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Salem AK, Cannizzaro SM, Davies MC, Tendler SJ, Roberts CJ, Williams PM, Shakesheff KM. Synthesis and characterisation of a degradable poly(lactic acid)-poly(ethylene glycol) copolymer with biotinylated end groups. Biomacromolecules. 2001 Summer;2(2):575-80. doi: 10.1021/bm010030+. PubMed PMID: 11749223.
Salem AK, Stevens R, Pearson RG, Davies MC, Tendler SJ, Roberts CJ, Williams PM, Shakesheff KM. Interactions of 3T3 fibroblasts and endothelial cells with defined pore features. J Biomed Mater Res. 2002 Aug;61(2):212-7. doi: 10.1002/jbm.10195. PubMed PMID: 12007201.
Salem AK, Searson PC, Leong KW. Multifunctional nanorods for gene delivery. Nat Mater. 2003 Oct;2(10):668-71. doi: 10.1038/nmat974. Epub 2003 Sep 14. PubMed PMID: 12970757.
Sakhalkar HS, Dalal MK, Salem AK, Ansari R, Fu J, Kiani MF, Kurjiaka DT, Hanes J, Shakesheff KM, Goetz DJ. Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15895-900. doi: 10.1073/pnas.2631433100. Epub 2003 Dec 10. PubMed PMID: 14668435; PubMed Central PMCID: PMC307664.
Hultgren A, Tanase M, Felton EJ, Bhadriraju K, Salem AK, Chen CS, Reich DH. Optimization of yield in magnetic cell separations using nickel nanowires of different lengths. Biotechnol Prog. 2005 Mar-Apr;21(2):509-15. doi: 10.1021/bp049734w. PubMed PMID: 15801791.
Baman NK, Schneider GB, Terry TL, Zaharias R, Salem AK. Spatial control over cell attachment by partial solvent entrapment of poly lysine in microfluidic channels. Int J Nanomedicine. 2006;1(2):213-7. doi: 10.2147/nano.2006.1.2.213. PubMed PMID: 17722538; PubMed Central PMCID: PMC2426782.
Sinclair J, Salem AK. Rapid localized cell trapping on biodegradable polymers using cell surface derivatization and microfluidic networking. Biomaterials. 2006 Mar;27(9):2090-4. doi: 10.1016/j.biomaterials.2005.10.036. Epub 2005 Nov 22. PubMed PMID: 16307795.
Zhang XQ, Dahle CE, Baman NK, Rich N, Weiner GJ, Salem AK. Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles. J Immunother. 2007 Jul-Aug;30(5):469-78. doi: 10.1097/CJI.0b013e31802fd8c6. PubMed PMID: 17589287.
Zhang XQ, Intra J, Salem AK. Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery. Bioconjug Chem. 2007 Nov-Dec;18(6):2068-76. doi: 10.1021/bc070116l. Epub 2007 Sep 12. PubMed PMID: 17848077.
Pearce ME, Melanko JB, Salem AK. Multifunctional nanorods for biomedical applications. Pharm Res. 2007 Dec;24(12):2335-52. doi: 10.1007/s11095-007-9380-7. Epub 2007 Aug 8. Review. PubMed PMID: 17684708.
Zhang XQ, Dahle CE, Weiner GJ, Salem AK. A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles. J Pharm Sci. 2007 Dec;96(12):3283-92. doi: 10.1002/jps.20978. PubMed PMID: 17497736.
Zhang XQ, Intra J, Salem AK. Comparative study of poly (lactic-co-glycolic acid)-poly ethyleneimine-plasmid DNA microparticles prepared using double emulsion methods. J Microencapsul. 2008 Feb;25(1):1-12. doi: 10.1080/02652040701659347. PubMed PMID: 18188727.
Clapper JD, Pearce ME, Guymon CA, Salem AK. Biotinylated biodegradable nanotemplated hydrogel networks for cell interactive applications. Biomacromolecules. 2008 Apr;9(4):1188-94. doi: 10.1021/bm701176j. Epub 2008 Feb 29. PubMed PMID: 18307307.
Pearce ME, Mai HQ, Lee N, Larsen SC, Salem AK. Silicalite nanoparticles that promote transgene expression. Nanotechnology. 2008 Apr 30;19(17):175103. doi: 10.1088/0957-4484/19/17/175103. Epub 2008 Mar 25. PubMed PMID: 21825661.
