My Bibliography

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Snider DB, Meyerholz DK, Dellon ES, Cortes LM, Karri A, Blikslager AT, Laster S, Käser T, Cruse G. Comparison of histochemical methods for the analysis of eosinophils and mast cells using a porcine model of eosinophilic esophagitis. Front Vet Sci. 2025;12:1540995. doi: 10.3389/fvets.2025.1540995. eCollection 2025. PubMed PMID: 40177668; PubMed Central PMCID: PMC11963769.

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Rose EC, Simon JM, Gomez-Martinez I, Magness ST, Odle J, Blikslager AT, Ziegler AL. Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine. Am J Physiol Gastrointest Liver Physiol. 2025 Mar 1;328(3):G182-G196. doi: 10.1152/ajpgi.00194.2024. Epub 2025 Jan 24. PubMed PMID: 39853303; PubMed Central PMCID: PMC12199839.

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Hellstrom E, McKinney-Aguirre C, Gonzalez L, Ziegler A, Blikslager A. Equine Enteric Glial Culture and Application to the Study of a Neural Inflammatory Mechanism in Equine Colic. J Vis Exp. 2024 Oct 4;(212). doi: 10.3791/67244. PubMed PMID: 39431775.

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Elane GL, Blikslager AT, Mair TS. Trends in the management of horses referred for colic evaluation preceding and during the COVID-19 pandemic (2013-2023). Equine Vet Educ. 2025 Jun;37(6):308-315. doi: 10.1111/eve.14038. Epub 2024 Aug 19. PubMed PMID: 40599687; PubMed Central PMCID: PMC12208670.

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Elane GL, Bauck AG, Hobbs KJ, King A, Fields C, Ziegler A, Blikslager A. Review of venipuncture and intravenous catheterization techniques in pigs. J Am Vet Med Assoc. 2024 Oct 1;262(10):1388-1396. doi: 10.2460/javma.24.03.0169. Print 2024 Oct 1. Review. PubMed PMID: 38906168.

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Boston TE, Wang F, Lin X, Kim SW, Fellner V, Scott MF, Ziegler AL, Van Landeghem L, Blikslager AT, Odle J. Prebiotic galactooligosaccharide improves piglet growth performance and intestinal health associated with alterations of the hindgut microbiota during the peri-weaning period. J Anim Sci Biotechnol. 2024 Jun 13;15(1):88. doi: 10.1186/s40104-024-01047-y. PubMed PMID: 38867260; PubMed Central PMCID: PMC11170840.

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Caldwell ML, Cook CA, Mariant CL, Touvron M, Odle J, Blikslager AT, Ziegler AL, Van Landeghem L. Protocol to culture enteric glial cells from the submucosal and myenteric plexi of neonatal and juvenile pig colons. STAR Protoc. 2024 Jun 21;5(2):103057. doi: 10.1016/j.xpro.2024.103057. Epub 2024 May 18. PubMed PMID: 38762883; PubMed Central PMCID: PMC11133979.

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Ziegler AL, Caldwell ML, Craig SE, Hellstrom EA, Sheridan AE, Touvron MS, Pridgen TA, Magness ST, Odle J, Van Landeghem L, Blikslager AT. Enteric glial cell network function is required for epithelial barrier restitution following intestinal ischemic injury in the early postnatal period. Am J Physiol Gastrointest Liver Physiol. 2024 Mar 1;326(3):G228-G246. doi: 10.1152/ajpgi.00216.2022. Epub 2023 Dec 26. PubMed PMID: 38147796; PubMed Central PMCID: PMC11211042.

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Ruff J, Zetterstrom S, Boone L, Hofmeister E, Smith C, Epstein K, Blikslager A, Fogle C, Burke M. Retrospective analysis of postoperative complications following surgical treatment of ileal impaction in horses managed with manual decompression compared to jejunal enterotomy. Front Vet Sci. 2023;10:1156678. doi: 10.3389/fvets.2023.1156678. eCollection 2023. PubMed PMID: 37180077; PubMed Central PMCID: PMC10173877.

