Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Davidson AC, Bateman C, Shovlin C, Marrinan M, Burton GH, Cameron IR. Pulmonary toxicity of malaria prophylaxis. BMJ. 1988 Nov 12;297(6658):1240-1. doi: 10.1136/bmj.297.6658.1240. PubMed PMID: 3145065; PubMed Central PMCID: PMC1834720.
Shovlin CL, Tam FW. Salbutamol nebuliser and precipitation of critical cardiac ischaemia. Lancet. 1990 Nov 17;336(8725):1258. doi: 10.1016/0140-6736(90)92878-l. PubMed PMID: 1978102.
Rai GS, Shovlin C, Wesnes KA. A double-blind, placebo controlled study of Ginkgo biloba extract ('tanakan') in elderly outpatients with mild to moderate memory impairment. Curr Med Res Opin. 1991;12(6):350-5. doi: 10.1185/03007999109111504. PubMed PMID: 2044394.
Shovlin CL, Hughes JM, Simmonds HA, Fairbanks L, Deacock S, Lechler R, Roberts I, Webster AD. Adult presentation of adenosine deaminase deficiency. Lancet. 1993 Jun 5;341(8858):1471. doi: 10.1016/0140-6736(93)90910-9. PubMed PMID: 8099155.
Fairbanks LD, Shovlin CL, Webster AD, Hughes JM, Simmonds HA. Adenosine deaminase deficiency with altered biochemical parameters in two sisters with late-onset immunodeficiency. J Inherit Metab Dis. 1994;17(1):135-7. doi: 10.1007/bf00735418. PubMed PMID: 7914248.
Fairbanks LD, Simmonds HA, Webster AD, Shovlin CL, Hughes JM. Adenosine deaminase (ADA) deficiency as the unexpected cause of CD4+ T-lymphocytopenia in two HIV-negative adult female siblings. Adv Exp Med Biol. 1994;370:471-4. doi: 10.1007/978-1-4615-2584-4_100. PubMed PMID: 7660952.
Shovlin CL, Hughes JM, Tuddenham EG, Temperley I, Perembelon YF, Scott J, Seidman CE, Seidman JG. A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3. Nat Genet. 1994 Feb;6(2):205-9. doi: 10.1038/ng0294-205. PubMed PMID: 8162076.
Shovlin CL, Simmonds HA, Fairbanks LD, Deacock SJ, Hughes JM, Lechler RI, Webster AD, Sun XM, Webb JC, Soutar AK. Adult onset immunodeficiency caused by inherited adenosine deaminase deficiency. J Immunol. 1994 Sep 1;153(5):2331-9. PubMed PMID: 8051429.
Shovlin CL, Winstock AR, Peters AM, Jackson JE, Hughes JM. Medical complications of pregnancy in hereditary haemorrhagic telangiectasia. QJM. 1995 Dec;88(12):879-87. PubMed PMID: 8593547.
Shovlin CL, Scott J. Inherited diseases of the vasculature. Annu Rev Physiol. 1996;58:483-507. doi: 10.1146/ Review. PubMed PMID: 8815804.
Shovlin CL, Hughes JM. Hereditary hemorrhagic telangiectasia. N Engl J Med. 1996 Feb 1;334(5):330-1; author reply 331-2. PubMed PMID: 8532038.
Shovlin CL. Streamlined procedures for screening a P1 library. Biotechniques. 1996 Sep;21(3):388-90. doi: 10.2144/96213bm09. PubMed PMID: 8879570.
Encinas JA, Lees MB, Sobel RA, Symonowicz C, Greer JM, Shovlin CL, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. J Immunol. 1996 Sep 1;157(5):2186-92. PubMed PMID: 8757345.
Shovlin CL. Molecular defects in rare bleeding disorders: hereditary haemorrhagic telangiectasia. Thromb Haemost. 1997 Jul;78(1):145-50. Review. PubMed PMID: 9198145.
Shovlin CL, Hughes JM, Scott J, Seidman CE, Seidman JG. Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia. Am J Hum Genet. 1997 Jul;61(1):68-79. doi: 10.1086/513906. PubMed PMID: 9245986; PubMed Central PMCID: PMC1715873.
