My Bibliography

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Chen B, Prabhu A, Li G, Kaltenbach A, Wang Y, Shakir G, Natarelli L, Megens R, Jansen Y, Ramanathan S, Geiger M, Faussner A, Hristov M, Richter D, Di X, van der Stelt M, Triantafyllidou V, Li Z, Sachs N, Paloschi V, Maegdefessel L, Hofmann SM, Schifferer M, Simons M, Weber C, Santovito D, Herzig S, Guillamat Prats R, Steffens S. Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake. Nat Commun. 2026 Jul 7;17(1). doi: 10.1038/s41467-026-75214-2. PubMed PMID: 42414306; PubMed Central PMCID: PMC13342577.

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Marie-Theres Dinges S, Schwedhelm E, Baldassarri F, Haller B, Gevaert AB, Böger R, Winzer EB, Edelmann F, Wisløff U, Adams V, Pieske B, Van Craenenbroeck EM, Halle M, Hofmann SM, Mueller-Stegner S. Correction: Circulating nitric oxide pathway metabolites in heart failure with preserved ejection fraction: a sex-stratified cross-sectional analysis. Biol Sex Differ. 2026 Jul 6;17(1). doi: 10.1186/s13293-026-00944-3. PubMed PMID: 42410611; PubMed Central PMCID: PMC13335291.

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Schrenk M, Nowak E, Vogel F, Krüger L, Stüfchen I, Oettle M, Apaydin T, Bobrowicz M, Bidlingmaier M, Garcia-Angarita N, Hofmann SM, Dinges SM, Reisch N, Siebenbürger G, Halle M, Reincke M, Schoser B. Myopathy in endogenous Cushing's syndrome: type II muscle fiber atrophy and its association with age and circulating IGF-1. Endocr Connect. 2026 Jul 1;15(7). doi: 10.1530/EC-26-0355. PubMed PMID: 42447053; PubMed Central PMCID: PMC13393306.

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Pathak E, Tom RZ, Kim M, Sachs S, Zhang Y, Walter M, Pfluger PT, Feuchtinger A, Dyar KA, Bergman BC, Pleitez MA, Lutter D, Hofmann SM. Spatial transcriptomics maps distinct signatures of human intermuscular adipose expansion in mice. medRxiv. 2026 Jun 26;. doi: 10.64898/2026.04.16.26351017. PubMed PMID: 42064925; PubMed Central PMCID: PMC13127531.

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Dinges SM, Schwedhelm E, Baldassarri F, Haller B, Gevaert AB, Böger R, Winzer EB, Edelmann F, Wisløff U, Adams V, Pieske B, Van Craenenbroeck EM, Halle M, Hofmann SM, Mueller-Stegner S. Circulating nitric oxide pathway metabolites in heart failure with preserved ejection fraction: a sex-stratified cross-sectional analysis. Biol Sex Differ. 2026 Jun 15;17(1). doi: 10.1186/s13293-026-00940-7. PubMed PMID: 42298662; PubMed Central PMCID: PMC13270708.

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Singh I, Onogi Y, Menezes F, Khasanova D, Kang L, Wang C, Ruiz-Trave J, Sharma S, Khalil A, Reichenbach VK, Shi Y, Flatley A, Yan X, Israel A, Dragano NRV, Aguilar-Pimentel JA, Hoffmann A, Ghosh A, Noé F, Wolfrum C, Cucuruz S, König AC, Burtscher I, Hauck SM, Lickert H, Hofmann SM, Feederle R, Schriever SC, Hernandez-Bautista R, Sancar G, Cebrian-Serrano A, Tetko I, Fuchs H, Gailus-Durner V, Blüher M, Hrabě de Angelis M, Ussar S. NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo. EMBO J. 2025 Sep;44(18):5037-5065. doi: 10.1038/s44318-025-00520-2. Epub 2025 Aug 1. PubMed PMID: 40750702; PubMed Central PMCID: PMC12436663.

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Sachs S, Götz A, Finan B, Feuchtinger A, DiMarchi RD, Döring Y, Weber C, Tschöp MH, Müller TD, Hofmann SM. Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol. 2024 Sep 12;23(1):341. doi: 10.1186/s12933-024-02407-8. PubMed PMID: 39267039; PubMed Central PMCID: PMC11395572.

