My Bibliography

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Seydoux G, Greenwald I. Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell. 1989 Jun 30;57(7):1237-45. doi: 10.1016/0092-8674(89)90060-3. PubMed PMID: 2736627.

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Seydoux G, Schedl T, Greenwald I. Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans. Cell. 1990 Jun 15;61(6):939-51. doi: 10.1016/0092-8674(90)90060-r. PubMed PMID: 2350786.

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Greenwald I, Seydoux G. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature. 1990 Jul 12;346(6280):197-9. doi: 10.1038/346197a0. PubMed PMID: 2164160.

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DeVoti J, Seydoux G, Beach D, McLeod M. Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis. EMBO J. 1991 Dec;10(12):3759-68. doi: 10.1002/j.1460-2075.1991.tb04945.x. PubMed PMID: 1657594; PubMed Central PMCID: PMC453112.

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Seydoux G, Savage C, Greenwald I. Isolation and characterization of mutations causing abnormal eversion of the vulva in Caenorhabditis elegans. Dev Biol. 1993 Jun;157(2):423-36. doi: 10.1006/dbio.1993.1146. PubMed PMID: 8500652.

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Seydoux G, Fire A. Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans. Development. 1994 Oct;120(10):2823-34. doi: 10.1242/dev.120.10.2823. PubMed PMID: 7607073; NIHMSID:NIHMS528751.

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Seydoux G, Fire A. Whole-mount in situ hybridization for the detection of RNA in Caenorhabditis elegans embryos. Methods Cell Biol. 1995;48:323-37. doi: 10.1016/s0091-679x(08)61394-1. Review. PubMed PMID: 8531733; NIHMSID:NIHMS528761.

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Seydoux G, Mello CC, Pettitt J, Wood WB, Priess JR, Fire A. Repression of gene expression in the embryonic germ lineage of C. elegans. Nature. 1996 Aug 22;382(6593):713-6. doi: 10.1038/382713a0. PubMed PMID: 8751441; NIHMSID:NIHMS528729.

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Seydoux G. Mechanisms of translational control in early development. Curr Opin Genet Dev. 1996 Oct;6(5):555-61. doi: 10.1016/s0959-437x(96)80083-9. Review. PubMed PMID: 8939728.

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Seydoux G, Dunn MA. Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila melanogaster. Development. 1997 Jun;124(11):2191-201. doi: 10.1242/dev.124.11.2191. PubMed PMID: 9187145.

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Prasad BC, Ye B, Zackhary R, Schrader K, Seydoux G, Reed RR. unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors. Development. 1998 Apr;125(8):1561-8. doi: 10.1242/dev.125.8.1561. PubMed PMID: 9502737.

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Tenenhaus C, Schubert C, Seydoux G. Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans. Dev Biol. 1998 Aug 15;200(2):212-24. doi: 10.1006/dbio.1998.8940. PubMed PMID: 9705228.

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Batchelder C, Dunn MA, Choy B, Suh Y, Cassie C, Shim EY, Shin TH, Mello C, Seydoux G, Blackwell TK. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes Dev. 1999 Jan 15;13(2):202-12. doi: 10.1101/gad.13.2.202. PubMed PMID: 9925644; PubMed Central PMCID: PMC316391.

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Seydoux G, Strome S. Launching the germline in Caenorhabditis elegans: regulation of gene expression in early germ cells. Development. 1999 Aug;126(15):3275-83. doi: 10.1242/dev.126.15.3275. Review. PubMed PMID: 10393107.

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Subramaniam K, Seydoux G. nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans. Development. 1999 Nov;126(21):4861-71. doi: 10.1242/dev.126.21.4861. PubMed PMID: 10518502.

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Reese KJ, Dunn MA, Waddle JA, Seydoux G. Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains. Mol Cell. 2000 Aug;6(2):445-55. doi: 10.1016/s1097-2765(00)00043-5. PubMed PMID: 10983990.

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Wallenfang MR, Seydoux G. Polarization of the anterior-posterior axis of C. elegans is a microtubule-directed process. Nature. 2000 Nov 2;408(6808):89-92. doi: 10.1038/35040562. PubMed PMID: 11081513.

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Halpern M, Seydoux G. Embryo emergent: elucidating the cell biology of development. The Santa Cruz Conference on Developmental Biology 2000. EMBO Rep. 2000 Dec;1(6):469-72. doi: 10.1093/embo-reports/kvd115. PubMed PMID: 11263487; PubMed Central PMCID: PMC1083787.

