Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Szymczuk V, Florenzano P, de Castro LF, Collins MT, Boyce AM. Fibrous Dysplasia / McCune-Albright Syndrome. 1993;. Review. PubMed PMID: 25719192.
Boyce AM. Fibrous Dysplasia. 2000;. Review. PubMed PMID: 26561700.
Boyce AM, Gafni RI. Approach to the child with fractures. J Clin Endocrinol Metab. 2011 Jul;96(7):1943-52. doi: 10.1210/jc.2010-2546. PubMed PMID: 21734001; PubMed Central PMCID: PMC3135196.
Boyce AM, Gafni RI. Child with fractures.. In: Wartofsy L, editor. A Clinical Approach to Endocrine and Metabolic Diseases 2 ed. Chevy Chase, MD: The Endocrine Society; 2012. 308-322p.
Boyce AM, Chong WH, Yao J, Gafni RI, Kelly MH, Chamberlain CE, Bassim C, Cherman N, Ellsworth M, Kasa-Vubu JZ, Farley FA, Molinolo AA, Bhattacharyya N, Collins MT. Denosumab treatment for fibrous dysplasia. J Bone Miner Res. 2012 Jul;27(7):1462-70. doi: 10.1002/jbmr.1603. PubMed PMID: 22431375; PubMed Central PMCID: PMC3377825.
Neary NM, Lopez-Chavez A, Abel BS, Boyce AM, Schaub N, Kwong K, Stratakis CA, Moran CA, Giaccone G, Nieman LK. Neuroendocrine ACTH-producing tumor of the thymus--experience with 12 patients over 25 years. J Clin Endocrinol Metab. 2012 Jul;97(7):2223-30. doi: 10.1210/jc.2011-3355. Epub 2012 Apr 16. PubMed PMID: 22508705; PubMed Central PMCID: PMC3387392.
Boyce AM, Chong WH, Shawker TH, Pinto PA, Linehan WM, Bhattacharryya N, Merino MJ, Singer FR, Collins MT. Characterization and management of testicular pathology in McCune-Albright syndrome. J Clin Endocrinol Metab. 2012 Sep;97(9):E1782-90. doi: 10.1210/jc.2012-1791. Epub 2012 Jun 28. PubMed PMID: 22745241; PubMed Central PMCID: PMC3431566.
Boyce AM, Glover M, Kelly MH, Brillante BA, Butman JA, Fitzgibbon EJ, Brewer CC, Zalewski CK, Cutler Peck CM, Kim HJ, Collins MT. Optic neuropathy in McCune-Albright syndrome: effects of early diagnosis and treatment of growth hormone excess. J Clin Endocrinol Metab. 2013 Jan;98(1):E126-34. doi: 10.1210/jc.2012-2111. Epub 2012 Oct 23. PubMed PMID: 23093488; PubMed Central PMCID: PMC3537097.
Tosi LL, O"Connell M, Boyce AM. Sexual Dimorphism in Metabolic Bone Disorders. Bethesda, MD: National Institutes of Health Office of Research on Women’s Health; 2013. module for online continuing medical education course entitled "The Influence of Sex and Gender on Disease Expression and Treatment".
Boyce AM, Shawker TH, Hill SC, Choyke PL, Hill MC, James R, Yovetich NA, Collins MT, Gafni RI. Ultrasound is superior to computed tomography for assessment of medullary nephrocalcinosis in hypoparathyroidism. J Clin Endocrinol Metab. 2013 Mar;98(3):989-94. doi: 10.1210/jc.2012-2747. Epub 2013 Jan 24. PubMed PMID: 23348401; PubMed Central PMCID: PMC3590469.
Boyce AM, Bhattacharyya N, Collins MT. Fibrous dysplasia and fibroblast growth factor-23 regulation. Curr Osteoporos Rep. 2013 Jun;11(2):65-71. doi: 10.1007/s11914-013-0144-5. Review. PubMed PMID: 23532406; PubMed Central PMCID: PMC3669677.
Chong WH, Andreopoulou P, Chen CC, Reynolds J, Guthrie L, Kelly M, Gafni RI, Bhattacharyya N, Boyce AM, El-Maouche D, Crespo DO, Sherry R, Chang R, Wodajo FM, Kletter GB, Dwyer A, Collins MT. Tumor localization and biochemical response to cure in tumor-induced osteomalacia. J Bone Miner Res. 2013 Jun;28(6):1386-98. doi: 10.1002/jbmr.1881. PubMed PMID: 23362135; PubMed Central PMCID: PMC3900247.
Akintoye SO, Boyce AM, Collins MT. Dental perspectives in fibrous dysplasia and McCune-Albright syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Sep;116(3):e149-55. doi: 10.1016/j.oooo.2013.05.023. PubMed PMID: 23953425; PubMed Central PMCID: PMC3851571.