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Huang S, He H, Tom RZ, Glasl S, Anzenhofer P, Stiel AC, Hofmann SM, Ntziachristos V. Non-invasive optoacoustic imaging of dermal microcirculatory revascularization in diet-induced obese mice undergoing exercise intervention. Photoacoustics. 2024 Aug;38:100628. doi: 10.1016/j.pacs.2024.100628. eCollection 2024 Aug. PubMed PMID: 39055739; PubMed Central PMCID: PMC11269314.

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Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker DJ, Finan B, Grandl G, Gutgesell R, Hofmann SM, Khalil A, Liu X, Cota P, Bakhti M, Czarnecki O, Bastidas-Ponce A, Lickert H, Kang L, Maity G, Novikoff A, Parlee S, Pathak E, Schriever SC, Sterr M, Ussar S, Zhang Q, DiMarchi R, Tschöp MH, Pfluger PT, Douros JD, Müller TD. Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice. Mol Metab. 2024 May;83:101915. doi: 10.1016/j.molmet.2024.101915. Epub 2024 Mar 14. PubMed PMID: 38492844; PubMed Central PMCID: PMC10973979.

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Liskiewicz A, Khalil A, Liskiewicz D, Novikoff A, Grandl G, Maity-Kumar G, Gutgesell RM, Bakhti M, Bastidas-Ponce A, Czarnecki O, Makris K, Lickert H, Feuchtinger A, Tost M, Coupland C, Ständer L, Akindehin S, Prakash S, Abrar F, Castelino RL, He Y, Knerr PJ, Yang B, Hogendorf WFJ, Zhang S, Hofmann SM, Finan B, DiMarchi RD, Tschöp MH, Douros JD, Müller TD. Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice. Nat Metab. 2023 Dec;5(12):2075-2085. doi: 10.1038/s42255-023-00931-7. Epub 2023 Nov 9. PubMed PMID: 37946085; PubMed Central PMCID: PMC10730394.

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Becker M, Joseph SS, Garcia-Carrizo F, Tom RZ, Opaleva D, Serr I, Tschöp MH, Schulz TJ, Hofmann SM, Daniel C. Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration. Cell Metab. 2023 Oct 3;35(10):1736-1751.e7. doi: 10.1016/j.cmet.2023.08.010. Epub 2023 Sep 20. PubMed PMID: 37734370; PubMed Central PMCID: PMC10563138.

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Sachs S, Götz A, Finan B, Feuchtinger A, DiMarchi RD, Döring Y, Weber C, Tschöp MH, Müller TD, Hofmann SM. GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol. 2023 Aug 17;22(1):217. doi: 10.1186/s12933-023-01940-2. PubMed PMID: 37592302; PubMed Central PMCID: PMC10436634.

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Alfaro AJ, Dittner C, Becker J, Loft A, Mhamane A, Maida A, Georgiadi A, Tsokanos FF, Klepac K, Molocea CE, El-Merahbi R, Motzler K, Geppert J, Karikari RA, Szendrödi J, Feuchtinger A, Hofmann S, Karaca S, Urlaub H, Berriel Diaz M, Melchior F, Herzig S. Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism. EMBO Rep. 2023 Oct 9;24(10):e55981. doi: 10.15252/embr.202255981. Epub 2023 Aug 10. PubMed PMID: 37560809; PubMed Central PMCID: PMC10561358.

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Lutter D, Sachs S, Walter M, Kerege A, Perreault L, Kahn DE, Wolide AD, Kleinert M, Bergman BC, Hofmann SM. Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response. Diabetologia. 2023 May;66(5):873-883. doi: 10.1007/s00125-023-05874-y. Epub 2023 Feb 15. PubMed PMID: 36790478; PubMed Central PMCID: PMC10036433.

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Fasoula NA, Karlas A, Prokopchuk O, Katsouli N, Bariotakis M, Liapis E, Goetz A, Kallmayer M, Reber J, Novotny A, Friess H, Ringelhan M, Schmid R, Eckstein HH, Hofmann S, Ntziachristos V. Non-invasive multispectral optoacoustic tomography resolves intrahepatic lipids in patients with hepatic steatosis. Photoacoustics. 2023 Feb;29:100454. doi: 10.1016/j.pacs.2023.100454. eCollection 2023 Feb. PubMed PMID: 36794122; PubMed Central PMCID: PMC9922962.

