My Bibliography

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Miyaji EN, Ferreira DM, Lopes AP, Brandileone MC, Dias WO, Leite LC. Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades. Infect Immun. 2002 Sep;70(9):5086-90. doi: 10.1128/IAI.70.9.5086-5090.2002. PubMed PMID: 12183557; PubMed Central PMCID: PMC128265.

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Ferreira DM, Arêas AP, Darrieux M, Leite LC, Miyaji EN. DNA vaccines based on genetically detoxified derivatives of pneumolysin fail to protect mice against challenge with Streptococcus pneumoniae. FEMS Immunol Med Microbiol. 2006 Mar;46(2):291-7. doi: 10.1111/j.1574-695X.2006.00040.x. PubMed PMID: 16487311.

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Ferreira DM, Miyaji EN, Oliveira MLS, Darrieux M, Arêas APM, Ho PL, Leite LCC. DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein. J Med Microbiol. 2006 Apr;55(Pt 4):375-378. doi: 10.1099/jmm.0.46217-0. PubMed PMID: 16533983.

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Darrieux M, Miyaji EN, Ferreira DM, Lopes LM, Lopes AP, Ren B, Briles DE, Hollingshead SK, Leite LC. Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition. Infect Immun. 2007 Dec;75(12):5930-8. doi: 10.1128/IAI.00940-07. Epub 2007 Oct 8. PubMed PMID: 17923518; PubMed Central PMCID: PMC2168346.

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Ferreira DM, Darrieux M, Oliveira ML, Leite LC, Miyaji EN. Optimized immune response elicited by a DNA vaccine expressing pneumococcal surface protein a is characterized by a balanced immunoglobulin G1 (IgG1)/IgG2a ratio and proinflammatory cytokine production. Clin Vaccine Immunol. 2008 Mar;15(3):499-505. doi: 10.1128/CVI.00400-07. Epub 2008 Jan 9. PubMed PMID: 18184825; PubMed Central PMCID: PMC2268278.

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Campos IB, Darrieux M, Ferreira DM, Miyaji EN, Silva DA, Arêas AP, Aires KA, Leite LC, Ho PL, Oliveira ML. Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge. Microbes Infect. 2008 Apr;10(5):481-8. doi: 10.1016/j.micinf.2008.01.007. Epub 2008 Jan 20. PubMed PMID: 18403234.

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Darrieux M, Moreno AT, Ferreira DM, Pimenta FC, de Andrade ALSS, Lopes APY, Leite LCC, Miyaji EN. Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades. J Med Microbiol. 2008 Mar;57(Pt 3):273-278. doi: 10.1099/jmm.0.47661-0. PubMed PMID: 18287288.

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Ferreira DM, Darrieux M, Silva DA, Leite LC, Ferreira JM Jr, Ho PL, Miyaji EN, Oliveira ML. Characterization of protective mucosal and systemic immune responses elicited by pneumococcal surface protein PspA and PspC nasal vaccines against a respiratory pneumococcal challenge in mice. Clin Vaccine Immunol. 2009 May;16(5):636-45. doi: 10.1128/CVI.00395-08. Epub 2009 Mar 11. PubMed PMID: 19279169; PubMed Central PMCID: PMC2681601.

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Ferreira DM, Moreno AT, Cianciarullo AM, Ho PL, Oliveira ML, Miyaji EN. Comparison of the pulmonary response against lethal and non-lethal intranasal challenges with two different pneumococcal strains. Microb Pathog. 2009 Sep;47(3):157-63. doi: 10.1016/j.micpath.2009.05.005. Epub 2009 May 23. PubMed PMID: 19467320.

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Richards L, Ferreira DM, Miyaji EN, Andrew PW, Kadioglu A. The immunising effect of pneumococcal nasopharyngeal colonisation; protection against future colonisation and fatal invasive disease. Immunobiology. 2010 Apr;215(4):251-63. doi: 10.1016/j.imbio.2009.12.004. Epub 2009 Dec 28. PubMed PMID: 20071053.

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Moreno AT, Oliveira ML, Ferreira DM, Ho PL, Darrieux M, Leite LC, Ferreira JM Jr, Pimenta FC, Andrade AL, Miyaji EN. Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection. Clin Vaccine Immunol. 2010 Mar;17(3):439-46. doi: 10.1128/CVI.00430-09. Epub 2010 Jan 20. PubMed PMID: 20089795; PubMed Central PMCID: PMC2837969.

