My Bibliography

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Cabezas M, Comellas A, Ramón Gómez J, López Grillo L, Casal H, Carrillo N, Camero R, Castillo R. [Comparison of the sensitivity and specificity of the electrocardiography criteria for left ventricular hypertrophy according to the methods of Romhilt-Estes, Sokolow-Lyon, Cornell and Rodríguez Padial]. Rev Esp Cardiol. 1997 Jan;50(1):31-5. doi: 10.1016/s0300-8932(97)73173-7. PubMed PMID: 9053944.

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Saldías FJ, Comellas A, Guerrero C, Ridge KM, Rutschman DH, Sznajder JI. Time course of active and passive liquid and solute movement in the isolated perfused rat lung model. J Appl Physiol (1985). 1998 Oct;85(4):1572-7. doi: 10.1152/jappl.1998.85.4.1572. PubMed PMID: 9760355.

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Pesce L, Tristano S, Friedman E, Comellas A, Marcano H, Sanchez de León R. Effect of Fenoterol on PAF-induced lung edema in isolated and perfused rabbit lungs. Respir Physiol. 1998 Nov;114(2):153-60. doi: 10.1016/s0034-5687(98)00082-6. PubMed PMID: 9865589.

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D'Suze G, Comellas A, Pesce L, Sevcik C, Sanchez-de-León R. Tityus discrepans venom produces a respiratory distress syndrome in rabbits through an indirect mechanism. Toxicon. 1999 Jan;37(1):173-80. doi: 10.1016/s0041-0101(98)00180-9. PubMed PMID: 9920489.

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Lecuona E, Saldías F, Comellas A, Ridge K, Guerrero C, Sznajder JI. Ventilator-associated lung injury decreases lung ability to clear edema in rats. Am J Respir Crit Care Med. 1999 Feb;159(2):603-9. doi: 10.1164/ajrccm.159.2.9805050. PubMed PMID: 9927379.

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Saldías FJ, Lecuona E, Comellas AP, Ridge KM, Sznajder JI. Dopamine restores lung ability to clear edema in rats exposed to hyperoxia. Am J Respir Crit Care Med. 1999 Feb;159(2):626-33. doi: 10.1164/ajrccm.159.2.9805016. PubMed PMID: 9927383.

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Comellas A, Tristano S, Pesce L, Friedman E, Marcano H, Sánchez de León R. Effect of platelet activating factor (PAF) on pulmonary circulation in isolated rabbit lung. J Physiol Biochem. 1999 Mar;55(1):1-6. PubMed PMID: 10494654.

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Saldías FJ, Comellas A, Ridge KM, Lecuona E, Sznajder JI. Isoproterenol improves ability of lung to clear edema in rats exposed to hyperoxia. J Appl Physiol (1985). 1999 Jul;87(1):30-5. doi: 10.1152/jappl.1999.87.1.30. PubMed PMID: 10409555.

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Lecuona E, Saldías F, Comellas A, Ridge K, Guerrero C, Sznajder JI. Ventilator-associated lung injury decreases lung ability to clear edema and downregulates alveolar epithelial cell Na,K-adenosine triphosphatase function. Chest. 1999 Jul;116(1 Suppl):29S-30S. doi: 10.1378/chest.116.suppl_1.29s. PubMed PMID: 10424573.

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Friedman E, Novoa E, Crespo A, Marcano H, Pesce L, Comellas A, Sánchez de León R. Effect of hydrocortisone on platelet activating factor induced lung edema in isolated rabbit lungs. Respir Physiol. 2000 Mar;120(1):61-9. doi: 10.1016/s0034-5687(00)00093-1. PubMed PMID: 10786645.

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Saldías FJ, Lecuona E, Comellas AP, Ridge KM, Rutschman DH, Sznajder JI. beta-adrenergic stimulation restores rat lung ability to clear edema in ventilator-associated lung injury. Am J Respir Crit Care Med. 2000 Jul;162(1):282-7. doi: 10.1164/ajrccm.162.1.9809058. PubMed PMID: 10903255.

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Pesce L, Guerrero C, Comellas A, Ridge KM, Sznajder JI. beta-agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways. FEBS Lett. 2000 Dec 15;486(3):310-4. doi: 10.1016/s0014-5793(00)02298-5. PubMed PMID: 11119725.

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Azzam ZS, Saldias FJ, Comellas A, Ridge KM, Rutschman DH, Sznajder JI. Catecholamines increase lung edema clearance in rats with increased left atrial pressure. J Appl Physiol (1985). 2001 Mar;90(3):1088-94. doi: 10.1152/jappl.2001.90.3.1088. PubMed PMID: 11181624.

