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Zubčić K, Radovanović V, Vlainić J, Hof PR, Oršolić N, Šimić G, Jazvinšćak Jembrek M. PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury. Oxid Med Cell Longev. 2020;2020:9834742. doi: 10.1155/2020/9834742. eCollection 2020. PubMed PMID: 32733640; PubMed Central PMCID: PMC7369662.
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D, Brunmeir R, Yeap YJ, O'Brien NL, Groet J, Shao X, Havlicek S, Dunn NR, Kvartsberg H, Brinkmalm G, Hithersay R, Startin C, Hamburg S, Phillips M, Pervushin K, Turmaine M, Wallon D, Rovelet-Lecrux A, Soininen H, Volpi E, Martin JE, Foo JN, Becker DL, Rostagno A, Ghiso J, Krsnik Ž, Šimić G, Kostović I, Mitrečić D, Francis PT, Blennow K, Strydom A, Hardy J, Zetterberg H, Nižetić D. Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain. Mol Psychiatry. 2020 Jul 10;. doi: 10.1038/s41380-020-0806-5. [Epub ahead of print] PubMed PMID: 32647257.
Bažadona D, Fabek I, Babić Leko M, Bobić Rasonja M, Kalinić D, Bilić E, Raguž JD, Mimica N, Borovečki F, Hof PR, Šimić G. A non-invasive hidden-goal test for spatial orientation deficit detection in subjects with suspected mild cognitive impairment. J Neurosci Methods. 2020 Feb 15;332:108547. doi: 10.1016/j.jneumeth.2019.108547. Epub 2019 Dec 9. Review. PubMed PMID: 31830545; PubMed Central PMCID: PMC6990141.
Babić Leko M, Nikolac Perković M, Klepac N, Švob Štrac D, Borovečki F, Pivac N, Hof PR, Šimić G. Relationships of Cerebrospinal Fluid Alzheimer's Disease Biomarkers and COMT, DBH, and MAOB Single Nucleotide Polymorphisms. J Alzheimers Dis. 2020;73(1):135-145. doi: 10.3233/JAD-190991. PubMed PMID: 31771069; PubMed Central PMCID: PMC7029364.
Babić Leko M, Nikolac Perković M, Klepac N, Štrac DŠ, Borovečki F, Pivac N, Hof PR, Šimić G. IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer's Disease Pathology. J Alzheimers Dis. 2020;75(3):1029-1047. doi: 10.3233/JAD-200056. PubMed PMID: 32390629.
Šimić G. Rare diseases and omics-driven personalized medicine. Croat Med J. 2019 Dec 31;60(6):485-487. PubMed PMID: 31894912; PubMed Central PMCID: PMC6952900.
Španić E, Langer Horvat L, Hof PR, Šimić G. Role of Microglial Cells in Alzheimer's Disease Tau Propagation. Front Aging Neurosci. 2019;11:271. doi: 10.3389/fnagi.2019.00271. eCollection 2019. PubMed PMID: 31636558; PubMed Central PMCID: PMC6787141.
Šimić G, Španić E, Langer Horvat L, Hof PR. Blood-brain barrier and innate immunity in the pathogenesis of Alzheimer's disease. Prog Mol Biol Transl Sci. 2019;168:99-145. doi: 10.1016/bs.pmbts.2019.06.003. Epub 2019 Jul 3. Review. PubMed PMID: 31699331.
Boban M, Babić Leko M, Miškić T, Hof PR, Šimić G. Human neuroblastoma SH-SY5Y cells treated with okadaic acid express phosphorylated high molecular weight tau-immunoreactive protein species. J Neurosci Methods. 2019 May 1;319:60-68. doi: 10.1016/j.jneumeth.2018.09.030. Epub 2018 Sep 29. PubMed PMID: 30278184; PubMed Central PMCID: PMC6440880.
Ilic K, Mlinac-Jerkovic K, Jovanov-Milosevic N, Simic G, Habek N, Bogdanovic N, Kalanj-Bognar S. Hippocampal expression of cell-adhesion glycoprotein neuroplastin is altered in Alzheimer's disease. J Cell Mol Med. 2019 Feb;23(2):1602-1607. doi: 10.1111/jcmm.13998. Epub 2018 Nov 28. PubMed PMID: 30488668; PubMed Central PMCID: PMC6349345.
