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Pazos MA, Lanter BB, Yonker LM, Eaton AD, Pirzai W, Gronert K, Bonventre JV, Hurley BP. Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration. PLoS Pathog. 2017 Aug;13(8):e1006548. doi: 10.1371/journal.ppat.1006548. eCollection 2017 Aug. PubMed PMID: 28771621; PubMed Central PMCID: PMC5557605.

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Nickerson KP, Chanin RB, Sistrunk JR, Rasko DA, Fink PJ, Barry EM, Nataro JP, Faherty CS. Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts. Infect Immun. 2017 Jun;85(6). doi: 10.1128/IAI.01067-16. Print 2017 Jun. PubMed PMID: 28348056; PubMed Central PMCID: PMC5442615.

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Eaton AD, Zimmermann C, Delaney B, Hurley BP. Primary human polarized small intestinal epithelial barriers respond differently to a hazardous and an innocuous protein. Food Chem Toxicol. 2017 Aug;106(Pt A):70-77. doi: 10.1016/j.fct.2017.05.038. Epub 2017 May 19. PubMed PMID: 28533127.

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Chu KK, Kusek ME, Liu L, Som A, Yonker LM, Leung H, Cui D, Ryu J, Eaton AD, Tearney GJ, Hurley BP. Illuminating dynamic neutrophil trans-epithelial migration with micro-optical coherence tomography. Sci Rep. 2017 Apr 3;8:45789. doi: 10.1038/srep45789. PubMed PMID: 28368012; PubMed Central PMCID: PMC5377939.

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Hurley BP, Eaton AD, Zimmermann C, Delaney B. Polarized monolayer cultures of human intestinal epithelial cell lines exposed to intractable proteins - In vitro hazard identification studies. Food Chem Toxicol. 2016 Dec;98(Pt B):262-268. doi: 10.1016/j.fct.2016.11.006. Epub 2016 Nov 8. PubMed PMID: 27832974.

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Chen K, Shanmugam NK, Pazos MA, Hurley BP, Cherayil BJ. Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability. PLoS One. 2016;11(8):e0160937. doi: 10.1371/journal.pone.0160937. eCollection 2016. PubMed PMID: 27505062; PubMed Central PMCID: PMC4978417.

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Johnston N, Ondrey F, Rosen R, Hurley BP, Gould J, Allen J, DelGaudio J, Altman KW. Airway reflux. Ann N Y Acad Sci. 2016 Oct;1381(1):5-13. doi: 10.1111/nyas.13080. Epub 2016 Jun 16. Review. PubMed PMID: 27310222.

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Hurley BP, Pirzai W, Eaton AD, Harper M, Roper J, Zimmermann C, Ladics GS, Layton RJ, Delaney B. An experimental platform using human intestinal epithelial cell lines to differentiate between hazardous and non-hazardous proteins. Food Chem Toxicol. 2016 Jun;92:75-87. doi: 10.1016/j.fct.2016.04.003. Epub 2016 Apr 7. PubMed PMID: 27060235.