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Hepworth-Warren KL, Erwin SJ, Moore CB, Talbot JR, Young KAS, Neault MJ, Haugland JC, Robertson JB, Blikslager AT. Risk factors associated with an outbreak of equine coronavirus at a large farm in North Carolina. Front Vet Sci. 2023;10:1060759. doi: 10.3389/fvets.2023.1060759. eCollection 2023. PubMed PMID: 36937023; PubMed Central PMCID: PMC10020641.

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Erwin SJ, Blikslager AT, Ziegler AL. Age-Dependent Intestinal Repair: Implications for Foals with Severe Colic. Animals (Basel). 2021 Nov 23;11(12). doi: 10.3390/ani11123337. Review. PubMed PMID: 34944114; PubMed Central PMCID: PMC8697879.

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Hellstrom EA, Ziegler AL, Blikslager AT. Postoperative Ileus: Comparative Pathophysiology and Future Therapies. Front Vet Sci. 2021;8:714800. doi: 10.3389/fvets.2021.714800. eCollection 2021. Review. PubMed PMID: 34589533; PubMed Central PMCID: PMC8473635.

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Rose EC, Odle J, Blikslager AT, Ziegler AL. Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach to Modulate Intestinal Barrier Function. Int J Mol Sci. 2021 Jun 23;22(13). doi: 10.3390/ijms22136729. Review. PubMed PMID: 34201613; PubMed Central PMCID: PMC8268081.

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Slifer ZM, Krishnan BR, Madan J, Blikslager AT. Larazotide acetate: a pharmacological peptide approach to tight junction regulation. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G983-G989. doi: 10.1152/ajpgi.00386.2020. Epub 2021 Apr 21. Review. PubMed PMID: 33881350; PubMed Central PMCID: PMC11735010.

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Enomoto H, Yeatts J, Carbajal L, Krishnan BR, Madan JP, Laumas S, Blikslager AT, Messenger KM. In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model. PLoS One. 2021;16(4):e0249179. doi: 10.1371/journal.pone.0249179. eCollection 2021. PubMed PMID: 33844694; PubMed Central PMCID: PMC8041193.

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Prasher A, Shrivastava R, Dahl D, Sharma-Huynh P, Maturavongsadit P, Pridgen T, Schorzman A, Zamboni W, Ban J, Blikslager A, Dellon ES, Benhabbour SR. Steroid Eluting Esophageal-Targeted Drug Delivery Devices for Treatment of Eosinophilic Esophagitis. Polymers (Basel). 2021 Feb 13;13(4). doi: 10.3390/polym13040557. PubMed PMID: 33668571; PubMed Central PMCID: PMC7917669.

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Gonzalez LM, Baker WT, Hughes FE, Blikslager AT, Fogle CA. Comparison of histomorphometric characteristics of dorsal colon and pelvic flexure biopsy specimens obtained from horses with large colon volvulus that underwent resection. Am J Vet Res. 2020 Nov;81(11):899-903. doi: 10.2460/ajvr.81.11.899. PubMed PMID: 33107753; PubMed Central PMCID: PMC8972794.

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Ziegler AL, Pridgen TA, Blikslager AT. Environmental stressors affect intestinal permeability and repair responses in a pig intestinal ischemia model. Tissue Barriers. 2020 Oct 1;8(4):1832421. doi: 10.1080/21688370.2020.1832421. Epub 2020 Oct 26. PubMed PMID: 33100144; PubMed Central PMCID: PMC7714481.

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Jin Y, Blikslager AT. The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases. Int J Mol Sci. 2020 May 18;21(10). doi: 10.3390/ijms21103550. Review. PubMed PMID: 32443411; PubMed Central PMCID: PMC7278945.

