Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation.
Sci Rep.
2018 Jan 23;8(1):1468. doi: 10.1038/s41598-018-19660-z. PubMed PMID:
29362439; PubMed Central PMCID:
PMC5780492.
Multiscalar genetic pathway modeling with hybrid Bayesian networks.
Wiley Interdisciplinary Reviews: Computational Statistics. 2019; :e1479. doi: 10.1002/wics.1479.
Systems Genetics Analysis of Molecular Pathways Underlying Ethanol-Induced Behavioral Phenotypes. Biomedical Science and Engineering Conference - Biomedical Research and Analysis in Neuroscience (BRAiN); 2010. Available from: http://ieeexplore.ieee.org/document/5510821/. DOI: 10.1109/BSEC.2010.5510821.
Precise Network Modeling of Systems Genetics Data Using the Bayesian Network Webserver.
Methods Mol Biol.
2017;1488:319-335. doi: 10.1007/978-1-4939-6427-7_15. PubMed PMID:
27933532.
PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits.
Nucleic Acids Res.
2012 Jan;40(Database issue):D216-21. doi: 10.1093/nar/gkr1026. Epub 2011 Nov 10. PubMed PMID:
22080514; PubMed Central PMCID:
PMC3245163.
Bayesian Network Webserver: a comprehensive tool for biological network modeling.
Bioinformatics.
2013 Nov 1;29(21):2801-3. doi: 10.1093/bioinformatics/btt472. Epub 2013 Aug 21. PubMed PMID:
23969134.
Treatment- and population-dependent activity patterns of behavioral and expression QTLs.
PLoS One.
2012;7(2):e31805. doi: 10.1371/journal.pone.0031805. Epub 2012 Feb 16. PubMed PMID:
22359631; PubMed Central PMCID:
PMC3281015.
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes.
PLoS One.
2012;7(10):e47137. doi: 10.1371/journal.pone.0047137. Epub 2012 Oct 16. PubMed PMID:
23091610; PubMed Central PMCID:
PMC3473044.
CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization.
Nucleic Acids Res.
2013 Jan;41(Database issue):D188-94. doi: 10.1093/nar/gks1165. Epub 2012 Nov 27. PubMed PMID:
23193294; PubMed Central PMCID:
PMC3531215.
Functional Analysis of Genetic Variants and Somatic Mutations Impacting MicroRNA-Target Recognition: Bioinformatics Resources.
Methods Mol Biol.
2019;1970:101-120. doi: 10.1007/978-1-4939-9207-2_8. PubMed PMID:
30963491.
GeneInfoViz: constructing and visualizing gene relation networks.
In Silico Biol.
2004;4(3):323-33. PubMed PMID:
15724283.
The Genetic Dissection of Ace2 Expression Variation in the Heart of Murine Genetic Reference Population.
Front Cardiovasc Med.
2020;7:582949. doi: 10.3389/fcvm.2020.582949. eCollection 2020. PubMed PMID:
33330645; PubMed Central PMCID:
PMC7714829.
Torsional relaxation for biopolymers.
J Comput Biol.
1998 Winter;5(4):655-65. doi: 10.1089/cmb.1998.5.655. PubMed PMID:
10072082.
MRI Brain Image Segmentation for Spotting Tumors Using Improved Mountain Clustering Approach. Washington DC, USA: Applied Imagery Pattern Recognition (AIPR): Vision: Humans, Animals, and Machines; 2009. Available from: http://ieeexplore.ieee.org/document/5466301/. DOI: 10.1109/AIPR.2009.5466301.
Hausdorff Distance and Global Silhouette Index as Novel Measures for Estimating Quality of Biclusters. IEEE International Conference on Bioinformatics and Biomedicine (BIBM).; 2015. Available from: ieeexplore.ieee.org/document/7359691/. .
Comparison of biclustering algorithms. International Conference on Systems in Medicine and Biology.; 2010. Available from: http://ieeexplore.ieee.org/document/5735351/. .
Molecular dynamics simulation of protein folding with supersecondary structure constraints.
J Protein Chem.
1998 Nov;17(8):765-9. doi: 10.1023/a:1020722117182. PubMed PMID:
9988523.
