Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Nayak L, Sweet DR, Thomas A, Lapping SD, Kalikasingh K, Madera A, Vinayachandran V, Padmanabhan R, Vasudevan NT, Myers JT, Huang AY, Schmaier A, Mackman N, Liao X, Maiseyeu A, Jain MK. A targetable pathway in neutrophils mitigates both arterial and venous thrombosis. Sci Transl Med. 2022 Aug 31;14(660):eabj7465. doi: 10.1126/scitranslmed.abj7465. Epub 2022 Aug 31. PubMed PMID: 36044595.
Motairek I, Janus SE, Hajjari J, Nasir K, Khan SU, Rajagopalan S, Al-Kindi S. Social Vulnerability and Excess Mortality in the COVID-19 Era. Am J Cardiol. 2022 Jun 1;172:172-174. doi: 10.1016/j.amjcard.2022.03.011. Epub 2022 Apr 4. PubMed PMID: 35393083; PubMed Central PMCID: PMC8979474.
Maiseyeu A, Di L, Ravodina A, Barajas-Espinosa A, Sakamoto A, Chaplin A, Zhong J, Gao H, Mignery M, Narula N, Finn AV, Rajagopalan S. Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis. Theranostics. 2022;12(6):2741-2757. doi: 10.7150/thno.66456. eCollection 2022. PubMed PMID: 35401813; PubMed Central PMCID: PMC8965488.
Di L, Maiseyeu A. Low-density lipoprotein nanomedicines: mechanisms of targeting, biology, and theranostic potential. Drug Deliv. 2021 Dec;28(1):408-421. doi: 10.1080/10717544.2021.1886199. Review. PubMed PMID: 33594923; PubMed Central PMCID: PMC7894439.
Ravodina AM, Badgeley MA, Rajagopalan S, Fedyukina DV, Maiseyeu A. Facile Cholesterol Loading with a New Probe ezFlux Allows for Streamlined Cholesterol Efflux Assays. ACS Omega. 2020 Sep 15;5(36):23289-23298. doi: 10.1021/acsomega.0c03112. eCollection 2020 Sep 15. PubMed PMID: 32954180; PubMed Central PMCID: PMC7495719.
Gangwar RS, Vinayachandran V, Rengasamy P, Chan R, Park B, Diamond-Zaluski R, Cara EA, Cha A, Das L, Asase C, Maiseyeu A, Deiuliis J, Zhong J, Mitzner W, Biswal S, Rajagopalan S. Differential contribution of bone marrow-derived infiltrating monocytes and resident macrophages to persistent lung inflammation in chronic air pollution exposure. Sci Rep. 2020 Sep 1;10(1):14348. doi: 10.1038/s41598-020-71144-1. PubMed PMID: 32873817; PubMed Central PMCID: PMC7462977.
Chaplin A, Gao H, Asase C, Rengasamy P, Park B, Skander D, Bebek G, Rajagopalan S, Maiseyeu A. Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse model. Sci Rep. 2020 Aug 14;10(1):13786. doi: 10.1038/s41598-020-69745-x. PubMed PMID: 32796856; PubMed Central PMCID: PMC7429827.
Jayaraj P, Narasimhulu CA, Maiseyeu A, Durairaj R, Rao S, Rajagopalan S, Parthasarathy S, Desikan R. Methoxyphenol derivatives as reversible inhibitors of myeloperoxidase as potential antiatherosclerotic agents. Future Med Chem. 2020 Jan;12(2):95-110. doi: 10.4155/fmc-2019-0080. Epub 2019 Nov 26. PubMed PMID: 31769316; PubMed Central PMCID: PMC7333589.
Reyes-Caballero H, Rao X, Sun Q, Warmoes MO, Lin P, Sussan TE, Park B, Fan TW, Maiseyeu A, Rajagopalan S, Girnun GD, Biswal S. Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice. Sci Rep. 2019 Nov 22;9(1):17423. doi: 10.1038/s41598-019-53716-y. PubMed PMID: 31757983; PubMed Central PMCID: PMC6874681.
