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Blaser BW, Zon LI. Making HSCs in vitro: don't forget the hemogenic endothelium. Blood. 2018 Sep 27;132(13):1372-1378. doi: 10.1182/blood-2018-04-784140. Epub 2018 Aug 8. Review. PubMed PMID: 30089629; PubMed Central PMCID: PMC6161767.
Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI. CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. J Exp Med. 2017 Apr 3;214(4):1011-1027. doi: 10.1084/jem.20161616. Epub 2017 Mar 28. PubMed PMID: 28351983; PubMed Central PMCID: PMC5379982.
Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. J Vis Exp. 2016 Jun 11;(112). doi: 10.3791/54168. PubMed PMID: 27341538; PubMed Central PMCID: PMC4927786.
Blaser BW, Kim HT, Alyea EP 3rd, Ho VT, Cutler C, Armand P, Koreth J, Antin JH, Plutzky J, Soiffer RJ. Hyperlipidemia and statin use after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2012 Apr;18(4):575-83. doi: 10.1016/j.bbmt.2011.08.003. Epub 2011 Aug 11. PubMed PMID: 21839706; PubMed Central PMCID: PMC3805283.
Guimond M, Freud AG, Mao HC, Yu J, Blaser BW, Leong JW, Vandeusen JB, Dorrance A, Zhang J, Mackall CL, Caligiuri MA. In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis. J Immunol. 2010 Mar 15;184(6):2769-75. doi: 10.4049/jimmunol.0900685. Epub 2010 Feb 8. PubMed PMID: 20142363; PubMed Central PMCID: PMC2924750.
Yokohama A, Mishra A, Mitsui T, Becknell B, Johns J, Curphey D, Blaser BW, Vandeusen JB, Mao H, Yu J, Caligiuri MA. A novel mouse model for the aggressive variant of NK cell and T cell large granular lymphocyte leukemia. Leuk Res. 2010 Feb;34(2):203-9. doi: 10.1016/j.leukres.2009.06.031. Epub 2009 Aug 5. PubMed PMID: 19660811; PubMed Central PMCID: PMC2814907.
Romagné F, André P, Spee P, Zahn S, Anfossi N, Gauthier L, Capanni M, Ruggeri L, Benson DM Jr, Blaser BW, Della Chiesa M, Moretta A, Vivier E, Caligiuri MA, Velardi A, Wagtmann N. Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood. 2009 Sep 24;114(13):2667-77. doi: 10.1182/blood-2009-02-206532. Epub 2009 Jun 24. PubMed PMID: 19553639; PubMed Central PMCID: PMC2756126.
Trotta R, Ciarlariello D, Dal Col J, Allard J 2nd, Neviani P, Santhanam R, Mao H, Becknell B, Yu J, Ferketich AK, Thomas B, Modi A, Blaser BW, Perrotti D, Caligiuri MA. The PP2A inhibitor SET regulates natural killer cell IFN-gamma production. J Exp Med. 2007 Oct 1;204(10):2397-405. doi: 10.1084/jem.20070419. Epub 2007 Sep 17. PubMed PMID: 17875674; PubMed Central PMCID: PMC2118465.
Blaser BW, Gonit M, Qi H, Shatnawi A, Guimond M, Lee RJ, Ratnam M. Induction of folate receptor type beta in a bone marrow engraftment model of acute myelogenous leukemia. Leukemia. 2007 Oct;21(10):2233-5. doi: 10.1038/sj.leu.2404786. Epub 2007 Jun 7. PubMed PMID: 17554378.
Wang L, Wang J, Blaser BW, Duchemin AM, Kusewitt DF, Liu T, Caligiuri MA, Briesewitz R. Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia. Blood. 2007 Sep 15;110(6):2075-83. doi: 10.1182/blood-2007-02-071266. Epub 2007 May 30. PubMed PMID: 17537993.
Neviani P, Santhanam R, Oaks JJ, Eiring AM, Notari M, Blaser BW, Liu S, Trotta R, Muthusamy N, Gambacorti-Passerini C, Druker BJ, Cortes J, Marcucci G, Chen CS, Verrills NM, Roy DC, Caligiuri MA, Bloomfield CD, Byrd JC, Perrotti D. FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia. J Clin Invest. 2007 Sep;117(9):2408-21. doi: 10.1172/JCI31095. PubMed PMID: 17717597; PubMed Central PMCID: PMC1950458.
Becknell B, Hughes TL, Freud AG, Blaser BW, Yu J, Trotta R, Mao HC, Caligiuri de Jesús ML, Alghothani M, Benson DM Jr, Lehman A, Jarjoura D, Perrotti D, Bates MD, Caligiuri MA. Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells. Blood. 2007 Mar 15;109(6):2481-7. doi: 10.1182/blood-2006-10-050096. Epub 2006 Nov 16. PubMed PMID: 17110450; PubMed Central PMCID: PMC1852195.