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Maity-Kumar G, Ständer L, DeAngelis M, Lee S, Molenaar A, Becker L, Garrett L, Amerie OV, Hoelter SM, Wurst W, Fuchs H, Feuchtinger A, Gailus-Durner V, Garcia-Caceres C, Othman AE, Brockmann C, Schöffling VI, Beiser K, Krude H, Mroz PA, Hofmann S, Tuckermann J, DiMarchi RD, Hrabe de Angelis M, Tschöp MH, Pfluger PT, Müller TD. Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome. Mol Metab. 2022 Dec;66:101616. doi: 10.1016/j.molmet.2022.101616. Epub 2022 Oct 18. PubMed PMID: 36270613; PubMed Central PMCID: PMC9626936.

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Quarta C, Stemmer K, Novikoff A, Yang B, Klingelhuber F, Harger A, Bakhti M, Bastidas-Ponce A, Baugé E, Campbell JE, Capozzi M, Clemmensen C, Collden G, Cota P, Douros J, Drucker DJ, DuBois B, Feuchtinger A, Garcia-Caceres C, Grandl G, Hennuyer N, Herzig S, Hofmann SM, Knerr PJ, Kulaj K, Lalloyer F, Lickert H, Liskiewicz A, Liskiewicz D, Maity G, Perez-Tilve D, Prakash S, Sanchez-Garrido MA, Zhang Q, Staels B, Krahmer N, DiMarchi RD, Tschöp MH, Finan B, Müller TD. GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice. Nat Metab. 2022 Aug;4(8):1071-1083. doi: 10.1038/s42255-022-00617-6. Epub 2022 Aug 22. PubMed PMID: 35995995; PubMed Central PMCID: PMC9398908.

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Hofmann SM, Landgraf R. Research in metabolic ageing - a tale of mice versus humans?. Nat Rev Endocrinol. 2022 Jan;18(1):7-8. doi: 10.1038/s41574-021-00597-9. PubMed PMID: 34824384.

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Huang S, Blutke A, Feuchtinger A, Klemm U, Zachariah Tom R, Hofmann SM, Stiel AC, Ntziachristos V. Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice. EMBO Mol Med. 2021 Sep 7;13(9):e13490. doi: 10.15252/emmm.202013490. Epub 2021 Aug 19. PubMed PMID: 34411447; PubMed Central PMCID: PMC8422073.

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Zhang Q, Delessa CT, Augustin R, Bakhti M, Colldén G, Drucker DJ, Feuchtinger A, Caceres CG, Grandl G, Harger A, Herzig S, Hofmann S, Holleman CL, Jastroch M, Keipert S, Kleinert M, Knerr PJ, Kulaj K, Legutko B, Lickert H, Liu X, Luippold G, Lutter D, Malogajski E, Medina MT, Mowery SA, Blutke A, Perez-Tilve D, Salinno C, Sehrer L, DiMarchi RD, Tschöp MH, Stemmer K, Finan B, Wolfrum C, Müller TD. The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling. Cell Metab. 2021 Apr 6;33(4):833-844.e5. doi: 10.1016/j.cmet.2021.01.015. Epub 2021 Feb 10. PubMed PMID: 33571454; PubMed Central PMCID: PMC8035082.

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Sachs S, Niu L, Geyer P, Jall S, Kleinert M, Feuchtinger A, Stemmer K, Brielmeier M, Finan B, DiMarchi RD, Tschöp MH, Wewer Albrechtsen N, Mann M, Müller TD, Hofmann SM. Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice. Diabetes Obes Metab. 2021 Jan;23(1):195-207. doi: 10.1111/dom.14215. Epub 2020 Nov 5. PubMed PMID: 33001570.

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Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission. Nat Metab. 2020 Apr;2(4):380. doi: 10.1038/s42255-020-0201-1. PubMed PMID: 33820985.

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Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Targeted pharmacological therapy restores β-cell function for diabetes remission. Nat Metab. 2020 Feb;2(2):192-209. doi: 10.1038/s42255-020-0171-3. Epub 2020 Feb 20. PubMed PMID: 32694693.

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Kleinert M, Sachs S, Habegger KM, Hofmann SM, Müller TD. Glucagon Regulation of Energy Expenditure. Int J Mol Sci. 2019 Oct 30;20(21). doi: 10.3390/ijms20215407. Review. PubMed PMID: 31671603; PubMed Central PMCID: PMC6862306.

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Niu L, Geyer PE, Wewer Albrechtsen NJ, Gluud LL, Santos A, Doll S, Treit PV, Holst JJ, Knop FK, Vilsbøll T, Junker A, Sachs S, Stemmer K, Müller TD, Tschöp MH, Hofmann SM, Mann M. Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease. Mol Syst Biol. 2019 Mar 1;15(3):e8793. doi: 10.15252/msb.20188793. PubMed PMID: 30824564; PubMed Central PMCID: PMC6396370.

