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von Loeffelholz O, Peña A, Drummond DR, Cross R, Moores CA. Cryo-EM Structure (4.5-Å) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance. J Mol Biol. 2019 Feb 15;431(4):864-872. doi: 10.1016/j.jmb.2019.01.011. Epub 2019 Jan 16. PubMed PMID: 30659798; PubMed Central PMCID: PMC6378684.
Cross RA. Microtubule lattice plasticity. Curr Opin Cell Biol. 2019 Feb;56:88-93. doi: 10.1016/ Epub 2018 Nov 8. Review. PubMed PMID: 30415187.
Meadows JC, Messin LJ, Kamnev A, Lancaster TC, Balasubramanian MK, Cross RA, Millar JB. Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends. EMBO Rep. 2018 Nov;19(11). doi: 10.15252/embr.201846196. Epub 2018 Sep 11. PubMed PMID: 30206188; PubMed Central PMCID: PMC6216294.
McHugh T, Drechsler H, McAinsh AD, Carter NJ, Cross RA. Kif15 functions as an active mechanical ratchet. Mol Biol Cell. 2018 Jul 15;29(13):1743-1752. doi: 10.1091/mbc.E18-03-0151. Epub 2018 May 17. PubMed PMID: 29771628; PubMed Central PMCID: PMC6080711.
Peet DR, Burroughs NJ, Cross RA. Kinesin expands and stabilizes the GDP-microtubule lattice. Nat Nanotechnol. 2018 May;13(5):386-391. doi: 10.1038/s41565-018-0084-4. Epub 2018 Mar 12. PubMed PMID: 29531331; PubMed Central PMCID: PMC5937683.
von Loeffelholz O, Venables NA, Drummond DR, Katsuki M, Cross R, Moores CA. Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics. Nat Commun. 2017 Dec 13;8(1):2110. doi: 10.1038/s41467-017-02241-5. PubMed PMID: 29235477; PubMed Central PMCID: PMC5727398.
Britto M, Goulet A, Rizvi S, von Loeffelholz O, Moores CA, Cross RA. Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7483-E7489. doi: 10.1073/pnas.1611581113. Epub 2016 Nov 9. PubMed PMID: 27834216; PubMed Central PMCID: PMC5127321.
Huang J, Chew TG, Gu Y, Palani S, Kamnev A, Martin DS, Carter NJ, Cross RA, Oliferenko S, Balasubramanian MK. Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction. Elife. 2016 Oct 13;5. doi: 10.7554/eLife.21383. PubMed PMID: 27734801; PubMed Central PMCID: PMC5077295.
Cross RA. Review: Mechanochemistry of the kinesin-1 ATPase. Biopolymers. 2016 Aug;105(8):476-82. doi: 10.1002/bip.22862. Review. PubMed PMID: 27120111; PubMed Central PMCID: PMC4924600.
Hussmann F, Drummond DR, Peet DR, Martin DS, Cross RA. Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism. Sci Rep. 2016 Feb 11;6:20653. doi: 10.1038/srep20653. PubMed PMID: 26864000; PubMed Central PMCID: PMC4749977.
Andrecka J, Ortega Arroyo J, Lewis K, Cross RA, Kukura P. Label-free Imaging of Microtubules with Sub-nm Precision Using Interferometric Scattering Microscopy. Biophys J. 2016 Jan 5;110(1):214-7. doi: 10.1016/j.bpj.2015.10.055. PubMed PMID: 26745424; PubMed Central PMCID: PMC4806212.
Cross RA, McAinsh A. Prime movers: the mechanochemistry of mitotic kinesins. Nat Rev Mol Cell Biol. 2014 Apr;15(4):257-71. doi: 10.1038/nrm3768. Review. PubMed PMID: 24651543.
Klejnot M, Falnikar A, Ulaganathan V, Cross RA, Baas PW, Kozielski F. The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development. Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):123-33. doi: 10.1107/S1399004713028721. Epub 2013 Dec 24. PubMed PMID: 24419385; PubMed Central PMCID: PMC3919264.
Katsuki M, Drummond DR, Cross RA. Ectopic A-lattice seams destabilize microtubules. Nat Commun. 2014;5:3094. doi: 10.1038/ncomms4094. PubMed PMID: 24463734; PubMed Central PMCID: PMC3921467.
Wollman AJ, Sanchez-Cano C, Carstairs HM, Cross RA, Turberfield AJ. Transport and self-organization across different length scales powered by motor proteins and programmed by DNA. Nat Nanotechnol. 2014 Jan;9(1):44-7. doi: 10.1038/nnano.2013.230. Epub 2013 Nov 10. PubMed PMID: 24213281; PubMed Central PMCID: PMC3883648.
Carter NJ, Cross RA. Kinesin backsteps. Biochem Soc Trans. 2012 Apr;40(2):400-3. doi: 10.1042/BST20120008. Review. PubMed PMID: 22435819.