Intra J, Glasgow JM, Mai HQ, Salem AK. Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals. J Control Release. 2008 May 8;127(3):280-7. doi: 10.1016/j.jconrel.2008.02.001. Epub 2008 Feb 11. PubMed PMID: 18342975.
Abbas AO, Donovan MD, Salem AK. Formulating poly(lactide-co-glycolide) particles for plasmid DNA delivery. J Pharm Sci. 2008 Jul;97(7):2448-61. doi: 10.1002/jps.21215. Review. PubMed PMID: 17918737.
Intra J, Salem AK. Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo. J Control Release. 2008 Sep 10;130(2):129-38. doi: 10.1016/j.jconrel.2008.04.014. Epub 2008 Apr 24. PubMed PMID: 18538436; PubMed Central PMCID: PMC2603176.
Salem AK, Weiner GJ. CpG oligonucleotides as immunotherapeutic adjuvants: innovative applications and delivery strategies. Adv Drug Deliv Rev. 2009 Mar 28;61(3):193-4. doi: 10.1016/j.addr.2008.12.003. Epub 2009 Jan 7. PubMed PMID: 19166888; PubMed Central PMCID: PMC2667912.
Krishnamachari Y, Salem AK. Innovative strategies for co-delivering antigens and CpG oligonucleotides. Adv Drug Deliv Rev. 2009 Mar 28;61(3):205-17. doi: 10.1016/j.addr.2008.12.013. Epub 2009 Jan 19. Review. PubMed PMID: 19272328; PubMed Central PMCID: PMC2656598.
Goforth R, Salem AK, Zhu X, Miles S, Zhang XQ, Lee JH, Sandler AD. Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma. Cancer Immunol Immunother. 2009 Apr;58(4):517-30. doi: 10.1007/s00262-008-0574-6. Epub 2008 Aug 22. PubMed PMID: 18719913; PubMed Central PMCID: PMC11030463.
Petushkov A, Intra J, Graham JB, Larsen SC, Salem AK. Effect of crystal size and surface functionalization on the cytotoxicity of silicalite-1 nanoparticles. Chem Res Toxicol. 2009 Jul;22(7):1359-68. doi: 10.1021/tx900153k. PubMed PMID: 19580308.
Intra J, Salem AK. Fabrication, characterization and in vitro evaluation of poly(D,L-lactide-co-glycolide) microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in nonviral gene delivery. J Pharm Sci. 2010 Jan;99(1):368-84. doi: 10.1002/jps.21840. PubMed PMID: 19670295; PubMed Central PMCID: PMC2882054.
Intra J, Zhang XQ, Williams RL, Zhu X, Sandler AD, Salem AK. Immunostimulatory sutures that treat local disease recurrence following primary tumor resection. Biomed Mater. 2011 Feb;6(1):011001. doi: 10.1088/1748-6041/6/1/011001. Epub 2011 Jan 5. PubMed PMID: 21206000; PubMed Central PMCID: PMC4347863.
Krishnamachari Y, Geary SM, Lemke CD, Salem AK. Nanoparticle delivery systems in cancer vaccines. Pharm Res. 2011 Feb;28(2):215-36. doi: 10.1007/s11095-010-0241-4. Epub 2010 Aug 19. Review. PubMed PMID: 20721603; PubMed Central PMCID: PMC3559243.
Hong L, Krishnamachari Y, Seabold D, Joshi V, Schneider G, Salem AK. Intracellular release of 17-β estradiol from cationic polyamidoamine dendrimer surface-modified poly (lactic-co-glycolic acid) microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Eng Part C Methods. 2011 Mar;17(3):319-25. doi: 10.1089/ten.TEC.2010.0388. Epub 2010 Nov 22. PubMed PMID: 20883116; PubMed Central PMCID: PMC3045071.
Lemke CD, Graham JB, Lubaroff DM, Salem AK. Development of an MHC class I L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8+ T cells in the mouse. Prostate Cancer Prostatic Dis. 2011 Jun;14(2):118-21. doi: 10.1038/pcan.2010.57. Epub 2011 Jan 25. PubMed PMID: 21263453; PubMed Central PMCID: PMC3094480.
Intra J, Salem AK. Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells. J Drug Target. 2011 Jul;19(6):393-408. doi: 10.3109/1061186X.2010.504263. Epub 2010 Aug 3. PubMed PMID: 20681752; PubMed Central PMCID: PMC5258116.