Shovlin CL. Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia. Clin Sci (Lond). 1998 Mar;94(3):207-18. doi: 10.1042/cs0940207. PubMed PMID: 9616253.
Shovlin CL, Letarte M. Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations: issues in clinical management and review of pathogenic mechanisms. Thorax. 1999 Aug;54(8):714-29. doi: 10.1136/thx.54.8.714. Review. PubMed PMID: 10413726; PubMed Central PMCID: PMC1745557.
Shovlin CL. Supermodels and disease: insights from the HHT mice. J Clin Invest. 1999 Nov;104(10):1335-6. doi: 10.1172/JCI8730. Review. PubMed PMID: 10562293; PubMed Central PMCID: PMC409851.
Shovlin CL, Guttmacher AE, Buscarini E, Faughnan ME, Hyland RH, Westermann CJ, Kjeldsen AD, Plauchu H. Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome). Am J Med Genet. 2000 Mar 6;91(1):66-7. doi: 10.1002/(sici)1096-8628(20000306)91:1<66::aid-ajmg12>;2-p. PubMed PMID: 10751092.
Wallace GM, Shovlin CL. A hereditary haemorrhagic telangiectasia family with pulmonary involvement is unlinked to the known HHT genes, endoglin and ALK-1. Thorax. 2000 Aug;55(8):685-90. doi: 10.1136/thorax.55.8.685. PubMed PMID: 10899246; PubMed Central PMCID: PMC1745830.
Wilkins MR, Gibbs JS, Shovlin CL. A gene for primary pulmonary hypertension. Lancet. 2000 Oct 7;356(9237):1207-8. doi: 10.1016/s0140-6736(00)02777-x. PubMed PMID: 11072932.
Shovlin CL. Genetic aspects of cerebrovascular malformations. Interv Neuroradiol. 2000 Jun 30;6(2):107-11. doi: 10.1177/159101990000600204. Epub 2001 May 15. PubMed PMID: 20667188; PubMed Central PMCID: PMC3679585.
Paquet ME, Pece-Barbara N, Vera S, Cymerman U, Karabegovic A, Shovlin C, Letarte M. Analysis of several endoglin mutants reveals no endogenous mature or secreted protein capable of interfering with normal endoglin function. Hum Mol Genet. 2001 Jun 15;10(13):1347-57. doi: 10.1093/hmg/10.13.1347. PubMed PMID: 11440987.
Whittle AT, Davis M, Shovlin CL, Ganly PS, Haslett C, Greening AP. Alveolar macrophage activity and the pulmonary complications of haematopoietic stem cell transplantation. Thorax. 2001 Dec;56(12):941-6. doi: 10.1136/thorax.56.12.941. PubMed PMID: 11713357; PubMed Central PMCID: PMC1745976.
Gupta P, Mordin C, Curtis J, Hughes JM, Shovlin CL, Jackson JE. Pulmonary arteriovenous malformations: effect of embolization on right-to-left shunt, hypoxemia, and exercise tolerance in 66 patients. AJR Am J Roentgenol. 2002 Aug;179(2):347-55. doi: 10.2214/ajr.179.2.1790347. PubMed PMID: 12130431.
Begbie ME, Wallace GM, Shovlin CL. Hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): a view from the 21st century. Postgrad Med J. 2003 Jan;79(927):18-24. doi: 10.1136/pmj.79.927.18. Review. PubMed PMID: 12566546; PubMed Central PMCID: PMC1742589.
Easey AJ, Wallace GM, Hughes JM, Jackson JE, Taylor WJ, Shovlin CL. Should asymptomatic patients with hereditary haemorrhagic telangiectasia (HHT) be screened for cerebral vascular malformations? Data from 22,061 years of HHT patient life. J Neurol Neurosurg Psychiatry. 2003 Jun;74(6):743-8. doi: 10.1136/jnnp.74.6.743. PubMed PMID: 12754343; PubMed Central PMCID: PMC1738468.
