My Bibliography

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London B. Immune Modulation of Cardiac Arrhythmias. Circ Res. 2017 Jun 23;121(1):11-12. doi: 10.1161/CIRCRESAHA.117.311214. PubMed PMID: 28642323; PubMed Central PMCID: PMC5798895.

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Yoon JY, Vikram A, London B, Irani K. Reversible lysine acetylation: Another layer of post-translational regulation of the cardiac sodium channel. Channels (Austin). 2017 Sep 3;11(5):360-361. doi: 10.1080/19336950.2017.1340015. Epub 2017 Jun 9. PubMed PMID: 28598266; PubMed Central PMCID: PMC5626356.

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Joy PS, Kumar G, Poole JE, London B, Olshansky B. Cardiac implantable electronic device infections: Who is at greatest risk?. Heart Rhythm. 2017 Jun;14(6):839-845. doi: 10.1016/j.hrthm.2017.03.019. Epub 2017 Mar 16. PubMed PMID: 28315744.

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Nagatomo Y, McNamara DM, Alexis JD, Cooper LT, Dec GW, Pauly DF, Sheppard R, Starling RC, Tang WH, IMAC-2 Investigators. Myocardial Recovery in Patients With Systolic Heart Failure and Autoantibodies Against β(1)-Adrenergic Receptors. J Am Coll Cardiol. 2017 Feb 28;69(8):968-977. doi: 10.1016/j.jacc.2016.11.067. PubMed PMID: 28231950; PubMed Central PMCID: PMC5330212.

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Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. PubMed PMID: 28191886; PubMed Central PMCID: PMC6218171.

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London B. Defining the Complexity of the Junctional Membrane Complex. Circ Res. 2017 Jan 6;120(1):11-12. doi: 10.1161/CIRCRESAHA.116.310214. PubMed PMID: 28057781; PubMed Central PMCID: PMC5798896.

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Ware JS, Li J, Mazaika E, Yasso CM, DeSouza T, Cappola TP, Tsai EJ, Hilfiker-Kleiner D, Kamiya CA, Mazzarotto F, Cook SA, Halder I, Prasad SK, Pisarcik J, Hanley-Yanez K, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Kealey A, Alexis J, Ramani G, Safirstein J, Boehmer J, Pauly DF, Wittstein IS, Thohan V, Zucker MJ, Liu P, Gorcsan J 3rd, McNamara DM, Seidman CE, Seidman JG, Arany Z, IMAC-2 and IPAC Investigators. Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. N Engl J Med. 2016 Jan 21;374(3):233-41. doi: 10.1056/NEJMoa1505517. Epub 2016 Jan 6. PubMed PMID: 26735901; PubMed Central PMCID: PMC4797319.

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Zhang Y, Blasco-Colmenares E, Harms AC, London B, Halder I, Singh M, Dudley SC, Gutmann R, Guallar E, Hankemeier T, Tomaselli GF, Cheng A. Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients. Europace. 2016 Sep;18(9):1383-90. doi: 10.1093/europace/euv342. Epub 2015 Oct 25. PubMed PMID: 26498162; PubMed Central PMCID: PMC5006959.

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Shusterman V, Troy WC, Abdelmessih M, Hoffman S, Nemec J, Strollo PJ, London B, Lampert R. Nighttime instabilities of neurophysiological, cardiovascular, and respiratory activity: integrative modeling and preliminary results. J Electrocardiol. 2015 Nov-Dec;48(6):1010-6. doi: 10.1016/j.jelectrocard.2015.08.017. Epub 2015 Aug 5. PubMed PMID: 26341647; PubMed Central PMCID: PMC4624504.

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Aleong RG, Mulvahill MJ, Halder I, Carlson NE, Singh M, Bloom HL, Dudley SC, Ellinor PT, Shalaby A, Weiss R, Gutmann R, Sauer WH, Narayanan K, Chugh SS, Saba S, London B. Left Ventricular Dilatation Increases the Risk of Ventricular Arrhythmias in Patients With Reduced Systolic Function. J Am Heart Assoc. 2015 Jul 31;4(8):e001566. doi: 10.1161/JAHA.114.001566. PubMed PMID: 26231842; PubMed Central PMCID: PMC4599449.

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Refaat MM, Hotait M, London B. Genetics of sudden cardiac death. Curr Cardiol Rep. 2015 Jul;17(7):606. doi: 10.1007/s11886-015-0606-8. Review. PubMed PMID: 26026997.

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Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L. Reconciling computer models and stem cell models of human cardiac repolarization: reply. Cardiovasc Res. 2015 Apr 1;106(1):6-7. doi: 10.1093/cvr/cvv039. Epub 2015 Feb 17. PubMed PMID: 25691542.