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Ferreira DM, Oliveira ML, Moreno AT, Ho PL, Briles DE, Miyaji EN. Protection against nasal colonization with Streptococcus pneumoniae by parenteral immunization with a DNA vaccine encoding PspA (Pneumococcal surface protein A). Microb Pathog. 2010 Jun;48(6):205-13. doi: 10.1016/j.micpath.2010.02.009. Epub 2010 Mar 4. PubMed PMID: 20206678.

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Oliveira ML, Miyaji EN, Ferreira DM, Moreno AT, Ferreira PC, Lima FA, Santos FL, Sakauchi MA, Takata CS, Higashi HG, Raw I, Kubrusly FS, Ho PL. Combination of pneumococcal surface protein A (PspA) with whole cell pertussis vaccine increases protection against pneumococcal challenge in mice. PLoS One. 2010 May 27;5(5):e10863. doi: 10.1371/journal.pone.0010863. PubMed PMID: 20523738; PubMed Central PMCID: PMC2877721.

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McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, Ferreira D, Smeaton S, El-Rachkidy R, McLoughlin RM, Mori A, Moran B, Fitzgerald KA, Tschopp J, Pétrilli V, Andrew PW, Kadioglu A, Lavelle EC. Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. PLoS Pathog. 2010 Nov 11;6(11):e1001191. doi: 10.1371/journal.ppat.1001191. PubMed PMID: 21085613; PubMed Central PMCID: PMC2978728.

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Hernani Mde L, Ferreira PC, Ferreira DM, Miyaji EN, Ho PL, Oliveira ML. Nasal immunization of mice with Lactobacillus casei expressing the pneumococcal surface protein C primes the immune system and decreases pneumococcal nasopharyngeal colonization in mice. FEMS Immunol Med Microbiol. 2011 Aug;62(3):263-72. doi: 10.1111/j.1574-695X.2011.00809.x. Epub 2011 May 9. PubMed PMID: 21492260.

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Ferreira DM, Jambo KC, Gordon SB. Experimental human pneumococcal carriage models for vaccine research. Trends Microbiol. 2011 Sep;19(9):464-70. doi: 10.1016/j.tim.2011.06.003. Epub 2011 Jul 23. Review. PubMed PMID: 21784641.

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Briles DE, Miyaji E, Fukuyama Y, Ferreira DM, Fujihashi K. Elicitation of mucosal immunity by proteins of Streptococcus pneumoniae. Adv Otorhinolaryngol. 2011;72:25-7. doi: 10.1159/000324589. Epub 2011 Aug 18. PubMed PMID: 21865682.

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Moreno AT, Oliveira ML, Ho PL, Vadesilho CF, Palma GM, Ferreira JM Jr, Ferreira DM, Santos SR, Martinez MB, Miyaji EN. Cross-reactivity of antipneumococcal surface protein C (PspC) antibodies with different strains and evaluation of inhibition of human complement factor H and secretory IgA binding via PspC. Clin Vaccine Immunol. 2012 Apr;19(4):499-507. doi: 10.1128/CVI.05706-11. Epub 2012 Feb 15. PubMed PMID: 22336290; PubMed Central PMCID: PMC3318277.

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Wright AK, Ferreira DM, Gritzfeld JF, Wright AD, Armitage K, Jambo KC, Bate E, El Batrawy S, Collins A, Gordon SB. Human nasal challenge with Streptococcus pneumoniae is immunising in the absence of carriage. PLoS Pathog. 2012;8(4):e1002622. doi: 10.1371/journal.ppat.1002622. Epub 2012 Apr 5. PubMed PMID: 22496648; PubMed Central PMCID: PMC3320601.

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Neill DR, Fernandes VE, Wisby L, Haynes AR, Ferreira DM, Laher A, Strickland N, Gordon SB, Denny P, Kadioglu A, Andrew PW. T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice. PLoS Pathog. 2012;8(4):e1002660. doi: 10.1371/journal.ppat.1002660. Epub 2012 Apr 19. PubMed PMID: 22563306; PubMed Central PMCID: PMC3334885.