Mog B, Asase C, Chaplin A, Gao H, Rajagopalan S, Maiseyeu A. Nano-Antagonist Alleviates Inflammation and Allows for MRI of Atherosclerosis. Nanotheranostics. 2019;3(4):342-355. doi: 10.7150/ntno.37391. eCollection 2019. PubMed PMID: 31723548; PubMed Central PMCID: PMC6838142.
Yasmeen R, Shen Q, Lee A, Leung JH, Kowdley D, DiSilvestro DJ, Xu L, Yang K, Maiseyeu A, Bal NC, Periasamy M, Fadda P, Ziouzenkova O. Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice. J Endocrinol. 2018 Dec 1;239(3):377-388. doi: 10.1530/JOE-18-0289. PubMed PMID: 30400011; PubMed Central PMCID: PMC6226053.
Yao Z, Mates JM, Cheplowitz AM, Hammer LP, Maiseyeu A, Phillips GS, Wewers MD, Rajaram MV, Robinson JM, Anderson CL, Ganesan LP. Blood-Borne Lipopolysaccharide Is Rapidly Eliminated by Liver Sinusoidal Endothelial Cells via High-Density Lipoprotein. J Immunol. 2016 Sep 15;197(6):2390-9. doi: 10.4049/jimmunol.1600702. Epub 2016 Aug 17. PubMed PMID: 27534554; PubMed Central PMCID: PMC5010928.
Maiseyeu A. Non-antigenic regulators of targeting for imaging and therapy. Adv Drug Deliv Rev. 2016 Apr 1;99(Pt A):1. doi: 10.1016/j.addr.2016.02.009. PubMed PMID: 26987405.
Bagalkot V, Deiuliis JA, Rajagopalan S, Maiseyeu A. "Eat me" imaging and therapy. Adv Drug Deliv Rev. 2016 Apr 1;99(Pt A):2-11. doi: 10.1016/j.addr.2016.01.009. Epub 2016 Jan 27. Review. PubMed PMID: 26826436; PubMed Central PMCID: PMC4865253.
Ganesan LP, Mates JM, Cheplowitz AM, Avila CL, Zimmerer JM, Yao Z, Maiseyeu A, Rajaram MV, Robinson JM, Anderson CL. Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells. Sci Rep. 2016 Feb 11;6:20646. doi: 10.1038/srep20646. PubMed PMID: 26865459; PubMed Central PMCID: PMC4749959.
Bagalkot V, Badgeley MA, Kampfrath T, Deiuliis JA, Rajagopalan S, Maiseyeu A. Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals. J Control Release. 2015 Nov 10;217:243-55. doi: 10.1016/j.jconrel.2015.09.027. Epub 2015 Sep 18. PubMed PMID: 26386437; PubMed Central PMCID: PMC4874242.
Zhong J, Maiseyeu A, Davis SN, Rajagopalan S. DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. Circ Res. 2015 Apr 10;116(8):1491-504. doi: 10.1161/CIRCRESAHA.116.305665. Review. PubMed PMID: 25858071; PubMed Central PMCID: PMC4394189.
Zhong J, Maiseyeu A, Rajagopalan S. Lipoprotein effects of incretin analogs and dipeptidyl peptidase 4 inhibitors. Clin Lipidol. 2015;10(1):103-112. doi: 10.2217/clp.14.59. PubMed PMID: 26005496; PubMed Central PMCID: PMC4437760.
Liu C, Fonken LK, Wang A, Maiseyeu A, Bai Y, Wang TY, Maurya S, Ko YA, Periasamy M, Dvonch T, Morishita M, Brook RD, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson RJ, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Part Fibre Toxicol. 2014 Oct 30;11:53. doi: 10.1186/s12989-014-0053-5. PubMed PMID: 25358444; PubMed Central PMCID: PMC4226918.
