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Duan D, Kim LJ, Jun JC, Polotsky VY. Connecting insufficient sleep and insomnia with metabolic dysfunction. Ann N Y Acad Sci. 2023 Jan;1519(1):94-117. doi: 10.1111/nyas.14926. Epub 2022 Nov 13. Review. PubMed PMID: 36373239; PubMed Central PMCID: PMC9839511.
Duan D, Gu C, Polotsky VY, Jun JC, Pham LV. Effects of Dinner Timing on Sleep Stage Distribution and EEG Power Spectrum in Healthy Volunteers. Nat Sci Sleep. 2021;13:601-612. doi: 10.2147/NSS.S301113. eCollection 2021. PubMed PMID: 34017207; PubMed Central PMCID: PMC8131073.
Gu C, Brereton N, Schweitzer A, Cotter M, Duan D, Børsheim E, Wolfe RR, Pham LV, Polotsky VY, Jun JC. Metabolic Effects of Late Dinner in Healthy Volunteers-A Randomized Crossover Clinical Trial. J Clin Endocrinol Metab. 2020 Aug 1;105(8). doi: 10.1210/clinem/dgaa354. PubMed PMID: 32525525; PubMed Central PMCID: PMC7337187.
Duan D, Gu C, Jun JC. Altered metabolism in pulmonary hypertension: fuelling the fire or just smoke?. Eur Respir J. 2020 Apr;55(4). doi: 10.1183/13993003.00447-2020. Print 2020 Apr. PubMed PMID: 32273332; PubMed Central PMCID: PMC7573924.
Jun JC, Polotsky VY. Obstructive sleep apnoea and susceptibility to cardiovascular disease: A blessing or curse of old age?. Respirology. 2020 Mar;25(3):242-243. doi: 10.1111/resp.13679. Epub 2019 Aug 14. PubMed PMID: 31411783; PubMed Central PMCID: PMC7561252.
Kim DE, Hefter G, Jun JC. Atypical Electrocardiographic Changes on Polysomnogram. Ann Am Thorac Soc. 2019 Sep;16(9):1192-1194. doi: 10.1513/AnnalsATS.201812-895CC. PubMed PMID: 31469314.
Jun JC, Swenson ER. Commentary: Intermittent Hypoxia Severity in Animal Models of Sleep Apnea. Front Physiol. 2019;10:609. doi: 10.3389/fphys.2019.00609. eCollection 2019. PubMed PMID: 31231229; PubMed Central PMCID: PMC6558364.
Berger S, Pho H, Fleury-Curado T, Bevans-Fonti S, Younas H, Shin MK, Jun JC, Anokye-Danso F, Ahima RS, Enquist LW, Mendelowitz D, Schwartz AR, Polotsky VY. Intranasal Leptin Relieves Sleep-disordered Breathing in Mice with Diet-induced Obesity. Am J Respir Crit Care Med. 2019 Mar 15;199(6):773-783. doi: 10.1164/rccm.201805-0879OC. PubMed PMID: 30309268; PubMed Central PMCID: PMC6423095.
Younas H, Roda R, Jun J. Obstructive sleep apnoea and hypoventilation in an adult with congenital myasthenic syndrome. BMJ Case Rep. 2018 Nov 14;2018. doi: 10.1136/bcr-2018-226534. PubMed PMID: 30429133; PubMed Central PMCID: PMC6254377.
Gu C, Jun JC. Does Hypoxia Decrease the Metabolic Rate?. Front Endocrinol (Lausanne). 2018;9:668. doi: 10.3389/fendo.2018.00668. eCollection 2018. Review. PubMed PMID: 30555410; PubMed Central PMCID: PMC6282065.
Gu C, Jun JC. Continuous Positive Airway Pressure Titration: A Minor Change Can Make a Major Difference. Ann Am Thorac Soc. 2018 Sep;15(9):1105-1107. doi: 10.1513/AnnalsATS.201801-064CC. PubMed PMID: 30168748.
Pham LV, Schwartz AR, Jun JC. Oxyhemoglobin Saturation Overshoot Following Obstructive Breathing Events Mitigates Sleep Apnea-Induced Glucose Elevations. Front Endocrinol (Lausanne). 2018;9:477. doi: 10.3389/fendo.2018.00477. eCollection 2018. PubMed PMID: 30190705; PubMed Central PMCID: PMC6115486.
Gu C, Younas H, Jun JC. Sleep apnea: An overlooked cause of lipotoxicity?. Med Hypotheses. 2017 Oct;108:161-165. doi: 10.1016/j.mehy.2017.09.007. Epub 2017 Sep 13. PubMed PMID: 29055392; PubMed Central PMCID: PMC5685168.