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Saldías FJ, Comellas AP, Pesce L, Lecuona E, Sznajder JI. Dopamine increases lung liquid clearance during mechanical ventilation. Am J Physiol Lung Cell Mol Physiol. 2002 Jul;283(1):L136-43. doi: 10.1152/ajplung.00089.2000. PubMed PMID: 12060570.

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Comellas AP, Pesce LM, Azzam Z, Saldías FJ, Sznajder JI. Scorpion venom decreases lung liquid clearance in rats. Am J Respir Crit Care Med. 2003 Apr 15;167(8):1064-7. doi: 10.1164/rccm.200207-688OC. Epub 2003 Jan 24. PubMed PMID: 12684245.

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Pesce L, Comellas A, Sznajder JI. Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k. Am J Physiol Lung Cell Mol Physiol. 2003 Oct;285(4):L802-7. doi: 10.1152/ajplung.00266.2002. Epub 2003 Apr 18. PubMed PMID: 12704019.

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Upadhyay D, Lecuona E, Comellas A, Kamp DW, Sznajder JI. Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway. FEBS Lett. 2003 Jun 19;545(2-3):173-6. doi: 10.1016/s0014-5793(03)00527-1. PubMed PMID: 12804770.

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Sam S, Corbridge TC, Mokhlesi B, Comellas AP, Molitch ME. Cortisol levels and mortality in severe sepsis. Clin Endocrinol (Oxf). 2004 Jan;60(1):29-35. doi: 10.1111/j.1365-2265.2004.01923.x. PubMed PMID: 14678284.

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Azzam ZS, Adir Y, Crespo A, Comellas A, Lecuona E, Dada LA, Krivoy N, Rutschman DH, Sznajder JI, Ridge KM. Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity. Am J Respir Crit Care Med. 2004 Oct 1;170(7):730-6. doi: 10.1164/rccm.200308-1127OC. Epub 2004 Jul 15. PubMed PMID: 15256395.

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Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI. Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system. Circ Res. 2006 May 26;98(10):1314-22. doi: 10.1161/01.RES.0000222418.99976.1d. Epub 2006 Apr 13. PubMed PMID: 16614303.

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Comellas AP, Briva A, Dada LA, Butti ML, Trejo HE, Yshii C, Azzam ZS, Litvan J, Chen J, Lecuona E, Pesce LM, Yanagisawa M, Sznajder JI. Endothelin-1 impairs alveolar epithelial function via endothelial ETB receptor. Am J Respir Crit Care Med. 2009 Jan 15;179(2):113-22. doi: 10.1164/rccm.200804-540OC. Epub 2008 Oct 23. PubMed PMID: 18948426; PubMed Central PMCID: PMC2633058.

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Comellas AP, Briva A. Role of endothelin-1 in acute lung injury. Transl Res. 2009 Jun;153(6):263-71. doi: 10.1016/j.trsl.2009.02.007. Epub 2009 Mar 20. Review. PubMed PMID: 19446279; PubMed Central PMCID: PMC3046772.

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Peter Y, Comellas A, Levantini E, Ingenito EP, Shapiro SD. Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: implications for non-small cell lung cancer tumor colonization. Mol Carcinog. 2009 Jun;48(6):488-97. doi: 10.1002/mc.20485. PubMed PMID: 18942115; PubMed Central PMCID: PMC2763303.

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Lecuona E, Minin A, Trejo HE, Chen J, Comellas AP, Sun H, Grillo D, Nekrasova OE, Welch LC, Szleifer I, Gelfand VI, Sznajder JI. Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells. J Cell Sci. 2009 Nov 1;122(Pt 21):3915-22. doi: 10.1242/jcs.046953. Epub 2009 Oct 6. PubMed PMID: 19808891; PubMed Central PMCID: PMC2773192.

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Comellas AP, Kelly AM, Trejo HE, Briva A, Lee J, Sznajder JI, Dada LA. Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process mediated by the action of Akt. J Cell Sci. 2010 Apr 15;123(Pt 8):1343-51. doi: 10.1242/jcs.066464. Epub 2010 Mar 23. PubMed PMID: 20332111; PubMed Central PMCID: PMC2848117.

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Caraballo JC, Yshii C, Butti ML, Westphal W, Borcherding JA, Allamargot C, Comellas AP. Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC-ζ and PP2A pathway. Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L569-78. doi: 10.1152/ajplung.00109.2010. Epub 2011 Jan 21. PubMed PMID: 21257729; PubMed Central PMCID: PMC3075095.