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Clemmensen C, Finan B, Müller TD, DiMarchi RD, Tschöp MH, Hofmann SM. Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases. Nat Rev Endocrinol. 2019 Feb;15(2):90-104. doi: 10.1038/s41574-018-0118-x. Review. PubMed PMID: 30446744.

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Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, Lusis AJ. Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. Cell Metab. 2019 Apr 2;29(4):932-949.e4. doi: 10.1016/j.cmet.2018.12.013. Epub 2019 Jan 10. PubMed PMID: 30639359; PubMed Central PMCID: PMC6447452.

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Sachs S, Zarini S, Kahn DE, Harrison KA, Perreault L, Phang T, Newsom SA, Strauss A, Kerege A, Schoen JA, Bessesen DH, Schwarzmayr T, Graf E, Lutter D, Krumsiek J, Hofmann SM, Bergman BC. Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E866-E879. doi: 10.1152/ajpendo.00243.2018. Epub 2019 Jan 8. PubMed PMID: 30620635; PubMed Central PMCID: PMC6580171.

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Gao Y, Vidal-Itriago A, Milanova I, Korpel NL, Kalsbeek MJ, Tom RZ, Kalsbeek A, Hofmann SM, Yi CX. Corrigendum to "Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase" [Molecular Metabolism 7 (2018) 155-160]. Mol Metab. 2019 Feb;20:205. doi: 10.1016/j.molmet.2018.12.006. Epub 2018 Dec 24. PubMed PMID: 30594493; PubMed Central PMCID: PMC6358568.

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Keuper M, Berti L, Raedle B, Sachs S, Böhm A, Fritsche L, Fritsche A, Häring HU, Hrabě de Angelis M, Jastroch M, Hofmann SM, Staiger H. Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin. Mol Metab. 2019 Feb;20:28-37. doi: 10.1016/j.molmet.2018.11.006. Epub 2018 Nov 26. PubMed PMID: 30528280; PubMed Central PMCID: PMC6358537.

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Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH. Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes. Nat Commun. 2018 Nov 20;9(1):4975. doi: 10.1038/s41467-018-07479-1. PubMed PMID: 30459311; PubMed Central PMCID: PMC6246605.

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Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH. Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes. Nat Commun. 2018 Oct 23;9(1):4304. doi: 10.1038/s41467-018-06769-y. PubMed PMID: 30353008; PubMed Central PMCID: PMC6199300.

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Götz A, Lehti M, Donelan E, Striese C, Cucuruz S, Sachs S, Yi CX, Woods SC, Wright SD, Müller TD, Tschöp MH, Gao Y, Hofmann SM. Circulating HDL levels control hypothalamic astrogliosis via apoA-I. J Lipid Res. 2018 Sep;59(9):1649-1659. doi: 10.1194/jlr.M085456. Epub 2018 Jul 10. PubMed PMID: 29991652; PubMed Central PMCID: PMC6121940.

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Renner S, Blutke A, Dobenecker B, Dhom G, Müller TD, Finan B, Clemmensen C, Bernau M, Novak I, Rathkolb B, Senf S, Zöls S, Roth M, Götz A, Hofmann SM, Hrabĕ de Angelis M, Wanke R, Kienzle E, Scholz AM, DiMarchi R, Ritzmann M, Tschöp MH, Wolf E. Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs. Mol Metab. 2018 Oct;16:180-190. doi: 10.1016/j.molmet.2018.06.015. Epub 2018 Jun 28. PubMed PMID: 30017782; PubMed Central PMCID: PMC6157610.

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Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schürmann A, Bakhti M, Klingenspor M, Heiman M, Cherrington AD, Ristow M, Lickert H, Wolf E, Havel PJ, Müller TD, Tschöp MH. Animal models of obesity and diabetes mellitus. Nat Rev Endocrinol. 2018 Mar;14(3):140-162. doi: 10.1038/nrendo.2017.161. Epub 2018 Jan 19. Review. PubMed PMID: 29348476.

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Gao Y, Vidal-Itriago A, Milanova I, Korpel NL, Kalsbeek MJ, Tom RZ, Kalsbeek A, Hofmann SM, Yi CX. Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase. Mol Metab. 2018 Jan;7:155-160. doi: 10.1016/j.molmet.2017.11.003. Epub 2017 Nov 9. PubMed PMID: 29174000; PubMed Central PMCID: PMC5784319.

