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Keele GR, Enger M, Barnette Q, Ruiz-Esparza R, Alvarado M, Mathur R, Stratford JK, Giamberardino SN, Brown LM, Webb BT, Carnes MU. Systematic Examination of Gene Expression and Proteomic Evidence Across Tissues Supports the Role of Mitochondrial Dysregulation in ME/CFS. Int J Mol Sci. 2026 Feb 19;27(4). doi: 10.3390/ijms27041997. PubMed PMID: 41752134; PubMed Central PMCID: PMC12940889.
Niarchou M, Tsai EL, Jennings MV, Faucon A, Lee H, Singh K, Tubbs JD, Roussos P, Ge T, Crist RC, Vickers-Smith R, Edenberg H, Moore A, Webb BT, Johnson EO, PsycheMERGE Substance Use Disorder Workgroup, Kember RL, Smoller JW, Davis LK, Coombes BJ, Voloudakis G, Burstein D, Mallard TT, Troiani V, Sanchez-Roige S. Optimizing Control Definitions in Opioid Use Disorder Genetic Research Using Electronic Health Records. Addict Biol. 2026 Jan;31(1):e70094. doi: 10.1111/adb.70094. PubMed PMID: 41549723; PubMed Central PMCID: PMC12813555.
Savage JE, Aliev F, Barr PB, Choi M, Drouard G, Cooke ME, Kuo SI, Stephenson M, Brislin SJ, Neale ZE, Spit for Science Working Group, COGA Investigators, Latvala A, Rose RJ, Kaprio J, Dick DM, Meyers J, Salvatore JE, Posthuma D. Trajectories of genetic risk across dimensions of alcohol use behaviors. Addiction. 2026 May;121(5):1153-1165. doi: 10.1111/add.70292. Epub 2025 Dec 23. PubMed PMID: 41437533; PubMed Central PMCID: PMC13088926.
Wolf HM, Romero R, Strauss JF 3rd, Tarca AL, Hassan SS, Webb BT, Latendresse SJ, York TP. Risk factors for spontaneous preterm birth are mediated through changes in cervical length. Commun Med (Lond). 2025 Dec 16;6(1):52. doi: 10.1038/s43856-025-01309-4. PubMed PMID: 41398068; PubMed Central PMCID: PMC12830857.
Grotzinger AD, Werme J, Peyrot WJ, Frei O, de Leeuw C, Bicks LK, Guo Q, Margolis MP, Coombes BJ, Batzler A, Pazdernik V, Biernacka JM, Andreassen OA, Anttila V, Børglum AD, Breen G, Cai N, Demontis D, Edenberg HJ, Faraone SV, Franke B, Gandal MJ, Gelernter J, Hatoum AS, Hettema JM, Johnson EC, Jonas KG, Knowles JA, Koenen KC, Maihofer AX, Mallard TT, Mattheisen M, Mitchell KS, Neale BM, Nievergelt CM, Nurnberger JI, O'Connell KS, Peterson RE, Robinson EB, Sanchez-Roige SS, Santangelo SL, Scharf JM, Stefansson H, Stefansson K, Stein MB, Strom NI, Thornton LM, Tucker-Drob EM, Verhulst B, Waldman ID, Walters GB, Wray NR, Yu D, Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Attention-Deficit/Hyperactivity Disorder (ADHD) Working Group of the Psychiatric Genomics Consortium, Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nicotine Dependence GenOmics (iNDiGO) Consortium, Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, Lee PH, Kendler KS, Smoller JW. Mapping the genetic landscape across 14 psychiatric disorders. Nature. 2026 Jan;649(8096):406-415. doi: 10.1038/s41586-025-09820-3. Epub 2025 Dec 10. PubMed PMID: 41372416; PubMed Central PMCID: PMC12779569.
Stratford JK, Carnes MU, Willis C, Minto MS, Elnimeiry L, Mathur R, Schu M, Quach BC, Carter J, Nolen T, Vandergrift N, Kosten TR, Johnson EO, Webb BT. Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databases. Transl Psychiatry. 2025 Nov 21;15(1):528. doi: 10.1038/s41398-025-03721-9. PubMed PMID: 41271629; PubMed Central PMCID: PMC12711988.