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Caraballo JC, Yshii C, Westphal W, Moninger T, Comellas AP. Ambient particulate matter affects occludin distribution and increases alveolar transepithelial electrical conductance. Respirology. 2011 Feb;16(2):340-9. doi: 10.1111/j.1440-1843.2010.01910.x. PubMed PMID: 21122029; PubMed Central PMCID: PMC3625061.

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Pesce L, Bizhanova A, Caraballo JC, Westphal W, Butti ML, Comellas A, Kopp P. TSH regulates pendrin membrane abundance and enhances iodide efflux in thyroid cells. Endocrinology. 2012 Jan;153(1):512-21. doi: 10.1210/en.2011-1548. Epub 2011 Nov 22. PubMed PMID: 22109890; PubMed Central PMCID: PMC3249672.

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Li X, Comellas AP, Karp PH, Ernst SE, Moninger TO, Gansemer ND, Taft PJ, Pezzulo AA, Rector MV, Rossen N, Stoltz DA, McCray PB Jr, Welsh MJ, Zabner J. CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia. Am J Physiol Lung Cell Mol Physiol. 2012 Jul;303(2):L152-60. doi: 10.1152/ajplung.00116.2012. Epub 2012 May 25. PubMed PMID: 22637155; PubMed Central PMCID: PMC3404631.

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Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, Rennard S, Litonjua A, Qiu W, Beaty TH, Crapo JD, Riley JH, Tal-Singer R, Silverman EK. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1238-47. doi: 10.1164/rccm.201206-1013OC. Epub 2012 Nov 9. PubMed PMID: 23144326; PubMed Central PMCID: PMC3622441.

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Caraballo JC, Borcherding J, Thorne PS, Comellas AP. Protein kinase C-ζ mediates lung injury induced by diesel exhaust particles. Am J Respir Cell Mol Biol. 2013 Mar;48(3):306-13. doi: 10.1165/rcmb.2012-0056OC. Epub 2012 Dec 6. PubMed PMID: 23221045; PubMed Central PMCID: PMC3604088.

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Borcherding JA, Chen H, Caraballo JC, Baltrusaitis J, Pezzulo AA, Zabner J, Grassian VH, Comellas AP. Coal fly ash impairs airway antimicrobial peptides and increases bacterial growth. PLoS One. 2013;8(2):e57673. doi: 10.1371/journal.pone.0057673. Epub 2013 Feb 28. PubMed PMID: 23469047; PubMed Central PMCID: PMC3585163.

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Monick MM, Baltrusaitis J, Powers LS, Borcherding JA, Caraballo JC, Mudunkotuwa I, Peate DW, Walters K, Thompson JM, Grassian VH, Gudmundsson G, Comellas AP. Effects of Eyjafjallajökull volcanic ash on innate immune system responses and bacterial growth in vitro. Environ Health Perspect. 2013 Jun;121(6):691-8. doi: 10.1289/ehp.1206004. Epub 2013 Mar 11. PubMed PMID: 23478268; PubMed Central PMCID: PMC3672917.

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Hersh CP, Washko GR, Estépar RS, Lutz S, Friedman PJ, Han MK, Hokanson JE, Judy PF, Lynch DA, Make BJ, Marchetti N, Newell JD Jr, Sciurba FC, Crapo JD, Silverman EK. Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD. Respir Res. 2013 Apr 8;14(1):42. doi: 10.1186/1465-9921-14-42. PubMed PMID: 23566024; PubMed Central PMCID: PMC3627637.

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Kumar N, Liang D, Comellas A, Chu AD, Abrams T. Satellite-based PM concentrations and their application to COPD in Cleveland, OH. J Expo Sci Environ Epidemiol. 2013 Nov-Dec;23(6):637-46. doi: 10.1038/jes.2013.52. Epub 2013 Sep 18. PubMed PMID: 24045428; PubMed Central PMCID: PMC3980441.

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Caraballo JC, Borcherding J, Rector M, Hornick E, Stoltz D, Zabner J, Comellas AP. Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model. PLoS One. 2014;9(1):e84434. doi: 10.1371/journal.pone.0084434. eCollection 2014. PubMed PMID: 24400090; PubMed Central PMCID: PMC3882223.

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Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH. Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir Med. 2014 Mar;2(3):214-25. doi: 10.1016/S2213-2600(14)70002-5. Epub 2014 Feb 7. PubMed PMID: 24621683; PubMed Central PMCID: PMC4176924.

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Borcherding J, Baltrusaitis J, Chen H, Stebounova L, Wu CM, Rubasinghege G, Mudunkotuwa IA, Caraballo JC, Zabner J, Grassian VH, Comellas AP. Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function. Environ Sci Nano. 2014 Apr;1(2):123-132. doi: 10.1039/C3EN00029J. PubMed PMID: 25221673; PubMed Central PMCID: PMC4158920.