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Krüger L, Pridgen TA, Taylor ER, Garman KS, Blikslager AT. Lubiprostone protects esophageal mucosa from acid injury in porcine esophagus. Am J Physiol Gastrointest Liver Physiol. 2020 Apr 1;318(4):G613-G623. doi: 10.1152/ajpgi.00086.2019. Epub 2020 Feb 18. PubMed PMID: 32068440; PubMed Central PMCID: PMC7191458.

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Slifer ZM, Blikslager AT. The Integral Role of Tight Junction Proteins in the Repair of Injured Intestinal Epithelium. Int J Mol Sci. 2020 Feb 1;21(3). doi: 10.3390/ijms21030972. Review. PubMed PMID: 32024112; PubMed Central PMCID: PMC7036844.

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Plundrich NJ, Smith AR, Borst LB, Snider DB, Käser T, Dellon ES, Blikslager AT, Odle J, Lila MA, Laster SM. Oesophageal eosinophilia accompanies food allergy to hen egg white protein in young pigs. Clin Exp Allergy. 2020 Jan;50(1):95-104. doi: 10.1111/cea.13527. Epub 2019 Nov 26. PubMed PMID: 31702085; PubMed Central PMCID: PMC6930966.

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Ziegler AL, Blikslager AT. Sparing the gut: COX-2 inhibitors herald a new era for treatment of horses with surgical colic. Equine Vet Educ. 2020 Nov;32(11):611-616. doi: 10.1111/eve.13189. Epub 2019 Oct 4. PubMed PMID: 34305336; PubMed Central PMCID: PMC8297937.

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Blikslager AT. Colic Prevention to Avoid Colic Surgery: A Surgeon's Perspective. J Equine Vet Sci. 2019 May;76:1-5. doi: 10.1016/j.jevs.2019.02.023. Epub 2019 Mar 6. Review. PubMed PMID: 31084747.

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Gonzalez LM, Stewart AS, Freund J, Kucera CR, Dekaney CM, Magness ST, Blikslager AT. Preservation of reserve intestinal epithelial stem cells following severe ischemic injury. Am J Physiol Gastrointest Liver Physiol. 2019 Apr 1;316(4):G482-G494. doi: 10.1152/ajpgi.00262.2018. Epub 2019 Feb 4. PubMed PMID: 30714814; PubMed Central PMCID: PMC6483022.

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Manship AJ, Blikslager AT, Elfenbein JR. Disease features of equine coronavirus and enteric salmonellosis are similar in horses. J Vet Intern Med. 2019 Mar;33(2):912-917. doi: 10.1111/jvim.15386. Epub 2019 Jan 10. PubMed PMID: 30632200; PubMed Central PMCID: PMC6430874.

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Jin Y, Ibrahim D, Magness ST, Blikslager AT. Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity. Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1;315(6):G966-G979. doi: 10.1152/ajpgi.00087.2018. Epub 2018 Oct 4. PubMed PMID: 30285466; PubMed Central PMCID: PMC6336945.

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Ziegler AL, Freeman CK, Fogle CA, Burke MJ, Davis JL, Cook VL, Southwood LL, Blikslager AT. Multicentre, blinded, randomised clinical trial comparing the use of flunixin meglumine with firocoxib in horses with small intestinal strangulating obstruction. Equine Vet J. 2019 May;51(3):329-335. doi: 10.1111/evj.13013. Epub 2018 Sep 21. PubMed PMID: 30156312; PubMed Central PMCID: PMC6788450.

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Ziegler AL, Pridgen TA, Mills JK, Gonzalez LM, Van Landeghem L, Odle J, Blikslager AT. Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair. PLoS One. 2018;13(8):e0200674. doi: 10.1371/journal.pone.0200674. eCollection 2018. PubMed PMID: 30138372; PubMed Central PMCID: PMC6107120.