Lim YH, Ovejero D, Sugarman JS, Deklotz CM, Maruri A, Eichenfield LF, Kelley PK, Jüppner H, Gottschalk M, Tifft CJ, Gafni RI, Boyce AM, Cowen EW, Bhattacharyya N, Guthrie LC, Gahl WA, Golas G, Loring EC, Overton JD, Mane SM, Lifton RP, Levy ML, Collins MT, Choate KA. Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia. Hum Mol Genet. 2014 Jan 15;23(2):397-407. doi: 10.1093/hmg/ddt429. Epub 2013 Sep 4. PubMed PMID: 24006476; PubMed Central PMCID: PMC3869357.
Paul SM, Gabor LR, Rudzinski S, Giovanni D, Boyce AM, Kelly MR, Collins MT. Disease severity and functional factors associated with walking performance in polyostotic fibrous dysplasia. Bone. 2014 Mar;60:41-7. doi: 10.1016/j.bone.2013.11.022. Epub 2013 Dec 4. PubMed PMID: 24316419; PubMed Central PMCID: PMC3985279.
Wang HD, Boyce AM, Tsai JY, Gafni RI, Farley FA, Kasa-Vubu JZ, Molinolo AA, Collins MT. Effects of denosumab treatment and discontinuation on human growth plates. J Clin Endocrinol Metab. 2014 Mar;99(3):891-7. doi: 10.1210/jc.2013-3081. Epub 2014 Jan 1. PubMed PMID: 24423331; PubMed Central PMCID: PMC3942242.
Ippolito E, Farsetti P, Boyce AM, Corsi A, De Maio F, Collins MT. Radiographic classification of coronal plane femoral deformities in polyostotic fibrous dysplasia. Clin Orthop Relat Res. 2014 May;472(5):1558-67. doi: 10.1007/s11999-013-3380-1. Epub 2013 Nov 19. PubMed PMID: 24249535; PubMed Central PMCID: PMC3971252.
Boyce AM, Tosi LL, Paul SM. Bisphosphonate treatment for children with disabling conditions. PM R. 2014 May;6(5):427-36. doi: 10.1016/j.pmrj.2013.10.009. Epub 2013 Dec 22. Review. PubMed PMID: 24368091; PubMed Central PMCID: PMC4037384.
Salenave S, Boyce AM, Collins MT, Chanson P. Acromegaly and McCune-Albright syndrome. J Clin Endocrinol Metab. 2014 Jun;99(6):1955-69. doi: 10.1210/jc.2013-3826. Epub 2014 Feb 11. Review. PubMed PMID: 24517150; PubMed Central PMCID: PMC4037730.
Foster BL, Ramnitz MS, Gafni RI, Burke AB, Boyce AM, Lee JS, Wright JT, Akintoye SO, Somerman MJ, Collins MT. Rare bone diseases and their dental, oral, and craniofacial manifestations. J Dent Res. 2014 Jul;93(7 Suppl):7S-19S. doi: 10.1177/0022034514529150. Epub 2014 Apr 3. Review. PubMed PMID: 24700690; PubMed Central PMCID: PMC4107543.
Pichard DC, Boyce AM, Collins MT, Cowen EW. Oral pigmentation in McCune-Albright syndrome. JAMA Dermatol. 2014 Jul;150(7):760-3. doi: 10.1001/jamadermatol.2014.184. PubMed PMID: 24671640; PubMed Central PMCID: PMC4933654.
Boyce AM, Kelly MH, Brillante BA, Kushner H, Wientroub S, Riminucci M, Bianco P, Robey PG, Collins MT. A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 2014 Nov;99(11):4133-40. doi: 10.1210/jc.2014-1371. Epub 2014 Jul 17. PubMed PMID: 25033066; PubMed Central PMCID: PMC4223439.
Gafni RI, Alter CA, Bauer AA, Boyce AM, DeBoer M, Huang SA, LaFranchi SH, Lekarev O, Miller BS, Palma Sista PA, Silverman L, Stratakis CA, Thornton PS, Weinzimer SA. Pediatric ESAP 2015-2016: Pediatric Endocrine Self-Assessment Program. The Endocrine Society. 2015.
Gafni RI, Bauer AJ, DeBoer M, Boyce AM, Habiby RL, Lekarev O, Miller BS, Palma Sista PA, Peske LM, Silverman L, Thornton PS. Pediatric ESAP 2017-2018: Pediatric Endocrine Self-Assessment Program. The Endocrine Society. 2015.
Boyce AM, Tosi LL. Rickets/Osteomalacia. In: The 5-Minute Pediatric Consult Standard, 7th ed. 2015; :794-795.