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Kim JJ, Yang L, Lin B, Zhu X, Sun B, Kaplan AD, Bett GC, Rasmusson RL, London B, Salama G. Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells. J Mol Cell Cardiol. 2015 Apr;81:81-93. doi: 10.1016/j.yjmcc.2015.01.013. Epub 2015 Jan 30. PubMed PMID: 25644533; PubMed Central PMCID: PMC4409767.

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AlJaroudi WA, Refaat MM, Habib RH, Al-Shaar L, Singh M, Gutmann R, Bloom HL, Dudley SC, Ellinor PT, Saba SF, Shalaby AA, Weiss R, McNamara DM, Halder I, London B, Genetic Risk Assessment of Defibrillator Events Investigators. Effect of angiotensin-converting enzyme inhibitors and receptor blockers on appropriate implantable cardiac defibrillator shock in patients with severe systolic heart failure (from the GRADE Multicenter Study). Am J Cardiol. 2015 Apr 1;115(7):924-31. doi: 10.1016/j.amjcard.2015.01.020. Epub 2015 Jan 15. PubMed PMID: 25682436; PubMed Central PMCID: PMC4363172.

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Narayanan K, Reinier K, Teodorescu C, Uy-Evanado A, Aleong R, Chugh H, Nichols GA, Gunson K, London B, Jui J, Chugh SS. Left ventricular diameter and risk stratification for sudden cardiac death. J Am Heart Assoc. 2014 Sep 16;3(5):e001193. doi: 10.1161/JAHA.114.001193. PubMed PMID: 25227407; PubMed Central PMCID: PMC4323796.

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Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L. Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells. Cardiovasc Res. 2014 Nov 1;104(2):258-69. doi: 10.1093/cvr/cvu205. Epub 2014 Sep 10. PubMed PMID: 25209314; PubMed Central PMCID: PMC4217687.

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London B. Searching for sudden death snps in calcium handling genes. J Am Heart Assoc. 2013 Oct 23;2(5):e000541. doi: 10.1161/JAHA.113.000541. PubMed PMID: 24152985; PubMed Central PMCID: PMC3835268.

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Goff JP, Shields DS, Wang H, Skoda EM, Sprachman MM, Wipf P, Garapati VK, Atkinson J, London B, Lazo JS, Kagan V, Epperly MW, Greenberger JS. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013 Nov;41(11):957-66. doi: 10.1016/j.exphem.2013.08.001. Epub 2013 Aug 7. PubMed PMID: 23933481; PubMed Central PMCID: PMC3834150.

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Blanco RR, Austin H, Vest RN 3rd, Valadri R, Li W, Lassegue B, Song Q, London B, Dudley SC, Bloom HL, Searles CD, Zafari AM. Angiotensin receptor type 1 single nucleotide polymorphism 1166A/C is associated with malignant arrhythmias and altered circulating miR-155 levels in patients with chronic heart failure. J Card Fail. 2012 Sep;18(9):717-23. doi: 10.1016/j.cardfail.2012.06.531. Epub 2012 Aug 9. PubMed PMID: 22939041; PubMed Central PMCID: PMC3640363.

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Scheuer J, London B. In memoriam tribute to James A. Shaver, MD. Circulation. 2012 Jul 31;126(5):615-6. doi: 10.1161/circulationaha.112.119222. PubMed PMID: 23025003.

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London B. Whither art thou, SCN10A, and what art thou doing?. Circ Res. 2012 Jul 20;111(3):268-70. doi: 10.1161/CIRCRESAHA.112.275032. PubMed PMID: 22821905.

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Zhu X, McTiernan CF, Rajagopalan N, Shah H, Fischer D, Toyoda Y, Letts D, Bortinger J, Gibson G, Xiang W, McCurry K, Mathier M, Glorioso JC, London B. Immunosuppression decreases inflammation and increases AAV6-hSERCA2a-mediated SERCA2a expression. Hum Gene Ther. 2012 Jul;23(7):722-32. doi: 10.1089/hum.2011.108. Epub 2012 Jul 11. PubMed PMID: 22482463; PubMed Central PMCID: PMC3404422.

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London B. FISHing for Answers in Postoperative Atrial Fibrillation. J Am Heart Assoc. 2012 Jun;1(3):e002931. doi: 10.1161/JAHA.112.002931. Epub 2012 Jun 22. PubMed PMID: 23130151; PubMed Central PMCID: PMC3487331.

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Shusterman V, Warman E, London B, Schwartzman D. Nocturnal peak in atrial tachyarrhythmia occurrence as a function of arrhythmia burden. J Cardiovasc Electrophysiol. 2012 Jun;23(6):604-11. doi: 10.1111/j.1540-8167.2011.02263.x. Epub 2012 Mar 19. PubMed PMID: 22429736; PubMed Central PMCID: PMC4569016.