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Golden A, Sadler PL, Wallenfang MR, Schumacher JM, Hamill DR, Bates G, Bowerman B, Seydoux G, Shakes DC. Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans. J Cell Biol. 2000 Dec 25;151(7):1469-82. doi: 10.1083/jcb.151.7.1469. PubMed PMID: 11134076; PubMed Central PMCID: PMC2150685.

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Seydoux G, Schedl T. The germline in C. elegans: origins, proliferation, and silencing. Int Rev Cytol. 2001;203:139-85. doi: 10.1016/s0074-7696(01)03006-6. Review. PubMed PMID: 11131515.

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Tenenhaus C, Subramaniam K, Dunn MA, Seydoux G. PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans. Genes Dev. 2001 Apr 15;15(8):1031-40. doi: 10.1101/gad.876201. PubMed PMID: 11316796; PubMed Central PMCID: PMC312670.

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Strome S, Powers J, Dunn M, Reese K, Malone CJ, White J, Seydoux G, Saxton W. Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Mol Biol Cell. 2001 Jun;12(6):1751-64. doi: 10.1091/mbc.12.6.1751. PubMed PMID: 11408582; PubMed Central PMCID: PMC37338.

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Wallenfang MR, Seydoux G. cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5527-32. doi: 10.1073/pnas.082618399. PubMed PMID: 11960010; PubMed Central PMCID: PMC122803.

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Pellettieri J, Seydoux G. Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences. Science. 2002 Dec 6;298(5600):1946-50. doi: 10.1126/science.1072162. Review. PubMed PMID: 12471246.

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Subramaniam K, Seydoux G. Dedifferentiation of primary spermatocytes into germ cell tumors in C. elegans lacking the pumilio-like protein PUF-8. Curr Biol. 2003 Jan 21;13(2):134-9. doi: 10.1016/s0960-9822(03)00005-8. PubMed PMID: 12546787.

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Cuenca AA, Schetter A, Aceto D, Kemphues K, Seydoux G. Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases. Development. 2003 Apr;130(7):1255-65. doi: 10.1242/dev.00284. PubMed PMID: 12588843; PubMed Central PMCID: PMC1761648.

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DeRenzo C, Reese KJ, Seydoux G. Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation. Nature. 2003 Aug 7;424(6949):685-9. doi: 10.1038/nature01887. Epub 2003 Jul 23. PubMed PMID: 12894212; PubMed Central PMCID: PMC1892537.

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Pellettieri J, Reinke V, Kim SK, Seydoux G. Coordinate activation of maternal protein degradation during the egg-to-embryo transition in C. elegans. Dev Cell. 2003 Sep;5(3):451-62. doi: 10.1016/s1534-5807(03)00231-4. PubMed PMID: 12967564; NIHMSID:NIHMS15012.

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DeRenzo C, Seydoux G. A clean start: degradation of maternal proteins at the oocyte-to-embryo transition. Trends Cell Biol. 2004 Aug;14(8):420-6. doi: 10.1016/j.tcb.2004.07.005. Review. PubMed PMID: 15308208.

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Seydoux G. Surfing the actomyosin wave: polarization of the C. elegans zygote. Dev Cell. 2004 Sep;7(3):285-6. doi: 10.1016/j.devcel.2004.08.016. PubMed PMID: 15363402.

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Stitzel ML, Pellettieri J, Seydoux G. The C. elegans DYRK Kinase MBK-2 Marks Oocyte Proteins for Degradation in Response to Meiotic Maturation. Curr Biol. 2006 Jan 10;16(1):56-62. doi: 10.1016/j.cub.2005.11.063. Epub 2005 Dec 15. PubMed PMID: 16338136.

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Hao Y, Boyd L, Seydoux G. Stabilization of cell polarity by the C. elegans RING protein PAR-2. Dev Cell. 2006 Feb;10(2):199-208. doi: 10.1016/j.devcel.2005.12.015. PubMed PMID: 16459299; PubMed Central PMCID: PMC1712613.

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Seydoux G. The 2006 Genetics Society of America Medal. Victor Ambros. Genetics. 2006 Feb;172(2):721-2. doi: 10.1534/genetics.104.17222. PubMed PMID: 16505214; PubMed Central PMCID: PMC1456236.