Leet AI, Boyce AM, Ibrahim KA, Wientroub S, Kushner H, Collins MT. Bone-Grafting in Polyostotic Fibrous Dysplasia. J Bone Joint Surg Am. 2016 Feb 3;98(3):211-9. doi: 10.2106/JBJS.O.00547. PubMed PMID: 26842411; PubMed Central PMCID: PMC4732545.
Boyce AM, Burke A, Cutler Peck C, DuFresne CR, Lee JS, Collins MT. Surgical Management of Polyostotic Craniofacial Fibrous Dysplasia: Long-Term Outcomes and Predictors for Postoperative Regrowth. Plast Reconstr Surg. 2016 Jun;137(6):1833-1839. doi: 10.1097/PRS.0000000000002151. PubMed PMID: 27219238; PubMed Central PMCID: PMC5653228.
Burke AB, Boyce AM, Collins MT. Fibrous Dysplasia: Management of the Optic Canal. Plast Reconstr Surg. 2016 Jun;137(6):1060e-1061e. doi: 10.1097/PRS.0000000000002210. PubMed PMID: 26890512; PubMed Central PMCID: PMC4879004.
Robinson C, Collins MT, Boyce AM. Fibrous Dysplasia/McCune-Albright Syndrome: Clinical and Translational Perspectives. Curr Osteoporos Rep. 2016 Oct;14(5):178-86. doi: 10.1007/s11914-016-0317-0. Review. PubMed PMID: 27492469; PubMed Central PMCID: PMC5035212.
Metwally T, Burke A, Tsai JY, Collins MT, Boyce AM. Fibrous Dysplasia and Medication-Related Osteonecrosis of the Jaw. J Oral Maxillofac Surg. 2016 Oct;74(10):1983-99. doi: 10.1016/j.joms.2016.04.001. Epub 2016 Apr 7. PubMed PMID: 27137436; PubMed Central PMCID: PMC5039058.
Estrada A, Boyce AM, Brillante BA, Guthrie LC, Gafni RI, Collins MT. Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome. Eur J Endocrinol. 2016 Nov;175(5):477-483. doi: 10.1530/EJE-16-0526. Epub 2016 Aug 25. PubMed PMID: 27562402; PubMed Central PMCID: PMC5066167.
Ovejero D, Lim YH, Boyce AM, Gafni RI, McCarthy E, Nguyen TA, Eichenfield LF, DeKlotz CM, Guthrie LC, Tosi LL, Thornton PS, Choate KA, Collins MT. Cutaneous skeletal hypophosphatemia syndrome: clinical spectrum, natural history, and treatment. Osteoporos Int. 2016 Dec;27(12):3615-3626. doi: 10.1007/s00198-016-3702-8. Epub 2016 Aug 6. Review. PubMed PMID: 27497815; PubMed Central PMCID: PMC6908308.
Boyce AM, Collins MT, Tosi LL, Gafni RI. A Subtrochanteric Femoral Stress Fracture following Bisphosphonate Treatment in an Adolescent Girl. Horm Res Paediatr. 2017;87(1):69-72. doi: 10.1159/000447425. Epub 2016 Jul 6. PubMed PMID: 27379824; PubMed Central PMCID: PMC5218986.
Mete O, Boyce AM, Stratakis C, Weinstein L. McCune-Albright Syndrome. World Health Organization Classification of Tumours of the Endocrine Organs, 4th ed. 2017.
Davis RJ, Boyce AM, Mydlarz WK. A Toddler With Nasal Congestion and a Limp. JAMA Otolaryngol Head Neck Surg. 2017 Feb 1;143(2):191-192. doi: 10.1001/jamaoto.2016.2392. PubMed PMID: 27737440.
Wood LD, Noë M, Hackeng W, Brosens LA, Bhaijee F, Debeljak M, Yu J, Suenaga M, Singhi AD, Zaheer A, Boyce A, Robinson C, Eshleman JR, Goggins MG, Hruban RH, Collins MT, Lennon AM, Montgomery EA. Patients with McCune-Albright syndrome have a broad spectrum of abnormalities in the gastrointestinal tract and pancreas. Virchows Arch. 2017 Apr;470(4):391-400. doi: 10.1007/s00428-017-2086-2. Epub 2017 Feb 10. PubMed PMID: 28188442; PubMed Central PMCID: PMC5376511.
Boyce AM. Denosumab: an Emerging Therapy in Pediatric Bone Disorders. Curr Osteoporos Rep. 2017 Aug;15(4):283-292. doi: 10.1007/s11914-017-0380-1. Review. PubMed PMID: 28643220; PubMed Central PMCID: PMC5554707.
Burke AB, Collins MT, Boyce AM. Fibrous dysplasia of bone: craniofacial and dental implications. Oral Dis. 2017 Sep;23(6):697-708. doi: 10.1111/odi.12563. Epub 2016 Sep 1. Review. PubMed PMID: 27493082; PubMed Central PMCID: PMC5292317.
