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Nambiar M, Schneider JP. Peptide hydrogels for affinity-controlled release of therapeutic cargo: Current and potential strategies. J Pept Sci. 2021 Nov 7;:e3377. doi: 10.1002/psc.3377. [Epub ahead of print] Review. PubMed PMID: 34747114.
Majumder P, Singh A, Wang Z, Dutta K, Pahwa R, Liang C, Andrews C, Patel NL, Shi J, de Val N, Walsh STR, Jeon AB, Karim B, Hoang CD, Schneider JP. Surface-fill hydrogel attenuates the oncogenic signature of complex anatomical surface cancer in a single application. Nat Nanotechnol. 2021 Nov;16(11):1251-1259. doi: 10.1038/s41565-021-00961-w. Epub 2021 Sep 23. PubMed PMID: 34556833; PubMed Central PMCID: PMC8595541.
Lopez-Silva TL, Schneider JP. From structure to application: Progress and opportunities in peptide materials development. Curr Opin Chem Biol. 2021 Oct;64:131-144. doi: 10.1016/j.cbpa.2021.06.006. Epub 2021 Jul 29. Review. PubMed PMID: 34329941; PubMed Central PMCID: PMC8585687.
Fichman G, Andrews C, Patel NL, Schneider JP. Antibacterial Gel Coatings Inspired by the Cryptic Function of a Mussel Byssal Peptide. Adv Mater. 2021 Oct;33(40):e2103677. doi: 10.1002/adma.202103677. Epub 2021 Aug 22. PubMed PMID: 34423482; PubMed Central PMCID: PMC8492546.
Raskatov JA, Schneider JP, Nilsson BL. Defining the Landscape of the Pauling-Corey Rippled Sheet: An Orphaned Motif Finding New Homes. Acc Chem Res. 2021 May 18;54(10):2488-2501. doi: 10.1021/acs.accounts.1c00084. Epub 2021 Apr 26. Review. PubMed PMID: 33901396; PubMed Central PMCID: PMC8154201.
Fichman G, Schneider JP. Dopamine Self-Polymerization as a Simple and Powerful Tool to Modulate the Viscoelastic Mechanical Properties of Peptide-Based Gels. Molecules. 2021 Mar 4;26(5). doi: 10.3390/molecules26051363. PubMed PMID: 33806346; PubMed Central PMCID: PMC7961423.
Yamada Y, Fichman G, Schneider JP. Serum Protein Adsorption Modulates the Toxicity of Highly Positively Charged Hydrogel Surfaces. ACS Appl Mater Interfaces. 2021 Feb 24;13(7):8006-8014. doi: 10.1021/acsami.0c21596. Epub 2021 Feb 16. PubMed PMID: 33590757.
Fichman G, Schneider JP. Utilizing Frémy's Salt to Increase the Mechanical Rigidity of Supramolecular Peptide-Based Gel Networks. Front Bioeng Biotechnol. 2020;8:594258. doi: 10.3389/fbioe.2020.594258. eCollection 2020. PubMed PMID: 33469530; PubMed Central PMCID: PMC7813677.
Smith SJ, Pauly GT, Hewlett K, Schneider JP, Hughes SH. Structure-based non-nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants. Chem Biol Drug Des. 2021 Jan;97(1):4-17. doi: 10.1111/cbdd.13766. Epub 2020 Sep 17. PubMed PMID: 32743937; PubMed Central PMCID: PMC7821153.
Miller SE, Tsuji K, Abrams RPM, Burke TR Jr, Schneider JP. Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions. J Am Chem Soc. 2020 Nov 25;142(47):19950-19955. doi: 10.1021/jacs.0c07921. Epub 2020 Nov 11. PubMed PMID: 33175531.
Majumder P, Zhang Y, Iglesias M, Fan L, Kelley JA, Andrews C, Patel N, Stagno JR, Oh BC, Furtmüller GJ, Lai CC, Wang YX, Brandacher G, Raimondi G, Schneider JP. Multiphase Assembly of Small Molecule Microcrystalline Peptide Hydrogel Allows Immunomodulatory Combination Therapy for Long-Term Heart Transplant Survival. Small. 2020 Sep;16(38):e2002791. doi: 10.1002/smll.202002791. Epub 2020 Aug 18. PubMed PMID: 32812339; PubMed Central PMCID: PMC7686956.
Nagarkar RP, Fichman G, Schneider JP. Engineering and characterization of apH-sensitive homodimeric antiparallel coiled coil. Peptide Science. 2020 August; :e24180. doi: 10.1002/pep2.24180.