Babić Leko M, Župunski V, Kirincich J, Smilović D, Hortobágyi T, Hof PR, Šimić G. Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion. Behav Neurol. 2019;2019:2909168. doi: 10.1155/2019/2909168. eCollection 2019. Review. PubMed PMID: 30774737; PubMed Central PMCID: PMC6350563.
Babić Leko M, Willumsen N, Nikolac Perković M, Klepac N, Borovečki F, Hof PR, Sonicki Z, Pivac N, de Silva R, Šimić G. Association of MAPT haplotype-tagging polymorphisms with cerebrospinal fluid biomarkers of Alzheimer's disease: A preliminary study in a Croatian cohort. Brain Behav. 2018 Nov;8(11):e01128. doi: 10.1002/brb3.1128. Epub 2018 Oct 17. PubMed PMID: 30329219; PubMed Central PMCID: PMC6236251.
Jazvinšćak Jembrek M, Slade N, Hof PR, Šimić G. The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer's disease. Prog Neurobiol. 2018 Sep;168:104-127. doi: 10.1016/j.pneurobio.2018.05.001. Epub 2018 May 4. Review. PubMed PMID: 29733887.
Kiđemet-Piskač S, Babić Leko M, Blažeković A, Langer Horvat L, Klepac N, Sonicki Z, Kolenc D, Hof PR, Boban M, Mimica N, Borovečki F, Šimić G. Evaluation of cerebrospinal fluid phosphorylated tau231 as a biomarker in the differential diagnosis of Alzheimer's disease and vascular dementia. CNS Neurosci Ther. 2018 Aug;24(8):734-740. doi: 10.1111/cns.12814. Epub 2018 Feb 17. PubMed PMID: 29453935; PubMed Central PMCID: PMC6047904.
Babić Leko M, Krbot Skorić M, Klepac N, Borovečki F, Langer Horvat L, Vogrinc Ž, Sonicki Z, Hof PR, Šimić G. Event-related Potentials Improve the Efficiency of Cerebrospinal Fluid Biomarkers for Differential Diagnosis of Alzheimer's Disease. Curr Alzheimer Res. 2018;15(13):1244-1260. doi: 10.2174/1567205015666180911151116. PubMed PMID: 30207231.
Mihelčić M, Šimić G, Babić Leko M, Lavrač N, Džeroski S, Šmuc T. Using redescription mining to relate clinical and biological characteristics of cognitively impaired and Alzheimer's disease patients. PLoS One. 2017;12(10):e0187364. doi: 10.1371/journal.pone.0187364. eCollection 2017. PubMed PMID: 29088293; PubMed Central PMCID: PMC5663625.
Charvet CJ, Šimić G, Kostović I, Knezović V, Vukšić M, Babić Leko M, Takahashi E, Sherwood CC, Wolfe MD, Finlay BL. Coevolution in the timing of GABAergic and pyramidal neuron maturation in primates. Proc Biol Sci. 2017 Aug 30;284(1861). doi: 10.1098/rspb.2017.1169. PubMed PMID: 28855363; PubMed Central PMCID: PMC5577486.
Herrera-Molina R, Mlinac-Jerkovic K, Ilic K, Stöber F, Vemula SK, Sandoval M, Milosevic NJ, Simic G, Smalla KH, Goldschmidt J, Bognar SK, Montag D. Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration. Sci Rep. 2017 Aug 4;7(1):7273. doi: 10.1038/s41598-017-07839-9. PubMed PMID: 28779130; PubMed Central PMCID: PMC5544750.
Šimić G, Babić Leko M, Wray S, Harrington CR, Delalle I, Jovanov-Milošević N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik CM, Hof PR. Monoaminergic neuropathology in Alzheimer's disease. Prog Neurobiol. 2017 Apr;151:101-138. doi: 10.1016/j.pneurobio.2016.04.001. Epub 2016 Apr 12. Review. PubMed PMID: 27084356; PubMed Central PMCID: PMC5061605.
Mladinov M, Sedmak G, Fuller HR, Babić Leko M, Mayer D, Kirincich J, Štajduhar A, Borovečki F, Hof PR, Šimić G. Gene expression profiling of the dorsolateral and medial orbitofrontal cortex in schizophrenia. Transl Neurosci. 2016;7(1):139-150. doi: 10.1515/tnsci-2016-0021. eCollection 2016. PubMed PMID: 28123834; PubMed Central PMCID: PMC5234522.
Šimić G, Babić Leko M, Wray S, Harrington C, Delalle I, Jovanov-Milošević N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik C, Hof PR. Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies. Biomolecules. 2016 Jan 6;6(1):6. doi: 10.3390/biom6010006. Review. PubMed PMID: 26751493; PubMed Central PMCID: PMC4808800.