Chopra S, Rathore A, Younas H, Pham LV, Gu C, Beselman A, Kim IY, Wolfe RR, Perin J, Polotsky VY, Jun JC. Obstructive Sleep Apnea Dynamically Increases Nocturnal Plasma Free Fatty Acids, Glucose, and Cortisol During Sleep. J Clin Endocrinol Metab. 2017 Sep 1;102(9):3172-3181. doi: 10.1210/jc.2017-00619. PubMed PMID: 28595341; PubMed Central PMCID: PMC5587067.
Jun JC, Rathore A, Younas H, Gilkes D, Polotsky VY. Hypoxia-Inducible Factors and Cancer. Curr Sleep Med Rep. 2017 Mar;3(1):1-10. doi: 10.1007/s40675-017-0062-7. Epub 2017 Jan 28. PubMed PMID: 28944164; PubMed Central PMCID: PMC5607450.
Jun JC, Devera R, Unnikrishnan D, Shin MK, Bevans-Fonti S, Yao Q, Rathore A, Younas H, Halberg N, Scherer PE, Polotsky VY. Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis. J Mol Med (Berl). 2017 Mar;95(3):287-297. doi: 10.1007/s00109-016-1480-6. Epub 2016 Oct 14. PubMed PMID: 27738746; PubMed Central PMCID: PMC5322176.
Owens RL, Gold KA, Gozal D, Peppard PE, Jun JC, Dannenberg AJ, Lippman SM, Malhotra A. Sleep and Breathing … and Cancer?. Cancer Prev Res (Phila). 2016 Nov;9(11):821-827. doi: 10.1158/1940-6207.CAPR-16-0092. Epub 2016 Sep 7. Review. PubMed PMID: 27604751; PubMed Central PMCID: PMC5353979.
Miele CH, Schwartz AR, Gilman RH, Pham L, Wise RA, Davila-Roman VG, Jun JC, Polotsky VY, Miranda JJ, Leon-Velarde F, Checkley W. Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude. High Alt Med Biol. 2016 Jun;17(2):93-100. doi: 10.1089/ham.2015.0084. PubMed PMID: 27281472; PubMed Central PMCID: PMC4913510.
Jun JC, Chopra S, Schwartz AR. Sleep apnoea. Eur Respir Rev. 2016 Mar;25(139):12-8. doi: 10.1183/16000617.0077-2015. Review. PubMed PMID: 26929416; PubMed Central PMCID: PMC5686780.
Chopra S, Polotsky VY, Jun JC. Sleep Apnea Research in Animals. Past, Present, and Future. Am J Respir Cell Mol Biol. 2016 Mar;54(3):299-305. doi: 10.1165/rcmb.2015-0218TR. Review. PubMed PMID: 26448201; PubMed Central PMCID: PMC4821036.
Jun JC, Polotsky VY. Stressful sleep. Eur Respir J. 2016 Feb;47(2):366-8. doi: 10.1183/13993003.01920-2015. PubMed PMID: 26828044; PubMed Central PMCID: PMC5686781.
Jun JC, Unnikrishnan D, Schneider H, Kirkness J, Schwartz AR, Smith PL, Polotsky VY. Effect of Acute Intermittent CPAP Depressurization during Sleep in Obese Patients. PLoS One. 2016;11(1):e0146606. doi: 10.1371/journal.pone.0146606. eCollection 2016. PubMed PMID: 26731735; PubMed Central PMCID: PMC4701426.
Mesarwi OA, Shin MK, Drager LF, Bevans-Fonti S, Jun JC, Putcha N, Torbenson MS, Pedrosa RP, Lorenzi-Filho G, Steele KE, Schweitzer MA, Magnuson TH, Lidor AO, Schwartz AR, Polotsky VY. Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea. Sleep. 2015 Oct 1;38(10):1583-91. doi: 10.5665/sleep.5052. PubMed PMID: 26085300; PubMed Central PMCID: PMC4576332.
Jun JC, Polotsky VY. Are we waking up to the effects of NEFA?. Diabetologia. 2015 Apr;58(4):651-3. doi: 10.1007/s00125-014-3489-0. Epub 2015 Jan 25. PubMed PMID: 25617999; PubMed Central PMCID: PMC4352391.
Unnikrishnan D, Jun J, Polotsky V. Inflammation in sleep apnea: an update. Rev Endocr Metab Disord. 2015 Mar;16(1):25-34. doi: 10.1007/s11154-014-9304-x. Review. PubMed PMID: 25502450; PubMed Central PMCID: PMC4346503.