Erent M, Drummond DR, Cross RA. S. pombe kinesins-8 promote both nucleation and catastrophe of microtubules. PLoS One. 2012;7(2):e30738. doi: 10.1371/journal.pone.0030738. Epub 2012 Feb 20. PubMed PMID: 22363481; PubMed Central PMCID: PMC3282699.
Kaseda K, McAinsh AD, Cross RA. Dual pathway spindle assembly increases both the speed and the fidelity of mitosis. Biol Open. 2012 Jan 15;1(1):12-8. doi: 10.1242/bio.2011012. Epub 2011 Oct 24. PubMed PMID: 23213363; PubMed Central PMCID: PMC3507165.
Cross RA, McAinsh AD, Straube A. Mechanochemical cell biology. Semin Cell Dev Biol. 2011 Dec;22(9):913-5. doi: 10.1016/j.semcdb.2011.10.002. Epub 2011 Oct 7. PubMed PMID: 22001112.
Grant BJ, Gheorghe DM, Zheng W, Alonso M, Huber G, Dlugosz M, McCammon JA, Cross RA. Electrostatically biased binding of kinesin to microtubules. PLoS Biol. 2011 Nov;9(11):e1001207. doi: 10.1371/journal.pbio.1001207. Epub 2011 Nov 29. PubMed PMID: 22140358; PubMed Central PMCID: PMC3226556.
Katsuki M, Muto E, Cross RA. Preparation of dual-color polarity-marked fluorescent microtubule seeds. Methods Mol Biol. 2011;777:117-26. doi: 10.1007/978-1-61779-252-6_9. PubMed PMID: 21773925.
Drummond DR, Kain S, Newcombe A, Hoey C, Katsuki M, Cross RA. Purification of tubulin from the fission yeast Schizosaccharomyces pombe. Methods Mol Biol. 2011;777:29-55. doi: 10.1007/978-1-61779-252-6_3. PubMed PMID: 21773919.
Cross RA. Kinesin-14: the roots of reversal. BMC Biol. 2010 Aug 16;8:107. doi: 10.1186/1741-7007-8-107. PubMed PMID: 20731883; PubMed Central PMCID: PMC2922096.
Katsuki M, Drummond DR, Osei M, Cross RA. Mal3 masks catastrophe events in Schizosaccharomyces pombe microtubules by inhibiting shrinkage and promoting rescue. J Biol Chem. 2009 Oct 23;284(43):29246-50. doi: 10.1074/jbc.C109.052159. Epub 2009 Sep 9. PubMed PMID: 19740752; PubMed Central PMCID: PMC2764634.
Kaseda K, McAinsh AD, Cross RA. Walking, hopping, diffusing and braking modes of kinesin-5. Biochem Soc Trans. 2009 Oct;37(Pt 5):1045-9. doi: 10.1042/BST0371045. PubMed PMID: 19754449.
Braun M, Drummond DR, Cross RA, McAinsh AD. The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism. Nat Cell Biol. 2009 Jun;11(6):724-30. doi: 10.1038/ncb1878. Epub 2009 May 10. PubMed PMID: 19430466.
des Georges A, Katsuki M, Drummond DR, Osei M, Cross RA, Amos LA. Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice. Nat Struct Mol Biol. 2008 Oct;15(10):1102-8. doi: 10.1038/nsmb.1482. Epub 2008 Sep 14. PubMed PMID: 18794845; PubMed Central PMCID: PMC2575238.
Cross R. Single molecule for the people. Nat Cell Biol. 2008 Sep;10(9):1014. doi: 10.1038/ncb0908-1014. PubMed PMID: 18758487.
Kaseda K, Crevel I, Hirose K, Cross RA. Single-headed mode of kinesin-5. EMBO Rep. 2008 Aug;9(8):761-5. doi: 10.1038/embor.2008.96. Epub 2008 Jun 13. PubMed PMID: 18552767; PubMed Central PMCID: PMC2515207.
Dunn S, Morrison EE, Liverpool TB, Molina-París C, Cross RA, Alonso MC, Peckham M. Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells. J Cell Sci. 2008 Apr 1;121(Pt 7):1085-95. doi: 10.1242/jcs.026492. Epub 2008 Mar 11. PubMed PMID: 18334549.
Grant BJ, McCammon JA, Caves LS, Cross RA. Multivariate analysis of conserved sequence-structure relationships in kinesins: coupling of the active site and a tubulin-binding sub-domain. J Mol Biol. 2007 May 18;368(5):1231-48. doi: 10.1016/j.jmb.2007.02.049. Epub 2007 Mar 30. PubMed PMID: 17399740.
Alonso MC, Drummond DR, Kain S, Hoeng J, Amos L, Cross RA. An ATP gate controls tubulin binding by the tethered head of kinesin-1. Science. 2007 Apr 6;316(5821):120-3. doi: 10.1126/science.1136985. PubMed PMID: 17412962; PubMed Central PMCID: PMC2504013.