Rao X, Zhong J, Maiseyeu A, Gopalakrishnan B, Villamena FA, Chen LC, Harkema JR, Sun Q, Rajagopalan S. CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure. Circ Res. 2014 Oct 10;115(9):770-780. doi: 10.1161/CIRCRESAHA.115.304666. Epub 2014 Sep 3. PubMed PMID: 25186795; PubMed Central PMCID: PMC4275116.
Maiseyeu A, Bagalkot V. In vitro uptake of apoptotic body mimicking phosphatidylserine-quantum dot micelles by monocytic cell line. Nanoscale Res Lett. 2014;9(1):176. doi: 10.1186/1556-276X-9-176. eCollection 2014. PubMed PMID: 24725273; PubMed Central PMCID: PMC4022335.
Deiuliis J, Mihai G, Zhang J, Taslim C, Varghese JJ, Maiseyeu A, Huang K, Rajagopalan S. Renin-sensitive microRNAs correlate with atherosclerosis plaque progression. J Hum Hypertens. 2014 Apr;28(4):251-8. doi: 10.1038/jhh.2013.97. Epub 2013 Oct 24. PubMed PMID: 24152824.
Liu C, Xu X, Bai Y, Wang TY, Rao X, Wang A, Sun L, Ying Z, Gushchina L, Maiseyeu A, Morishita M, Sun Q, Harkema JR, Rajagopalan S. Air pollution-mediated susceptibility to inflammation and insulin resistance: influence of CCR2 pathways in mice. Environ Health Perspect. 2014 Jan;122(1):17-26. doi: 10.1289/ehp.1306841. Epub 2013 Oct 22. PubMed PMID: 24149114; PubMed Central PMCID: PMC3888572.
Giri S, Xue H, Maiseyeu A, Kroeker R, Rajagopalan S, White RD, Zuehlsdorff S, Raman SV, Simonetti OP. Steady-state first-pass perfusion (SSFPP): a new approach to 3D first-pass myocardial perfusion imaging. Magn Reson Med. 2014 Jan;71(1):133-44. doi: 10.1002/mrm.24638. Epub 2013 Feb 25. PubMed PMID: 23440705; PubMed Central PMCID: PMC3664646.
Maiseyeu A, Yang HY, Ramanathan G, Yin F, Bard RL, Morishita M, Dvonch JT, Wang L, Spino C, Mukherjee B, Badgeley MA, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo JA, Brook RD. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhal Toxicol. 2014 Jan;26(1):23-9. doi: 10.3109/08958378.2013.850761. PubMed PMID: 24417404; PubMed Central PMCID: PMC4445365.
Cholesterol efflux assay probe formulations, methods of making and using. USA WO2013155374 A3. 2013 December.
Blazek A, Rutsky J, Osei K, Maiseyeu A, Rajagopalan S. Exercise-mediated changes in high-density lipoprotein: impact on form and function. Am Heart J. 2013 Sep;166(3):392-400. doi: 10.1016/j.ahj.2013.05.021. Epub 2013 Jul 3. Review. PubMed PMID: 24016485.
Sun L, Liu C, Xu X, Ying Z, Maiseyeu A, Wang A, Allen K, Lewandowski RP, Bramble LA, Morishita M, Wagner JG, Dvonch J, Sun Z, Yan X, Brook RD, Rajagopalan S, Harkema JR, Sun Q, Fan Z. Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet. Part Fibre Toxicol. 2013 Aug 22;10:43. doi: 10.1186/1743-8977-10-43. PubMed PMID: 23968387; PubMed Central PMCID: PMC3765456.
Mihai G, Varghese J, Kampfrath T, Gushchina L, Hafer L, Deiuliis J, Maiseyeu A, Simonetti OP, Lu B, Rajagopalan S. Aliskiren effect on plaque progression in established atherosclerosis using high resolution 3D MRI (ALPINE): a double-blind placebo-controlled trial. J Am Heart Assoc. 2013 May 17;2(3):e004879. doi: 10.1161/JAHA.112.004879. PubMed PMID: 23686372; PubMed Central PMCID: PMC3698800.