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Refaat MM, Tanaka T, Kormos RL, McNamara D, Teuteberg J, Winowich S, London B, Simon MA. Survival benefit of implantable cardioverter-defibrillators in left ventricular assist device-supported heart failure patients. J Card Fail. 2012 Feb;18(2):140-5. doi: 10.1016/j.cardfail.2011.10.020. Epub 2011 Dec 22. PubMed PMID: 22300782; PubMed Central PMCID: PMC3272629.

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Petkova-Kirova PS, London B, Salama G, Rasmusson RL, Bondarenko VE. Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-α. Am J Physiol Heart Circ Physiol. 2012 Feb 15;302(4):H934-52. doi: 10.1152/ajpheart.00493.2011. Epub 2011 Nov 11. PubMed PMID: 22081697; PubMed Central PMCID: PMC3360583.

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Mezu U, Ch I, Halder I, London B, Saba S. Women and minorities are less likely to receive an implantable cardioverter defibrillator for primary prevention of sudden cardiac death. Europace. 2012 Mar;14(3):341-4. doi: 10.1093/europace/eur360. Epub 2011 Nov 8. PubMed PMID: 22071382.

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Saba S, Mehdi H, Shah H, Islam Z, Aoun E, Termanini S, Mahjoub R, Aleong R, McTiernan CF, London B. Cardiac levels of NOS1AP RNA from right ventricular tissue recovered during lead extraction. Heart Rhythm. 2012 Mar;9(3):399-404. doi: 10.1016/j.hrthm.2011.10.019. Epub 2011 Oct 19. PubMed PMID: 22019493.

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Refaat MM, Lubitz SA, Makino S, Islam Z, Frangiskakis JM, Mehdi H, Gutmann R, Zhang ML, Bloom HL, MacRae CA, Dudley SC, Shalaby AA, Weiss R, McNamara DM, London B, Ellinor PT. Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm. 2012 Mar;9(3):390-6. doi: 10.1016/j.hrthm.2011.10.016. Epub 2011 Oct 17. PubMed PMID: 22004663; PubMed Central PMCID: PMC3516872.

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Deng P, Pang ZP, Lei Z, Shikano S, Xiong Q, Harvey BK, London B, Wang Y, Li M, Xu ZC. Up-regulation of A-type potassium currents protects neurons against cerebral ischemia. J Cereb Blood Flow Metab. 2011 Sep;31(9):1823-35. doi: 10.1038/jcbfm.2011.88. Epub 2011 Jun 15. PubMed PMID: 21673715; PubMed Central PMCID: PMC3185888.

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Liu J, Kim KH, London B, Morales MJ, Backx PH. Dissection of the voltage-activated potassium outward currents in adult mouse ventricular myocytes: I(to,f), I(to,s), I(K,slow1), I(K,slow2), and I(ss). Basic Res Cardiol. 2011 Mar;106(2):189-204. doi: 10.1007/s00395-010-0134-z. Epub 2011 Jan 21. PubMed PMID: 21253754.

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McNamara DM, London B. GWAS applied to heart failure: bigger will be better...eventually. Circ Cardiovasc Genet. 2010 Jun;3(3):226-8. doi: 10.1161/CIRCGENETICS.110.957324. PubMed PMID: 20551418.

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Bloom HL, Shukrullah I, Veledar E, Gutmann R, London B, Dudley SC. Statins Decrease Oxidative Stress and ICD Therapies. Cardiol Res Pract. 2010;2010:253803. doi: 10.4061/2010/253803. Epub 2010 Mar 25. PubMed PMID: 20369058; PubMed Central PMCID: PMC2847377.

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Frangiskakis JM, London B. Targeting device therapy: genomics of sudden death. Heart Fail Clin. 2010 Jan;6(1):93-100. doi: 10.1016/j.hfc.2009.08.005. Review. PubMed PMID: 19945065; PubMed Central PMCID: PMC2833361.

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Saba S, Mehdi H, Mathier MA, Islam MZ, Salama G, London B. Effect of right ventricular versus biventricular pacing on electrical remodeling in the normal heart. Circ Arrhythm Electrophysiol. 2010 Feb;3(1):79-87. doi: 10.1161/CIRCEP.109.889741. Epub 2009 Dec 30. PubMed PMID: 20042767; PubMed Central PMCID: PMC2834320.

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Shusterman V, McTiernan CF, Goldberg A, Saba S, Salama G, London B. Adrenergic stimulation promotes T-wave alternans and arrhythmia inducibility in a TNF-alpha genetic mouse model of congestive heart failure. Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H440-50. doi: 10.1152/ajpheart.01024.2008. Epub 2009 Nov 25. PubMed PMID: 19940073; PubMed Central PMCID: PMC2822584.