Wheatley-Price P, Shovlin C, Chao D. Interferon for metastatic renal cell cancer causing regression of hereditary hemorrhagic telangiectasia. J Clin Gastroenterol. 2005 Apr;39(4):344-5. doi: 10.1097/01.mcg.0000155137.73433.36. PubMed PMID: 15758631.
Cole SG, Begbie ME, Wallace GM, Shovlin CL. A new locus for hereditary haemorrhagic telangiectasia (HHT3) maps to chromosome 5. J Med Genet. 2005 Jul;42(7):577-82. doi: 10.1136/jmg.2004.028712. PubMed PMID: 15994879; PubMed Central PMCID: PMC1736109.
Saleh JA, Alasia DD. Acute pulmonary embolism: a review. Niger J Med. 2007 Jan-Mar;16(1):11-7. doi: 10.4314/njm.v16i1.37274. Review. PubMed PMID: 17563962.
Shovlin CL, Sulaiman NL, Govani FS, Jackson JE, Begbie ME. Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. Thromb Haemost. 2007 Nov;98(5):1031-9. PubMed PMID: 18000608.
Shovlin CL, Jackson JE, Bamford KB, Jenkins IH, Benjamin AR, Ramadan H, Kulinskaya E. Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia. Thorax. 2008 Mar;63(3):259-66. doi: 10.1136/thx.2007.087452. Epub 2007 Nov 2. PubMed PMID: 17981912.
Shovlin CL, Tighe HC, Davies RJ, Gibbs JS, Jackson JE. Embolisation of pulmonary arteriovenous malformations: no consistent effect on pulmonary artery pressure. Eur Respir J. 2008 Jul;32(1):162-9. doi: 10.1183/09031936.00126207. Epub 2008 Apr 2. PubMed PMID: 18385173.
Shovlin CL, Sodhi V, McCarthy A, Lasjaunias P, Jackson JE, Sheppard MN. Estimates of maternal risks of pregnancy for women with hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): suggested approach for obstetric services. BJOG. 2008 Aug;115(9):1108-15. doi: 10.1111/j.1471-0528.2008.01786.x. Epub 2008 May 30. PubMed PMID: 18518871.
Shovlin C, Bamford K, Wray D. Post-NICE 2008: Antibiotic prophylaxis prior to dental procedures for patients with pulmonary arteriovenous malformations (PAVMs) and hereditary haemorrhagic telangiectasia. Br Dent J. 2008 Nov 22;205(10):531-3. doi: 10.1038/sj.bdj.2008.978. PubMed PMID: 19023305.
Shovlin CL, Gibbs JS, Jackson JE. Management of pulmonary arteriovenous malformations in pulmonary hypertensive patients: a pressure to embolise?. Eur Respir Rev. 2009 Mar;18(111):4-6. doi: 10.1183/09059180.00011102. PubMed PMID: 20956115.
Govani FS, Shovlin CL. Hereditary haemorrhagic telangiectasia: a clinical and scientific review. Eur J Hum Genet. 2009 Jul;17(7):860-71. doi: 10.1038/ejhg.2009.35. Epub 2009 Apr 1. Review. PubMed PMID: 19337313; PubMed Central PMCID: PMC2986493.
Shovlin CL, Angus G, Manning RA, Okoli GN, Govani FS, Elderfield K, Birdsey GM, Mollet IG, Laffan MA, Mauri FA. Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. PLoS One. 2010 Feb 11;5(2):e9154. doi: 10.1371/journal.pone.0009154. PubMed PMID: 20174619; PubMed Central PMCID: PMC2823490.
Key NS, DE Paepe A, Malfait F, Shovlin CL. Vascular haemostasis. Haemophilia. 2010 Jul;16 Suppl 5:146-51. doi: 10.1111/j.1365-2516.2010.02313.x. PubMed PMID: 20590874.
Govani FS, Shovlin CL. Fine mapping of the hereditary haemorrhagic telangiectasia (HHT)3 locus on chromosome 5 excludes VE-Cadherin-2, Sprouty4 and other interval genes. J Angiogenes Res. 2010 Aug 11;2:15. doi: 10.1186/2040-2384-2-15. PubMed PMID: 20701797; PubMed Central PMCID: PMC2924844.