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Lima FA, Ferreira DM, Moreno AT, Ferreira PC, Palma GM, Ferreira JM Jr, Raw I, Miyaji EN, Ho PL, Oliveira ML. Controlled inflammatory responses in the lungs are associated with protection elicited by a pneumococcal surface protein A-based vaccine against a lethal respiratory challenge with Streptococcus pneumoniae in mice. Clin Vaccine Immunol. 2012 Sep;19(9):1382-92. doi: 10.1128/CVI.00171-12. Epub 2012 Jul 3. PubMed PMID: 22761301; PubMed Central PMCID: PMC3428385.

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Vadesilho CF, Ferreira DM, Moreno AT, Chavez-Olortegui C, Machado de Avila RA, Oliveira ML, Ho PL, Miyaji EN. Characterization of the antibody response elicited by immunization with pneumococcal surface protein A (PspA) as recombinant protein or DNA vaccine and analysis of protection against an intranasal lethal challenge with Streptococcus pneumoniae. Microb Pathog. 2012 Nov-Dec;53(5-6):243-9. doi: 10.1016/j.micpath.2012.08.007. Epub 2012 Sep 7. PubMed PMID: 22981893.

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Gritzfeld JF, Wright AD, Collins AM, Pennington SH, Wright AK, Kadioglu A, Ferreira DM, Gordon SB. Experimental human pneumococcal carriage. J Vis Exp. 2013 Feb 15;(72). doi: 10.3791/50115. PubMed PMID: 23439027; PubMed Central PMCID: PMC3601207.

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Wright AK, Bangert M, Gritzfeld JF, Ferreira DM, Jambo KC, Wright AD, Collins AM, Gordon SB. Experimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung. PLoS Pathog. 2013 Mar;9(3):e1003274. doi: 10.1371/journal.ppat.1003274. Epub 2013 Mar 28. PubMed PMID: 23555269; PubMed Central PMCID: PMC3610738.

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Ferreira DM, Neill DR, Bangert M, Gritzfeld JF, Green N, Wright AK, Pennington SH, Bricio-Moreno L, Moreno AT, Miyaji EN, Wright AD, Collins AM, Goldblatt D, Kadioglu A, Gordon SB. Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults. Am J Respir Crit Care Med. 2013 Apr 15;187(8):855-64. doi: 10.1164/rccm.201212-2277OC. PubMed PMID: 23370916; PubMed Central PMCID: PMC3707375.

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Collins AM, Batrawy SE, Gordon SB, Ferreira DM. Increased IgG but normal IgA anti-pneumococcal protein antibodies in lung of HIV-infected adults. Vaccine. 2013 Aug 2;31(35):3469-72. doi: 10.1016/j.vaccine.2013.04.062. Epub 2013 May 10. PubMed PMID: 23664995; PubMed Central PMCID: PMC3740234.

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Vadesilho CF, Ferreira DM, Gordon SB, Briles DE, Moreno AT, Oliveira ML, Ho PL, Miyaji EN. Mapping of epitopes recognized by antibodies induced by immunization of mice with PspA and PspC. Clin Vaccine Immunol. 2014 Jul;21(7):940-8. doi: 10.1128/CVI.00239-14. Epub 2014 May 7. PubMed PMID: 24807052; PubMed Central PMCID: PMC4097434.

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Gritzfeld JF, Cremers AJ, Ferwerda G, Ferreira DM, Kadioglu A, Hermans PW, Gordon SB. Density and duration of experimental human pneumococcal carriage. Clin Microbiol Infect. 2014 Dec;20(12):O1145-51. doi: 10.1111/1469-0691.12752. Epub 2014 Aug 11. PubMed PMID: 24995531; PubMed Central PMCID: PMC4313687.

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Al-Salem WS, Ferreira DM, Dyer NA, Alyamani EJ, Balghonaim SM, Al-Mehna AY, Al-Zubiany S, Ibrahim el-K, Al Shahrani AM, Alkhuailed H, Aldahan MA, Al Jarallh AM, Abdelhady SS, Al-Zahrani MH, Almeida IC, Acosta-Serrano A. Detection of high levels of anti-α-galactosyl antibodies in sera of patients with Old World cutaneous leishmaniasis: a possible tool for diagnosis and biomarker for cure in an elimination setting. Parasitology. 2014 Dec;141(14):1898-903. doi: 10.1017/S0031182014001607. Epub 2014 Oct 9. PubMed PMID: 25297927.