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Liu M, Sanyal S, Gao G, Gurung IS, Zhu X, Gaconnet G, Kerchner LJ, Shang LL, Huang CL, Grace A, London B, Dudley SC Jr. Cardiac Na+ current regulation by pyridine nucleotides. Circ Res. 2009 Oct 9;105(8):737-45. doi: 10.1161/CIRCRESAHA.109.197277. Epub 2009 Sep 10. PubMed PMID: 19745168; PubMed Central PMCID: PMC2773656.

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Shusterman V, Lampert R, London B. The many faces of repolarization instability: which one is prognostic?. J Electrocardiol. 2009 Nov-Dec;42(6):511-6. doi: 10.1016/j.jelectrocard.2009.06.008. Epub 2009 Aug 29. Review. PubMed PMID: 19717165; PubMed Central PMCID: PMC2767468.

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Frangiskakis JM, Hravnak M, Crago EA, Tanabe M, Kip KE, Gorcsan J 3rd, Horowitz MB, Kassam AB, London B. Ventricular arrhythmia risk after subarachnoid hemorrhage. Neurocrit Care. 2009;10(3):287-94. doi: 10.1007/s12028-009-9188-x. Epub 2009 Jan 28. PubMed PMID: 19184553; PubMed Central PMCID: PMC3673292.

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Salama G, Baker L, Wolk R, Barhanin J, London B. Arrhythmia phenotype in mouse models of human long QT. J Interv Card Electrophysiol. 2009 Mar;24(2):77-87. doi: 10.1007/s10840-008-9339-6. Epub 2009 Jan 16. PubMed PMID: 19148726.

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Shusterman V, McTiernan CF, Mehdi H, Troy WC, London B. Circadian pattern to arrhythmias in a genetic mouse model of heart failure. Computers in cardiology. 2009; 36:341-344.

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London B. Understanding cardiac calcium channelopathies. Circulation. 2008 Nov 25;118(22):2221-2. doi: 10.1161/CIRCULATIONAHA.108.819847. PubMed PMID: 19029476.

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Teng GQ, Zhao X, Lees-Miller JP, Quinn FR, Li P, Rancourt DE, London B, Cross JC, Duff HJ. Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality. Circ Res. 2008 Dec 5;103(12):1483-91. doi: 10.1161/CIRCRESAHA.108.177055. Epub 2008 Oct 23. PubMed PMID: 18948620; PubMed Central PMCID: PMC2774899.

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Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 2008 Sep 9;118(11):1202-11. doi: 10.1161/CIRCULATIONAHA.108.772715. PubMed PMID: 18779456; PubMed Central PMCID: PMC2908516.

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Hajjar RJ, Zsebo K, Deckelbaum L, Thompson C, Rudy J, Yaroshinsky A, Ly H, Kawase Y, Wagner K, Borow K, Jaski B, London B, Greenberg B, Pauly DF, Patten R, Starling R, Mancini D, Jessup M. Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. J Card Fail. 2008 Jun;14(5):355-67. doi: 10.1016/j.cardfail.2008.02.005. Epub 2008 May 27. PubMed PMID: 18514926.

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London B. An irregularly irregular inheritance. J Am Coll Cardiol. 2008 Mar 18;51(11):1090-1. doi: 10.1016/j.jacc.2007.12.011. PubMed PMID: 18342227.

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Van Norstrand DW, Valdivia CR, Tester DJ, Ueda K, London B, Makielski JC, Ackerman MJ. Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. Circulation. 2007 Nov 13;116(20):2253-9. doi: 10.1161/CIRCULATIONAHA.107.704627. Epub 2007 Oct 29. PubMed PMID: 17967976; PubMed Central PMCID: PMC3332545.

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London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC Jr. Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. Circulation. 2007 Nov 13;116(20):2260-8. doi: 10.1161/CIRCULATIONAHA.107.703330. Epub 2007 Oct 29. PubMed PMID: 17967977; PubMed Central PMCID: PMC3150966.

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Saba S, Mathier MA, Mehdi H, Liu T, Choi BR, London B, Salama G. Dual-dye optical mapping after myocardial infarction: does the site of ventricular stimulation alter the properties of electrical propagation?. J Cardiovasc Electrophysiol. 2008 Feb;19(2):197-202. doi: 10.1111/j.1540-8167.2007.00998.x. Epub 2007 Oct 24. PubMed PMID: 17971142.

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McTiernan CF, Mathier MA, Zhu X, Xiao X, Klein E, Swan CH, Mehdi H, Gibson G, Trichel AM, Glorioso JC, Feldman AM, McCurry KR, London B. Myocarditis following adeno-associated viral gene expression of human soluble TNF receptor (TNFRII-Fc) in baboon hearts. Gene Ther. 2007 Dec;14(23):1613-22. doi: 10.1038/sj.gt.3303020. Epub 2007 Sep 13. PubMed PMID: 17851548.