Blaser BW, Schwind NR, Karol S, Chang D, Shin S, Roychowdhury S, Becknell B, Ferketich AK, Kusewitt DF, Blazar BR, Caligiuri MA. Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity. Blood. 2006 Oct 1;108(7):2463-9. doi: 10.1182/blood-2006-04-019059. Epub 2006 Jun 6. PubMed PMID: 16757683; PubMed Central PMCID: PMC1895554.
Richards JO, Chang X, Blaser BW, Caligiuri MA, Zheng P, Liu Y. Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood. 2006 Jul 1;108(1):246-52. doi: 10.1182/blood-2005-11-4535. Epub 2006 Mar 23. PubMed PMID: 16556890; PubMed Central PMCID: PMC1895835.
Pichiorri F, Trapasso F, Palumbo T, Aqeilan RI, Drusco A, Blaser BW, Iliopoulos D, Caligiuri MA, Huebner K, Croce CM. Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3494-501. doi: 10.1158/1078-0432.CCR-05-2581. PubMed PMID: 16740775.
Yu J, Wei M, Becknell B, Trotta R, Liu S, Boyd Z, Jaung MS, Blaser BW, Sun J, Benson DM Jr, Mao H, Yokohama A, Bhatt D, Shen L, Davuluri R, Weinstein M, Marcucci G, Caligiuri MA. Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells. Immunity. 2006 May;24(5):575-90. doi: 10.1016/j.immuni.2006.03.016. PubMed PMID: 16713975.
Notari M, Neviani P, Santhanam R, Blaser BW, Chang JS, Galietta A, Willis AE, Roy DC, Caligiuri MA, Marcucci G, Perrotti D. A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation. Blood. 2006 Mar 15;107(6):2507-16. doi: 10.1182/blood-2005-09-3732. Epub 2005 Nov 17. PubMed PMID: 16293596; PubMed Central PMCID: PMC1895740.
VanDeusen JB, Shah MH, Becknell B, Blaser BW, Ferketich AK, Nuovo GJ, Ahmer BM, Durbin J, Caligiuri MA. STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivo. Eur J Immunol. 2006 Mar;36(3):623-30. doi: 10.1002/eji.200535241. PubMed PMID: 16482512.
Blaser BW, Caligiuri MA. Autologous immune strategies to reduce the risk of leukemic relapse: consideration for IL-15. Best Pract Res Clin Haematol. 2006;19(2):281-92. doi: 10.1016/j.beha.2005.11.004. Review. PubMed PMID: 16516125.
Neviani P, Santhanam R, Trotta R, Notari M, Blaser BW, Liu S, Mao H, Chang JS, Galietta A, Uttam A, Roy DC, Valtieri M, Bruner-Klisovic R, Caligiuri MA, Bloomfield CD, Marcucci G, Perrotti D. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer Cell. 2005 Nov;8(5):355-68. doi: 10.1016/j.ccr.2005.10.015. PubMed PMID: 16286244.
Roychowdhury S, Blaser BW, Freud AG, Katz K, Bhatt D, Ferketich AK, Bergdall V, Kusewitt D, Baiocchi RA, Caligiuri MA. IL-15 but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease. Blood. 2005 Oct 1;106(7):2433-5. doi: 10.1182/blood-2005-04-1597. Epub 2005 Jun 23. PubMed PMID: 15976176; PubMed Central PMCID: PMC1895258.
Blaser BW, Roychowdhury S, Kim DJ, Schwind NR, Bhatt D, Yuan W, Kusewitt DF, Ferketich AK, Caligiuri MA, Guimond M. Donor-derived IL-15 is critical for acute allogeneic graft-versus-host disease. Blood. 2005 Jan 15;105(2):894-901. doi: 10.1182/blood-2004-05-1687. Epub 2004 Sep 16. PubMed PMID: 15374888.
Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Blaser BW, Freud AG, Chou J, Chen CS, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen CS, Caligiuri MA. Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder. J Natl Cancer Inst. 2004 Oct 6;96(19):1447-57. doi: 10.1093/jnci/djh271. PubMed PMID: 15467034.
Farag SS, Fehniger TA, Becknell B, Blaser BW, Caligiuri MA. New directions in natural killer cell-based immunotherapy of human cancer. Expert Opin Biol Ther. 2003 Apr;3(2):237-50. doi: 10.1517/14712598.3.2.237. Review. PubMed PMID: 12662139.
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