Shovlin CL. Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment. Blood Rev. 2010 Nov;24(6):203-19. doi: 10.1016/j.blre.2010.07.001. Epub 2010 Sep 25. Review. PubMed PMID: 20870325.
Hart JL, Aldin Z, Braude P, Shovlin CL, Jackson J. Embolization of pulmonary arteriovenous malformations using the Amplatzer vascular plug: successful treatment of 69 consecutive patients. Eur Radiol. 2010 Nov;20(11):2663-70. doi: 10.1007/s00330-010-1851-2. Epub 2010 Jun 24. PubMed PMID: 20574633.
Roked F, Jackson JE, Fuld J, Basheer FT, Chilvers ER, Beattie S, Shovlin CL. Pulmonary thromboemboli modifying the natural history of pulmonary arteriovenous malformations. Am J Respir Crit Care Med. 2011 Mar 15;183(6):828-9. doi: 10.1164/ajrccm.183.6.828. PubMed PMID: 21471070.
Ahmedzai S, Balfour-Lynn IM, Bewick T, Buchdahl R, Coker RK, Cummin AR, Gradwell DP, Howard L, Innes JA, Johnson AO, Lim E, Lim WS, McKinlay KP, Partridge MR, Popplestone M, Pozniak A, Robson A, Shovlin CL, Shrikrishna D, Simonds A, Tait P, Thomas M. Managing passengers with stable respiratory disease planning air travel: British Thoracic Society recommendations. Thorax. 2011 Sep;66 Suppl 1:i1-30. doi: 10.1136/thoraxjnl-2011-200295. PubMed PMID: 21856702.
Mason CG, Shovlin CL. Flight-related complications are infrequent in patients with hereditary haemorrhagic telangiectasia/pulmonary arteriovenous malformations, despite low oxygen saturations and anaemia. Thorax. 2012 Jan;67(1):80-1. doi: 10.1136/thoraxjnl-2011-201027. Epub 2011 Sep 26. PubMed PMID: 21953065.
Livesey JA, Manning RA, Meek JH, Jackson JE, Kulinskaya E, Laffan MA, Shovlin CL. Low serum iron levels are associated with elevated plasma levels of coagulation factor VIII and pulmonary emboli/deep venous thromboses in replicate cohorts of patients with hereditary haemorrhagic telangiectasia. Thorax. 2012 Apr;67(4):328-33. doi: 10.1136/thoraxjnl-2011-201076. Epub 2011 Dec 14. PubMed PMID: 22169361.
Verkerk MM, Shovlin CL, Lund VJ. Silent threat? A retrospective study of screening practices for pulmonary arteriovenous malformations in patients with hereditary haemorrhagic telangiectasia. Rhinology. 2012 Sep;50(3):277-83. doi: 10.4193/Rhino12.043. PubMed PMID: 22888484.
Devlin HL, Hosman AE, Shovlin CL. Antiplatelet and anticoagulant agents in hereditary hemorrhagic telangiectasia. N Engl J Med. 2013 Feb 28;368(9):876-8. doi: 10.1056/NEJMc1213554. PubMed PMID: 23445111.
Govani FS, Giess A, Mollet IG, Begbie ME, Jones MD, Game L, Shovlin CL. Directional next-generation RNA sequencing and examination of premature termination codon mutations in endoglin/hereditary haemorrhagic telangiectasia. Mol Syndromol. 2013 Apr;4(4):184-96. doi: 10.1159/000350208. Epub 2013 Apr 11. PubMed PMID: 23801935; PubMed Central PMCID: PMC3666459.
Silva BM, Hosman AE, Devlin HL, Shovlin CL. Lifestyle and dietary influences on nosebleed severity in hereditary hemorrhagic telangiectasia. Laryngoscope. 2013 May;123(5):1092-9. doi: 10.1002/lary.23893. Epub 2013 Feb 12. PubMed PMID: 23404156.
What would you like to do?