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Kim V, Davey A, Comellas AP, Han MK, Washko G, Martinez CH, Lynch D, Lee JH, Silverman EK, Crapo JD, Make BJ, Criner GJ. Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study. Respir Res. 2014 Apr 27;15(1):52. doi: 10.1186/1465-9921-15-52. PubMed PMID: 24766722; PubMed Central PMCID: PMC4067738.

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Bhatt SP, Sieren JC, Newell JD Jr, Comellas AP, Hoffman EA. Disproportionate contribution of right middle lobe to emphysema and gas trapping on computed tomography. PLoS One. 2014;9(7):e102807. doi: 10.1371/journal.pone.0102807. eCollection 2014. PubMed PMID: 25054539; PubMed Central PMCID: PMC4108372.

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Wan ES, Castaldi PJ, Cho MH, Hokanson JE, Regan EA, Make BJ, Beaty TH, Han MK, Curtis JL, Curran-Everett D, Lynch DA, DeMeo DL, Crapo JD, Silverman EK. Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res. 2014 Aug 6;15(1):89. doi: 10.1186/s12931-014-0089-y. PubMed PMID: 25096860; PubMed Central PMCID: PMC4256936.

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Kim V, Desai P, Newell JD, Make BJ, Washko GR, Silverman EK, Crapo JD, Bhatt SP, Criner GJ. Airway wall thickness is increased in COPD patients with bronchodilator responsiveness. Respir Res. 2014 Aug 8;15(1):84. doi: 10.1186/s12931-014-0084-3. PubMed PMID: 25248436; PubMed Central PMCID: PMC4198908.

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Lee JH, Cho MH, McDonald ML, Hersh CP, Castaldi PJ, Crapo JD, Wan ES, Dy JG, Chang Y, Regan EA, Hardin M, DeMeo DL, Silverman EK. Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. Respir Med. 2014 Oct;108(10):1469-80. doi: 10.1016/j.rmed.2014.07.018. Epub 2014 Aug 11. PubMed PMID: 25154699; PubMed Central PMCID: PMC4253548.

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Lee JH, McDonald ML, Cho MH, Wan ES, Castaldi PJ, Hunninghake GM, Marchetti N, Lynch DA, Crapo JD, Lomas DA, Coxson HO, Bakke PS, Silverman EK, Hersh CP. DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. Respir Res. 2014 Aug 20;15(1):97. doi: 10.1186/s12931-014-0097-y. PubMed PMID: 25134640; PubMed Central PMCID: PMC4169636.

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Lee JH, Cho MH, Hersh CP, McDonald ML, Crapo JD, Bakke PS, Gulsvik A, Comellas AP, Wendt CH, Lomas DA, Kim V, Silverman EK. Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. Respir Res. 2014 Sep 21;15(1):113. doi: 10.1186/s12931-014-0113-2. PubMed PMID: 25241909; PubMed Central PMCID: PMC4190389.

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Bowler RP, Kim V, Regan E, Williams AAA, Santorico SA, Make BJ, Lynch DA, Hokanson JE, Washko GR, Bercz P, Soler X, Marchetti N, Criner GJ, Ramsdell J, Han MK, Demeo D, Anzueto A, Comellas A, Crapo JD, Dransfield M, Wells JM, Hersh CP, MacIntyre N, Martinez F, Nath HP, Niewoehner D, Sciurba F, Sharafkhaneh A, Silverman EK, van Beek EJR, Wilson C, Wendt C, Wise RA. Prediction of acute respiratory disease in current and former smokers with and without COPD. Chest. 2014 Oct;146(4):941-950. doi: 10.1378/chest.13-2946. PubMed PMID: 24945159; PubMed Central PMCID: PMC4188150.

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Carolan BJ, Hughes G, Morrow J, Hersh CP, O'Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne DA, Comellas AP, Han M, Zemans RL, Kechris K, Bowler RP. The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes. Respir Res. 2014 Oct 12;15(1):127. doi: 10.1186/s12931-014-0127-9. PubMed PMID: 25306249; PubMed Central PMCID: PMC4198701.

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Comellas AP, Pesce LM. Scorpion envenomation. N Engl J Med. 2014 Oct 16;371(16):1558. doi: 10.1056/NEJMc1410354. PubMed PMID: 25317886.

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Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, Ramsdell JW, Regan EA, Rennard SI, Schroeder JD, Sciurba FC, Steiner RM, Tal-Singer R, van Beek E Jr, Silverman EK, Crapo JD. Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. BMC Pulm Med. 2014 Oct 24;14:164. doi: 10.1186/1471-2466-14-164. PubMed PMID: 25341556; PubMed Central PMCID: PMC4216374.