Feature Learning using Stacked Autoencoder for Shared and Multimodal Fusion of Medical Images
.
In:
Computational Intelligence: Theories, Applications and Future Directions.
Verma NK, Ghosh A, editors.
Singapore: Springer; 2019. 53-66p.
Layerwise feature selection in Stacked Sparse Auto-Encoder for tumor type prediction. IEEE International Conference on Bioinformatics and Biomedicine (BIBM).; 2016. Available from: http://ieeexplore.ieee.org/document/7822750/. .
Optimal Feature Selection using Fuzzy Combination of Feature Subset for Transcriptome Data.
IEEE International Conference on Fuzzy Systems (FUZZ-IEEE). 2018; doi: 10.1109/FUZZ-IEEE.2018.8491683.
Feature Ranking using Robust Fuzzy Score Function for Gene Expression Data.
IEEE International Conference on Fuzzy Systems (FUZZ-IEEE). 2019; doi: 10.1109/FUZZ-IEEE.2019.8858907.
Type-2 Fuzzy PCA Approach in Extracting Salient Features for Molecular Cancer Diagnostics and Prognostics.
IEEE Trans Nanobioscience.
2019 Jul;18(3):482-489. doi: 10.1109/TNB.2019.2917814. Epub 2019 May 20. PubMed PMID:
31107656.
Transfer Learning for Molecular Cancer Classification Using Deep Neural Networks.
IEEE/ACM Trans Comput Biol Bioinform.
2019 Nov-Dec;16(6):2089-2100. doi: 10.1109/TCBB.2018.2822803. Epub 2018 Apr 4. PubMed PMID:
29993662.
Autosomal similarity revealed by eukaryotic genomic comparison.
J Biol Phys.
2004 Jan;30(4):305-12. doi: 10.1007/s10867-004-0996-0. PubMed PMID:
23345874; PubMed Central PMCID:
PMC3456315.
Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients.
Sci Rep.
2019 Aug 2;9(1):11270. doi: 10.1038/s41598-019-47703-6. PubMed PMID:
31375728; PubMed Central PMCID:
PMC6677896.
Host genetics and Chlamydia disease: prediction and validation of disease severity mechanisms.
PLoS One.
2012;7(3):e33781. doi: 10.1371/journal.pone.0033781. Epub 2012 Mar 16. PubMed PMID:
22438999; PubMed Central PMCID:
PMC3306297.
Proteome-wide analysis of protein function composition reveals the clustering and phylogenetic properties of organisms.
Mol Phylogenet Evol.
2002 Oct;25(1):101-11. doi: 10.1016/s1055-7903(02)00354-8. PubMed PMID:
12383754.
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits.
Hum Mol Genet.
2006 Feb 1;15(3):481-92. doi: 10.1093/hmg/ddi462. Epub 2005 Dec 21. PubMed PMID:
16371421.
Inferring gene transcriptional modulatory relations: a genetical genomics approach.
Hum Mol Genet.
2005 May 1;14(9):1119-25. doi: 10.1093/hmg/ddi124. Epub 2005 Mar 16. PubMed PMID:
15772094.
Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray.
Nucleic Acids Res.
2006;34(10):2976-83. doi: 10.1093/nar/gkl371. Print 2006. PubMed PMID:
16738136; PubMed Central PMCID:
PMC1474057.
CbGRiTS: cerebellar gene regulation in time and space.
Dev Biol.
2015 Jan 1;397(1):18-30. doi: 10.1016/j.ydbio.2014.09.032. Epub 2014 Oct 23. PubMed PMID:
25446528; NIHMSID:NIHMS639544.
Deep transfer learning for reducing health care disparities arising from biomedical data inequality.
Nat Commun.
2020 Oct 12;11(1):5131. doi: 10.1038/s41467-020-18918-3. PubMed PMID:
33046699; PubMed Central PMCID:
PMC7552387.
miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival.
PLoS One.
2013;8(4):e60888. doi: 10.1371/journal.pone.0060888. Print 2013. PubMed PMID:
23637774; PubMed Central PMCID:
PMC3630177.
Genetic control of weight loss during pneumonic Burkholderia pseudomallei infection.