Moores CA, Perderiset M, Kappeler C, Kain S, Drummond D, Perkins SJ, Chelly J, Cross R, Houdusse A, Francis F. Distinct roles of doublecortin modulating the microtubule cytoskeleton. EMBO J. 2006 Oct 4;25(19):4448-57. doi: 10.1038/sj.emboj.7601335. Epub 2006 Sep 7. PubMed PMID: 16957770; PubMed Central PMCID: PMC1590004.
Skoufias DA, DeBonis S, Saoudi Y, Lebeau L, Crevel I, Cross R, Wade RH, Hackney D, Kozielski F. S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem. 2006 Jun 30;281(26):17559-69. doi: 10.1074/jbc.M511735200. Epub 2006 Feb 28. PubMed PMID: 16507573.
Cross RA. Myosin's mechanical ratchet. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):8911-2. doi: 10.1073/pnas.0603213103. Epub 2006 Jun 5. PubMed PMID: 16754855; PubMed Central PMCID: PMC1482537.
Carter NJ, Cross RA. Kinesin's moonwalk. Curr Opin Cell Biol. 2006 Feb;18(1):61-7. doi: 10.1016/ Epub 2005 Dec 19. Review. PubMed PMID: 16361092.
Yajima J, Cross RA. A torque component in the kinesin-1 power stroke. Nat Chem Biol. 2005 Nov;1(6):338-41. doi: 10.1038/nchembio740. Epub 2005 Oct 9. PubMed PMID: 16408073.
Carter NJ, Cross RA. Mechanics of the kinesin step. Nature. 2005 May 19;435(7040):308-12. doi: 10.1038/nature03528. PubMed PMID: 15902249.
Eickel V, Drummond D, Carter N, Lockhart A, Jones JK, Cross R. Kinesin heads fused to hinge-free myosin tails drive efficient motility. FEBS Lett. 2004 Jul 2;569(1-3):54-8. doi: 10.1016/j.febslet.2004.05.050. PubMed PMID: 15225608.
Crevel IM, Alonso MC, Cross RA. Monastrol stabilises an attached low-friction mode of Eg5. Curr Biol. 2004 Jun 8;14(11):R411-2. doi: 10.1016/j.cub.2004.05.030. PubMed PMID: 15182685.
Cross RA. The kinetic mechanism of kinesin. Trends Biochem Sci. 2004 Jun;29(6):301-9. doi: 10.1016/j.tibs.2004.04.010. Review. PubMed PMID: 15276184.
Cross RA. Molecular motors: Dynein's gearbox. Curr Biol. 2004 May 4;14(9):R355-6. doi: 10.1016/j.cub.2004.04.026. Review. PubMed PMID: 15120091.
Cross RA. Molecular motors: kinesin's interesting limp. Curr Biol. 2004 Feb 17;14(4):R158-9. Review. PubMed PMID: 15027469.
Crevel IM, Nyitrai M, Alonso MC, Weiss S, Geeves MA, Cross RA. What kinesin does at roadblocks: the coordination mechanism for molecular walking. EMBO J. 2004 Jan 14;23(1):23-32. doi: 10.1038/sj.emboj.7600042. Epub 2003 Dec 18. PubMed PMID: 14685258; PubMed Central PMCID: PMC1271674.
DeBonis S, Simorre JP, Crevel I, Lebeau L, Skoufias DA, Blangy A, Ebel C, Gans P, Cross R, Hackney DD, Wade RH, Kozielski F. Interaction of the mitotic inhibitor monastrol with human kinesin Eg5. Biochemistry. 2003 Jan 21;42(2):338-49. doi: 10.1021/bi026716j. PubMed PMID: 12525161.
Yajima J, Alonso MC, Cross RA, Toyoshima YY. Direct long-term observation of kinesin processivity at low load. Curr Biol. 2002 Feb 19;12(4):301-6. doi: 10.1016/s0960-9822(01)00683-2. PubMed PMID: 11864570.
Krylyshkina O, Kaverina I, Kranewitter W, Steffen W, Alonso MC, Cross RA, Small JV. Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J Cell Biol. 2002 Jan 21;156(2):349-59. doi: 10.1083/jcb.200105051. Epub 2002 Jan 21. PubMed PMID: 11807097; PubMed Central PMCID: PMC2199234.
Kallipolitou A, Deluca D, Majdic U, Lakämper S, Cross R, Meyhöfer E, Moroder L, Schliwa M, Woehlke G. Unusual properties of the fungal conventional kinesin neck domain from Neurospora crassa. EMBO J. 2001 Nov 15;20(22):6226-35. doi: 10.1093/emboj/20.22.6226. PubMed PMID: 11707394; PubMed Central PMCID: PMC125726.
Rogers KR, Weiss S, Crevel I, Brophy PJ, Geeves M, Cross R. KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry. EMBO J. 2001 Sep 17;20(18):5101-13. doi: 10.1093/emboj/20.18.5101. PubMed PMID: 11566875; PubMed Central PMCID: PMC125638.
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