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Gao Y, Vidal-Itriago A, Kalsbeek MJ, Layritz C, García-Cáceres C, Tom RZ, Eichmann TO, Vaz FM, Houtkooper RH, van der Wel N, Verhoeven AJ, Yan J, Kalsbeek A, Eckel RH, Hofmann SM, Yi CX. Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity. Cell Rep. 2017 Sep 26;20(13):3034-3042. doi: 10.1016/j.celrep.2017.09.008. PubMed PMID: 28954222.

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Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metab. 2017 Oct 3;26(4):620-632.e6. doi: 10.1016/j.cmet.2017.08.023. Epub 2017 Sep 21. PubMed PMID: 28943448.

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Fischer IP, Irmler M, Meyer CW, Sachs SJ, Neff F, Hrabě de Angelis M, Beckers J, Tschöp MH, Hofmann SM, Ussar S. A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue. Int J Obes (Lond). 2018 Mar;42(3):507-517. doi: 10.1038/ijo.2017.224. Epub 2017 Sep 13. PubMed PMID: 28901330; PubMed Central PMCID: PMC5880583.

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Keuper M, Sachs S, Walheim E, Berti L, Raedle B, Tews D, Fischer-Posovszky P, Wabitsch M, Hrabě de Angelis M, Kastenmüller G, Tschöp MH, Jastroch M, Staiger H, Hofmann SM. Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors. Mol Metab. 2017 Oct;6(10):1226-1239. doi: 10.1016/j.molmet.2017.07.008. Epub 2017 Jul 19. PubMed PMID: 29031722; PubMed Central PMCID: PMC5641636.

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Ventura-Clapier R, Dworatzek E, Seeland U, Kararigas G, Arnal JF, Brunelleschi S, Carpenter TC, Erdmann J, Franconi F, Giannetta E, Glezerman M, Hofmann SM, Junien C, Katai M, Kublickiene K, König IR, Majdic G, Malorni W, Mieth C, Miller VM, Reynolds RM, Shimokawa H, Tannenbaum C, D'Ursi AM, Regitz-Zagrosek V. Sex in basic research: concepts in the cardiovascular field. Cardiovasc Res. 2017 Jun 1;113(7):711-724. doi: 10.1093/cvr/cvx066. Review. PubMed PMID: 28472454.

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Jall S, Sachs S, Clemmensen C, Finan B, Neff F, DiMarchi RD, Tschöp MH, Müller TD, Hofmann SM. Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice. Mol Metab. 2017 May;6(5):440-446. doi: 10.1016/j.molmet.2017.02.002. eCollection 2017 May. PubMed PMID: 28462078; PubMed Central PMCID: PMC5404097.

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Tews D, Fromme T, Keuper M, Hofmann SM, Debatin KM, Klingenspor M, Wabitsch M, Fischer-Posovszky P. Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells. Mol Cell Endocrinol. 2017 Mar 5;443:106-113. doi: 10.1016/j.mce.2017.01.015. Epub 2017 Jan 11. PubMed PMID: 28088466.

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Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O. Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance. EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7. PubMed PMID: 28111237; PubMed Central PMCID: PMC5474437.

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Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD. Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Cell. 2016 Oct 20;167(3):843-857.e14. doi: 10.1016/j.cell.2016.09.014. Epub 2016 Oct 6. PubMed PMID: 27720451.

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Klancic T, Woodward L, Hofmann SM, Fisher EA. High density lipoprotein and metabolic disease: Potential benefits of restoring its functional properties. Mol Metab. 2016 May;5(5):321-327. doi: 10.1016/j.molmet.2016.03.001. eCollection 2016 May. Review. PubMed PMID: 27110484; PubMed Central PMCID: PMC4837296.

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Clemmensen C, Finan B, Fischer K, Tom RZ, Legutko B, Sehrer L, Heine D, Grassl N, Meyer CW, Henderson B, Hofmann SM, Tschöp MH, Van der Ploeg LH, Müller TD. Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice. EMBO Mol Med. 2015 Mar;7(3):288-98. doi: 10.15252/emmm.201404508. PubMed PMID: 25652173; PubMed Central PMCID: PMC4364946.

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Hofmann SM, Havel PJ. The good, the bad, and the unknown: Fructose and FGF21. Mol Metab. 2015 Jan;4(1):1-2. doi: 10.1016/j.molmet.2014.11.002. eCollection 2015 Jan. PubMed PMID: 25685684; PubMed Central PMCID: PMC4314528.

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Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms. Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968. PubMed PMID: 23744028; PubMed Central PMCID: PMC3709495.

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