Sharkey-Toppen TP, Mihai G, Maiseyeu A, Tran T, Clymer BD, Simonetti OP, Raman SV. Improved in vivo human carotid artery wall T₂ estimation. Magn Reson Imaging. 2013 Jan;31(1):44-52. doi: 10.1016/j.mri.2012.06.006. Epub 2012 Aug 22. PubMed PMID: 22921942; PubMed Central PMCID: PMC3568391.
Liu C, Desikan R, Ying Z, Gushchina L, Kampfrath T, Deiuliis J, Wang A, Xu X, Zhong J, Rao X, Sun Q, Maiseyeu A, Parthasarathy S, Rajagopalan S. Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model. PLoS One. 2012;7(12):e50767. doi: 10.1371/journal.pone.0050767. Epub 2012 Dec 10. PubMed PMID: 23251382; PubMed Central PMCID: PMC3519467.
Xu X, Rao X, Wang TY, Jiang SY, Ying Z, Liu C, Wang A, Zhong M, Deiuliis JA, Maiseyeu A, Rajagopalan S, Lippmann M, Chen LC, Sun Q. Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model. Part Fibre Toxicol. 2012 Nov 5;9:40. doi: 10.1186/1743-8977-9-40. PubMed PMID: 23126276; PubMed Central PMCID: PMC3545913.
Bandyopadhyay S, Xia X, Maiseiyeu A, Mihai G, Rajagopalan S, Bong D. Z-Group ketone chain transfer agents for RAFT polymer nanoparticle modification via hydrazone conjugation. Macromolecules. 2012 Sep 11;45(17):6766-6773. doi: 10.1021/ma301536f. Epub 2012 Aug 30. PubMed PMID: 23148126; PubMed Central PMCID: PMC3494100.
Yang F, Zhang X, Maiseyeu A, Mihai G, Yasmeen R, DiSilvestro D, Maurya SK, Periasamy M, Bergdall KV, Duester G, Sen CK, Roy S, Lee LJ, Rajagopalan S, Ziouzenkova O. The prolonged survival of fibroblasts with forced lipid catabolism in visceral fat following encapsulation in alginate-poly-L-lysine. Biomaterials. 2012 Aug;33(22):5638-49. doi: 10.1016/j.biomaterials.2012.04.035. Epub 2012 May 9. PubMed PMID: 22575837; PubMed Central PMCID: PMC3815596.
Ying Z, Desikan R, Xu X, Maiseyeu A, Liu C, Sun Q, Ziouzenkova O, Parthasarathy S, Rajagopalan S. Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression. J Lipid Res. 2012 May;53(5):879-887. doi: 10.1194/jlr.M022806. Epub 2012 Feb 21. PubMed PMID: 22355094; PubMed Central PMCID: PMC3329387.
Maiseyeu A, Badgeley MA, Kampfrath T, Mihai G, Deiuliis JA, Liu C, Sun Q, Parthasarathy S, Simon DI, Croce K, Rajagopalan S. In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):962-70. doi: 10.1161/ATVBAHA.111.244509. Epub 2012 Feb 2. PubMed PMID: 22308043; PubMed Central PMCID: PMC3348503.
Deiuliis JA, Kampfrath T, Zhong J, Oghumu S, Maiseyeu A, Chen LC, Sun Q, Satoskar AR, Rajagopalan S. Pulmonary T cell activation in response to chronic particulate air pollution. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 15;302(4):L399-409. doi: 10.1152/ajplung.00261.2011. Epub 2011 Dec 9. PubMed PMID: 22160305; PubMed Central PMCID: PMC3289266.
Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S. Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis. Circulation. 2011 Nov 22;124(21):2338-49. doi: 10.1161/CIRCULATIONAHA.111.041418. Epub 2011 Oct 17. PubMed PMID: 22007077; PubMed Central PMCID: PMC4224594.
Deiuliis JA, Kampfrath T, Ying Z, Maiseyeu A, Rajagopalan S. Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice. Lipids. 2011 Nov;46(11):1021-32. doi: 10.1007/s11745-011-3603-8. Epub 2011 Aug 23. PubMed PMID: 21861137; PubMed Central PMCID: PMC4849868.