Webb BT, Gentry AE, Peterson RE, Keele GR, Carnes MU. Comprehensive multi-domain classification of Myalgic encephalomyelitis/chronic fatigue syndrome cases and controls in the UK Biobank increases heritability in contrast to single domain classification. American Society of Human Genetics; 2025 October; Boston, MA, USA. c2025.
Wolf HM, Webb BT, Strauss JF 3rd, Tarca AL, Romero R, Hassan SS, Latendresse SJ, Chaiworapongsa T, Berry S, Gomez-Lopez N, Chaemsaithong P, York TP. The genetic architecture of cervical length is shared with spontaneous preterm birth risk. Commun Med (Lond). 2025 Aug 14;5(1):352. doi: 10.1038/s43856-025-01078-0. PubMed PMID: 40813921; PubMed Central PMCID: PMC12354721.
Savage JE, Spit for Science Working Group, Dick DM, Posthuma D. Drinking motives and alcohol sensitivity mediate multidimensional genetic influences on alcohol use behaviors. Alcohol Clin Exp Res (Hoboken). 2025 May;49(5):1001-1012. doi: 10.1111/acer.70045. Epub 2025 Mar 31. PubMed PMID: 40165496; PubMed Central PMCID: PMC12098791.
Singh M, Chatzinakos C, Barr PB, Gentry AE, Bigdeli TB, Webb BT, Peterson RE. Trans-ancestry Genome-Wide Analyses in UK Biobank Yield Novel Risk Loci for Major Depression. medRxiv. 2025 Feb 24;. doi: 10.1101/2025.02.22.25322721. PubMed PMID: 40061314; PubMed Central PMCID: PMC11888526.
Hassan MF, Gentry AE, Prom-Wormley EC, Peterson RE, Webb BT. Machine Learning Approaches to Predict Alcohol Consumption from Biomarkers in the UK Biobank. medRxiv. 2024 Dec 24;. doi: 10.1101/2024.12.22.24319486. PubMed PMID: 39763569; PubMed Central PMCID: PMC11703295.
Webb BT, Moore A, Hassan MF, Peterson RE, Singh M, Riley BP, Bacanu SA, Nguyen TH, White JD, Hancock DB, Johnson EO, Gentry AE. Genetic architecture and comprehensive phenotypic assessment of alcohol use disorder and related outcomes in All of Us. American Society of Human Genetics; 2024 November; Denver, CO, USA. c2024.
White JD, Minto MS, Willis C, Quach BC, Han S, Tao R, Deep-Soboslay A, Zillich L, Witt SH, Spanagel R, Hansson AC, Clark SL, van den Oord EJCG, Hyde TM, Mayfield RD, Webb BT, Johnson EO, Kleinman JE, Bierut LJ, Hancock DB. Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex. Biol Psychiatry Glob Open Sci. 2024 Nov;4(6):100375. doi: 10.1016/j.bpsgos.2024.100375. eCollection 2024 Nov. PubMed PMID: 39399155; PubMed Central PMCID: PMC11470413.
Trastulla L, Dolgalev G, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Völzke H, Dörr M, Falkai P, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nat Commun. 2024 Jul 1;15(1):5534. doi: 10.1038/s41467-024-49338-2. PubMed PMID: 38951512; PubMed Central PMCID: PMC11217418.
Edwards AC, Singh M, Peterson RE, Webb BT, Gentry AE. Associations between polygenic liability to psychopathology and non-suicidal versus suicidal self-injury. Am J Med Genet B Neuropsychiatr Genet. 2024 Oct;195(7):e32982. doi: 10.1002/ajmg.b.32982. Epub 2024 Mar 29. PubMed PMID: 38551161; PubMed Central PMCID: PMC11438949.
Hagan KE, Johnson A, Venables K, Makara A, Spit for Science Working Group, Haynos AF. Naturalistic symptom trajectories of atypical anorexia nervosa, anorexia nervosa, and bulimia nervosa in a prospective cohort study of United States college students. Int J Eat Disord. 2024 Apr;57(4):924-936. doi: 10.1002/eat.24152. Epub 2024 Feb 2. PubMed PMID: 38303677; PubMed Central PMCID: PMC11018494.
White JD, Minto MS, Willis C, Quach BC, Han S, Tao R, Deep-Soboslay A, Zillich L, Clark SL, van den Oord EJCG, Hyde TM, Mayfield RD, Webb BT, Johnson EO, Kleinman JE, Bierut LJ, Hancock DB. Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex. medRxiv. 2024 Jan 17;. doi: 10.1101/2024.01.17.23300238. PubMed PMID: 38293028; PubMed Central PMCID: PMC10827272.