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Cremers AJ, Zomer AL, Gritzfeld JF, Ferwerda G, van Hijum SA, Ferreira DM, Shak JR, Klugman KP, Boekhorst J, Timmerman HM, de Jonge MI, Gordon SB, Hermans PW. The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition. Microbiome. 2014;2:44. doi: 10.1186/2049-2618-2-44. eCollection 2014. PubMed PMID: 25671106; PubMed Central PMCID: PMC4323220.

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Glennie S, Gritzfeld JF, Pennington SH, Garner-Jones M, Coombes N, Hopkins MJ, Vadesilho CF, Miyaji EN, Wang D, Wright AD, Collins AM, Gordon SB, Ferreira DM. Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage. Mucosal Immunol. 2016 Jan;9(1):56-67. doi: 10.1038/mi.2015.35. Epub 2015 Apr 29. PubMed PMID: 25921341; PubMed Central PMCID: PMC4703943.

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Kunda NK, Alfagih IM, Miyaji EN, Figueiredo DB, Gonçalves VM, Ferreira DM, Dennison SR, Somavarapu S, Hutcheon GA, Saleem IY. Pulmonary dry powder vaccine of pneumococcal antigen loaded nanoparticles. Int J Pharm. 2015 Nov 30;495(2):903-12. doi: 10.1016/j.ijpharm.2015.09.034. Epub 2015 Sep 18. PubMed PMID: 26387622.

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Collins AM, Wright AD, Mitsi E, Gritzfeld JF, Hancock CA, Pennington SH, Wang D, Morton B, Ferreira DM, Gordon SB. First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial. Am J Respir Crit Care Med. 2015 Oct 1;192(7):853-8. doi: 10.1164/rccm.201503-0542OC. PubMed PMID: 26114410.

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Collins AM, Johnstone CM, Gritzfeld JF, Banyard A, Hancock CA, Wright AD, Macfarlane L, Ferreira DM, Gordon SB. Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study. J Clin Microbiol. 2016 Apr;54(4):944-9. doi: 10.1128/JCM.02008-15. Epub 2016 Jan 20. PubMed PMID: 26791364; PubMed Central PMCID: PMC4809940.

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Pennington SH, Thompson AL, Wright AK, Ferreira DM, Jambo KC, Wright AD, Faragher B, Gilmour JW, Gordon SB, Gordon MA. Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa. J Infect Dis. 2016 Jun 1;213(11):1809-19. doi: 10.1093/infdis/jiw030. Epub 2016 Jan 24. PubMed PMID: 26810369; PubMed Central PMCID: PMC4857474.

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Gordon S, Ferreira DM. When Do Coughs and Sneezes Cause Diseases?. Am J Respir Crit Care Med. 2016 Jun 15;193(12):1329-30. doi: 10.1164/rccm.201601-0130ED. PubMed PMID: 27304239.

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Mitsi E, Roche AM, Reiné J, Zangari T, Owugha JT, Pennington SH, Gritzfeld JF, Wright AD, Collins AM, van Selm S, de Jonge MI, Gordon SB, Weiser JN, Ferreira DM. Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage. Mucosal Immunol. 2017 Mar;10(2):385-394. doi: 10.1038/mi.2016.71. Epub 2016 Aug 31. PubMed PMID: 27579859; PubMed Central PMCID: PMC5332540.

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Blanchette KA, Shenoy AT, Milner J 2nd, Gilley RP, McClure E, Hinojosa CA, Kumar N, Daugherty SC, Tallon LJ, Ott S, King SJ, Ferreira DM, Gordon SB, Tettelin H, Orihuela CJ. Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization. Infect Immun. 2016 Oct;84(10):2922-32. doi: 10.1128/IAI.00277-16. Print 2016 Oct. PubMed PMID: 27481242; PubMed Central PMCID: PMC5038079.

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Morton B, Mitsi E, Pennington SH, Reiné J, Wright AD, Parker R, Welters ID, Blakey JD, Rajam G, Ades EW, Ferreira DM, Wang D, Kadioglu A, Gordon SB. Augmented Passive Immunotherapy with P4 Peptide Improves Phagocyte Activity in Severe Sepsis. Shock. 2016 Dec;46(6):635-641. doi: 10.1097/SHK.0000000000000715. PubMed PMID: 27488089.