Mesarwi OA, Sharma EV, Jun JC, Polotsky VY. Metabolic dysfunction in obstructive sleep apnea: A critical examination of underlying mechanisms. Sleep Biol Rhythms. 2015 Jan;13(1):2-17. doi: 10.1111/sbr.12078. PubMed PMID: 26412981; PubMed Central PMCID: PMC4583137.
Jun JC, Shin MK, Devera R, Yao Q, Mesarwi O, Bevans-Fonti S, Polotsky VY. Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy. Am J Physiol Endocrinol Metab. 2014 Dec 1;307(11):E1073-83. doi: 10.1152/ajpendo.00373.2014. Epub 2014 Oct 14. PubMed PMID: 25315697; PubMed Central PMCID: PMC4254988.
Shin MK, Han W, Bevans-Fonti S, Jun JC, Punjabi NM, Polotsky VY. The effect of adrenal medullectomy on metabolic responses to chronic intermittent hypoxia. Respir Physiol Neurobiol. 2014 Nov 1;203:60-7. doi: 10.1016/j.resp.2014.08.018. Epub 2014 Aug 29. PubMed PMID: 25179887; PubMed Central PMCID: PMC4179502.
Shin MK, Yao Q, Jun JC, Bevans-Fonti S, Yoo DY, Han W, Mesarwi O, Richardson R, Fu YY, Pasricha PJ, Schwartz AR, Shirahata M, Polotsky VY. Carotid body denervation prevents fasting hyperglycemia during chronic intermittent hypoxia. J Appl Physiol (1985). 2014 Oct 1;117(7):765-76. doi: 10.1152/japplphysiol.01133.2013. Epub 2014 Aug 7. PubMed PMID: 25103977; PubMed Central PMCID: PMC4187050.
Mesarwi O, Polak J, Jun J, Polotsky VY. Sleep disorders and the development of insulin resistance and obesity. Endocrinol Metab Clin North Am. 2013 Sep;42(3):617-34. doi: 10.1016/j.ecl.2013.05.001. Review. PubMed PMID: 24011890; PubMed Central PMCID: PMC3767932.
Drager LF, Yao Q, Hernandez KL, Shin MK, Bevans-Fonti S, Gay J, Sussan TE, Jun JC, Myers AC, Olivecrona G, Schwartz AR, Halberg N, Scherer PE, Semenza GL, Powell DR, Polotsky VY. Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. Am J Respir Crit Care Med. 2013 Jul 15;188(2):240-8. doi: 10.1164/rccm.201209-1688OC. PubMed PMID: 23328524; PubMed Central PMCID: PMC3778753.
Yao Q, Shin MK, Jun JC, Hernandez KL, Aggarwal NR, Mock JR, Gay J, Drager LF, Polotsky VY. Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues. J Lipid Res. 2013 Apr;54(4):1058-65. doi: 10.1194/jlr.M034272. Epub 2013 Feb 5. PubMed PMID: 23386706; PubMed Central PMCID: PMC3605982.
Bose S, Jun J, Diette GB. High-frequency chest wall oscillation successful in controlling refractory asthma. J Asthma. 2013 Mar;50(2):219-21. doi: 10.3109/02770903.2012.757773. PubMed PMID: 23394251; PubMed Central PMCID: PMC4888798.
Jun JC, Shin MK, Yao Q, Devera R, Fonti-Bevans S, Polotsky VY. Thermoneutrality modifies the impact of hypoxia on lipid metabolism. Am J Physiol Endocrinol Metab. 2013 Feb 15;304(4):E424-35. doi: 10.1152/ajpendo.00515.2012. Epub 2012 Dec 18. PubMed PMID: 23249698; PubMed Central PMCID: PMC3566502.
Jun JC, Polotsky VY. Sleep and sleep loss: an energy paradox?. Sleep. 2012 Nov 1;35(11):1447-8. doi: 10.5665/sleep.2184. PubMed PMID: 23115392; PubMed Central PMCID: PMC3466790.
Shin MK, Drager LF, Yao Q, Bevans-Fonti S, Yoo DY, Jun JC, Aja S, Bhanot S, Polotsky VY. Metabolic consequences of high-fat diet are attenuated by suppression of HIF-1α. PLoS One. 2012;7(10):e46562. doi: 10.1371/journal.pone.0046562. Epub 2012 Oct 1. PubMed PMID: 23049707; PubMed Central PMCID: PMC3462192.
Jun JC, Shin MK, Yao Q, Bevans-Fonti S, Poole J, Drager LF, Polotsky VY. Acute hypoxia induces hypertriglyceridemia by decreasing plasma triglyceride clearance in mice. Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E377-88. doi: 10.1152/ajpendo.00641.2011. Epub 2012 May 22. PubMed PMID: 22621867; PubMed Central PMCID: PMC3423119.