Boyce AM, Turner A, Watts L, Forestier-Zhang L, Underhill A, Pinedo-Villanueva R, Monsell F, Tessaris D, Burren C, Masi L, Hamdy N, Brandi ML, Chapurlat R, Collins MT, Javaid MK. Improving patient outcomes in fibrous dysplasia/McCune-Albright syndrome: an international multidisciplinary workshop to inform an international partnership. Arch Osteoporos. 2017 Dec;12(1):21. doi: 10.1007/s11657-016-0271-6. Epub 2017 Feb 27. PubMed PMID: 28243882; PubMed Central PMCID: PMC5653227.
Majoor BC, Boyce AM, Bovée JV, Smit VT, Collins MT, Cleton-Jansen AM, Dekkers OM, Hamdy NA, Dijkstra PS, Appelman-Dijkstra NM. Increased Risk of Breast Cancer at a Young Age in Women with Fibrous Dysplasia. J Bone Miner Res. 2018 Jan;33(1):84-90. doi: 10.1002/jbmr.3286. Epub 2017 Sep 20. PubMed PMID: 28856726.
Robinson C, Boyce AM, Estrada A, Kleiner DE, Mathew R, Stanton R, Frangoul H, Collins MT. Bone marrow failure and extramedullary hematopoiesis in McCune-Albright syndrome. Osteoporos Int. 2018 Jan;29(1):237-241. doi: 10.1007/s00198-017-4217-7. Epub 2017 Oct 25. PubMed PMID: 29071359; PubMed Central PMCID: PMC6983319.
Collins MT, Boyce AM, Riminucci M. Fibrous Dysplasia. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 9th ed. 2018; :839-847.
Boyce AM. The Bone Health History and Physical Examination in Adolescents. In: A Practical Approach to Adolescent Bone Health. 2018; :77-91.
Boyce AM, Brewer C, DeKlotz TR, Zalewski CK, King KA, Collins MT, Kim HJ. Association of Hearing Loss and Otologic Outcomes With Fibrous Dysplasia. JAMA Otolaryngol Head Neck Surg. 2018 Feb 1;144(2):102-107. doi: 10.1001/jamaoto.2017.2407. PubMed PMID: 29192304; PubMed Central PMCID: PMC5839293.
Pan KS, FitzGibbon EJ, Lee JS, Collins MT, Boyce AM. Letter to the Editor Regarding "Optical Coherence Tomography in the Management of Skull Base Fibrous Dysplasia with Optic Nerve Involvement". World Neurosurg. 2018 Jun;114:427-428. doi: 10.1016/j.wneu.2018.02.166. PubMed PMID: 29791994.
Tessaris D, Boyce AM, Zacharin M, Matarazzo P, Lala R, De Sanctis L, Collins MT. Growth hormone-Insulin-like growth factor 1 axis hyperactivity on bone fibrous dysplasia in McCune-Albright Syndrome. Clin Endocrinol (Oxf). 2018 Jul;89(1):56-64. doi: 10.1111/cen.13722. Epub 2018 May 17. PubMed PMID: 29672904.
Berglund JA, Tella SH, Tuthill KF, Kim L, Guthrie LC, Paul SM, Stanton R, Collins MT, Boyce AM. Scoliosis in Fibrous Dysplasia/McCune-Albright Syndrome: Factors Associated With Curve Progression and Effects of Bisphosphonates. J Bone Miner Res. 2018 Sep;33(9):1641-1648. doi: 10.1002/jbmr.3446. Epub 2018 May 22. PubMed PMID: 29669167.
Gafni RI, Langman CB, Guthrie LC, Brillante BA, James R, Yovetich NA, Boyce AM, Collins MT. Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. J Bone Miner Res. 2018 Oct;33(10):1741-1747. doi: 10.1002/jbmr.3480. Epub 2018 Jun 22. PubMed PMID: 29878514.
Pan KS, Heiss JD, Brown SM, Collins MT, Boyce AM. Chiari I Malformation and Basilar Invagination in Fibrous Dysplasia: Prevalence, Mechanisms, and Clinical Implications. J Bone Miner Res. 2018 Nov;33(11):1990-1998. doi: 10.1002/jbmr.3531. Epub 2018 Aug 3. PubMed PMID: 29924878; PubMed Central PMCID: PMC6218312.
Robinson C, Estrada A, Zaheer A, Singh VK, Wolfgang CL, Goggins MG, Hruban RH, Wood LD, Noë M, Montgomery EA, Guthrie LC, Lennon AM, Boyce AM, Collins MT. Clinical and Radiographic Gastrointestinal Abnormalities in McCune-Albright Syndrome. J Clin Endocrinol Metab. 2018 Nov 1;103(11):4293-4303. doi: 10.1210/jc.2018-01022. PubMed PMID: 30124968; PubMed Central PMCID: PMC6194803.
What would you like to do?