Babić Leko M, Borovečki F, Dejanović N, Hof PR, Šimić G. Predictive Value of Cerebrospinal Fluid Visinin-Like Protein-1 Levels for Alzheimer's Disease Early Detection and Differential Diagnosis in Patients with Mild Cognitive Impairment. J Alzheimers Dis. 2016;50(3):765-78. doi: 10.3233/JAD-150705. PubMed PMID: 26836160.
Fuller HR, Slade R, Jovanov-Milošević N, Babić M, Sedmak G, Šimić G, Fuszard MA, Shirran SL, Botting CH, Gates MA. Stathmin is enriched in the developing corticospinal tract. Mol Cell Neurosci. 2015 Nov;69:12-21. doi: 10.1016/j.mcn.2015.09.003. Epub 2015 Sep 12. PubMed PMID: 26370173.
Jembrek MJ, Šimić G, Hof PR, Šegota S. Atomic force microscopy as an advanced tool in neuroscience. Transl Neurosci. 2015;6(1):117-130. doi: 10.1515/tnsci-2015-0011. eCollection 2015. Review. PubMed PMID: 28123795; PubMed Central PMCID: PMC4936619.
Jazvinšćak Jembrek M, Hof PR, Šimić G. Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation. Oxid Med Cell Longev. 2015;2015:346783. doi: 10.1155/2015/346783. Epub 2015 May 24. Review. PubMed PMID: 26090071; PubMed Central PMCID: PMC4458271.
Knezovic A, Osmanovic-Barilar J, Curlin M, Hof PR, Simic G, Riederer P, Salkovic-Petrisic M. Staging of cognitive deficits and neuropathological and ultrastructural changes in streptozotocin-induced rat model of Alzheimer's disease. J Neural Transm (Vienna). 2015 Apr;122(4):577-92. doi: 10.1007/s00702-015-1394-4. Epub 2015 Mar 26. PubMed PMID: 25808906.
Simić G, Hof PR. In search of the definitive Brodmann's map of cortical areas in human. J Comp Neurol. 2015 Jan 1;523(1):5-14. doi: 10.1002/cne.23636. Epub 2014 Jun 27. PubMed PMID: 24889330.
Babić M, Svob Štrac D, Mück-Šeler D, Pivac N, Stanić G, Hof PR, Simić G. Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease. Croat Med J. 2014 Aug 28;55(4):347-65. doi: 10.3325/cmj.2014.55.347. Review. PubMed PMID: 25165049; PubMed Central PMCID: PMC4157375.
Simic G, Babic M, Borovecki F, Hof PR. Early failure of the default-mode network and the pathogenesis of Alzheimer's disease. CNS Neurosci Ther. 2014 Jul;20(7):692-8. doi: 10.1111/cns.12260. Epub 2014 Apr 8. Review. PubMed PMID: 24712393; PubMed Central PMCID: PMC4062585.
Simic. Congenital brain anomalies and chromosomal aberrations from the Zagreb Collection of the human brains. Translational Neuroscience. 2014; doi: 10.2478/s13380-014-0231-9.
Mustapic M, Presecki P, Pivac N, Mimica N, Hof PR, Simic G, Folnegovic-Smalc V, Muck-Seler D. Genotype-independent decrease in plasma dopamine beta-hydroxylase activity in Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 1;44:94-9. doi: 10.1016/j.pnpbp.2013.02.002. Epub 2013 Feb 13. PubMed PMID: 23416088; PubMed Central PMCID: PMC3952071.
Babić M, Vogrinc Z, Diana A, Klepac N, Borovečki F, Hof PR, Simić G. Comparison of two commercial enzyme-linked immunosorbent assays for cerebrospinal fluid measurement of amyloid β1-42 and total tau. Transl Neurosci. 2013 Jun;4(2). doi: 10.2478/s13380-013-0123-4. PubMed PMID: 24376914; PubMed Central PMCID: PMC3873720.
Simic. Functional reorganization of the primary motor cortex in a patient with a large arteriovenous malformation involving the precentral gyrus. Translational Neuroscience. 2013; doi: 10.2478/s13380-013-0122-5.
Simic. Hyperphosphorylation of tau by GSK-3β in Alzheimer's disease: the interaction of Aβ and sphingolipid mediators as a therapeutic target. Translational Neuroscience. 2013; doi: 10.2478/s13380-013-0144-z.