Grkovic T, Akee RK, Thornburg CC, Trinh SK, Britt JR, Harris MJ, Evans JR, Kang U, Ensel S, Henrich CJ, Gustafson KR, Schneider JP, O'Keefe BR. National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library. ACS Chem Biol. 2020 Apr 17;15(4):1104-1114. doi: 10.1021/acschembio.0c00139. Epub 2020 Apr 7. PubMed PMID: 32223208; PubMed Central PMCID: PMC7171602.
Hixon JA, Andrews C, Kashi L, Kohnhorst CL, Senkevitch E, Czarra K, Barata JT, Li W, Schneider JP, Walsh STR, Durum SK. New anti-IL-7Rα monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia. 2020 Jan;34(1):35-49. doi: 10.1038/s41375-019-0531-8. Epub 2019 Aug 22. PubMed PMID: 31439943; PubMed Central PMCID: PMC8132108.
Strope JD, Peer CJ, Sissung TM, Hall OM, Huang PA, Harris EM, Gustafson KR, Henrich CJ, Sigano DM, Pauly GT, Schneider JP, Bates SE, Figg WD. Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain. Cancer Biol Ther. 2020;21(3):223-230. doi: 10.1080/15384047.2019.1683324. Epub 2019 Nov 10. PubMed PMID: 31709896; PubMed Central PMCID: PMC7012088.
Miller SE, Schneider JP. The effect of turn residues on the folding and cell-penetrating activity of beta-hairpin peptides and applications toward protein delivery. Peptide Science. 2020 January; 112(1 SPEC):e24125. doi: 10.1002/pep2.24125.
Miller SE, Yamada Y, Patel N, Suárez E, Andrews C, Tau S, Luke BT, Cachau RE, Schneider JP. Electrostatically Driven Guanidinium Interaction Domains that Control Hydrogel-Mediated Protein Delivery In Vivo. ACS Cent Sci. 2019 Nov 27;5(11):1750-1759. doi: 10.1021/acscentsci.9b00501. Epub 2019 Oct 18. PubMed PMID: 31807676; PubMed Central PMCID: PMC6891851.
Yamada Y, Patel NL, Kalen JD, Schneider JP. Design of a Peptide-Based Electronegative Hydrogel for the Direct Encapsulation, 3D Culturing, in Vivo Syringe-Based Delivery, and Long-Term Tissue Engraftment of Cells. ACS Appl Mater Interfaces. 2019 Sep 25;11(38):34688-34697. doi: 10.1021/acsami.9b12152. Epub 2019 Sep 13. PubMed PMID: 31448901; PubMed Central PMCID: PMC8274941.
Shi J, Schneider JP. De novo Design of Selective Membrane-Active Peptides by Enzymatic Control of Their Conformational Bias on the Cell Surface. Angew Chem Int Ed Engl. 2019 Sep 23;58(39):13706-13710. doi: 10.1002/anie.201902470. Epub 2019 Jul 26. PubMed PMID: 31268617; PubMed Central PMCID: PMC6759387.
Medina SH, Bush B, Cam M, Sevcik E, DelRio FW, Nandy K, Schneider JP. Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer. Biomaterials. 2019 May;202:1-11. doi: 10.1016/j.biomaterials.2019.02.018. Epub 2019 Feb 19. PubMed PMID: 30818087; PubMed Central PMCID: PMC6474249.
Kapur A, Medina SH, Wang W, Palui G, Ji X, Schneider JP, Mattoussi H. Enhanced Uptake of Luminescent Quantum Dots by Live Cells Mediated by a Membrane-Active Peptide. ACS Omega. 2018 Dec 31;3(12):17164-17172. doi: 10.1021/acsomega.8b02918. Epub 2018 Dec 12. PubMed PMID: 30613811; PubMed Central PMCID: PMC6312636.
Majumder P, Baxa U, Walsh STR, Schneider JP. Design of a Multicompartment Hydrogel that Facilitates Time-Resolved Delivery of Combination Therapy and Synergized Killing of Glioblastoma. Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15040-15044. doi: 10.1002/anie.201806483. Epub 2018 Oct 18. PubMed PMID: 30240496; PubMed Central PMCID: PMC6424348.
Kapur A, Medina SH, Wang W, Palui G, Schneider JP, Mattoussi H. Intracellular Delivery of Gold Nanocolloids Promoted by a Chemically Conjugated Anticancer Peptide. ACS Omega. 2018 Oct 31;3(10):12754-12762. doi: 10.1021/acsomega.8b02276. Epub 2018 Oct 8. PubMed PMID: 30411018; PubMed Central PMCID: PMC6210078.
Thornburg CC, Britt JR, Evans JR, Akee RK, Whitt JA, Trinh SK, Harris MJ, Thompson JR, Ewing TL, Shipley SM, Grothaus PG, Newman DJ, Schneider JP, Grkovic T, O'Keefe BR. NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening. ACS Chem Biol. 2018 Sep 21;13(9):2484-2497. doi: 10.1021/acschembio.8b00389. Epub 2018 Jun 13. PubMed PMID: 29812901; PubMed Central PMCID: PMC8130845.