Shah Z, Pineda C, Kampfrath T, Maiseyeu A, Ying Z, Racoma I, Deiuliis J, Xu X, Sun Q, Moffatt-Bruce S, Villamena F, Rajagopalan S. Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways. Vascul Pharmacol. 2011 Jul-Sep;55(1-3):2-9. doi: 10.1016/j.vph.2011.03.001. Epub 2011 Mar 10. PubMed PMID: 21397040; PubMed Central PMCID: PMC4845951.
Reichert B, Yasmeen R, Jeyakumar SM, Yang F, Thomou T, Alder H, Duester G, Maiseyeu A, Mihai G, Harrison EH, Rajagopalan S, Kirkland JL, Ziouzenkova O. Concerted action of aldehyde dehydrogenases influences depot-specific fat formation. Mol Endocrinol. 2011 May;25(5):799-809. doi: 10.1210/me.2010-0465. Epub 2011 Mar 24. PubMed PMID: 21436255; PubMed Central PMCID: PMC3082326.
Kampfrath T, Maiseyeu A, Ying Z, Shah Z, Deiuliis JA, Xu X, Kherada N, Brook RD, Reddy KM, Padture NP, Parthasarathy S, Chen LC, Moffatt-Bruce S, Sun Q, Morawietz H, Rajagopalan S. Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways. Circ Res. 2011 Mar 18;108(6):716-26. doi: 10.1161/CIRCRESAHA.110.237560. Epub 2011 Jan 27. PubMed PMID: 21273555; PubMed Central PMCID: PMC3085907.
Maiseyeu A, Mihai G, Roy S, Kherada N, Simonetti OP, Sen CK, Sun Q, Parthasarathy S, Rajagopalan S. Detection of macrophages via paramagnetic vesicles incorporating oxidatively tailored cholesterol ester: an approach for atherosclerosis imaging. Nanomedicine (Lond). 2010 Nov;5(9):1341-56. doi: 10.2217/nnm.10.87. PubMed PMID: 21128718; PubMed Central PMCID: PMC3098505.
Maiseyeu A, Mihai G, Kampfrath T, Simonetti OP, Sen CK, Roy S, Rajagopalan S, Parthasarathy S. Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis. J Lipid Res. 2009 Nov;50(11):2157-63. doi: 10.1194/jlr.M800405-JLR200. Epub 2008 Nov 17. PubMed PMID: 19017616; PubMed Central PMCID: PMC2759821.
Moiseev A, Balenkova E, Nenadenko V. Thiophene 1, 1-dioxides as unique building blocks in modern organic synthesis and materials chemistry. Russian Chemical Reviews. 2006; 75:1015. doi:
Moiseev A, Balenkova E, Nenajdenko V. Reactions of electron-withdrawing thiophene 1, 1-dioxides with furans. A novel reaction pathway. Russian chemical bulletin. 2006; 55(4):712. doi: 10.1007/s11172-006-0318-8.
Moiseev A, Tyurin D, Balenkova E, Nenajdenko V. Reactions of acceptor substituted thiophene-1, 1-dioxides with cyclopentadiene: control of selectivity by substitution. Tetrahedron. 2006; 62(17):4135. doi:
Moiseev A, Balenkova E, Nenajdenko V. [6+ 4] Cycloaddition reactions of acceptor thiophene dioxides: The synthesis of substituted azulenes. Russian chemical bulletin. 2006; 55(1):141. doi: 10.1007/s11172-006-0227-x.
Moiseev A, Balenkova E, Nenajdenko V. EWG-containing thiophene-and 2-thiolene-1, 1-dioxides as promising electrophiles for organic synthesis. Mendeleev Communications. 2006; 4(16):215. doi:
Nenajdenko VG, Moiseev AM, Balenkova ES. Chemo-, regio- and stereoselective Diels–Alder reactions of EWG bearing thiophene-1,1-dioxides. Tetrahedron. 2005; 61:10880. doi: 10.1016/j.tet.2005.09.006.
What would you like to do?