Simic. Pathogenesis, modulation, and therapy of Alzheimer's disease: a perspective on roles of liver-X receptors. Translational Neuroscience. 2013; doi: 10.2478/s13380-013-0136-z.
Jovanov-Milošević N, Petrović D, Sedmak G, Vukšić M, Hof PR, Simić G. Human fetal tau protein isoform: possibilities for Alzheimer's disease treatment. Int J Biochem Cell Biol. 2012 Aug;44(8):1290-4. doi: 10.1016/j.biocel.2012.05.001. Epub 2012 May 15. Review. PubMed PMID: 22595282; PubMed Central PMCID: PMC3572194.
Boban M, Malojčić B, Mimica N, Vuković S, Zrilić I, Hof PR, Simić G. The reliability and validity of the mini-mental state examination in the elderly Croatian population. Dement Geriatr Cogn Disord. 2012;33(6):385-92. doi: 10.1159/000339596. Epub 2012 Jul 17. PubMed PMID: 22814030.
Simic. Pilot FMRI study of neural activation patterns induced by professional military training. Translational Neuroscience. 2012; doi: 10.2478/s13380-012-0012-2.
Petanjek Z, Judaš M, Šimic G, Rasin MR, Uylings HB, Rakic P, Kostovic I. Extraordinary neoteny of synaptic spines in the human prefrontal cortex. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13281-6. doi: 10.1073/pnas.1105108108. Epub 2011 Jul 25. PubMed PMID: 21788513; PubMed Central PMCID: PMC3156171.
Raghanti MA, Simic G, Watson S, Stimpson CD, Hof PR, Sherwood CC. Comparative analysis of the nucleus basalis of Meynert among primates. Neuroscience. 2011 Jun 16;184:1-15. doi: 10.1016/j.neuroscience.2011.04.008. Epub 2011 Apr 13. PubMed PMID: 21504783.
Judaš M, Šimić G, Petanjek Z, Jovanov-Milošević N, Pletikos M, Vasung L, Vukšić M, Kostović I. The Zagreb Collection of human brains: a unique, versatile, but underexploited resource for the neuroscience community. Ann N Y Acad Sci. 2011 May;1225 Suppl 1:E105-30. doi: 10.1111/j.1749-6632.2011.05993.x. Review. PubMed PMID: 21599691.
Simic. Giant cavernoma of the skull and skeletal-extraskeletal angiomatosis associated with paraproteinemia. Translational neuroscience. 2011; doi: 10.2478/s13380-011-0032-3.
Sarac H, Henigsberg N, Markeljević J, Pavlisa G, Hof PR, Simić G. Fragile X-premutation tremor/ataxia syndrome (FXTAS) in a young woman: clinical, genetics, MRI and 1H-MR spectroscopy correlates. Coll Antropol. 2011 Jan;35 Suppl 1:327-32. PubMed PMID: 21648356.
simic. HSV1 in Alzheimer's disease: myth or reality?. Translational neuroscience. 2011; doi: 10.2478/s13380-011-0009-2.
Polšek D, Jagatic T, Cepanec M, Hof PR, Simić G. RECENT DEVELOPMENTS IN NEUROPATHOLOGY OF AUTISM SPECTRUM DISORDERS. Transl Neurosci. 2011;2(3):256-264. doi: 10.2478/s13380-011-0024-3. PubMed PMID: 22180840; PubMed Central PMCID: PMC3237008.
Mestrović J, Bralić I, Flander GB, Jelavić M, Oreb IJ, Konstantopoulos A, Kuzman M, Malović S, Miljević-Ridicki R, Miskulin M, Mujkić A, Radonić M, Rudan V, Seso-Simić D, Simić G. [Child in contemporary Croatian society]. Lijec Vjesn. 2010 Sep-Oct;132(9-10):303-8. PubMed PMID: 21261030.
Simic. Astrocyte expression of D2-like dopamine receptors in the prefrontal cortex. Translational Neuroscience. 2010; doi: 10.2478/v10134-010-0035-6.
Simic. Treatment strategies for spinal muscular atrophy. Translational neuroscience. 2010; doi: 10.2478/v10134-010-0045-4.
Simic. Recent advances in the neurobiology of attachment behavior. Translational Neuroscience. 2010; doi: 10.2478/v10134-010-0020-0.
Simic. CSF tau proteins in differential diagnosis of dementia. Translational Neuroscience. 2010; doi: 10.2478/v10134-010-0013-z.
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