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Pennington SH, Pojar S, Mitsi E, Gritzfeld JF, Nikolaou E, Solórzano C, Owugha JT, Masood Q, Gordon MA, Wright AD, Collins AM, Miyaji EN, Gordon SB, Ferreira DM. Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1523-1531. doi: 10.1164/rccm.201512-2467OC. PubMed PMID: 27403678; PubMed Central PMCID: PMC5215029.

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Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM. Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash. PLoS One. 2017;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017. PubMed PMID: 28107457; PubMed Central PMCID: PMC5249128.

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Zaidi SR, Collins AM, Mitsi E, Reiné J, Davies K, Wright AD, Owugha J, Fitzgerald R, Ganguli A, Gordon SB, Ferreira DM, Rylance J. Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591). BMC Pulm Med. 2017 May 5;17(1):83. doi: 10.1186/s12890-017-0421-7. PubMed PMID: 28476111; PubMed Central PMCID: PMC5420119.

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Adler H, Ferreira DM, Gordon SB, Rylance J. Pneumococcal Capsular Polysaccharide Immunity in the Elderly. Clin Vaccine Immunol. 2017 Jun;24(6). doi: 10.1128/CVI.00004-17. Print 2017 Jun. Review. PubMed PMID: 28424198; PubMed Central PMCID: PMC5461380.

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Gordon SB, Rylance J, Luck A, Jambo K, Ferreira DM, Manda-Taylor L, Bejon P, Ngwira B, Littler K, Seager Z, Gibani M, Gmeiner M, Roestenberg M, Mlombe Y, Wellcome Trust CHIM workshop participants. A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi. Wellcome Open Res. 2017;2:70. doi: 10.12688/wellcomeopenres.12256.1. eCollection 2017. PubMed PMID: 29018841; PubMed Central PMCID: PMC5627502.

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Nikolaou E, Mitsi E, Ferreira DM, Bartolo A, Leong SC. Assessing the ideal microwave duration for disinfection of sinus irrigation bottles-A quantitative study. Clin Otolaryngol. 2018 Feb;43(1):261-266. doi: 10.1111/coa.12956. Epub 2017 Sep 14. PubMed PMID: 28815972.

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Peno C, Banda DH, Jambo N, Kankwatira AM, Malamba RD, Allain TJ, Ferreira DM, Heyderman RS, Russell DG, Mwandumba HC, Jambo KC. Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults. J Infect. 2018 Feb;76(2):168-176. doi: 10.1016/j.jinf.2017.10.013. Epub 2017 Nov 29. PubMed PMID: 29197600; PubMed Central PMCID: PMC5792245.

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Jochems SP, Weiser JN, Malley R, Ferreira DM. The immunological mechanisms that control pneumococcal carriage. PLoS Pathog. 2017 Dec;13(12):e1006665. doi: 10.1371/journal.ppat.1006665. eCollection 2017 Dec. Review. PubMed PMID: 29267378; PubMed Central PMCID: PMC5739485.

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Rodrigues TC, Oliveira MLS, Soares-Schanoski A, Chavez-Rico SL, Figueiredo DB, Gonçalves VM, Ferreira DM, Kunda NK, Saleem IY, Miyaji EN. Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection. PLoS One. 2018;13(1):e0191692. doi: 10.1371/journal.pone.0191692. eCollection 2018. PubMed PMID: 29360883; PubMed Central PMCID: PMC5779684.

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Shekhar S, Khan R, Ferreira DM, Mitsi E, German E, Rørvik GH, Berild D, Schenck K, Kwon K, Petersen F. Antibodies Reactive to Commensal Streptococcus mitis Show Cross-Reactivity With Virulent Streptococcus pneumoniae Serotypes. Front Immunol. 2018;9:747. doi: 10.3389/fimmu.2018.00747. eCollection 2018. PubMed PMID: 29713324; PubMed Central PMCID: PMC5911667.

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Mitsi E, Kamng'ona R, Rylance J, Solórzano C, Jesus Reiné J, Mwandumba HC, Ferreira DM, Jambo KC. Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state. Respir Res. 2018 Apr 18;19(1):66. doi: 10.1186/s12931-018-0777-0. PubMed PMID: 29669565; PubMed Central PMCID: PMC5907303.