Sheerin CM, O'Hara-Payne RK, Lancaster EE, Suarez-Rivas H, Spit for Science Working Group, Chatzinakos C, Prom-Wormley EC, Peterson RE. Examining interactions between polygenic scores and interpersonal trauma exposure on alcohol consumption and use disorder in an ancestrally diverse college cohort. Front Genet. 2023;14:1274381. doi: 10.3389/fgene.2023.1274381. eCollection 2023. PubMed PMID: 38361984; PubMed Central PMCID: PMC10868390.
Ahangari M, Gentry AE, Hassan MF, Nguyen TH, Kendler KS, Bacanu SA, Peterson RE, Riley BP, Webb BT. Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information. bioRxiv. 2023 Sep 15;. doi: 10.1101/2023.09.11.557163. PubMed PMID: 37745400; PubMed Central PMCID: PMC10515858.
Thijssen AB, Spit for Science Working Group, Dick DM, Posthuma D, Savage JE. Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse. Mol Psychiatry. 2023 Oct;28(10):4225-4233. doi: 10.1038/s41380-023-02174-0. Epub 2023 Jul 25. PubMed PMID: 37488169; PubMed Central PMCID: PMC10827662.
Gentry AE, Kirkpatrick RM, Peterson RE, Webb BT. Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery. Front Genet. 2023;14:1162690. doi: 10.3389/fgene.2023.1162690. eCollection 2023. PubMed PMID: 37547462; PubMed Central PMCID: PMC10399453.
Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, Walters JTR, O'Donovan M, Sullivan P, Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, Brain Somatic Mosaicism Network, Sebat J, Lee EA, Walsh CA. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Cell Genom. 2023 Aug 9;3(8):100356. doi: 10.1016/j.xgen.2023.100356. eCollection 2023 Aug 9. PubMed PMID: 37601975; PubMed Central PMCID: PMC10435376.
Ahangari M, Bustamante D, Kirkpatrick R, Nguyen TH, Verrelli BC, Fanous A, Kendler KS, Webb BT, Bacanu SA, Riley BP. Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia. Br J Psychiatry. 2023 Jul;223(1):301-308. doi: 10.1192/bjp.2022.179. PubMed PMID: 36503694; PubMed Central PMCID: PMC10258219.
Wang X, Walker A, Revez JA, Ni G, Adams MJ, McIntosh AM, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Visscher PM, Wray NR. Polygenic risk prediction: why and when out-of-sample prediction R(2) can exceed SNP-based heritability. Am J Hum Genet. 2023 Jul 6;110(7):1207-1215. doi: 10.1016/j.ajhg.2023.06.006. Epub 2023 Jun 27. PubMed PMID: 37379836; PubMed Central PMCID: PMC10357496.
Gentry AE, Alexander JC, Ahangari M, Peterson RE, Miles MF, Bettinger JC, Davies AG, Groteweil M, Bacanu SA, Kendler KS, Riley BP, Webb BT, VCU Alcohol Research Center working group. Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach. PLoS One. 2023;18(4):e0283985. doi: 10.1371/journal.pone.0283985. eCollection 2023. PubMed PMID: 37098020; PubMed Central PMCID: PMC10128939.
Edwards AC, Gentry AE, Peterson RE, Webb BT, Mościcki EK. Multifaceted risk for non-suicidal self-injury only versus suicide attempt in a population-based cohort of adults. J Affect Disord. 2023 Jul 15;333:474-481. doi: 10.1016/j.jad.2023.04.040. Epub 2023 Apr 20. PubMed PMID: 37084979.
Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, Martin JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience. 2023 May 19;26(5):106701. doi: 10.1016/j.isci.2023.106701. eCollection 2023 May 19. PubMed PMID: 37207277; PubMed Central PMCID: PMC10189495.
Ahangari M, Kirkpatrick R, Nguyen TH, Gillespie N, Kendler KS, Bacanu SA, Webb BT, Verrelli BC, Riley BP. Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families. Schizophrenia (Heidelb). 2022 Nov 25;8(1):106. doi: 10.1038/s41537-022-00317-w. PubMed PMID: 36434002; PubMed Central PMCID: PMC9700852.
Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, Lai D, Bucholz K, Foroud T, Porjesz B, Runarsdottir V, Tyrfingsson T, Einarsson G, Gudbjartsson DF, Webb BT, Crist RC, Kranzler HR, Sherva R, Zhou H, Hulse G, Wildenauer D, Kelty E, Attia J, Holliday EG, McEvoy M, Scott RJ, Schwab SG, Maher BS, Gruza R, Kreek MJ, Nelson EC, Thorgeirsson T, Stefansson K, Berrettini WH, Gelernter J, Edenberg HJ, Bierut L, Hancock DB, Johnson EO. Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Sci Rep. 2022 Oct 7;12(1):16873. doi: 10.1038/s41598-022-21003-y. PubMed PMID: 36207451; PubMed Central PMCID: PMC9546890.
Bountress KE, Bustamante D, Subbie-Saenz de Viteri S, Chatzinakos C, Sheerin C, Daskalakis NP, Edenberg HJ, Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, Peterson RE, Webb BT, Meyers J, Amstadter A. Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes. Psychol Med. 2023 Sep;53(12):5767-5777. doi: 10.1017/S0033291722002999. Epub 2022 Sep 30. PubMed PMID: 36177877; PubMed Central PMCID: PMC10060434.
Johnson KF, Hood KB, Moreno O, Fuentes L, Williams CD, Vassileva J, Amstadter AB, Dick DM, Spit for Science Working Group. COVID-19-Induced Inequalities and Mental Health: Testing the Moderating Roles of Self-rated Health and Race/Ethnicity. J Racial Ethn Health Disparities. 2023 Oct;10(5):2093-2103. doi: 10.1007/s40615-022-01389-1. Epub 2022 Aug 26. PubMed PMID: 36018451; PubMed Central PMCID: PMC9415252.
Gillespie NA, Gentry AE, Kirkpatrick RM, Reynolds CA, Mathur R, Kendler KS, Maes HH, Webb BT, Peterson RE. Determining the stability of genome-wide factors in BMI between ages 40 to 69 years. PLoS Genet. 2022 Aug;18(8):e1010303. doi: 10.1371/journal.pgen.1010303. eCollection 2022 Aug. PubMed PMID: 35951648; PubMed Central PMCID: PMC9398001.
Ahangari M, Gentry AE, Irish Schizophrenia Genomics Consortium, Nguyen TH, Kirkpatrick R, Verrelli BC, Bacanu SA, Kendler KS, Webb BT, Riley BP. Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families. Transl Psychiatry. 2022 Jul 21;12(1):291. doi: 10.1038/s41398-022-02060-3. PubMed PMID: 35864105; PubMed Central PMCID: PMC9304393.
Ahangari M, Everest E, Nguyen TH, Verrelli BC, Webb BT, Bacanu SA, Tahir Turanli E, Riley BP. Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects. Brain Behav Immun. 2022 Aug;104:183-190. doi: 10.1016/j.bbi.2022.06.007. Epub 2022 Jun 14. PubMed PMID: 35714915; NIHMSID:NIHMS1851392.
Pain O, Hodgson K, Trubetskoy V, Ripke S, Marshe VS, Adams MJ, Byrne EM, Campos AI, Carrillo-Roa T, Cattaneo A, Als TD, Souery D, Dernovsek MZ, Fabbri C, Hayward C, Henigsberg N, Hauser J, Kennedy JL, Lenze EJ, Lewis G, Müller DJ, Martin NG, Mulsant BH, Mors O, Perroud N, Porteous DJ, Rentería ME, Reynolds CF 3rd, Rietschel M, Uher R, Wigmore EM, Maier W, Wray NR, Aitchison KJ, Arolt V, Baune BT, Biernacka JM, Bondolfi G, Domschke K, Kato M, Li QS, Liu YL, Serretti A, Tsai SJ, Turecki G, Weinshilboum R, GSRD Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, McIntosh AM, Lewis CM. Identifying the Common Genetic Basis of Antidepressant Response. Biol Psychiatry Glob Open Sci. 2022 Apr;2(2):115-126. doi: 10.1016/j.bpsgos.2021.07.008. PubMed PMID: 35712048; PubMed Central PMCID: PMC9117153.