Shi J, Fichman G, Schneider JP. Enzymatic Control of the Conformational Landscape of Self-Assembling Peptides. Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11188-11192. doi: 10.1002/anie.201803983. Epub 2018 Jul 25. PubMed PMID: 29969177; PubMed Central PMCID: PMC6294317.
Gril B, Paranjape AN, Woditschka S, Hua E, Dolan EL, Hanson J, Wu X, Kloc W, Izycka-Swieszewska E, Duchnowska R, Pęksa R, Biernat W, Jassem J, Nayyar N, Brastianos PK, Hall OM, Peer CJ, Figg WD, Pauly GT, Robinson C, Difilippantonio S, Bialecki E, Metellus P, Schneider JP, Steeg PS. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun. 2018 Jul 13;9(1):2705. doi: 10.1038/s41467-018-05030-w. PubMed PMID: 30006619; PubMed Central PMCID: PMC6045677.
Nagarkar RP, Miller SE, Zhong S, Pochan DJ, Schneider JP. Dynamic protein folding at the surface of stimuli-responsive peptide fibrils. Protein Sci. 2018 Jul;27(7):1243-1251. doi: 10.1002/pro.3394. Epub 2018 Mar 14. PubMed PMID: 29493033; PubMed Central PMCID: PMC6032354.
Yamada Y, Chowdhury A, Schneider JP, Stetler-Stevenson WG. Macromolecule-Network Electrostatics Controlling Delivery of the Biotherapeutic Cell Modulator TIMP-2. Biomacromolecules. 2018 Apr 9;19(4):1285-1293. doi: 10.1021/acs.biomac.8b00107. Epub 2018 Mar 19. PubMed PMID: 29505725; PubMed Central PMCID: PMC6329387.
Medina SH, Michie MS, Miller SE, Schnermann MJ, Schneider JP. Fluorous Phase-Directed Peptide Assembly Affords Nano-Peptisomes Capable of Ultrasound-Triggered Cellular Delivery. Angew Chem Int Ed Engl. 2017 Sep 11;56(38):11404-11408. doi: 10.1002/anie.201704649. Epub 2017 Aug 16. PubMed PMID: 28816007; PubMed Central PMCID: PMC5679192.
Sinthuvanich C, Nagy-Smith KJ, Walsh ST, Schneider JP. Triggered Formation of Anionic Hydrogels from Self-Assembling Acidic Peptide Amphiphiles. Macromolecules. 2017 August; 50(15):5643-5651. doi: 10.1021/acs.macromol.7b01056.
Nagy-Smith K, Beltramo PJ, Moore E, Tycko R, Furst EM, Schneider JP. Molecular, Local, and Network-Level Basis for the Enhanced Stiffness of Hydrogel Networks Formed from Coassembled Racemic Peptides: Predictions from Pauling and Corey. ACS Cent Sci. 2017 Jun 28;3(6):586-597. doi: 10.1021/acscentsci.7b00115. Epub 2017 May 31. PubMed PMID: 28691070; PubMed Central PMCID: PMC5492410.
Ishikawa K, Medina SH, Schneider JP, Klar AJS. Glycan Alteration Imparts Cellular Resistance to a Membrane-Lytic Anticancer Peptide. Cell Chem Biol. 2017 Feb 16;24(2):149-158. doi: 10.1016/j.chembiol.2016.12.009. Epub 2017 Jan 12. PubMed PMID: 28089756; PubMed Central PMCID: PMC5316350.
Kapur A, Safi M, Domitrovic T, Medina S, Pauli G, Johnson JE, Schneider J, Mattoussi H. Peptide Mediated Intracellular Delivery of Semiconductor Quantum Dots. COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XII. 2017; 10078:Art. Num. UNSP 100780S. doi: 10.1117/12.2252717.
Bahr JC, Robey RW, Luchenko V, Basseville A, Chakraborty AR, Kozlowski H, Pauly GT, Patel P, Schneider JP, Gottesman MM, Bates SE. Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. Oncotarget. 2016 Oct 25;7(43):69804-69815. doi: 10.18632/oncotarget.12001. PubMed PMID: 27634878; PubMed Central PMCID: PMC5340114.
Schneider J. Synthesis, peptoids and yellow pseudo peptides. Biopolymers. 2016 Sep;106(5):632-3. doi: 10.1002/bip.22982. PubMed PMID: 27658847.
Smith SJ, Pauly GT, Akram A, Melody K, Ambrose Z, Schneider JP, Hughes SH. Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants. J Acquir Immune Defic Syndr. 2016 Aug 15;72(5):485-91. doi: 10.1097/QAI.0000000000001031. PubMed PMID: 27124362; PubMed Central PMCID: PMC4942337.