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Stieler Stewart A, Freund JM, Blikslager AT, Gonzalez LM. Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia. J Vis Exp. 2018 May 18;(135). doi: 10.3791/57647. PubMed PMID: 29863654; PubMed Central PMCID: PMC6101266.

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Hill TL, Lascelles BDX, Blikslager AT. Effect of sucralfate on gastric permeability in an ex vivo model of stress-related mucosal disease in dogs. J Vet Intern Med. 2018 Mar;32(2):670-678. doi: 10.1111/jvim.15076. Epub 2018 Feb 20. PubMed PMID: 29460464; PubMed Central PMCID: PMC5866966.

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Burke M, Blikslager A. Advances in Diagnostics and Treatments in Horses with Acute Colic and Postoperative Ileus. Vet Clin North Am Equine Pract. 2018 Apr;34(1):81-96. doi: 10.1016/j.cveq.2017.11.006. Epub 2018 Feb 3. Review. PubMed PMID: 29402479.

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Zhang Q, Ke H, Blikslager A, Fujita T, Yoo D. Type III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling. J Virol. 2018 Feb 15;92(4). doi: 10.1128/JVI.01677-17. Print 2018 Feb 15. PubMed PMID: 29187542; PubMed Central PMCID: PMC5790939.

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Lisowski ZM, Pirie RS, Blikslager AT, Lefebvre D, Hume DA, Hudson NPH. An update on equine post-operative ileus: Definitions, pathophysiology and management. Equine Vet J. 2018 May;50(3):292-303. doi: 10.1111/evj.12801. Epub 2018 Jan 29. Review. PubMed PMID: 29281117.

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Lima HK, Lin X, Jacobi SK, Man C, Sommer J, Flowers W, Blikslager A, Gonzalez L, Odle J. Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts. Curr Dev Nutr. 2018 Mar;2(3):nzx006. doi: 10.3945/cdn.117.001958. eCollection 2018 Mar. PubMed PMID: 30386848; PubMed Central PMCID: PMC6204386.

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Kucera CR, Stranahan LW, Hughes F, Blikslager AT, Gonzalez LM. Protein biomarker of cell proliferation determines survival to discharge in cases of equine large colon volvulus. Equine Vet J. 2018 Jul;50(4):452-456. doi: 10.1111/evj.12767. Epub 2017 Nov 27. PubMed PMID: 29032573; PubMed Central PMCID: PMC5899956.

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Blikslager A, Gonzalez L. Equine Intestinal Mucosal Pathobiology. Annu Rev Anim Biosci. 2018 Feb 15;6:157-175. doi: 10.1146/annurev-animal-030117-014748. Epub 2017 Nov 16. Review. PubMed PMID: 29144770; PubMed Central PMCID: PMC7769316.

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Ziegler AL, Blikslager AT. Impaired intestinal barrier function and relapsing digestive disease: Lessons from a porcine model of early life stress. Neurogastroenterol Motil. 2017 Nov;29(11):1-4. doi: 10.1111/nmo.13216. Review. PubMed PMID: 29052972; PubMed Central PMCID: PMC5940449.

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von Furstenberg RJ, Li J, Stolarchuk C, Feder R, Campbell A, Kruger L, Gonzalez LM, Blikslager AT, Cardona DM, McCall SJ, Henning SJ, Garman KS. Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation. Cell Mol Gastroenterol Hepatol. 2017 Nov;4(3):385-404. doi: 10.1016/j.jcmgh.2017.07.005. eCollection 2017 Nov. PubMed PMID: 28936470; PubMed Central PMCID: PMC5602779.

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Ziegler A, Fogle C, Blikslager A. Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. J Am Vet Med Assoc. 2017 Jun 1;250(11):1271-1274. doi: 10.2460/javma.250.11.1271. Review. PubMed PMID: 28509650; PubMed Central PMCID: PMC5588883.