Geary SM, Lemke CD, Lubaroff DM, Salem AK. Tumor immunotherapy using adenovirus vaccines in combination with intratumoral doses of CpG ODN. Cancer Immunol Immunother. 2011 Sep;60(9):1309-17. doi: 10.1007/s00262-011-1038-y. Epub 2011 May 28. PubMed PMID: 21626029; PubMed Central PMCID: PMC4358758.
Santillan DA, Rai KK, Santillan MK, Krishnamachari Y, Salem AK, Hunter SK. Efficacy of polymeric encapsulated C5a peptidase-based group B streptococcus vaccines in a murine model. Am J Obstet Gynecol. 2011 Sep;205(3):249.e1-8. doi: 10.1016/j.ajog.2011.06.024. Epub 2011 Jun 15. PubMed PMID: 21802065; PubMed Central PMCID: PMC3213321.
Lemke CD, Graham JB, Geary SM, Zamba G, Lubaroff DM, Salem AK. Chitosan is a surprising negative modulator of cytotoxic CD8+ T cell responses elicited by adenovirus cancer vaccines. Mol Pharm. 2011 Oct 3;8(5):1652-61. doi: 10.1021/mp100464y. Epub 2011 Aug 9. PubMed PMID: 21780831; PubMed Central PMCID: PMC3562499.
Yoo J, D'Mello SR, Graf T, Salem AK, Bowden NB. Synthesis of the first poly(diaminosulfide)s and an investigation of their applications as drug delivery vehicles. Macromolecules. 2012 Jan 24;45(2):688-697. doi: 10.1021/ma2023167. PubMed PMID: 22347726; PubMed Central PMCID: PMC3280910.
Yoo J, Kuruvilla DJ, D'Mello SR, Salem AK, Bowden NB. New class of biodegradable polymers formed from reactions of an inorganic functional group. Macromolecules. 2012 Mar 13;45(5):2292-2300. doi: 10.1021/ma300190b. Epub 2012 Feb 21. PubMed PMID: 22454554; PubMed Central PMCID: PMC3311917.
Rosevear HM, Krishnamachari Y, Ariza CA, Mallapragada SK, Salem AK, Griffith TS, De Young BR, Wald M. Effect of combined locally delivered growth factors and systemic sildenafil citrate on microrecanalization in biodegradable conduit for vas deferens reconstruction. Urology. 2012 Apr;79(4):967.e1-4. doi: 10.1016/j.urology.2011.11.030. Epub 2012 Jan 27. PubMed PMID: 22285175.
Hong L, Wei N, Joshi V, Yu Y, Kim N, Krishnamachari Y, Zhang Q, Salem AK. Effects of glucocorticoid receptor small interfering RNA delivered using poly lactic-co-glycolic acid microparticles on proliferation and differentiation capabilities of human mesenchymal stromal cells. Tissue Eng Part A. 2012 Apr;18(7-8):775-84. doi: 10.1089/ten.TEA.2011.0432. Epub 2012 Jan 17. PubMed PMID: 21988716; PubMed Central PMCID: PMC3313605.
Salem AK, Patil SD, Burgess DJ. Recent progress in non-viral nucleic acids delivery. Int J Pharm. 2012 May 1;427(1):1-2. doi: 10.1016/j.ijpharm.2011.11.029. Epub 2011 Nov 28. PubMed PMID: 22143087.
Kim N, Jiang D, Jacobi AM, Lennox KA, Rose SD, Behlke MA, Salem AK. Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA. Int J Pharm. 2012 May 1;427(1):123-33. doi: 10.1016/j.ijpharm.2011.08.014. Epub 2011 Aug 12. PubMed PMID: 21864664; PubMed Central PMCID: PMC3237934.
Jiang D, Salem AK. Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments. Int J Pharm. 2012 May 1;427(1):71-9. doi: 10.1016/j.ijpharm.2011.10.032. Epub 2011 Oct 21. PubMed PMID: 22037445; PubMed Central PMCID: PMC3295901.
Krishnamurthy S, Behlke MA, Ramachandran S, Salem AK, McCray PB Jr, Davidson BL. Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia. Mol Ther Nucleic Acids. 2012 Aug 28;1(8):e41. doi: 10.1038/mtna.2012.36. PubMed PMID: 23344182; PubMed Central PMCID: PMC3437804.