Yamada Y, Schneider JP. Fragmentation of Injectable Bioadhesive Hydrogels Affords Chemotherapeutic Macromolecules. Biomacromolecules. 2016 Aug 8;17(8):2634-41. doi: 10.1021/acs.biomac.6b00701. Epub 2016 Jul 15. PubMed PMID: 27388026; PubMed Central PMCID: PMC7832078.
Sun JE, Stewart B, Litan A, Lee SJ, Schneider JP, Langhans SA, Pochan DJ. Sustained release of active chemotherapeutics from injectable-solid β-hairpin peptide hydrogel. Biomater Sci. 2016 May 26;4(5):839-48. doi: 10.1039/c5bm00538h. Epub 2016 Feb 24. PubMed PMID: 26906463; PubMed Central PMCID: PMC7802599.
Smac mimicry and the conformational flexibility of a sweet friend. Biopolymers. 2016 May;106(3):234. doi: 10.1002/bip.22872. PubMed PMID: 27163583.
Nagy-Smith K, Yamada Y, Schneider JP. Protein release from highly charged peptide hydrogel networks. J Mater Chem B. 2016 Mar 21;4(11):1999-2007. doi: 10.1039/c5tb02137e. Epub 2016 Feb 26. PubMed PMID: 32263077; PubMed Central PMCID: PMC8244587.
Medina SH, Miller SE, Keim AI, Gorka AP, Schnermann MJ, Schneider JP. An Intrinsically Disordered Peptide Facilitates Non-Endosomal Cell Entry. Angew Chem Int Ed Engl. 2016 Mar 1;55(10):3369-72. doi: 10.1002/anie.201510518. Epub 2016 Feb 2. PubMed PMID: 26835878; PubMed Central PMCID: PMC4820240.
Schneider J. Towards peptide vaccines for influenza. Biopolymers. 2016 Mar;106(2):143. doi: 10.1002/bip.22829. PubMed PMID: 26971565.
Smith SJ, Pauly GT, Akram A, Melody K, Rai G, Maloney DJ, Ambrose Z, Thomas CJ, Schneider JT, Hughes SH. Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants. Retrovirology. 2016 Feb 16;13:11. doi: 10.1186/s12977-016-0244-2. PubMed PMID: 26880034; PubMed Central PMCID: PMC4754833.
Urano E, Ablan SD, Mandt R, Pauly GT, Sigano DM, Schneider JP, Martin DE, Nitz TJ, Wild CT, Freed EO. Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors. Antimicrob Agents Chemother. 2016 Jan;60(1):190-7. doi: 10.1128/AAC.02121-15. Print 2016 Jan. PubMed PMID: 26482309; PubMed Central PMCID: PMC4704169.
Schneider J. Pulsed electron-electron double resonance, peptaibols and chlorotoxin in review. Biopolymers. 2016 Jan;106(1):5. doi: 10.1002/bip.22811. PubMed PMID: 26816387.
Smith DJ, Brat GA, Medina SH, Tong D, Huang Y, Grahammer J, Furtmüller GJ, Oh BC, Nagy-Smith KJ, Walczak P, Brandacher G, Schneider JP. A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels. Nat Nanotechnol. 2016 Jan;11(1):95-102. doi: 10.1038/nnano.2015.238. Epub 2015 Nov 2. PubMed PMID: 26524396; PubMed Central PMCID: PMC4706483.
Schneider J. On-resin macrocycles with the help from a Friend--Histidine. Biopolymers. 2015 Nov;104(6):v. doi: 10.1002/bip.22778. PubMed PMID: 26769296.
Lindsey S, Piatt JH, Worthington P, Sönmez C, Satheye S, Schneider JP, Pochan DJ, Langhans SA. Beta Hairpin Peptide Hydrogels as an Injectable Solid Vehicle for Neurotrophic Growth Factor Delivery. Biomacromolecules. 2015 Sep 14;16(9):2672-83. doi: 10.1021/acs.biomac.5b00541. Epub 2015 Aug 17. PubMed PMID: 26225909; PubMed Central PMCID: PMC4873771.
Nagy-Smith K, Moore E, Schneider J, Tycko R. Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9816-21. doi: 10.1073/pnas.1509313112. Epub 2015 Jul 27. PubMed PMID: 26216960; PubMed Central PMCID: PMC4538636.
Medina SH, Schneider JP. Cancer cell surface induced peptide folding allows intracellular translocation of drug. J Control Release. 2015 Jul 10;209:317-26. doi: 10.1016/j.jconrel.2015.05.267. Epub 2015 May 13. PubMed PMID: 25979324; PubMed Central PMCID: PMC4458427.
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