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D'Agostino I, Merritt C, Chen PL, Seydoux G, Subramaniam K. Translational repression restricts expression of the C. elegans Nanos homolog NOS-2 to the embryonic germline. Dev Biol. 2006 Apr 1;292(1):244-52. doi: 10.1016/j.ydbio.2005.11.046. Epub 2006 Feb 24. PubMed PMID: 16499902.

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Gallo CM, Seydoux G. Toti "potent" repressors. Bioessays. 2006 Sep;28(9):865-7. doi: 10.1002/bies.20454. PubMed PMID: 16937341.

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Seydoux G, Braun RE. Pathway to totipotency: lessons from germ cells. Cell. 2006 Dec 1;127(5):891-904. doi: 10.1016/j.cell.2006.11.016. Review. PubMed PMID: 17129777.

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Stitzel ML, Seydoux G. Regulation of the oocyte-to-zygote transition. Science. 2007 Apr 20;316(5823):407-8. doi: 10.1126/science.1138236. Review. PubMed PMID: 17446393.

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Stitzel ML, Cheng KC, Seydoux G. Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition. Curr Biol. 2007 Sep 18;17(18):1545-54. doi: 10.1016/j.cub.2007.08.049. PubMed PMID: 17869113.

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Motegi F, Seydoux G. Revisiting the role of microtubules in C. elegans polarity. J Cell Biol. 2007 Nov 5;179(3):367-9. doi: 10.1083/jcb.200710062. PubMed PMID: 17984317; PubMed Central PMCID: PMC2064782.

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Lee MH, Hook B, Pan G, Kershner AM, Merritt C, Seydoux G, Thomson JA, Wickens M, Kimble J. Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS Genet. 2007 Dec 28;3(12):e233. doi: 10.1371/journal.pgen.0030233. PubMed PMID: 18166083; PubMed Central PMCID: PMC2323325.

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Ghosh D, Seydoux G. Inhibition of transcription by the Caenorhabditis elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation. Genetics. 2008 Jan;178(1):235-43. doi: 10.1534/genetics.107.083212. PubMed PMID: 18202370; PubMed Central PMCID: PMC2206074.

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Merritt C, Rasoloson D, Ko D, Seydoux G. 3' UTRs are the primary regulators of gene expression in the C. elegans germline. Curr Biol. 2008 Oct 14;18(19):1476-82. doi: 10.1016/j.cub.2008.08.013. Epub 2008 Sep 25. PubMed PMID: 18818082; PubMed Central PMCID: PMC2585380.

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Gallo CM, Munro E, Rasoloson D, Merritt C, Seydoux G. Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos. Dev Biol. 2008 Nov 1;323(1):76-87. doi: 10.1016/j.ydbio.2008.07.008. Epub 2008 Jul 16. PubMed PMID: 18692039.

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Nakamura A, Seydoux G. Less is more: specification of the germline by transcriptional repression. Development. 2008 Dec;135(23):3817-27. doi: 10.1242/dev.022434. Review. PubMed PMID: 18997110.

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Cheng KC, Klancer R, Singson A, Seydoux G. Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition. Cell. 2009 Oct 30;139(3):560-72. doi: 10.1016/j.cell.2009.08.047. PubMed PMID: 19879842; PubMed Central PMCID: PMC2790168.

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Merritt C, Seydoux G. Transgenic solutions for the germline. WormBook. 2010 Feb 8;:1-21. doi: 10.1895/wormbook.1.148.1. Review. PubMed PMID: 20169625; PubMed Central PMCID: PMC4966531.

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Zonies S, Motegi F, Hao Y, Seydoux G. Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2. Development. 2010 May;137(10):1669-77. doi: 10.1242/dev.045823. Epub 2010 Apr 14. PubMed PMID: 20392744; PubMed Central PMCID: PMC2860249.

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Voronina E, Seydoux G. The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules. Development. 2010 May;137(9):1441-50. doi: 10.1242/dev.047654. Epub 2010 Mar 24. PubMed PMID: 20335358; PubMed Central PMCID: PMC2853846.

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Merritt C, Seydoux G. The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells. Development. 2010 Jun;137(11):1787-98. doi: 10.1242/dev.050799. Epub 2010 Apr 28. PubMed PMID: 20431119; PubMed Central PMCID: PMC2867315.

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Gallo CM, Wang JT, Motegi F, Seydoux G. Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans. Science. 2010 Dec 17;330(6011):1685-9. doi: 10.1126/science.1193697. Epub 2010 Dec 2. PubMed PMID: 21127218; PubMed Central PMCID: PMC3072820.