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Krüger L, Gonzalez LM, Pridgen TA, McCall SJ, von Furstenberg RJ, Harnden I, Carnighan GE, Cox AM, Blikslager AT, Garman KS. Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. Am J Physiol Gastrointest Liver Physiol. 2017 Sep 1;313(3):G180-G191. doi: 10.1152/ajpgi.00036.2017. Epub 2017 Jun 1. PubMed PMID: 28572084; PubMed Central PMCID: PMC5625137.

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Jin Y, Blikslager AT. Intestinal Ischemia-Reperfusion: Rooting for the SOCS?. Dig Dis Sci. 2017 Jan;62(1):4-6. doi: 10.1007/s10620-016-4328-6. PubMed PMID: 27830407; PubMed Central PMCID: PMC5218974.

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Meliopoulos VA, Marvin SA, Freiden P, Moser LA, Nighot P, Ali R, Blikslager A, Reddivari M, Heath RJ, Koci MD, Schultz-Cherry S. Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo. mBio. 2016 Nov 1;7(6). doi: 10.1128/mBio.01494-16. PubMed PMID: 27803180; PubMed Central PMCID: PMC5090040.

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Ziegler A, Gonzalez L, Blikslager A. Large Animal Models: The Key to Translational Discovery in Digestive Disease Research. Cell Mol Gastroenterol Hepatol. 2016 Nov;2(6):716-724. doi: 10.1016/j.jcmgh.2016.09.003. PubMed PMID: 28090566; PubMed Central PMCID: PMC5235339.

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Jin Y, Blikslager AT. Myosin light chain kinase mediates intestinal barrier dysfunction via occludin endocytosis during anoxia/reoxygenation injury. Am J Physiol Cell Physiol. 2016 Dec 1;311(6):C996-C1004. doi: 10.1152/ajpcell.00113.2016. Epub 2016 Oct 19. PubMed PMID: 27760753.

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Thakre-Nighot M, Blikslager AT. Indomethacin induces increase in gastric epithelial tight junction permeability via redistribution of occludin and activation of p38 MAPK in MKN-28 Cells. Tissue Barriers. 2016 Jul-Sep;4(3):e1187325. doi: 10.1080/21688370.2016.1187325. eCollection 2016 Jul-Sep. PubMed PMID: 27583191; PubMed Central PMCID: PMC4993575.

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Fogle J, Jacob M, Blikslager A, Edwards A, Wagner B, Dean K, Fogle C. Comparison of lipopolysaccharides and soluble CD14 measurement between clinically endotoxaemic and nonendotoxaemic horses. Equine Vet J. 2017 Mar;49(2):155-159. doi: 10.1111/evj.12582. Epub 2016 May 6. PubMed PMID: 27060869.

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Lefebvre D, Hudson NP, Elce YA, Blikslager A, Divers TJ, Handel IG, Tremaine WH, Pirie RS. Clinical features and management of equine post operative ileus (POI): Survey of Diplomates of the American Colleges of Veterinary Internal Medicine (ACVIM), Veterinary Surgeons (ACVS) and Veterinary Emergency and Critical Care (ACVECC). Equine Vet J. 2016 Nov;48(6):714-719. doi: 10.1111/evj.12520. Epub 2015 Dec 1. PubMed PMID: 26502215.

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Jin Y, Pridgen TA, Blikslager AT. Pharmaceutical Activation or Genetic Absence of ClC-2 Alters Tight Junctions During Experimental Colitis. Inflamm Bowel Dis. 2015 Dec;21(12):2747-57. doi: 10.1097/MIB.0000000000000550. PubMed PMID: 26332307.

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Jin Y, Blikslager AT. ClC-2 regulation of intestinal barrier function: Translation of basic science to therapeutic target. Tissue Barriers. 2015 Oct-Dec;3(4):e1105906. doi: 10.1080/21688370.2015.1105906. eCollection 2015 Oct-Dec. Review. PubMed PMID: 26716076; PubMed Central PMCID: PMC4681285.