Pathog Dis.
2014 Jul;71(2):249-64. doi: 10.1111/2049-632X.12172. Epub 2014 Apr 22. PubMed PMID:
24687986; PubMed Central PMCID:
PMC4107055.
Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression.
Genome Res.
2006 Jan;16(1):20-9. doi: 10.1101/gr.4139206. Epub 2005 Dec 12. PubMed PMID:
16344563; PubMed Central PMCID:
PMC1356125.
Microarrays and Transcription Networks
.
In:
Elucidating gene regulatory networks underlying complex phenotypes: Genetical genomics and Bayesian network.
Shannon F, editor.
Austin, TX: Landes Bioscience; 2006. 114-126p.
Gene Discovery for Disease Models Bioinformatics
.
In:
Tools for Gene Function Prediction.
Gu W, editor.
Hoboken, New Jersey: John Wiley & Sons, Inc.; 2012. 93-110p.
Current Topics in Human Genetics: Studies of Complex Diseases
.
In:
Bridging Genotype and Phenotype: Causal Pathways from DNA to Complex Traits.
Deng H, editor.
New Jersey: World Scientific; 2007. 433-448p.
Integrated analysis of microarray data and gene function information.
OMICS.
2004 Summer;8(2):106-17. doi: 10.1089/1536231041388320. PubMed PMID:
15268770.
Protein folding simulation with genetic algorithm and supersecondary structure constraints.
Proteins.
1998 May 15;31(3):247-57. PubMed PMID:
9593196.
Multiple-sequence information provides protection against mis-specified potential energy functions in the lattice model of proteins.
Phys Rev Lett.
2000 Dec 11;85(24):5242-5. doi: 10.1103/PhysRevLett.85.5242. PubMed PMID:
11102231.
Molecular dynamic simulation of chaperonin-mediated protein folding.
J Protein Chem.
1998 May;17(4):377-80. doi: 10.1023/a:1022511417343. PubMed PMID:
9619590.
The coevolution of cell senescence and diploid sexual reproduction in unicellular organisms.
Proc Natl Acad Sci U S A.
2000 Mar 28;97(7):3330-5. doi: 10.1073/pnas.97.7.3330. PubMed PMID:
10737794; PubMed Central PMCID:
PMC16239.
Recombinatoric exploration of novel folded structures: a heteropolymer-based model of protein evolutionary landscapes.
Proc Natl Acad Sci U S A.
2002 Jan 22;99(2):809-14. doi: 10.1073/pnas.022240299. PubMed PMID:
11805332; PubMed Central PMCID:
PMC117387.
In silico mapping of polymorphic miRNA-mRNA interactions in autoimmune thyroid diseases.
Autoimmunity.
2014 Aug;47(5):327-33. doi: 10.3109/08916934.2014.893575. Epub 2014 Mar 10. PubMed PMID:
24611733.
Pre-transplant predictors of one yr weight gain after kidney transplantation.
Clin Transplant.
2014 Nov;28(11):1271-8. doi: 10.1111/ctr.12456. PubMed PMID:
25159302; PubMed Central PMCID:
PMC4576829.
Knowledge-based analysis of functional impacts of mutations in microRNA seed regions.
J Biosci.
2015 Oct;40(4):791-8. doi: 10.1007/s12038-015-9560-2. PubMed PMID:
26564979.
PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways.
Nucleic Acids Res.
2014 Jan;42(Database issue):D86-91. doi: 10.1093/nar/gkt1028. Epub 2013 Oct 24. PubMed PMID:
24163105; PubMed Central PMCID:
PMC3965097.
Systematic Prediction of the Impacts of Mutations in MicroRNA Seed Sequences.
J Integr Bioinform.
2017 May 18;14(1). doi: 10.1515/jib-2017-0001. PubMed PMID:
28637929; PubMed Central PMCID:
PMC6042800.
A GPU-accelerated algorithm for biclustering analysis and detection of condition-dependent coexpression network modules.
Sci Rep.
2017 Jun 23;7(1):4162. doi: 10.1038/s41598-017-04070-4. PubMed PMID:
28646174; PubMed Central PMCID:
PMC5482832.
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