Drager LF, Li J, Shin MK, Reinke C, Aggarwal NR, Jun JC, Bevans-Fonti S, Sztalryd C, O'Byrne SM, Kroupa O, Olivecrona G, Blaner WS, Polotsky VY. Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea. Eur Heart J. 2012 Mar;33(6):783-90. doi: 10.1093/eurheartj/ehr097. Epub 2011 Apr 9. PubMed PMID: 21478490; PubMed Central PMCID: PMC3303712.
Drager LF, Li J, Reinke C, Bevans-Fonti S, Jun JC, Polotsky VY. Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. Obesity (Silver Spring). 2011 Nov;19(11):2167-74. doi: 10.1038/oby.2011.240. Epub 2011 Jul 28. PubMed PMID: 21799478; PubMed Central PMCID: PMC4461029.
Jun JC, Drager LF, Najjar SS, Gottlieb SS, Brown CD, Smith PL, Schwartz AR, Polotsky VY. Effects of sleep apnea on nocturnal free fatty acids in subjects with heart failure. Sleep. 2011 Sep 1;34(9):1207-13. doi: 10.5665/SLEEP.1240. PubMed PMID: 21886358; PubMed Central PMCID: PMC3157662.
Drager LF, Jun JC, Polotsky VY. Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. Best Pract Res Clin Endocrinol Metab. 2010 Oct;24(5):843-51. doi: 10.1016/j.beem.2010.08.011. Review. PubMed PMID: 21112030; PubMed Central PMCID: PMC3011976.
Drager LF, Lopes HF, Maki-Nunes C, Trombetta IC, Toschi-Dias E, Alves MJ, Fraga RF, Jun JC, Negrão CE, Krieger EM, Polotsky VY, Lorenzi-Filho G. The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome. PLoS One. 2010 Aug 11;5(8):e12065. doi: 10.1371/journal.pone.0012065. PubMed PMID: 20711453; PubMed Central PMCID: PMC2920316.
Jun J, Reinke C, Bedja D, Berkowitz D, Bevans-Fonti S, Li J, Barouch LA, Gabrielson K, Polotsky VY. Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 2010 Apr;209(2):381-6. doi: 10.1016/j.atherosclerosis.2009.10.017. Epub 2009 Oct 17. PubMed PMID: 19897196; PubMed Central PMCID: PMC2846209.
Drager LF, Jun J, Polotsky VY. Obstructive sleep apnea and dyslipidemia: implications for atherosclerosis. Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):161-5. doi: 10.1097/MED.0b013e3283373624. Review. PubMed PMID: 20125003; PubMed Central PMCID: PMC2904751.
Savransky V, Reinke C, Jun J, Bevans-Fonti S, Nanayakkara A, Li J, Myers AC, Torbenson MS, Polotsky VY. Chronic intermittent hypoxia and acetaminophen induce synergistic liver injury in mice. Exp Physiol. 2009 Feb;94(2):228-39. doi: 10.1113/expphysiol.2008.044883. Epub 2008 Nov 21. PubMed PMID: 19028810; PubMed Central PMCID: PMC2852632.
Jun J, Polotsky VY. Metabolic consequences of sleep-disordered breathing. ILAR J. 2009;50(3):289-306. doi: 10.1093/ilar.50.3.289. Review. PubMed PMID: 19506316; PubMed Central PMCID: PMC5689472.
Sussan TE, Jun J, Thimmulappa R, Bedja D, Antero M, Gabrielson KL, Polotsky VY, Biswal S. Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. PLoS One. 2008;3(11):e3791. doi: 10.1371/journal.pone.0003791. Epub 2008 Nov 21. PubMed PMID: 19023427; PubMed Central PMCID: PMC2582492.
Savransky V, Jun J, Li J, Nanayakkara A, Fonti S, Moser AB, Steele KE, Schweitzer MA, Patil SP, Bhanot S, Schwartz AR, Polotsky VY. Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase. Circ Res. 2008 Nov 7;103(10):1173-80. doi: 10.1161/CIRCRESAHA.108.178533. Epub 2008 Oct 2. PubMed PMID: 18832746; PubMed Central PMCID: PMC2658638.
Jun J, Savransky V, Nanayakkara A, Bevans S, Li J, Smith PL, Polotsky VY. Intermittent hypoxia has organ-specific effects on oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1274-81. doi: 10.1152/ajpregu.90346.2008. Epub 2008 Aug 13. PubMed PMID: 18703411; PubMed Central PMCID: PMC2576102.
Li J, Nanayakkara A, Jun J, Savransky V, Polotsky VY. Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia. Physiol Genomics. 2007 Oct 22;31(2):273-80. doi: 10.1152/physiolgenomics.00082.2007. Epub 2007 Jul 31. PubMed PMID: 17666524.
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