Joshi VB, Geary SM, Salem AK. Biodegradable particles as vaccine delivery systems: size matters. AAPS J. 2013 Jan;15(1):85-94. doi: 10.1208/s12248-012-9418-6. Epub 2012 Oct 10. PubMed PMID: 23054976; PubMed Central PMCID: PMC3535111.
Joshi VB, Geary SM, Carrillo-Conde BR, Narasimhan B, Salem AK. Characterizing the antitumor response in mice treated with antigen-loaded polyanhydride microparticles. Acta Biomater. 2013 Mar;9(3):5583-9. doi: 10.1016/j.actbio.2012.11.001. Epub 2012 Nov 12. PubMed PMID: 23153760; PubMed Central PMCID: PMC3562412.
Lemke CD, Geary SM, Joshi VB, Salem AK. Antigen-coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations. Biomaterials. 2013 Mar;34(10):2524-9. doi: 10.1016/j.biomaterials.2012.12.030. Epub 2013 Jan 11. PubMed PMID: 23312902; PubMed Central PMCID: PMC3557532.
Geary SM, Lemke CD, Lubaroff DM, Salem AK. Proposed mechanisms of action for prostate cancer vaccines. Nat Rev Urol. 2013 Mar;10(3):149-60. doi: 10.1038/nrurol.2013.8. Epub 2013 Feb 12. Review. PubMed PMID: 23399727; PubMed Central PMCID: PMC4358823.
Geary SM, Salem AK. Prostate cancer vaccines: Update on clinical development. Oncoimmunology. 2013 May 1;2(5):e24523. doi: 10.4161/onci.24523. Epub 2013 Apr 29. PubMed PMID: 23762812; PubMed Central PMCID: PMC3667918.
Geary SM, Lemke CD, Lubaroff DM, Salem AK. The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a tumor model system. PLoS One. 2013;8(6):e67904. doi: 10.1371/journal.pone.0067904. Print 2013. PubMed PMID: 23840786; PubMed Central PMCID: PMC3695864.
Wongrakpanich A, Joshi VB, Salem AK. Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells. Pharm Dev Technol. 2013 Sep-Oct;18(5):1255-8. doi: 10.3109/10837450.2011.649856. Epub 2012 Jan 12. PubMed PMID: 22235917; PubMed Central PMCID: PMC3638068.
Worthington KL, Adamcakova-Dodd A, Wongrakpanich A, Mudunkotuwa IA, Mapuskar KA, Joshi VB, Allan Guymon C, Spitz DR, Grassian VH, Thorne PS, Salem AK. Chitosan coating of copper nanoparticles reduces in vitro toxicity and increases inflammation in the lung. Nanotechnology. 2013 Oct 4;24(39):395101. doi: 10.1088/0957-4484/24/39/395101. Epub 2013 Sep 5. PubMed PMID: 24008224; PubMed Central PMCID: PMC3816956.
Wei N, Yu Y, Joshi V, Schmidt T, Qian F, Salem AK, Stanford C, Hong L. Glucocorticoid receptor antagonist and siRNA prevent senescence of human bone marrow mesenchymal stromal cells in vitro. Cell Tissue Res. 2013 Nov;354(2):461-70. doi: 10.1007/s00441-013-1700-0. Epub 2013 Aug 21. PubMed PMID: 23963647; PubMed Central PMCID: PMC5001800.
Joshi VB, Geary SM, Salem AK. Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses. Hum Vaccin Immunother. 2013 Dec;9(12):2584-90. doi: 10.4161/hv.26136. Epub 2013 Aug 26. Review. PubMed PMID: 23978910; PubMed Central PMCID: PMC4162053.
D'Mello SR, Yoo J, Bowden NB, Salem AK. Microparticles prepared from sulfenamide-based polymers. J Microencapsul. 2014;31(2):137-46. doi: 10.3109/02652048.2013.814728. Epub 2013 Jul 18. PubMed PMID: 23862723; PubMed Central PMCID: PMC4295722.
Geary SM, Salem AK. Exploiting the tumor phenotype using biodegradable submicron carriers of chemotherapeutic drugs. Crit Rev Oncog. 2014;19(3-4):269-80. doi: 10.1615/critrevoncog.2014011518. Review. PubMed PMID: 25271435; PubMed Central PMCID: PMC4183966.
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