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kučinskas V, Kučinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M Jr, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadić I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbaşoğlu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Müller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S, Indonesia Schizophrenia Consortium, PsychENCODE, Psychosis Endophenotypes International Consortium, SynGO Consortium, Adolfsson R, Arango C, Baune BT, Belangero SI, Børglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Jönsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Nöthen MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefánsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ, Roussos P, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O'Donovan MC, Schizophrenia Working Group of the Psychiatric Genomics Consortium. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. PubMed PMID: 35396580; PubMed Central PMCID: PMC9392466.
Svikis DS, Dillon PM, Meredith SE, Thacker LR, Polak K, Edwards AC, Pomm D, Dick D, Kendler K, Spit for Science Working Group. Coffee and energy drink use patterns in college freshmen: associations with adverse health behaviors and risk factors. BMC Public Health. 2022 Mar 26;22(1):594. doi: 10.1186/s12889-022-13012-3. PubMed PMID: 35346128; PubMed Central PMCID: PMC8962474.
Gentry AE, Alexander J, Peterson RE, Bacanu SA, Riley BP, Webb BT. Case-only rare variant analysis of severe alcohol dependence (AD) using a multivariate hierarchical gene clustering approach. Biorxiv 2022.03.16.484608 [Preprint]. 2022 March. 2022.03.16.484608Available from: https://www.biorxiv.org/content/10.1101/2022.03.16.484608v1. doi: https://doi.org/10.1101/2022.03.16.484608.
Wolf HM, Romero R, Strauss JF, Hassan SS, Latendresse SJ, Webb BT, Tarca AL, Gomez-Lopez N, Hsu CD, York TP. Study protocol to quantify the genetic architecture of sonographic cervical length and its relationship to spontaneous preterm birth. BMJ Open. 2022 Mar 17;12(3):e053631. doi: 10.1136/bmjopen-2021-053631. PubMed PMID: 35301205; PubMed Central PMCID: PMC8932269.
Bountress KE, Bustamante D, de Viteri SS, Chatzinakos C, Sheerin C, Peterson RE, Webb BT, Daskalakis NP, Edenberg H, Meyers J, Amstadter A. Differences in Genetic Correlations between Posttraumatic Stress Disorder and Alcohol Use Disorder-Related Phenotypes Compared to Alcohol Consumption-Related Phenotypes. medRxiv 2022.03.02.22271415 [Preprint]. 2022 March. 2022.03.02.22271415v1Available from: https://www. org/content/10.1101/2022.03.02.22271415v1. doi: https://doi.org/10.1101/2022.03.02.22271415.
Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR, Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC), Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia. JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001/jamapsychiatry.2021.3799. PubMed PMID: 35019943; PubMed Central PMCID: PMC8756361.
Giannakopoulou O, Lin K, Meng X, Su MH, Kuo PH, Peterson RE, Awasthi S, Moscati A, Coleman JRI, Bass N, Millwood IY, Chen Y, Chen Z, Chen HC, Lu ML, Huang MC, Chen CH, Stahl EA, Loos RJF, Mullins N, Ursano RJ, Kessler RC, Stein MB, Sen S, Scott LJ, Burmeister M, Fang Y, Tyrrell J, Jiang Y, Tian C, McIntosh AM, Ripke S, Dunn EC, Kendler KS, Walters RG, Lewis CM, Kuchenbaecker K, 23andMe Research Team . The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. JAMA Psychiatry. 2021 Nov 1;78(11):1258-1269. doi: 10.1001/jamapsychiatry.2021.2099. PubMed PMID: 34586374; PubMed Central PMCID: PMC8482304.
Webb BT, Gentry AE, Kirkpatrick RM, Maes HH, Reynolds CA, Mathur R, Neale MC, Kendler KS, Peterson RE. Stability of genetic influences on alcohol consumption and BMI across middle and late adulthood. European Neuropsychopharmacology. 2021 World Congress of Psychiatric Genetics; 2021 October; c2021.
Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fernández-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, Craddock N, Craig D, Degenhardt F, Djurovic S, Edenberg HJ, Fanous AH, Foo JC, Forstner AJ, Frye M, Fullerton JM, Gatt JM, Gejman PV, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamilton SP, Hamshere ML, Hartmann A, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Konte B, Krebs MO, Landén M, Lawrence J, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Lucae S, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Medland SE, Mehta D, Melle I, Milaneschi Y, Mitchell PB, Molina E, Morken G, Mortensen PB, Müller-Myhsok B, Nievergelt C, Nimgaonkar V, Nöthen MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Pimm J, Pistis G, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribasés M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Rujescu D, Sánchez-Mora C, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Shyn SI, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Spalletta G, Strauss JS, Świątkowska B, Trzaskowski M, Turecki G, Vilar-Ribó L, Vincent JB, Völzke H, Walters JTR, Shannon Weickert C, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Ashley-Koch AE, Beckham JC, Hauser ER, Hauser MA, Kimbrel NA, Lindquist JH, McMahon B, Oslin DW, Qin X, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup, VA Million Veteran Program, Agerbo E, Børglum AD, Breen G, Erlangsen A, Esko T, Gelernter J, Hougaard DM, Kessler RC, Kranzler HR, Li QS, Martin NG, McIntosh AM, Mors O, Nordentoft M, Olsen CM, Porteous D, Ursano RJ, Wasserman D, Werge T, Whiteman DC, Bulik CM, Coon H, Demontis D, Docherty AR, Kuo PH, Lewis CM, Mann JJ, Rentería ME, Smith DJ, Stahl EA, Stein MB, Streit F, Willour V, Ruderfer DM. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biol Psychiatry. 2022 Feb 1;91(3):313-327. doi: 10.1016/j.biopsych.2021.05.029. Epub 2021 Sep 9. PubMed PMID: 34861974; PubMed Central PMCID: PMC8851871.
Nguyen TH, He X, Brown RC, Webb BT, Kendler KS, Vladimirov VI, Riley BP, Bacanu SA. DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways. Brief Bioinform. 2021 Sep 2;22(5). doi: 10.1093/bib/bbab067. PubMed PMID: 33791774; PubMed Central PMCID: PMC8425460.
Gillespie NA, Gentry AE, Kirkpatrick RM, Maes HH, Reynolds CA, Mathur R, Kendler KS, Peterson RE, Webb BT. Determining the stability of genome-wide factors in BMI between ages 40 to 69 years. Biorxiv 2021.07.28.454172 [Preprint]. 2021 August. 2021.07.28.45417Available from: https://www.biorxiv.org/content/10.1101/2021.07.28.454172v2. doi: https://doi.org/10.1101/2021.07.28.454172.
Bountress KE, Wendt F, Bustamante D, Agrawal A, Webb B, Gillespie N, Edenberg H, Sheerin C, Johnson E, Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, Polimanti R, Amstadter A. Potential causal effect of posttraumatic stress disorder on alcohol use disorder and alcohol consumption in individuals of European descent: A Mendelian Randomization Study. Alcohol Clin Exp Res. 2021 Aug;45(8):1616-1623. doi: 10.1111/acer.14649. Epub 2021 Jun 24. PubMed PMID: 34120358; PubMed Central PMCID: PMC8429238.
Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Yang J, Visscher PM, Wray NR. A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts. Biol Psychiatry. 2021 Nov 1;90(9):611-620. doi: 10.1016/j.biopsych.2021.04.018. Epub 2021 May 4. PubMed PMID: 34304866; PubMed Central PMCID: PMC8500913.
Gentry AE. Missingness Adapted Group Informed Clustered (MAGIC)-LASSO: A novel paradigm for prediction in data with widespread non-random missingness. Biorxiv 2021.04.29.442057 [Preprint]. 2021 April. Available from: https://www.biorxiv.org/content/10.1101/2021.04.29.442057v1. doi: https://doi.org/10.1101/2021.04.29.442057.
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, Müller-Myhsok B, Świątkowska B, Schulze TG, Nöthen MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Landén M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Baune BT, Air T, Preisig M, Uher R, Levinson DF, Weissman MM, Potash JB, Shi J, Knowles JA, Perlis RH, Lucae S, Boomsma DI, Penninx BWJH, Hottenga JJ, de Geus EJC, Willemsen G, Milaneschi Y, Tiemeier H, Grabe HJ, Teumer A, Van der Auwera S, Völker U, Hamilton SP, Magnusson PKE, Viktorin A, Mehta D, Mullins N, Adams MJ, Breen G, McIntosh AM, Lewis CM, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, iPSYCH, Hougaard DM, Nordentoft M, Mors O, Mortensen PB, Werge T, Als TD, Børglum AD, Petryshen TL, Smoller JW, Goldstein JM. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23. PubMed PMID: 34099189; PubMed Central PMCID: PMC8458480.
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